7 Works

The global distribution of known and undiscovered ant biodiversity

Jamie Kass, Benoit Guénard, Kenneth Dudley, Clinton Jenkins, Fumika Azuma, Brian Fisher, Catherine Parr, Heloise Gibb, John Longino, Philip Ward, Anne Chao, David Lubertazzi, Michael Weiser, Walter Jetz, Robert Guralnick, Rumsaïs Blatrix, James Des Lauriers, David Donoso, Christos Georgiadis, Kiko Gomez, Peter Hawkes, Robert Johnson, John Lattke, Joe MacGown, William Mackay … & Evan Economo
Invertebrates constitute the majority of animal species and are critical for ecosystem functioning and services. Nonetheless, global invertebrate biodiversity patterns and their congruences with vertebrates remain largely unknown. We resolve the first high-resolution (~20-km) global diversity map for a major invertebrate clade, ants, using biodiversity informatics, range modeling, and machine learning to synthesize existing knowledge and predict the distribution of undiscovered diversity. We find that ants and different vertebrate groups have distinct features in their...

A change of PD-1/PD-L1 expression on peripheral T cell subsets correlates with the different stages of Alzheimer's Disease

Ching-Tse Wu, Cheng-I Chu, Feng-Yu Wang, Hui-Yu Yang, Wei-Sung Tseng, Chuang-Rung Chang & Chien-Chung Chang
Abstract Background Immune checkpoints are a set of costimulatory and inhibitory molecules that maintain self-tolerance and regulate immune homeostasis. The expression of immune checkpoints on T cells in malignancy, chronic inflammation, and neurodegenerative diseases has gained increasing attention. Results To characterize immune checkpoints in neurodegenerative diseases, we aimed to examine the expression of the immune checkpoint PD-1/PD-L1 in peripheral T cells in different Alzheimer’s disease (AD) patients. To achieve this aim, sixteen AD patients and...

soundscape_IR: A source separation toolbox for exploring acoustic diversity in soundscapes

Yi-Jen Sun, Shih-Ching Yen & Tzu-Hao Lin
1. Soundscapes contain rich acoustic information associated with animal behaviors, environmental characteristics, and human activities, providing opportunities for predicting biodiversity changes and associated drivers. However, assessing the diversity of animal vocalizations remains challenging due to the interference of environmental and anthropogenic noise. A tool for separating sound sources and delineating changes in acoustic signals is crucial for an effective assessment of acoustic diversity. 2. We present soundscape_IR, an open-source Python toolbox dedicated to soundscape information...

A change of PD-1/PD-L1 expression on peripheral T cell subsets correlates with the different stages of Alzheimer's Disease

Ching-Tse Wu, Cheng-I Chu, Feng-Yu Wang, Hui-Yu Yang, Wei-Sung Tseng, Chuang-Rung Chang & Chien-Chung Chang
Abstract Background Immune checkpoints are a set of costimulatory and inhibitory molecules that maintain self-tolerance and regulate immune homeostasis. The expression of immune checkpoints on T cells in malignancy, chronic inflammation, and neurodegenerative diseases has gained increasing attention. Results To characterize immune checkpoints in neurodegenerative diseases, we aimed to examine the expression of the immune checkpoint PD-1/PD-L1 in peripheral T cells in different Alzheimer’s disease (AD) patients. To achieve this aim, sixteen AD patients and...

A global phylogenomic study of the Thelypteridaceae

Susan Fawcett, Alan Smith, Michael Sundue, Gordon Burleigh, Emily Sessa, Li-Yaung Kuo, Cheng-Wei Chen, Weston Testo, Michael Kessler & David Barrington
The generic classification of the Thelypteridaceae has been the subject of much controversy. Proposed taxonomic systems have varied from recognizing more than 1000 species in the family within the single genus Thelypteris, to systems favoring upwards of 30 genera. Insights on intrafamilial relationships have been gained from recent phylogenetic studies, especially for the Neotropics; however, in the most recent classification, 10 of 30 recognized genera are either non-monophyletic or untested. In the present study, we...

Additional file 1 of A change of PD-1/PD-L1 expression on peripheral T cell subsets correlates with the different stages of Alzheimer's Disease

Ching-Tse Wu, Cheng-I Chu, Feng-Yu Wang, Hui-Yu Yang, Wei-Sung Tseng, Chuang-Rung Chang & Chien-Chung Chang
Additional file 1: Figure 1. Age-matched elderly human volunteers. (A) All subjects in this study were age-matched and included 16 healthy volunteers and 16 AD patients. (B) Patients with mild AD (CDR = 1; n = 10) and moderate AD (CDR = 2; n = 6) were age-matched. The data are shown as the mean ± SD. A Mann‒Whitney U test was used for the comparison. ns: not significant. Figure 2. PD-1-expressing T-cell subsets in...

Additional file 1 of A change of PD-1/PD-L1 expression on peripheral T cell subsets correlates with the different stages of Alzheimer's Disease

Ching-Tse Wu, Cheng-I Chu, Feng-Yu Wang, Hui-Yu Yang, Wei-Sung Tseng, Chuang-Rung Chang & Chien-Chung Chang
Additional file 1: Figure 1. Age-matched elderly human volunteers. (A) All subjects in this study were age-matched and included 16 healthy volunteers and 16 AD patients. (B) Patients with mild AD (CDR = 1; n = 10) and moderate AD (CDR = 2; n = 6) were age-matched. The data are shown as the mean ± SD. A Mann‒Whitney U test was used for the comparison. ns: not significant. Figure 2. PD-1-expressing T-cell subsets in...

Registration Year

  • 2022
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Resource Types

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Affiliations

  • National Tsing Hua University
    7
  • National Taiwan University Hospital
    4
  • National Taiwan University
    3
  • University of Florida
    2
  • Instituto Geofísico de la Escuela Politécnica Nacional
    1
  • University of Michigan–Ann Arbor
    1
  • University of Vermont
    1
  • University of California, Berkeley
    1
  • La Trobe University
    1
  • University of Oklahoma
    1