78 Works

Additional file 1 of Using natural language processing to automatically classify written self-reported narratives by patients with migraine or cluster headache

Nicolas Vandenbussche, Cynthia Van Hee, Véronique Hoste & Koen Paemeleire
Additional file 1. Information for the participant and question asked to each participants (original in Dutch, English translated version added).

Additional file 3 of Using natural language processing to automatically classify written self-reported narratives by patients with migraine or cluster headache

Nicolas Vandenbussche, Cynthia Van Hee, Véronique Hoste & Koen Paemeleire
Additional file 3. Key words per diagnosis for migraine and cluster headache) with absolute value of the chi-squared statistical test.

Additional file 1 of Psychosocial factors related to sleep in adolescents and their willingness to participate in the development of a healthy sleep intervention: a focus group study

Ann Vandendriessche, Maïté Verloigne, Laura Boets, Jolien Joriskes, Ann DeSmet, Karlien Dhondt & Benedicte Deforche
Supplementary Material 1

Consultation of parents and healthcare professionals in end-of-life decision-making for neonates and infants: a population-level mortality follow-back physician survey

Laure Dombrecht, Filip Cools, Joachim Cohen, Luc Deliens, Linde Goossens, Gunnar Naulaers, Kim Beernaert & Kenneth Chambaere
Abstract Background End-of-life decisions with potential life-shortening effect in neonates and infants are common. We aimed to evaluate how often and in what manner neonatologists consult with parents and other healthcare providers in these cases, and whether consultation is dependent on the type of end-of-life decision made. Methods Based on all deaths under the age of one that occurred between September 2016 and December 2017 in Flanders, Belgium, a nationwide mortality follow-back survey was performed....

Additional file 4 of IL-10 producing regulatory B cells are decreased in blood from smokers and COPD patients

Merel Jacobs, Sven Verschraegen, Bihiyga Salhi, Jasper Anckaert, Pieter Mestdagh, Guy G. Brusselle & Ken R. Bracke
Additional file 4. Supplementary Figure 3. IHC stain for IL-10 and CD20 with isotype control. Representative image of IL-10 and CD20 immunohistochemical staining showing A) positive signal for IL-10 (green), CD20 (red), and nuclei (grey), B) negative signal when the tissue section was stained with isotype controls. All images were taken at a 630x magnification. Scale bar length is 10 μm.

Additional file 6 of IL-10 producing regulatory B cells are decreased in blood from smokers and COPD patients

Merel Jacobs, Sven Verschraegen, Bihiyga Salhi, Jasper Anckaert, Pieter Mestdagh, Guy G. Brusselle & Ken R. Bracke
Additional file 6. Supplementary Figure 5. Capacity of magnetically sorted B cells to produce IL-10 upon cigarette-exposure with BAFF inhibition. The capacity of MACS sorted B cells to produce IL-10 upon cigarette smoke exposure with and without the addition of BAFF-Fc-Chimera (inhibition of BAFF) was determined by flow cytometry and ELISA: A) Percentages of IL10+ cells within unstimulated cells, stimulated cells in medium, 5% CSE, and 10% CSE without the addition of BAFF-Fc-Chimera (white) and...

Additional file 4 of Blood transcriptomics to facilitate diagnosis and stratification in pediatric rheumatic diseases – a proof of concept study

My Kieu Ha, Esther Bartholomeus, Luc Van Os, Julie Dandelooy, Julie Leysen, Olivier Aerts, Vasiliki Siozopoulou, Eline De Smet, Jan Gielen, Khadija Guerti, Michel De Maeseneer, Nele Herregods, Bouchra Lechkar, Ruth Wittoek, Elke Geens, Laura Claes, Mahmoud Zaqout, Wendy Dewals, Annelies Lemay, David Tuerlinckx, David Weynants, Koen Vanlede, Gerlant van Berlaer, Marc Raes, Helene Verhelst … & Benson Ogunjimi
Supplementary Material 4

Additional file 5 of Blood transcriptomics to facilitate diagnosis and stratification in pediatric rheumatic diseases – a proof of concept study

My Kieu Ha, Esther Bartholomeus, Luc Van Os, Julie Dandelooy, Julie Leysen, Olivier Aerts, Vasiliki Siozopoulou, Eline De Smet, Jan Gielen, Khadija Guerti, Michel De Maeseneer, Nele Herregods, Bouchra Lechkar, Ruth Wittoek, Elke Geens, Laura Claes, Mahmoud Zaqout, Wendy Dewals, Annelies Lemay, David Tuerlinckx, David Weynants, Koen Vanlede, Gerlant van Berlaer, Marc Raes, Helene Verhelst … & Benson Ogunjimi
Supplementary Material 5

Additional file 2 of IL-10 producing regulatory B cells are decreased in blood from smokers and COPD patients

Merel Jacobs, Sven Verschraegen, Bihiyga Salhi, Jasper Anckaert, Pieter Mestdagh, Guy G. Brusselle & Ken R. Bracke
Additional file 2. Supplementary Figure 1. Gating strategy to identify B cell subsets. Representative example of the gating strategy used to define the following subsets: A) lymphocytes within single cell populations, B) alive CD20+ B cells within lymphocytes, C) CD27 and IgD expression within the total B cells population, D) naïve B cells (CD27-IgD+IgM+), E) natural effector cells (CD27+IgD+IgM+), and F) activated memory B cells (CD27+IgD-IgM+) and class-switched memory B cells (CD27+IgD-IgM-).

Additional file 2 of IL-10 producing regulatory B cells are decreased in blood from smokers and COPD patients

Merel Jacobs, Sven Verschraegen, Bihiyga Salhi, Jasper Anckaert, Pieter Mestdagh, Guy G. Brusselle & Ken R. Bracke
Additional file 2. Supplementary Figure 1. Gating strategy to identify B cell subsets. Representative example of the gating strategy used to define the following subsets: A) lymphocytes within single cell populations, B) alive CD20+ B cells within lymphocytes, C) CD27 and IgD expression within the total B cells population, D) naïve B cells (CD27-IgD+IgM+), E) natural effector cells (CD27+IgD+IgM+), and F) activated memory B cells (CD27+IgD-IgM+) and class-switched memory B cells (CD27+IgD-IgM-).

IL-10 producing regulatory B cells are decreased in blood from smokers and COPD patients

Merel Jacobs, Sven Verschraegen, Bihiyga Salhi, Jasper Anckaert, Pieter Mestdagh, Guy G. Brusselle & Ken R. Bracke
Abstract Background Two opposing B cell subsets have been defined based on their cytokine profile: IL-6 producing effector B cells (B-effs) versus IL-10 producing regulatory B cells (B-regs) that respectively positively or negatively regulate immune responses. B-regs are decreased and/or impaired in many autoimmune diseases and inflammatory conditions. Since there is increasing evidence that links B cells and B cell-rich lymphoid follicles to the pathogenesis of COPD, the aim of this study was to investigate...

Additional file 1 of Adult essential extracorporeal membrane oxygenation (ECMO) skills for use in an e-learning program for ICU physicians, nurses and perfusionists: a consensus by a modified Delphi questionnaire

Harlinde Peperstraete, Annelien Steenhout, Filip De Somer, Pieter Depuydt, Eric Hoste & Isabelle Van Herzeele
Supplementary Material 1

Additional file 3 of Practice of oxygen use in anesthesiology – a survey of the European Society of Anaesthesiology and Intensive Care

Martin Scharffenberg, Thomas Weiss, Jakob Wittenstein, Katharina Krenn, Magdalena Fleming, Peter Biro, Stefan De Hert, Jan F. A. Hendrickx, Daniela Ionescu & Marcelo Gama de Abreu
Additional file 3: Supplementary Table 2. Post-surgical oxygen management by geographical regions.

Data from: Insights in the diagnosis of a retinal arteriovenous malformation

Geraldine Accou, Fanny Nerinckx & Julie De Zaeytijd
Objective: To describe a patient with vitreous hemorrhage due to peripheral retinal ischemia and neovascularization, who was diagnosed with an underlying retinal arteriovenous malformation. Methods: A 15-year old girl presented with sudden-onset painless visual loss in the right eye. She underwent a full ophthalmologic work-up. Results: BCVA was less than 20/400 in the right eye, 20/20 in the left eye. Intraocular pressure and anterior segment examination were unremarkable. Fundoscopy revealed an impenetrable vitreous hemorrhage in...

Blood transcriptomics to facilitate diagnosis and stratification in pediatric rheumatic diseases – a proof of concept study

My Kieu Ha, Esther Bartholomeus, Luc Van Os, Julie Dandelooy, Julie Leysen, Olivier Aerts, Vasiliki Siozopoulou, Eline De Smet, Jan Gielen, Khadija Guerti, Michel De Maeseneer, Nele Herregods, Bouchra Lechkar, Ruth Wittoek, Elke Geens, Laura Claes, Mahmoud Zaqout, Wendy Dewals, Annelies Lemay, David Tuerlinckx, David Weynants, Koen Vanlede, Gerlant van Berlaer, Marc Raes, Helene Verhelst … & Benson Ogunjimi
Abstract Background Transcriptome profiling of blood cells is an efficient tool to study the gene expression signatures of rheumatic diseases. This study aims to improve the early diagnosis of pediatric rheumatic diseases by investigating patients’ blood gene expression and applying machine learning on the transcriptome data to develop predictive models. Methods RNA sequencing was performed on whole blood collected from children with rheumatic diseases. Random Forest classification models were developed based on the transcriptome data...

Additional file 2 of Blood transcriptomics to facilitate diagnosis and stratification in pediatric rheumatic diseases – a proof of concept study

My Kieu Ha, Esther Bartholomeus, Luc Van Os, Julie Dandelooy, Julie Leysen, Olivier Aerts, Vasiliki Siozopoulou, Eline De Smet, Jan Gielen, Khadija Guerti, Michel De Maeseneer, Nele Herregods, Bouchra Lechkar, Ruth Wittoek, Elke Geens, Laura Claes, Mahmoud Zaqout, Wendy Dewals, Annelies Lemay, David Tuerlinckx, David Weynants, Koen Vanlede, Gerlant van Berlaer, Marc Raes, Helene Verhelst … & Benson Ogunjimi
Supplementary Material 2

Additional file 1 of Blood transcriptomics to facilitate diagnosis and stratification in pediatric rheumatic diseases – a proof of concept study

My Kieu Ha, Esther Bartholomeus, Luc Van Os, Julie Dandelooy, Julie Leysen, Olivier Aerts, Vasiliki Siozopoulou, Eline De Smet, Jan Gielen, Khadija Guerti, Michel De Maeseneer, Nele Herregods, Bouchra Lechkar, Ruth Wittoek, Elke Geens, Laura Claes, Mahmoud Zaqout, Wendy Dewals, Annelies Lemay, David Tuerlinckx, David Weynants, Koen Vanlede, Gerlant van Berlaer, Marc Raes, Helene Verhelst … & Benson Ogunjimi
Supplementary Material 1

Additional file 4 of Blood transcriptomics to facilitate diagnosis and stratification in pediatric rheumatic diseases – a proof of concept study

My Kieu Ha, Esther Bartholomeus, Luc Van Os, Julie Dandelooy, Julie Leysen, Olivier Aerts, Vasiliki Siozopoulou, Eline De Smet, Jan Gielen, Khadija Guerti, Michel De Maeseneer, Nele Herregods, Bouchra Lechkar, Ruth Wittoek, Elke Geens, Laura Claes, Mahmoud Zaqout, Wendy Dewals, Annelies Lemay, David Tuerlinckx, David Weynants, Koen Vanlede, Gerlant van Berlaer, Marc Raes, Helene Verhelst … & Benson Ogunjimi
Supplementary Material 4

Blood transcriptomics to facilitate diagnosis and stratification in pediatric rheumatic diseases – a proof of concept study

My Kieu Ha, Esther Bartholomeus, Luc Van Os, Julie Dandelooy, Julie Leysen, Olivier Aerts, Vasiliki Siozopoulou, Eline De Smet, Jan Gielen, Khadija Guerti, Michel De Maeseneer, Nele Herregods, Bouchra Lechkar, Ruth Wittoek, Elke Geens, Laura Claes, Mahmoud Zaqout, Wendy Dewals, Annelies Lemay, David Tuerlinckx, David Weynants, Koen Vanlede, Gerlant van Berlaer, Marc Raes, Helene Verhelst … & Benson Ogunjimi
Abstract Background Transcriptome profiling of blood cells is an efficient tool to study the gene expression signatures of rheumatic diseases. This study aims to improve the early diagnosis of pediatric rheumatic diseases by investigating patients’ blood gene expression and applying machine learning on the transcriptome data to develop predictive models. Methods RNA sequencing was performed on whole blood collected from children with rheumatic diseases. Random Forest classification models were developed based on the transcriptome data...

Use of broad-spectrum antimicrobials for more than 72 h and the detection of multidrug-resistant bacteria in Japanese intensive care units: a multicenter retrospective cohort study

Hideki Yoshida, Takako Motohashi, Liesbet De Bus, Jan De Waele, Akihiro Takaba, Akira Kuriyama, Atsuko Kobayashi, Chie Tanaka, Hideki Hashi, Hideki Hashimoto, Hiroshi Nashiki, Mami Shibata, Masafumi Kanamoto, Masashi Inoue, Satoru Hashimoto, Shinshu Katayama, Shinsuke Fujiwara, Shinya Kameda, Shunsuke Shindo, Taketo Suzuki, Tetsuya Komuro, Toshiomi Kawagishi, Yasumasa Kawano, Yoshihito Fujita, Yoshiko Kida … & Shigeki Fujitani
Abstract Background Large multicenter studies reporting on the association between the duration of broad-spectrum antimicrobial administration and the detection of multidrug-resistant (MDR) bacteria in the intensive care unit (ICU) are scarce. We evaluated the impact of broad-spectrum antimicrobial therapy for more than 72 h on the detection of MDR bacteria using the data from Japanese patients enrolled in the DIANA study. Methods We analyzed the data of ICU patients in the DIANA study (a multicenter...

Use of broad-spectrum antimicrobials for more than 72 h and the detection of multidrug-resistant bacteria in Japanese intensive care units: a multicenter retrospective cohort study

Hideki Yoshida, Takako Motohashi, Liesbet De Bus, Jan De Waele, Akihiro Takaba, Akira Kuriyama, Atsuko Kobayashi, Chie Tanaka, Hideki Hashi, Hideki Hashimoto, Hiroshi Nashiki, Mami Shibata, Masafumi Kanamoto, Masashi Inoue, Satoru Hashimoto, Shinshu Katayama, Shinsuke Fujiwara, Shinya Kameda, Shunsuke Shindo, Taketo Suzuki, Tetsuya Komuro, Toshiomi Kawagishi, Yasumasa Kawano, Yoshihito Fujita, Yoshiko Kida … & Shigeki Fujitani
Abstract Background Large multicenter studies reporting on the association between the duration of broad-spectrum antimicrobial administration and the detection of multidrug-resistant (MDR) bacteria in the intensive care unit (ICU) are scarce. We evaluated the impact of broad-spectrum antimicrobial therapy for more than 72 h on the detection of MDR bacteria using the data from Japanese patients enrolled in the DIANA study. Methods We analyzed the data of ICU patients in the DIANA study (a multicenter...

Additional file 1 of Per- and polyfluoroalkyl substances (PFAS) and neurobehavioral function and cognition in adolescents (2010–2011) and elderly people (2014): results from the Flanders Environment and Health Studies (FLEHS)

Nicolas van Larebeke, Gudrun Koppen, Sam Decraemer, Ann Colles, Liesbeth Bruckers, Elly Den Hond, Eva Govarts, Bert Morrens, Thomas Schettgen, Sylvie Remy, Dries Coertjens, Tim Nawrot, Vera Nelen, Willy Baeyens & Greet Schoeters
Additional file 1 : Table S1. FLEHS-2 campaign on adolescents. List of confounders and potential covariates included in stepwise multiple or logistic regressions. Table S2. FLESH-3 campaign on adults. List of confounders and potential covariates included in stepwise multiple or logistic regressions. Table S3. Association of blood concentrations of perfluoro compounds with ln-transformed cognitive and neuropsychological parameters. Table S4. Association of blood concentrations of perfluoro compounds with non-transformed cognitive and neuropsychological parameters.

Additional file 2 of Psychosocial factors related to sleep in adolescents and their willingness to participate in the development of a healthy sleep intervention: a focus group study

Ann Vandendriessche, Maïté Verloigne, Laura Boets, Jolien Joriskes, Ann DeSmet, Karlien Dhondt & Benedicte Deforche
Supplementary Material 2

Additional file 1 of Psychosocial factors related to sleep in adolescents and their willingness to participate in the development of a healthy sleep intervention: a focus group study

Ann Vandendriessche, Maïté Verloigne, Laura Boets, Jolien Joriskes, Ann DeSmet, Karlien Dhondt & Benedicte Deforche
Supplementary Material 1

Additional file 1 of Practice of oxygen use in anesthesiology – a survey of the European Society of Anaesthesiology and Intensive Care

Martin Scharffenberg, Thomas Weiss, Jakob Wittenstein, Katharina Krenn, Magdalena Fleming, Peter Biro, Stefan De Hert, Jan F. A. Hendrickx, Daniela Ionescu & Marcelo Gama de Abreu
Additional file 1: Supplementary Material 1. Complete set of Questions – Oxygen survey.

Registration Year

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Affiliations

  • Ghent University Hospital
    78
  • Ghent University
    52
  • Vrije Universiteit Brussel
    28
  • University of Antwerp
    24
  • Universitair Ziekenhuis Brussel
    18
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    14
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    12
  • Antwerp University Hospital
    12
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    12
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    12