Supplemental Material for Dynamic response control of centrifugal pendulum vibration absorber with motion-limiting device during startup in gravity field by Yi Zhang, Guangqiang Wu, Yiming Long in Journal of Vibration and Control

Objectives The relationship between prenatal physical activity (PA) and adverse birth outcomes is still inconclusive. We aimed to investigate the association between PA during pregnancy and adverse birth outcomes by using data from the Guangxi Zhuang birth cohort (GZBC) in China. Study Design A total of 11,292 mother-infant pairs were included from GZBC in China. The information on PA status, intensity, adequacy, and volume and birth outcomes were collected. Multivariable linear and logistic regression models...

Adult individuals frequently face difficulties in attracting and keeping mates, which is an important driver of singlehood. In the current research, we investigated the mating performance (i.e., how well people do in attracting and retaining intimate partners) and singlehood status in 14 different countries, namely Austria, Brazil, China, Greece, Hungary, Italy, Japan, Peru, Poland, Russia, Spain, Turkey, the UK, and Ukraine (N = 7,181). We found that poor mating performance was in high occurrence, with...

The solution-based colloidal synthesis of multinary semi-conductor compositions has allowed the design of new inorganic materials impacting a large variety of applications. Yet there are certain compositions that have remained elusive--particularly quaternary structures of transition metal-based (e.g., Co, Zn, Ni, Fe, Mn, and Cr) copper antimony chalcogenides. These are widely sought for tuning the electrical and thermal conductivity as a function of the size, composition, and crystal phase. In this work, a facile hot injection...

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Single-molecule localization microscopy has enabled scientists to visualize cellular structures at the nanometer scale. However, researchers are facing great challenges to analyze images presented by point clouds. Existing algorithms for cluster identification are coordinate-based analyses requiring users to input cutoff thresholds based on the distance or density of the point cloud. These thresholds are often one’s best guess with repeated visual inspections, making the cluster assignment user-dependent. Here, we present a cluster identification algorithm mimicking...

The N-methyl-d-aspartic acid (NMDA) receptors belongs to the family of ionotropic glutamate receptors, which could mediate most excitatory synaptic transmission in the brain. It is interesting to know if some available drugs have regulatory effects on the NMDARs. Herein, the present study reports the discovery of drugs targeting NMDAR using virtual screening. In this study, talniflumate with the EC50 value at 61.49 nM was successfully screened. The interaction analysis of this compound was further explored...

The envelope model is a recently developed methodology for multivariate analysis that enhances estimation accuracy by exploiting the relation between the mean and eigenstructure of the covariance matrix. We extend the envelope model to function-on-function linear regression, where the response and the predictor are assumed to be random functions in Hilbert spaces. We use a double envelope structure to accommodate the eigenstructures of the covariance operators for both the predictor and the response. The central...

The knowledge of impurities is an important issue and the base of quality control in modern drugs. To date, the quality control of the antitumor drug homoharringtonine (HHT) is still not sufficiently solved and needs to be improved. Six main impurities, drupacine, cephalotaxine, desmethylcephalotaxinone, harringtonine, 3-O-acetyl-cephalotaxine and 2'R,3'S-isoharringtonine were traced during HHT drug production by HPLC and LC-MS analyses. Additionally, we were able to isolate and identify three undescribed key trace impurities, neohomoharringtonines A–C. Their...

NASH-related liver transplants are increasing because of the obesity epidemic, but the influence of T2DM on various levels of BMI among NASH recipients is unclear. We analyzed data retrieved from SRTR on 4,515 patients. We divided patients by BMI into five groups: normal weight; overweight; class 1 obesity; class 2 obesity; and class 3 obesity. Statistical analysis was done. Patients in the NASH group with T2DM had a lower patient and graft survival than patients...

Inevitable emergence of acquired resistance to EGFR TKIs including third-generation TKI osimertinib limits their long-term efficacy in treating EGFR-mutant lung cancer. A fuller investigation of novel molecular mechanisms underlying acquired resistance is essential to develop efficacious therapeutic strategies. Consequently, we have identified a novel TGFβ1/integrin β3 loop that contributes to the occurrence of EGFR TKI-acquired resistance. EGFR TKIs dramatically and sustainably increased the expression of both TGFβ1 and integrin β3 in in vitro and in...

Supplemental material, sj-pdf-1-jao-10.1177_03913988221145501 for Establishment of acute liver failure model in Tibetan miniature pig and verified by dual plasma molecular adsorption system by Yi Wang, Chenjie Zhou, Yu Fu, Linya Zhang, Shusong Liu, Lei Cai, Zesheng Jiang, Xiaoping Xu, Lei Feng and Yi Gao in The International Journal of Artificial Organs

Visualization results in different polarization state from a binocular holographic 3D display system

Aim: This meta-analysis aimed to investigate the clinical value of calprotectin in rheumatoid arthritis (RA) patients. Methods: The data regarding blood calprotectin levels in RA patients were retrieved from PubMed, Embase, Web of Science and Cochrane databases. Results: Thirty-one eligible articles were included. Calprotectin was increased in RA patients compared with healthy controls (mean difference [MD] = 1.48, 95% CI: 1.16–1.79). Calprotectin was positively associated with C-reactive protein (correlation coefficient [CC] = 0.58, 95% CI:...

The original meta-analysis of hyperthermic intraperitoneal chemotherapy (HIPEC) is already outdated, owing to the latest trial results. This study aimed to clarify the efficacy and adverse events of cytoreductive surgery with HIPEC compared to conventional therapy for advanced and platinum-sensitive recurrent epithelial ovarian cancer (OC). In this meta-analysis, phase II/III controlled trials regarding ‘HIPEC’ and ‘ovarian cancer’ were searched for in electronic databases from inception to March 2022. Twenty-one studies were included in the quantitative...

The original meta-analysis of hyperthermic intraperitoneal chemotherapy (HIPEC) is already outdated, owing to the latest trial results. This study aimed to clarify the efficacy and adverse events of cytoreductive surgery with HIPEC compared to conventional therapy for advanced and platinum-sensitive recurrent epithelial ovarian cancer (OC). In this meta-analysis, phase II/III controlled trials regarding ‘HIPEC’ and ‘ovarian cancer’ were searched for in electronic databases from inception to March 2022. Twenty-one studies were included in the quantitative...

Soil erosion is a major global soil degradation problem that threatens land, freshwater and oceans. Rainfall erosivity has led to an increasing in the global soil erosion rate, while vegetation restoration is a safeguard measure to reduce soil erosion. Therefore, probing the influence of precipitation and vegetation on the spatial distribution of soil erosion is important for understanding the mechanism of erosion. In order to assess the degree of global soil erosion, based on the...

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Supplemental document

Cancers require telomere maintenance mechanisms for unlimited replicative potential. They achieve this through TERT activation or alternative telomere lengthening associated with ATRX or DAXX loss. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, we dissect whole-genome sequencing data of over 2500 matched tumor-control samples from 36 different tumor types aggregated within the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium to characterize the genomic footprints of these mechanisms. While the...

Supplemental Material for Accuracy of Realigned K-line for Predicting Surgical Outcomes After Laminoplasty in Patients With Degenerative Cervical Myelopathy by Qifei Duan, Guoyan Liang, Chong Chen, Yongyu Ye, Xiaoqing Zheng, Changxiang Liang and Yunbing Chang in Global Spine Journal

BackgroundAnti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis secondary to central nervous system (CNS) infection is a unique subtype of the autoimmune-mediated disease, of which the imaging features are unclear.PurposeTo compare the brain magnetic resonance imaging (MRI) features between the anti-NMDAR encephalitis secondary to CNS infection and that without initial infection.Material and MethodsA total of 70 adult patients with anti-NMDAR encephalitis were retrospectively enrolled (24 in the post-infection group, 46 in the non-infection-related group). Their clinical and imaging features...

1. As a major plant-derived soil organic carbon (SOC) component, lignin phenols are unique biomarkers that reflect biogeochemical characteristics under different vegetation compositions and climatic zones in coastal wetlands. However, the latitudinal patterns of plant-derived lignin phenols to SOC and their link with the stability and controlling mechanisms remain poorly understood. 2. A total of 156 soil samples from 39 sites along a 5000 km coastal transect, were taken to explore the effects of biological...