58 Works

Code lists for: \"Risk of adverse mental health outcomes in women with history of breast cancer: a matched population-based cohort study in the United Kingdom (1988-2018)\"

Helena Carreira & Garth Funston
A set of read codes associated with a paper titled "Risk of adverse mental health outcomes in women with history of breast cancer: a matched population-based cohort study in the United Kingdom (1988-2018)".

Thick adherent diamond films on AlN with low thermal barrier resistance - data

Soumen Mandal, Chao Yuan, Fabien Massabuau, James W Pomeroy, Jerome Cuenca, Henry A Bland, Evan L Thomas, David Wallis, Tim Batten, Rachel Oliver, Martin Kuball & Oliver A Williams
This dataset is the study of thick adherent diamond layers on AlN. The txt files can be opened and analysed using any plotting software. The work describes growth of >100μm thick diamond layer adherent on aluminium nitride. While thick films failed to adhere on untreated AlN films, hydrogen/nitrogen plasma treated AlN films retained the thick diamond layers. Clear differences in zeta potential measurement confirms the surface modification due to hydrogen/nitrogen plasma treatment. Areal Raman maps...

Data from: Virus evolution in Wolbachia-infected Drosophila

Julien Martinez, Gaspar Bruner-Montero, Sophia CL Smith, Jonathan P Day, Ben Longdon, Ramesh Arunkumar & Francis M Jiggins
Wolbachia, a common vertically transmitted symbiont, can protect insects against viral infection and prevent mosquitoes from transmitting viral pathogens. For this reason, Wolbachia-infected mosquitoes are being released to prevent the transmission of dengue and other arboviruses. An important question for the long-term success of these programs is whether viruses can evolve to escape the antiviral effects of Wolbachia. We have found that Wolbachia altered the outcome of competition between strains of the DCV virus in...

Optimal searching behaviour generated intrinsically by the central pattern generator for locomotion

Jimena Berni, David W. Sims & Nicolas E. Humphries
Efficient searching for resources such as food by animals is key to their survival. It has been proposed that diverse animals from insects to sharks and humans adopt searching patterns that resemble a simple Lévy random walk, which is theoretically optimal for ‘blind foragers’ to locate sparse, patchy resources. To test if such patterns are generated intrinsically, or arise via environmental interactions, we tracked free-moving Drosophila larvae with (and without) blocked synaptic activity in the...

Data from: Evolution transforms pushed waves into pulled waves

Philip Erm & Ben Phillips
Understanding the dynamics of biological invasions is crucial for managing numerous phenomena, from invasive species to tumours. While the Allee effect (where individuals in low-density populations suffer lowered fitness) is known to influence both the ecological and evolutionary dynamics of an invasion, the possibility that an invader's susceptibility to the Allee effect might itself evolve has received little attention. Since invasion fronts are regions of perpetually low population density, selection should be expected to favour...

Data from: Consistent within‐individual plasticity is sufficient to explain temperature responses in red deer reproductive traits

Hannah Froy, Julien Martin, Katie Stopher, Alison Morris, Sean Morris, Tim Clutton-Brock, Josephine Pemberton & Loeske Kruuk
Warming global temperatures are affecting a range of aspects of wild populations, but the exact mechanisms driving associations between temperature and phenotypic traits may be difficult to identify. Here, we use a 36‐year data set on a wild population of red deer to investigate the causes of associations between temperature and two important components of female reproduction: timing of breeding and offspring size. By separating within‐ versus between‐individual associations with temperature for each trait, we...

Collective decision-making appears more egalitarian in populations where group fission costs are higher

James Herbert-Read, Amy Wade, Indar Ramnarine & Christos Ioannou
Collective decision-making is predicted to be more egalitarian in conditions where the costs of group fission are higher. Here we ask whether Trinidadian guppies (Poecilia reticulata) living in high or low predation environments, and thereby facing differential group fission costs, make collective decisions in line with this prediction. Using a classic decision-making scenario, we found that fish from high predation environments switched their positions within groups more frequently than fish from low predation environments. Because...

Data from: The yeast mitochondrial pyruvate carrier is a hetero-dimer in its functional state

Sotiria Tavoulari, Chancievan Thangaratnarajah, Vasiliki Mavridou, Michael E. Harbour, Jean-Claude Martinou & Edmund R.S. Kunji
The mitochondrial pyruvate carrier (MPC) is critical for cellular homeostasis, as it is required in central metabolism for transporting pyruvate from the cytosol into the mitochondrial matrix. MPC has been implicated in many diseases and is being investigated as a drug target. A few years ago, small membrane proteins, called MPC1 and MPC2 in mammals and Mpc1, Mpc2 and Mpc3 in yeast, were proposed to form large protein complexes responsible for this function. However, the...

Data from: Conflict within species determines the value of a mutualism between species

Syuan-Jyun Sun, Nicholas P.C. Horrocks & Rebecca M. Kilner
Mutually beneficial interactions between species play a key role in maintaining biodiversity and ecosystem function. Nevertheless, such mutualisms can erode into antagonistic interactions. One explanation is that the fitness costs and benefits of interacting with a partner species vary among individuals. However, it is unclear why such variation exists. Here we demonstrate that social behaviour within species plays an important, though hitherto overlooked, role in determining the relative fitness to be gained from interacting with...

Data from: Inbreeding alters context‐dependent reproductive effort and immunity in male crickets

Kristin R. Duffield, Kylie J. Hampton, Thomas M. Houslay, John Hunt, Ben M. Sadd & Scott K. Sakaluk
Infection can cause hosts to drastically alter their investment in key life‐history traits of reproduction and defence. Infected individuals are expected to increase investment in defence (e.g., by increasing immune function) and, due to trade‐offs, investment in other traits (e.g., current reproduction) should decrease. However, the terminal investment hypothesis postulates that decreased lifespan due to infection and the associated reduction in the expectation for future offspring will favour increased investment towards current reproduction. Variation in...

Data from: Does evolutionary history correlate with contemporary extinction risk by influencing range size dynamics?

Andrew J. Tanentzap, Javier Igea, Matthew G. Johnston & Matthew J. Larcombe
Extinction threatens many species, yet is predicted by few factors across the plant Tree of Life (ToL). Taxon age is one factor that may associate with extinction if occupancy of geographic and adaptive zones varies with time, but evidence for such an association has been equivocal. Age-dependent occupancy can also influence diversification rates and thus extinction risk where new taxa have small range and population sizes. To test how age, diversification, and range size were...

Temporal Human Pressure Index

Jonas Geldmann, Lucas Joppa & Neil D. Burgess
It is widely accepted that the main driver of the observed decline in biological diversity is increasing human pressure on Earth’s ecosystems. However, the spatial patterns of change in human pressure and their relation to conservation efforts are less well known. We developed a spatially and temporally explicit map of global change in human pressure over two decades between 1990 and 2010 at a resolution of 10 km2. We evaluated 22 spatial data sets representing...

Dielectric induced surface wave radiation loss

Tobias Schaich, Trevor Morsman, Anas Al Rawi & Mike Payne
Data and source code for the article "Dielectric Induced Surface Wave Radiation Loss" submitted to the Proceedings of the Royal Society A.

Assessing the potential for indirect interactions between tropical tree species via shared insect seed predators

Harriet Downey, Owen T. Lewis, Michael B. Bonsall, Alan Ward & Sofia Gripenberg.
Natural enemies of plants have the potential to influence the dynamics of plant populations and the structure of plant communities. In diverse tropical forests research on the effects of plant enemies has largely focused on the diversity-enhancing effects of highly specialised enemies, while the community-level effects of enemies with broader diets have rarely been considered. We investigated the community of insect seed predators interacting with seven tree species in the family Lauraceae on Barro Colorado...

Quantifying the structure and dynamics of fish shoals under predation threat in three-dimensions

Maksym Romenskyy, James Herbert-Read, Christol Ioannou, Alex Szorkovszky, Ashley Ward & David Sumpter
Detailed quantifications of how predators and their grouping prey interact in three dimensions (3D) remain rare. Here we record the structure and dynamics of fish shoals (Pseudomugil signifer) in 3D both with and without live predators (Philypnodon grandiceps) under controlled laboratory conditions. Shoals adopted two distinct types of shoal structure; ‘sphere-like’ geometries at depth, and flat ‘carpet-like’ structures at the water’s surface, with shoals becoming more compact in both horizontal and vertical planes in the...

Data from: Comparative phylogeography of three host sea anemones in the Indo-Pacific

Pablo Saenz-Agudelo, Madeleine Emms, Emily Giles, Remy Gatins, Gerrit Nanninga, Anna Scott, Jean Paul Hobbs, Ashley Frisch, Suzanne Mills, Ricardo Beldade & Michael Berumen
Aim The mutualistic relationship between anemones and anemonefishes is one of the most iconic examples of symbiosis. However, while anemonefishes have been extensively studied in terms of genetic connectivity, such information is lacking entirely for host sea anemones. Here, we provide the first information on the broad-scale population structure and phylogeographic patterns of three species of host sea anemone, Heteractis magnifica, Stichodactyla mertensii, and Entacmaea quadricolor. We evaluate if there is concordance in genetic structure...

Data from: Release from intralocus sexual conflict? Evolved loss of a male sexual trait demasculinises female gene expression

Jack G. Rayner, Sonia Pascoal & Nathan W. Bailey
The loss of sexual ornaments is observed across taxa, and pleiotropic effects of such losses provide an opportunity to gain insight into underlying dynamics of sex-biased gene expression and intralocus sexual conflict (IASC). We investigated this in a Hawaiian field cricket, Teleogryllus oceanicus, in which an X-linked genotype (flatwing) feminises males’ wings and eliminates their ability to produce sexually selected songs. We profiled adult gene expression across somatic and reproductive tissues of both sexes. Despite...

Data from: Recombination rate variation shapes barriers to introgression across butterfly genomes

Simon H. Martin, John W. Davey, Camilo Salazar & Chris D. Jiggins
Hybridisation and introgression can dramatically alter the relationships among groups of species, leading to phylogenetic discordance across the genome and between populations. Introgression can also erode species differences over time, but selection against introgression at certain loci acts to maintain post-mating species barriers. Theory predicts that species barriers made up of many loci throughout the genome should lead to a broad correlation between introgression and recombination rate, which determines the extent to which selection on...

Data from: Decreased brain connectivity in smoking contrasts with increased connectivity in drinking

Wei Cheng, Edmund T. Rolls, Trevor W. Robbins, Weikang Gong, Zhaowen Liu, Wujun Lv, Jingnan Du, Hongkai Wen, Liang Ma, Erin Burke Quinlan, Hugh Garavan, Eric Artiges, Dimitri Papadopoulos Orfanos, Michael N. Smolka, Gunter Schumann, Keith Kendrick & Jianfeng Feng
In a group of 831 participants from the general population in the Human Connectome Project, smokers exhibited low overall functional connectivity, and more specifically of the lateral orbitofrontal cortex which is associated with non-reward mechanisms, the adjacent inferior frontal gyrus, and the precuneus. Participants who drank a high amount had overall increases in resting state functional connectivity, and specific increases in reward-related systems including the medial orbitofrontal cortex and the cingulate cortex. Increased impulsivity was...

Data from: A Western route of prehistoric human migration from Africa into the Iberian Peninsula

Gloria Gonzalez-Fortes, Francesca Tassi, Emiliano Trucchi, Kirstin Henneberger, Johanna L.A. Paijmans, Daviz Diez-Del-Molino, Hannes Schroeder, Cecilio Barroso, Francisco J. Bermudez, Cecilio Barroso-Medina, Ana M.S. Bettencourt, Hugo A. Sampaio, Aurora Grandal-D'Anglade, Antonio Salas, Arturo De Lombera-Hermida, Ramon Fabregas, Manuel Vaquero, Susana Alonso, Maria Lozano, Xavier Rodríguez-Alvarez, Carlos Fernández-Rodríguez, Andrea Manica, Michael Hofreiter & Guido Barbujani
Being at the Western fringe of Europe, Iberia had a peculiar prehistory and a complex pattern of Neolithization. A few studies, all based on modern populations, reported the presence of DNA of likely African origin in this region, generally concluding it was the result of recent gene flow, probably during the Islamic period. Here we provide evidence of much older gene flow from Africa to Iberia by sequencing whole genomes from four human remains from...

Effects of BCG vaccination against Bovine Tuberculosis: a systematic review and meta-analysis Date

V. Srikrishnan, A. Conlan, L. Easterling, C. Herrara, P. Dandapat, M. Veerasami, G. Ameni, D. Bakker, M. Vordermeier & V. Kapur
Despite the effective control of Bovine Tuberculosis (bTB) in many countries using test-and-slaughter, more than 50 million cattle are still likely to be infected worldwide, highlighting the urgent need for alternative interventions such as vaccines to reduce disease burden and control spread of bTB. Vaccination may be particularly important in regions where the disease is endemic, and test-and-slaughter is neither practical nor acceptable socio-economically. Bacillus Calmette-Guérin (BCG) has been in experimental use in cattle for...

Polysome fractionation analysis reveals features important for human nonsense-mediated mRNA decay

James Lloyd, Courtney French & Steven Brenner
Nonsense-mediated mRNA decay (NMD) is a translation-dependent mRNA surveillance pathway that eliminates transcripts with premature termination codons. Several studies have tried defined the features governing which transcripts are targeted to NMD. However, these approaches often rely on inhibiting core NMD factors, which often have roles in non-NMD processes within the cell. Based on reports that NMD-targeted transcripts are often bound by a single ribosome, we analyzed RNA-Seq data from a polysome fractionation experiment (TrIP-Seq) to...

Data from: Hyperandrogenism and insulin resistance induce gravid uterine defects in association with mitochondrial dysfunction and aberrant ROS production

Min Hu, Yuehui Zhang, Xiaozhu Guo, Wenyan Jia, Guoqi Liu, Jiao Zhang, Juan Li, Peng Cui, Amanda N. Sferruzzi-Perrie, Yanhua Han, Xiaoke Wu, Hongxia Ma, Mats Brännström, Linus R. Shao & Håkan Billig
Women with polycystic ovary syndrome (PCOS) are at increased risk of miscarriage, which often accompanies the hyperandrogenism and insulin resistance seen in these patients. However, neither the combinatorial interaction between these two PCOS-related etiological factors nor the mechanisms of their actions in the uterus during pregnancy are well understood. We hypothesised that hyperandrogensim and insulin resistance exert a causative role in miscarriage by inducing defects in uterine function that are accompanied by mitochondrial-mediated oxidative stress,...

Data from: Seasonal variation in food availability and relative importance of dietary items in the Gambian epauletted fruit bat (Epomophorus gambianus)

Kofi Amponsah-Mensah, Andrew A. Cunningham, James L.N. Wood & Yaa Ntiamoa-Baidu
1. The Gambian epauletted fruit bat (Epomophorus gambianus) is very common across a variety of West African habitats, but very little information is available on its feeding ecology or its contribution to ecosystem function. 2. We investigated seasonal variation in food availability and the relative importance of dietary items used by this species in a forest-savannah transitional ecosystem. Dietary items were identified from 1,470 samples of faecal and ejecta pellets which had been collected under...

Data from: Genetic diversity, demographic history and neo-sex chromosomes in the Critically Endangered Raso lark

Elisa G. Dierickx, Simon Yung Wa Sin, Pieter Van Veelen, M. De L. Brooke, Yang Liu, Scott V. Edwards & Simon H. Martin
Small effective population sizes could expose island species to inbreeding and loss of genetic variation. Here, we investigate factors shaping genetic diversity in the Raso lark, which has been restricted to a single islet for approximately 500 years, with a population size of a few hundred. We assembled a reference genome for the related Eurasian skylark and then assessed diversity and demographic history using RAD-seq data (75 samples from Raso larks and two related mainland...

Registration Year

  • 2019
    58

Resource Types

  • Dataset
    56
  • Collection
    2

Affiliations

  • University of Cambridge
    58
  • University of Edinburgh
    3
  • Plymouth University
    2
  • University of Vermont
    2
  • University of Aberdeen
    2
  • University of Otago
    2
  • King's College London
    2
  • University of East Anglia
    2
  • University of Zurich
    2
  • Griffith University
    2