6 Works

Information Privacy: Not Just GDPR

Danilo Bruschi
The "information rush" which is characterizing the current phase of the information age calls for actions aimed at enforcing the citizens' right to privacy. Since the entire information life-cycle (collection, manipulation, storing) is now carried out by digital technologies, most of such actions consists of the adoption of severe measures (both organizational and technological) aimed at improving the security of computer systems, as in the case of the EU General Data Protection Regulation. Usually, data...

Data from: Revised Airlie House consensus guidelines for design and implementation of ALS clinical trials

Leonard H Van Den Berg, Eric Sorenson, Gary Gronseth, Eric A. Macklin, Jinsy Andrews, Robert H. Baloh, Michael Benatar, James D. Berry, Adriano Chio, Philippe Corcia, Angela Genge, Amelie K. Gubitz, Catherine Lomen-Hoerth, Christopher J. McDermott, Erik P. Pioro, Jeffrey Rosenfeld, Vincenzo Silani, Martin R. Turner, Markus Weber, Benjamin Rix Brooks, Robert G. Miller & Hiroshi Mitsumoto
Objective: To revise the 1999 Airlie House consensus guidelines for the design and implementation of preclinical therapeutic studies and clinical trials in amyotrophic lateral sclerosis (ALS). Methods: A consensus committee comprising 140 key members of the international ALS community (ALS researchers, clinicians, patient representatives, research funding representatives, industry and regulatory agencies) addressed nine areas of need within ALS research: 1. Pre-clinical studies; 2. Biological and phenotypic heterogeneity; 3. Outcome measures; 4. Disease-modifying and symptomatic interventions;...

Amicitia res plurimas continet. Omaggio a Febronia Elia. Presentazione

Antonino De Francesco
Annali della facoltà di Scienze della formazione – Università degli studi di Catania, 18 (2019)

Data from: MHC structuring and divergent allele advantage in a urodele amphibian: a hierarchical multi-scale approach

Lorenzo Talarico, Wieslaw Babik, Silvio Marta, Venusta Pietrocini & Marco Mattoccia
The proteins encoded by extraordinarily polymorphic major histocompatibility complex (MHC) genes are involved in the adaptive immune response. Balancing selection is believed to maintain MHC polymorphism in the long-term, although neutral processes also play a role in shaping MHC diversity. However, the relative contribution of these processes is poorly understood. Here we characterized MHC class II variation of a low-dispersal, pond-breeding newt (Triturus carnifex) over a restricted, geographically structured area. We aimed to: (1) evaluate...

Data from: Evolution of an insect immune barrier through horizontal gene transfer mediated by a parasitic wasp

Angela Amoresano, Paola Varricchio, Ilaria Di Lelio, Pietro Pucci, Luca Gianfranceschi, Anna Illiano, Silvia Caccia, Federica Astarita, David Horner & Francesco Pennacchio
Genome sequencing data have recently demonstrated that eukaryote evolution has been remarkably influenced by the acquisition of a large number of genes by horizontal gene transfer (HGT) across different kingdoms. However, in depth-studies on the physiological traits conferred by these accidental DNA acquisitions are largely lacking. Here we elucidate the functional role of Sl gasmin, a gene of a symbiotic virus of a parasitic wasp that has been transferred to an ancestor of the moth...

Data from: Haemosporidian parasites depress breeding success and plumage coloration in female barn swallows (Hirundo rustica)

Andrea Romano, Riccardo Nodari, Claudio Bandi, Manuela Caprioli, Alessandra Costanzo, Roberto Ambrosini, Diego Rubolini, Marco Parolini, Sara Epis & Nicola Saino
Parasites are major effectors of natural selection and also play a role in sexual selection processes. Haemosporidian blood parasites are common in vertebrates and have been shown to vary in their effects depending on both the parasite and host species, on the host trait investigated as well as on host condition and stage of infection. Here we investigated infection of adult barn swallows (Hirundo rustica) by Plasmodium, Leucocytozoon and Haemoproteus species during the chronic stage...

Registration Year

  • 2019
    6

Resource Types

  • Dataset
    4
  • Text
    2

Affiliations

  • University of Milan
    6
  • Massachusetts General Hospital
    1
  • Stanford University
    1
  • Kantonsspital St. Gallen
    1
  • Columbia University
    1
  • University of Lausanne
    1
  • National Institutes of Health
    1
  • McGill University
    1
  • University of Miami
    1
  • University of Rome Tor Vergata
    1