Supplemental material: Astrocyte biomarkers in Alzheimer’s disease: a systematic review and meta-analysis

Bruna Bellaver, João Pedro Ferrari-Souza, Lucas Uglione Da Ros, Stephen F. Carter, Elena Rodriguez-Vieitez, Agneta Nordberg, Luc Pellerin, Pedro Rosa-Neto, Douglas Teixeira Leffa & Eduardo R. Zimmer
Objective: To perform a systematic review and meta-analysis to determine whether fluid and imaging astrocyte biomarkers are altered in Alzheimer's disease (AD). Methods: PubMed and Web of Science databases were searched for articles reporting fluid or imaging astrocyte biomarkers in AD. Pooled effect sizes were determined with mean differences (SMD) using the Hedge’s G method with random-effects to determine biomarker performance. Adapted questions from QUADAS-2 were applied for quality assessment. A protocol for this study...

Registration Year

  • 2021
    1

Resource Types

  • Dataset
    1

Affiliations

  • Hospital de Clínicas de Porto Alegre
    1
  • University of Cambridge
    1
  • McGill University
    1
  • Federal University of Rio Grande do Sul
    1
  • University of Poitiers
    1
  • Karolinska Institute
    1