7 Works

Data from: Mosaic VSGs and the scale of Trypanosoma brucei antigenic variation

James P. J. Hall, Huanhuan Wang & J. David Barry
A main determinant of prolonged Trypanosoma brucei infection, and hence transmission and success of the parasite, is the interplay between host acquired immunity and antigenic variation of the parasite variant surface glycoprotein (VSG) coat. About 0.1% of trypanosome divisions produce a switch to a different VSG through differential expression of an archive of hundreds of silent VSG genes and pseudogenes, but the patterns and extent of the trypanosome diversity phenotype, particularly in chronic infection, are...

Data from: Evolution on the move: specialization on widespread resources associated with rapid range expansion in response to climate change

Jon R. Bridle, James Buckley, Edward J. Bodsworth & Chris D. Thomas
Generalist species and phenotypes are expected to perform best under rapid environmental change. In contrast to this view that generalists will inherit the Earth, we find that increased specialisation on a single host plant is associated with the recent climate-driven range expansion of the UK Brown Argus butterfly. Field assays of female host plant preference across the UK reveal a diversity of adaptations to host plants in long-established parts of the range, whereas butterflies in...

Data from: Vitamins, stress and growth: the availability of antioxidants in early life influences the expression of cryptic genetic variation

Sin-Yeon Kim, José C. Noguera, Andrea Tato, Alberto Velando & S.-Y. Kim
Environmental inputs during early development can shape the expression of phenotypes, which has long-lasting consequences in physiology and life history of an organism. Here, we study whether experimentally manipulated availability of dietary antioxidants, vitamins C and E, influences the expression of genetic variance for antioxidant defence, endocrine signal and body mass in yellow-legged gull chicks using quantitative genetic models based on full siblings. Our experimental study in a natural population reveals that the expression of...

Data from: When the sun never sets: diverse activity rhythms under continuous daylight in free-living arctic-breeding birds

Silke S. Steiger, Mihai Valcu, Kamiel Spoelstra, Barbara Helm, Martin Wikelski & Bart Kempenaers
Circadian clocks are centrally involved in the regulation of daily behavioural and physiological processes. These clocks are synchronized to the 24 h day by external cues (Zeitgeber), the most important of which is the light–dark cycle. In polar environments, however, the strength of the Zeitgeber is greatly reduced around the summer and winter solstices (continuous daylight or continuous darkness). How animals time their behaviour under such conditions has rarely been studied in the wild. Using...

Data from: Deleterious consequences of antioxidant supplementation on lifespan in a wild-derived mammal

Colin Selman, Jane S. McLaren, Andrew R. Collins, Garry G. Duthie & John R. Speakman
While oxidative damage due to reactive oxygen species (ROS) often increases with advancing age and is associated with many age-related diseases, its causative role in ageing is controversial. In particular, studies that have attempted to modulate ROS-induced damage, either upwards or downward, using antioxidant or genetic approaches, generally do not show a predictable effect on lifespan. Here we investigated whether dietary supplementation with either vitamin E (α-tocopherol) or vitamin C (ascorbic acid) affected oxidative damage...

Data from: Local adaptation with high gene flow: temperature parameters drive adaptation to altitude in the common frog (Rana temporaria)

Anna P. Muir, Roman Biek, Rob Thomas & Barbara K. Mable
Both environmental- and genetic-influences can result in phenotypic variation. Quantifying the relative contributions of local adaptation and phenotypic plasticity to phenotypes is key to understanding the effect of environmental variation on populations. Identifying the selective pressures that drive divergence is an important, but often lacking, next step. High gene flow between high- and low-altitude common frog (Rana temporaria) breeding sites has previously been demonstrated in Scotland. The aim of this study was to assess whether...

Data from: Using genetic variation to infer associations with climate in the common frog, Rana temporaria

Anna P. Muir, Rob Thomas, Roman Biek & Barbara K. Mable
Recent and historical species' associations with climate can be inferred using molecular markers. This knowledge of population and species-level responses to climatic variables can then be used to predict the potential consequences of ongoing climate change. The aim of this study was to predict responses of Rana temporaria to environmental change in Scotland by inferring historical and contemporary patterns of gene flow in relation to current variation in local thermal conditions. We first inferred colonization...

Registration Year

  • 2013

Resource Types

  • Dataset


  • University of Glasgow
  • Royal Zoological Society of Scotland
  • Max Planck Institute for Ornithology
  • University of Aberdeen
  • University of Nottingham
  • Nederlands Instituut voor Ecologie
  • University of Oslo
  • University of York
  • University of Bristol
  • University of Vigo