2 Works

Data from: The association between method of solicitation and patient permissions for use of surplus tissues and contact for future research

Azza Shoaibi, Jihad S. Obeid, Jim C. Oates, Melissa L. Habrat & Leslie A. Lenert
Objective: Obtaining patient permissions for research contact and for surplus tissue use as part of routine clinical practice can improve research participation. This study aims to investigate the difference in patient permissions for use of surplus tissues, and for direct contact for research, using two different methods of solicitation. Methods: An opt-in, population-based approach for gathering research permissions was implemented in two methods. The first method, applied a 2 –item patient questionnaire delivered through the...

Data from: Effect of IV glyburide on adjudicated edema endpoints in the GAMES-RP Trial

W. Taylor Kimberly, Matthew B. Bevers, Rüdiger Von Kummer, Andrew M. Demchuk, Javier M. Romero, Jordan J. Elm, Holly E. Hinson, Bradley J. Molyneaux, J. Marc Simard & Kevin Navin Sheth
Objective: In this secondary analysis of the GAMES-RP trial, we report the effect of IV glyburide on adjudicated, edema-related endpoints. Methods: Blinded adjudicators assigned designations for hemorrhagic transformation, neurological deterioration, malignant edema and edema-related death to patients from the GAMES-RP Phase II randomized controlled trial of IV glyburide for large hemispheric infarct. Rates of these endpoints were compared between treatment arms in the per-protocol sample. In those participants with malignant edema, the effects of treatment...

Registration Year

  • 2018
    2

Resource Types

  • Dataset
    2

Affiliations

  • Medical University of South Carolina
    2
  • Massachusetts General Hospital
    1
  • Oregon Health & Science University
    1
  • University of Pittsburgh
    1
  • University of Maryland, Baltimore County
    1
  • University of Calgary
    1
  • Brigham and Women's Hospital
    1
  • Yale New Haven Hospital
    1