6,311 Works

Leading trait dimensions in flood-tolerant plants

Yingji Pan, Ellen Cieraad, Jean Armstrong, William Armstrong, Beverley Clarkson, Ole Pedersen, Eric Visser, Laurentius Voesenek & Peter Van Bodegom
Background and Aims While trait-based approaches have provided critical insights into general plant functioning, we lack a comprehensive quantitative view on plant strategies in flooded conditions. Plants adapted to flooded conditions have specific traits (e.g. root porosity, low root/shoot ratio and shoot elongation) to cope with the environmental stressors including anoxic sediments, and the subsequent presence of phytotoxic compounds. In flooded habitats, plants also respond to potential nutrient and light limitations, e.g. through the expression...

E74 Like ETS Transcription Factor 3 is a Negative Regulator of Pathogenic Lamina Propria T Helper 17.1 Cells in Murine Colitis

Bo Hu, Hao Wang & Fei Xiao
Interleukin-17A (IL-17A)-expressing T cells, including T helper 17 (Th17) and T helper 17.1 (Th17.1) cells, play a significant role in inflammatory bowel diseases (IBDs). Identifying the mechanisms underlying the heterogeneity and plasticity of IL-17A-expressing T cells is crucial for understanding and controlling their pathogenicity. The role of E74 like ETS transcription factor 3 (ELF3) in regulating the pathogenicity of IL-17A-expressing T cells has not been studied before. Dextran sulfate sodium was used to induce acute...

Abiotic niche divergence of hybrid species from their progenitors

Danying Wang, Xiaoting Xu, Haoyu Zhang, Zhenxiang Xi, Jiao Fu, Richard Abbott & Jianquan Liu
Although more frequently discussed recently than previously, the role of ecology in homoploid hybrid and allopolyploid speciation has not been subjected to comparative analysis. We examined abiotic niche divergence of 22 assumed homoploid hybrid species and 60 allopolyploid species from those of their progenitors. Ecological niche modeling (ENM) was employed in an analysis of each species’ fundamental niche, and ordination methods were used in an analysis of realized niches. Both analyses utilized 100, 000 georeferenced...

Three new sesquiterpenes from Ixeris sonchifolia

Meng Tang, Shu-Han Tang, Jin-Yue Huang, Masao Hattori, Ning Zhang, Bo Yang, Xiu-Hong Wu, Hai-Long Zhang & Zhi-Gang Wang
Two new guaiacene-type sesquiterpenes 13α-dihydroixerin acid, ixerin acid and one new secoguaiacene-type sesquiterpene secoixerin Z, along with four known compounds, were separated from ethanol extract of Ixeris sonchifolia. The structures were determined based on the detailed spectroscopic and physicochemical methods. The cytotoxic activity of the isolates was tested against A549 cells. Among them, compound 3 exhibited potent cytotoxicity against A549 cells with the IC50 of 5.6 ± 0.9 µM.

sj-xlsx-5-tct-10.1177_15330338221124658 - Supplemental material for In Vitro and in Vivo Study of the Effect of Osteogenic Pulsed Electromagnetic Fields on Breast and Lung Cancer Cells

Mike Y. Chen, Jing Li, Nianli Zhang, Erik I. Waldorff, James T. Ryaby, Philip Fedor, Yongsheng Jia & Yujun Wang
Supplemental material, sj-xlsx-5-tct-10.1177_15330338221124658 for In Vitro and in Vivo Study of the Effect of Osteogenic Pulsed Electromagnetic Fields on Breast and Lung Cancer Cells by Mike Y. Chen, Jing Li, Nianli Zhang and Erik I. Waldorff, James T. Ryaby, Philip Fedor, Yongsheng Jia, Yujun Wang in Technology in Cancer Research & Treatment

In Vitro and in Vivo Study of the Effect of Osteogenic Pulsed Electromagnetic Fields on Breast and Lung Cancer Cells

Mike Y. Chen, Jing Li, Nianli Zhang, Erik I. Waldorff, James T. Ryaby, Philip Fedor, Yongsheng Jia & Yujun Wang
Introduction: Although there have been significant advances in research and treatments over the past decades, cancer remains a leading cause of morbidity and mortality, mostly due to resistance to standard therapies. Pulsed electromagnetic field (PEMF), a newly emerged therapeutic strategy, has been highly regarded as less invasive and almost safe to patients, is now a clinically accepted form to treat diseases including cancer. Breast and lung cancer are the most prevalent forms of human cancers,...

Patient perception of doctor communication skills and patient trust in rural primary health care: the mediating role of health service quality

Linni Gu, Bo Tian, Yujia Xin, Shengfa Zhang, Jing Li & Zhijun Sun
Abstract Background This study aimed to explore the relationship between communication skills, health service quality, and patient trust in primary health services. Method This study was conducted in village clinics in rural China. A simple random sampling method was used to select volunteer village clinics and patients. In total, 574 participants from 25 village clinics were selected with the help of local health officers and village doctors. The response rate was 90%. Statistical analyses (hierarchical...

Additional file 3 of Facilitators, barriers and strategies for health-system guidance implementation: a critical interpretive synthesis protocol

Qi Wang, Ying Zhu, Shitong Xie, Mohammad Golam Kibria, Qiangqiang Guo, Ahmed Atef Belal, Yanfei Li, Jingyi Zhang, Yaolong Chen, Holger J. Schünemann, Michael G. Wilson, Kehu Yang & John N. Lavis
Additional file 3. Data extraction form.

Additional file 5 of The rhizosphere bacterial community contributes to the nutritional competitive advantage of weedy rice over cultivated rice in paddy soil

Yue Wu, Jian Sun, Pengcheng Yu, Weiliang Zhang, Youze Lin & Dianrong Ma
Additional file 5. Table S3. The relative abundance of functional groups in each of the stands among weedy rice (AW), cultivated rice (AY) and cultivated rice surrounded by weedy rice (WY).

Additional file 5 of The rhizosphere bacterial community contributes to the nutritional competitive advantage of weedy rice over cultivated rice in paddy soil

Yue Wu, Jian Sun, Pengcheng Yu, Weiliang Zhang, Youze Lin & Dianrong Ma
Additional file 5. Table S3. The relative abundance of functional groups in each of the stands among weedy rice (AW), cultivated rice (AY) and cultivated rice surrounded by weedy rice (WY).

Enhance the Efficiency of Graphene-based THz Modulator by Optimizing the Brewster Angle

Xingyue Li, zhaohui zhang, Xiaoyan Zhao, Tianyao Zhang, Luqi Tao, Zhengyong Huang, Ying Li, Xianhao Wu, Lu Yin & Yuan Yuan
The gate-controllable electronical property of graphene provides a possibility of active tuning property for THz modulator. However, the common modulation technology which only depends on voltage cannot solve the problem of power consumption limitation in communication applications. Here, we demonstrated a Brewster angle-controlled graphene-based THz modulator, which could achieve a relatively high modulation depth with low voltage. First, we explored the complex relationships among the Brewster angles, reflection coefficients and the conductivities of graphene. Then,...

Fibrinogen like protein-1 knockdown suppresses the proliferation and metastasis of TU-686 cells and sensitizes laryngeal cancer to LAG-3 blockade

Jiameng Huang, Qiang Huang, Jiyao Xue, Huiqin Liu, Yang Guo, Hui Chen & Liang Zhou
ObjectiveTo detect the expression of fibrinogen like protein-1 (FGL-1) in laryngeal cancer and evaluate its effect on tumor proliferation, metastasis, and antitumor immunity.MethodsELISA and immunohistochemistry were performed to detect FGL-1 expression in laryngeal cancer. The effects of FGL-1 knockdown on the proliferation, cell cycle progression, apoptosis, migration, and invasion of laryngeal cancer cells were evaluated by the CCK-8, colony formation, flow cytometry, Transwell migration, and western blot assays. We detected changes in tumorigenesis and drug...

Additional file 1 of Associations of habitual glucosamine supplementation with incident gout: a large population based cohort study

Mengyi Liu, Ziliang Ye, Yanjun Zhang, Sisi Yang, Qimeng Wu, Chun Zhou, Panpan He, Yuanyuan Zhang, Xiaoqin Gan & Xianhui Qin
Additional file 1: Figure S1. Flow chart of study participants. Figure S2. Association of glucosamine use and the risk of gout stratified by potential risk factors in males. Table S1. Single nucleotide polymorphisms used to build the genetic risk score for gout.

Associations of habitual glucosamine supplementation with incident gout: a large population based cohort study

Mengyi Liu, Ziliang Ye, Yanjun Zhang, Sisi Yang, Qimeng Wu, Chun Zhou, Panpan He, Yuanyuan Zhang, Xiaoqin Gan & Xianhui Qin
Abstract Objectives The association between habitual glucosamine use and incident gout has not been examined in previous studies. We aimed to evaluate the association of habitual use of glucosamine with the risk of gout in general population. Methods A total of 436,594 participants (55.4% female) without prior gout at baseline who completed a questionnaire on supplementation use, which included glucosamine, in the UK Biobank were enrolled. Incident gout was recorded from self-report, death register, primary...

Additional file 1 of Adalimumab for induction of remission in patients with Crohn's disease: a systematic review and meta-analysis

Juntao Yin, Yang Li, Yangyang Chen, Chaoyang Wang & Xiaoyong Song
Additional file 1: Figure S1. Forest plot for failure to achieve clinical remission at 4 weeks subgroup by previous TNF-α exposure in ADA and control groups.

Additional file 3 of Adalimumab for induction of remission in patients with Crohn's disease: a systematic review and meta-analysis

Juntao Yin, Yang Li, Yangyang Chen, Chaoyang Wang & Xiaoyong Song
Additional file 3: Figure S3. Forest plot for failure to achieve clinical response (70-point response) at 4 weeks subgroup by previous TNF-α exposure in ADA and control groups.

Supplemental Material - Factors influencing the performance of virtual reality in urban planning: Evidence from a View corridor Virtual Reality project, Beijing

Huaxiong Jiang, Stan Geertman, Hao Zhang & Shangyi Zhou
Supplemental Material for Factors influencing the performance of virtual reality in urban planning: Evidence from a View corridor Virtual Reality project, Beijing by Huaxiong Jiang, Stan Geertman, Hao Zhang and Shangyi Zhou in Environment and Planning B: Urban Analytics and City Science

Pharmacological mechanism and therapeutic efficacy of Icariside II in the treatment of acute ischemic stroke: a systematic review and network pharmacological analysis

Xu Wang, Jinjian Li, Lifang Liu, Jun-Ming Kan, Ping Niu, Zi-Qiao Yu, Chunyu Ma, Fuxiang Dong, Mo-Xuan Han, Jinhua Li & De-xi Zhao
Abstract Background and objective Epimedii has long been used as a traditional medicine in Asia for the treatment of various common diseases, including Alzheimer's disease, cancer, erectile dysfunction, and stroke. Studies have reported the ameliorative effects of Icariside II (ICS II), a major metabolite of Epimedii, on acute ischemic stroke (AIS) in animal models. Based on network pharmacology, molecular docking, and molecular dynamics (MD) simulations, we conducted a systematic review to evaluate the effects and...

Additional file 1 of Microbiota and metabolites alterations in proximal and distal gastric cancer patients

Yan Yang, Daofeng Dai, Wen Jin, Yingying Huang, Yingzi Zhang, Yiran Chen, Wankun Wang, Wu Lin, Xiangliu Chen, Jing Zhang, Haohao Wang, Haibin Zhang & Lisong Teng
Additional file 1: Table S1. Clinicopathological characteristics of patients with gastric cancer in this study. Table S2. Different microorganisms in Proximal T and Distal T compared to their respective non tumor samples. Table S3. Significant differences in metabolites between Distal T and Distal N. Table S4. Significant differences in metabolites between Proximal T and Proximal N. Table S5. Metabolic pathway enrichment of differential metabolites between Distal T and Distal N. Table S6. Metabolic pathway enrichment...

Additional file 2 of Microbiota and metabolites alterations in proximal and distal gastric cancer patients

Yan Yang, Daofeng Dai, Wen Jin, Yingying Huang, Yingzi Zhang, Yiran Chen, Wankun Wang, Wu Lin, Xiangliu Chen, Jing Zhang, Haohao Wang, Haibin Zhang & Lisong Teng
Additional file 2: Figure S2. The microbial relative abundance of proximal, distal tumor tissues and matched non-tumor tissues at the genus level. Proximal T,proximal GC tumor tissues; Proximal N,proximal GC non-tumor tissues; Distal T, distal GC tumor tissues; Distal N, distal GC non-tumor tissues.

Additional file 3 of The rhizosphere bacterial community contributes to the nutritional competitive advantage of weedy rice over cultivated rice in paddy soil

Yue Wu, Jian Sun, Pengcheng Yu, Weiliang Zhang, Youze Lin & Dianrong Ma
Additional file 3. Table S1. Different bacteria in the groups in the phylum level classifications.

Additional file 3 of The rhizosphere bacterial community contributes to the nutritional competitive advantage of weedy rice over cultivated rice in paddy soil

Yue Wu, Jian Sun, Pengcheng Yu, Weiliang Zhang, Youze Lin & Dianrong Ma
Additional file 3. Table S1. Different bacteria in the groups in the phylum level classifications.

Identification of molecular subtypes based on inflammatory response in lower-grade glioma

Wanzun Lin, Jing Gao, Haojiong Zhang, Li Chen, Xianxin Qiu, Qingting Huang, Jiyi Hu, Lin Kong & Jiade J. Lu
Abstract Background Inflammatory response is an important characteristic affecting prognosis and therapeutic response in lower-grade glioma (LGG). However, the molecular subtypes based on inflammatory response are still under exploitation. Methods The RNA sequencing, somatic mutation, and corresponding clinical data from 1205 LGG patients were obtained from the TCGA, CGGA, and Rembrandt cohorts. Consensus clustering was performed to identify molecular subtypes associated with inflammation. Prognosis, clinicopathologic features, immune cell infiltration, and somatic mutation profile were compared...

Additional file 1 of Inconsistency analysis between metagenomic next-generation sequencing results of cerebrospinal fluid and clinical diagnosis with suspected central nervous system infection

Jin Wang, Jun Ye, Liqi Yang, Xiangfeng Chen, Haoshu Fang, Zhou Liu, Guomei Xia, Yafei Zhang & Zhenhua Zhang
Additional file 1: The results of next generation sequencing of cerebrospinal fluid.

Additional file 2 of Inconsistency analysis between metagenomic next-generation sequencing results of cerebrospinal fluid and clinical diagnosis with suspected central nervous system infection

Jin Wang, Jun Ye, Liqi Yang, Xiangfeng Chen, Haoshu Fang, Zhou Liu, Guomei Xia, Yafei Zhang & Zhenhua Zhang
Additional file 2: Comparison of the etiological results between conventional detection methods and next-generation sequencing technology.

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