15 Works

Data from: Phosphorescence monitoring of hypoxic microenvironment in solid-tumors to evaluate chemotherapeutic effects using the hypoxia-sensitive iridium (III) coordination compound

Yun Zeng, Yang Liu, Jin Shang, Jingwen Ma, Rong Wang, Lei Deng, Youmin Guo, Fan Zhong, Mingfeng Bai, Shaojuan Zhang & Daocheng Wu
Objectives: To utilize phosphorescence to monitor hypoxic microenvironment in solid-tumors and investigate cancer chemotherapeutic effects in vivo. Methods: A hypoxia-sensitive probe named BTP was used to monitor hypoxic microenvironment in solid-tumors. The low-dose metronomic treatment with cisplatin was used in anti-angiogenetic chemotherapeutic programs. The phosphorescence properties of BTP were detected by a spectrofluorometer. BTP cytotoxicity utilized cell necrosis and apoptosis, which were evaluated by trypan blue dye exclusion and Hoechst33342 plus propidium iodide assays. Tumor-bearing...

Data from: Population structure of a microparasite infecting Daphnia: spatio-temporal dynamics

, , , , &
Background: Detailed knowledge of spatial and temporal variation in the genetic population structure of hosts and parasites is required for understanding of hostparasite coevolution. As hot-spots of contemporary coevolution in natural systems are difficult to detect and long-term studies are restricted to few systems additional population genetic data from various hostparasite systems may provide important insights into the topic. This is particularly true for parasites as these players have been under-investigated so far due to...

Data from: Comparison of solar-induced chlorophyll fluorescence, light-use efficiency, and process-based GPP models in maize

Pradeep Wagle, Yongguang Zhang, Cui Jin & Xiangming Xiao
Accurately quantifying cropland gross primary production (GPP) is of great importance to monitor cropland status and carbon budgets. Satellite-based light-use efficiency (LUE) models and process-based terrestrial biosphere models (TBMs) have been widely used to quantify cropland GPP at different scales in past decades. However, model estimates of GPP are still subject to large uncertainties, especially for croplands. More recently, space-borne solar-induced chlorophyll fluorescence (SIF) has shown the ability to monitor photosynthesis from space, providing new...

Data from: Co-expression of two subtypes of melatonin receptor on rat M1-type intrinsically photosensitive retinal ganglion cells

Wen-Long Sheng, Wei-Yi Chen, Xiong-Li Yang, Yong-Mei Zhong & Shi-Jun Weng
Intrinsically photosensitive retinal ganglion cells (ipRGCs) are involved in circadian and other non-image forming visual responses. An open question is whether the activity of these neurons may also be under the regulation mediated by the neurohormone melatonin. In the present work, by double-staining immunohistochemical technique, we studied the expression of MT1 and MT2, two known subtypes of mammalian melatonin receptors, in rat ipRGCs. A single subset of retinal ganglion cells labeled by the specific antibody...

Data from: Extreme environments facilitate hybrid superiority - the story of a successful Daphnia galeata × longispina hybrid clone

Johanna Griebel, Sabine Gießler, Monika Poxleitner, Amanda Navas Faria, Mingbo Yin & Justyna Wolinska
Hybridization within the animal kingdom has long been underestimated. Hybrids have often been considered less fit than their parental species. In the present study, we observed that the Daphnia community of a small lake was dominated by a single D. galeata × D. longispina hybrid clone, during two consecutive years. Notably, in artificial community set-ups consisting of several clones representing parental species and other hybrids, this hybrid clone took over within about ten generations. Neither...

Data from: Intra- and intersession repeatability of an optical quality and intraocular scattering measurement system in children

Mi Tian, Huamao Miao, Yang Shen, Jian Gao, Xiaofen Mo & Xingtao Zhou
Purpose: To evaluate intra- and intersession repeatability of objective optical quality and intraocular scattering measurements with a double-pass system in children. Methods: Forty-two eyes of 42 children were included in the study. An optical quality analysis system (OQAS) was used to measure optical quality parameters, including modulation transfer function cutoff frequency (MTFcutoff), Strehl ratio (SR), OQAS values (OV) at 3 different contrasts and objective scatter index (OSI). Three measurement sessions with 10-min intervals were operated...

Data from: Upregulation of NLRP3 inflammasome in the tears and ocular surface of dry eye patients

Liangliang Niu, Shujie Zhang, Jihong Wu, Ling Chen & Yan Wang
Purpose: To evaluate the mRNA and protein expressions of NLRP3 inflammasome and its downstream inflammatory factors in human dry eye. Methods: We recruited 54 patients with Sjögren’s syndrome dry eye (SSDE), 50 patients with non-Sjögren’s syndrome dry eye (NSSDE), and 46 healthy controls. Tear film breakup time (TBUT), Schirmer I test, and fluorescein staining (FL) were performed on all subjects. Tear samples were obtained to analyze the inflammatory cytokine levels of IL-1β and IL-18 via...

Data from: Trophic dynamics of filter feeding bivalves in the Yangtze Estuarine Intertidal Marsh: stable isotope and fatty acid analyses

Sikai Wang, Binsong Jin, Haiming Qin, Qiang Sheng & Jihua Wu
Benthic bivalves are important links between primary production and consumers, and are essential intermediates in the flow of energy through estuarine systems. However, information on the diet of filter feeding bivalves in estuarine ecosystems is uncertain, as estuarine waters contain particulate matter from a range of sources and as bivalves are opportunistic feeders. We surveyed bivalves at different distances from the creek mouth at the Yangtze estuarine marsh in winter and summer, and analyzed trophic...

Data from: The association of outdoor activity and age-related cataract in a rural population of Taizhou Eye Study: phase 1 report

Yating Tang, Yinghong Ji, Xiaofang Ye, Xiaofeng Wang, Lei Cai, Jianming Xu & Yi Lu
Purpose: To study the relationship between outdoor activity and risk of age-related cataract (ARC) in a rural population of Taizhou Eye Study (phrase 1 report). Method: A population-based, cross-sectional study of 2006 eligible rural adults (≥45 years old) from Taizhou Eye Study was conducted from Jul. to Sep. 2012. Participants underwent detailed ophthalmologic examinations including uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), intraocular pressure (IOP), slit lamp and fundus examinations as well as...

Data from: Genetic structure of Daphnia galeata populations in Eastern China

Wenzhi Wei, Sabine Gießler, Justyna Wolinska, Xiaolin Ma, Zhong Yang, Wei Hu & Mingbo Yin
This study presents the first examination of the genetic structure of Daphnia longispina complex populations in Eastern China. Only one species, D. galeata, was present across the eight investigated lakes; as identified by taxon assignment using allelic variation at 15 microsatellite loci. Three genetically differentiated D. galeata subgroups emerged independent of the type of statistical analysis applied. Thus, Bayesian clustering, discriminant analysis based on results from factorial correspondence analysis, and UPGMA clustering consistently showed that...

Data from: Simultaneous declines in summer survival of three shorebird species signals a flyway at risk

Theunis Piersma, Tamar Lok, Ying Chen, Chris J. Hassell, Hong-Yan Yang, Adrian Boyle, Matt Slaymaker, Ying-Chi Chan, David S. Melville, Zheng-Wang Zhang & Zhijun Ma
There is increasing concern about the world's animal migrations. With many land-use and climatological changes occurring simultaneously, pinning down the causes of large-scale conservation problems requires sophisticated and data-intensive approaches. Declining shorebird numbers along the East Asian–Australasian Flyway, in combination with data on habitat loss along the Yellow Sea (where these birds refuel during long-distance migrations), indicate a flyway under threat. If habitat loss at staging areas indeed leads to flyway-wide bird losses, we would...

Data from: Axial myopia is associated with visual field prognosis of primary open-angle glaucoma

Chen Qiu, Shaohong Qian, Xinghuai Sun, Chuandi Zhou & Fanrong Meng
Purpose: To identify whether myopia was associated with the visual field (VF) progression of primary open-angle glaucoma (POAG). Methods: A total of 270 eyes of 270 POAG followed up for more than 3 years with ≥9 reliable VFs by Octopus perimetry were retrospectively reviewed. Myopia was divided into: mild myopia (-2.99 diopter [D], 0), moderate myopia (-5.99, 3.00 D), marked myopia (-9.00, -6.00 D) and non-myopia (0 D or more). An annual change in the...

Data from: Health-related lifestyle behaviors among male and female rural-to-urban migrant workers in Shanghai, China

Hua Yang, Fang He, Tianhao Wang, Yao Liu, Yao Shen, Jian Gong, Wei Dai, Jing Zhou, Jie Gu, Yimin Tu, Tianying Wang, Lei Shen, Yumiao Wu, Xiuping Xia, Donghao Xu, Zhigang Pan & Shanzhu Zhu
Background: Lifestyle behaviors significantly impact health, yet remain poorly defined in Chinese rural-to-urban migrants. Methods: In a cross-sectional study of health-related behaviors of 5484 rural-to-urban migrants who had worked in Shanghai for at least six months, we assessed the contribution of demographics and physical and mental health to lifestyle behaviors in male and female participants by multiple stepwise cumulative odds logistic regression. Results: Respondents were 51.3% male. 9.9% exhibited abnormal blood pressure; 27.0% were overweight...

Data from: Long-term visual outcomes of secondary intraocular lens implantation in children with congenital cataract

Xianfang Rong, Yinghong Ji, Yanwen Fang, Yongxiang Jiang & Yi Lu
Aim: The aim of this study was to evaluate the long-term visual outcomes and factors affecting visual results in children undergoing secondary intraocular lens (IOL) implantation following primary congenital cataract extraction. Methods: Children with congenital cataracts who underwent secondary IOL implantation for aphakia at the Eye and ENT Hospital of Fudan University between January 1, 2001, and December 31, 2007, were retrospectively reviewed. One eye was randomly selected in children with bilateral cataracts. Laterality, type...

Data from: Specialist insect herbivore and light availability do not interact in the evolution of an invasive plant

Zhijie Zhang, Xiaoyun Pan, Ziyan Zhang, Kate S. He & Bo Li
Release from specialist insect herbivores may allow invasive plants to evolve traits associated with decreased resistance and increased competitive ability. Given that there may be genetic trade-off between resistance and tolerance, invasive plants could also become more tolerant to herbivores. Although it is widely acknowledged that light availability affects tolerance to herbivores, little information is available for whether the effect of light availability on tolerance differ between the introduced and native populations. We conducted a...

Registration Year

  • 2015

Resource Types

  • Dataset


  • Fudan University
  • Leibniz Institute of Freshwater Ecology and Inland Fisheries
  • Ludwig Maximilian University of Munich
  • Centre d'Ecologie Fonctionnelle et Evolutive
  • University of Groningen
  • Xi'an Jiaotong University
  • University of Pittsburgh
  • Murray State University
  • Royal Netherlands Institute for Sea Research
  • Nanjing University