17 Works

12th EURADOS Winter School Radon: Dosimetry, Metrology and Regulation

Arturo Vargas, Annette Röttger, James W. Marsh, Pawel Olko, Martin Dubslaff, Marta García-Talavera, Claudia Grossi, Werner Hofmann, Estelle Rage, Krystian Skubacz & Hannah Wiedner
Abstract: The COUNCIL DIRECTIVE 2013/59/EURATOM of 5 December 2013 laying down basic safety standards for protection against the dangers arising from exposure to ionising radiation addresses radon at workplaces and at homes: Radon is directly addressed in the Basic Safety Standards Directive through Article 54 concerning workplace radon levels, Article 74 concerning indoor radon levels, and Article 103 for the national action plan. The new directive brings significant changes, with respect to the former Directive...

Data from: Economic costs and health-related quality of life for hand, foot and mouth disease (HFMD) patients in China

Yaming Zheng, Mark Jit, Joseph T. Wu, Juan Yang, Kathy Leung, Qiaohong Liao & Hongjie Yu
Background: Hand, foot and mouth disease (HFMD) is a common illness in China that mainly affects infants and children. The objective of this study is to assess the economic cost and health-related quality of life associated with HFMD in China. Method: A telephone survey of caregivers were conducted in 31 provinces across China. Caregivers of laboratory-confirmed HFMD patients who were registered in the national HFMD enhanced surveillance database during 2012-2013 were invited to participate in...

Radon potential for Great Britain version 2.1

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Radon is a natural radioactive gas, which enters buildings from the ground. The joint Public Health England (PHE) –British Geological Survey (BGS) digital dataset Radon Potential for Great Britain provides the current definitive map of radon Affected Areas in Great Britain. Exposure to high concentrations increases the risk of lung cancer. PHE (previously known as the Health Protection Agency or HPA) recommends that radon levels should be reduced in homes where the annual average is...

Visions for Radiation Dosimetry over the Next Two Decades – Strategic Research Agenda of the European Radiation Dosimetry Group

Werner Rühm, Elena Fantuzzi, Roger Harrison, Helmut Schuhmacher, Filip Vanhavere, Joao Alves, Jean-Francois Bottolier-Depois, Paola Fattibene, Željka Knežević, María Antonia Lopez, Sabine Mayer, Saveta Miljanić, Stefan Neumaier, Pawel Olko, Hannes Stadtmann, Rick Tanner & Clemens Woda
Abstract: The European Radiation Dosimetry Group (EURADOS) comprises a self-sustainable network of more than 60 European institutions such as reference and research laboratories, dosimetry services and companies, as well as more than 300 scientists active in the field of radiation dosimetry. The aim of the network is to promote research and development and European cooperation in the field of dosimetry of ionizing radiation and its implementation in routine practice, in order to contribute to compatibility...

A stochastic intracellular model of anthrax infection with spore germination heterogeneity (Computer Codes)

Bevelynn Williams, MARTIN LOPEZ-GARCIA, Joseph J. Gillard, Thomas Laws, Grant Lythe, Jonathan Carruthers, Thomas Finnie & carmen molina-parís
This dataset is related to the paper "A stochastic intracellular model of anthrax infection with spore germination heterogeneity", Frontiers in Immunology. It includes the posterior distribution samples of model parameters, along with computer codes in python to generate Figures 4, 5, 6, 7, 8, and 10 of the paper.

Quality Assurance in Individual Monitoring for External Radiation – Results of EURADOS Survey 2012

P. J. Gilvin, J. G. Alves, C. Chesteres, J. W. E. van Dijk, M. Lehtinen, F. Rossi, B. Vekic & M. A. Chevallier
Abstract: EURADOS Working Group 2 (WG2) on Harmonization of Individual Monitoring is a network of institutions and individual monitoring services (IMSs), built up over the last 20 years, that aims to promote quality, technical excellence and good practice in Europe. In pursuit of these aims, in 2012 WG2 carried out a survey of IMSs in Europe. The survey was sent to about 170 IMS and included questions on: the use of formal quality assurance (QA)...

InterComparison on Internal DOSE Assessment – ICIDOSE 2017 Analysing the intercomparison results

Carlo Maria Castellani, Andor Andrasi, Augusto Giussani, Tamas Pázmándi, Gareth Roberts & George Etherington
Abstract: Internal dose assessment often requires complex processes and judgements. “Technical Recommendations for Monitoring Individuals for Occupational Intakes of Radionuclides” (TECHREC) was developed during 2014 to 2016 as a tool for internal dosimetrists. The TECHREC recommendations have been publishedin the Radiation Protection document series of the European Commission as document RP188 (EC 2018). They aim to encourage harmonisation, to present a complete account of the principles of individual monitoring and internal dosimetry, and to provide...

Data from: The impact of HCV infection duration on HIV disease progression and response to cART amongst HIV seroconverters in the UK

Jamie Inshaw, Clifford Leen, Martin Fisher, Richard Gilson, David Hawkins, Simon Collins, Julie Fox, Ken McLean, Sarah Fidler, Andrew Phillips, Sam Lattimore, Abdel Babiker & Kholoud Porter
Introduction: The effect of HCV infection on HIV disease progression remains unclear; the effect of HCV infection duration on HIV disease progression is unknown. Methods: We used data from a cohort of HIV seroconverters to investigate the effect of HCV infection duration on time from HIV seroconversion to CD4 <350cells/mm3, AIDS or death, censoring at the earlier of cART initiation or last clinic visit, adjusting for confounders and splitting data into follow up periods from...

Indicative atlas of radon potential for Great Britain version 2

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Radon is a natural radioactive gas, which enters buildings from the ground. The joint Public Health England (PHE) –British Geological Survey (BGS) digital Indicative Atlas of radon in Great Britain presents an overview of the results of detailed mapping of radon potential, defined as the estimated percentage of homes in an area above the radon Action Level. Exposure to high concentrations increases the risk of lung cancer. PHE (formerly the Health Protection Agency or HPA)...

A model validation scheme for Monte Carlo simulationsof a medical linear accelerator: geometrical description and dosimetric dataused in the “Linac Action”

Barbara Caccia, Valentin Blidéanu, Maïwenn Le Roy, Hans Rabus & Rick Tanner
Abstract: Radiation therapy has become more complex over the past few years with the use of new techniques like IMRT (Intensity Modulated Radiation Therapy) and stereotactic treatments. Moreover, optimisation of the radiotherapeutic treatment has become a critical point in the overall planning and delivery process due to the trend in dose-escalation with these new techniques and the associated risk for damage to healthy tissue. Typically, in techniques such as IMRT the dose distribution includes steep...

EURADOS Stakeholder Workshop on June 30th, 2016

Rühm Werner, Željka Knežević, Elena Fantuzzi, Roger Harrison, Helmut Schuhmacher, Filip Vanhavere, Joao Alves, Jean-Francois Bottolier-Depois, Paola Fattibene, Phil Gilvin, María Antonia Lopez, Sabine Mayer, Saveta Miljanić, Pawel Olko, Hannes Stadtmann, Rick Tanner, Arturo Vargas & Clemens Woda
Introduction: On June 30th, 2016, the “First EURADOS Stakeholder Workshop” was held at the Helmholtz Center Munich (HMGU) in Neuherberg, Germany. The workshop was jointly organized by the HMGU and the EURADOS Office in conjunction with the 57thEURADOS Council meeting, which took place on June 29thand July 1st, also at the HMGU. In the frame of the “European Joint Programme for the Integration of Radiation Protection Research”, the CONCERT project funded by the European Commission...

Visions for Radiation Dosimetry over the Next Two Decades -Strategic Research Agenda of the European Radiation Dosimetry Group: Version 2020

Jean-François Bottolier-Depois, Isabelle Clairand, Elena Fantuzzi, Paola Fattibene, Roger Harrison, Oliver Hupe, Pawel Olko, Veronika Olšovcová, Werner Rühm, Marco Silari, Rick Tanner & Filip Vanhavere
Introduction: The European Radiation Dosimetry Group (EURADOS) comprises a self-sustainable network of more than 70 European institutions and about 600 scientists active in the field of radiation dosimetry. It was founded in 1981, and was registered in Germany as an “e.V.” (registered society) in 2008. The aim of the network is to promote research and development and European cooperation in the field of dosimetry of ionising radiation. For this, EURADOS has established Working Groups (WGs)...

IDEAS Guidelines (Version 2) for the Estimation of Committed Doses from Incorporation Monitoring Data

C.M. Castellani, J.W. Marsh, C. Hurtgen, E. Blanchardon, P. Berard, A. Giussani & M.A. Lopez
ABstract: Doses from intakes of radionuclides cannot be measured but must be assessed from monitoringdata, such as whole body, urine or faecaldata. Such assessments require applicationofbiokinetic and dosimetric models, and the assessor may well have to make assumptions about factors such as the pattern of intake and properties of the material. Intercomparison exercises (Doerfel 2000) have shown a wide range in doses that can be obtained from the same data set as a result of...

EURADOS Intercomparison 2012 for Neutron Dosemeters

Elena Fantuzzi, Marie-Anne Chevallier, Rodolfo Cruz-Suarez, Marlies Luszik-Bhadra, Sabine Mayer, David J. Thomas, Rick Tanner & Filip Vanhavere
Abstract: EURADOS, within the work performed by Working Group 2 -Harmonization of Individual Monitoring in Europe, has started a self-sustained programme of regular intercomparisons and has successfully executed three intercomparisons for whole body photon dosemeters (IC2008, IC2010, IC2012) and one intercomparison for extremity dosemeters for photon and beta fields (IC2009). In 2012, the EURADOS intercomparison IC2012n was launched for personal neutron dosemeters routinely used to measure personal dose equivalent, Hp(10), in individual monitoring. No systems...

Data from: Seasonal influenza vaccination delivery through community pharmacists in England: evaluation of the London pilot

Katherine Atkins, Albert Jan Van Hoek, Conall Watson, Marc Baguelin, Lethiwe Choga, Anika Patel, Thara Raj, Mark Jit & Ulla Griffiths
Objective: To evaluate the effectiveness and cost of the pan-London pharmacy initiative, a programme that allows administration of seasonal influenza vaccination to eligible patients at pharmacies. Design: We analysed 2013–15 data on vaccination uptake in pharmacies via the Sonar reporting system, and the total vaccination uptake via 2011–15 ImmForm GP reporting system data. We conducted an online survey of London pharmacists who participate in the programme to assess time use data, vaccine choice, investment costs,...

Data from: Epigenome-wide association study of lung function level and its change

Medea Imboden, Matthias Wielscher, Faisal I Rezwan, Andre F S Amaral, Emmanuel Schaffner, Ayoung Jeong, Anna Beckmeyer-Borowko, Sarah E Harris, John M Starr, Ian J Deary, Claudia Flexeder, Melanie Waldenberger, Annette Peters, Holger Schulz, Su Chen, Shadia KHan Sunny, Wilfried J J Karmaus, Yu Jiang, Gertraud Erhart, Florian Kronenberg, Ryan Arathimos, Gemma C Sharp, Alexander John Henderson, Yu Fu, Paivi Piirila … & Nicole M Probst-Hensch
Previous reports link differential DNA methylation (DNAme) to environmental exposures which are associated with lung function. Direct evidence on lung function DNAme is however limited. We undertook an agnostic epigenome-wide association study (EWAS) on pre-bronchodilation lung function and its change in adults. In a discovery-replication EWAS design, DNAme in blood and spirometry were measured twice, six-to-15 years apart, in the same participants of three adult population-based discovery cohorts (n=2,043). Associated DNAme markers (P<5x10-7) were tested...

The use of nanobodies in a sensitive ELISA test for SARS-CoV-2 Spike 1 protein

Georgina C. Girt, Abirami Lakshminarayanan, Jiandong Huo, Joshua Dormon, Chelsea Norman, Babak Afrough, Adam Harding, William James, Raymond J. Owens & James H. Naismith
A rapid detection method for SARS-CoV-2 spike protein is essential for control of COVID19. We investigated various combinations of engineered nanobodies in a sandwich ELISA to detect the Spike protein of SARS-CoV-2. We have identified an optimal combination of nanobodies. These were selectively functionalised to further improve antigen capture. This dataset contains data from ELISA experiments described in the manuscript. Plate coating of nanobodies for ELISA by passive adsorption vs biotinylation was compared. A series...

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Affiliations

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  • Helmholtz Zentrum München
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  • Belgian Nuclear Research Centre
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  • Rudjer Boskovic Institute
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