3 Works

Alterations in mitochondrial respiratory capacity and membrane potential: a link between mitochondrial dysregulation and autism

, , , &
Mitochondrial dysfunction has been implicated in the pathogenesis of autism. We compared mitochondrial respiratory control in autism with normal lymphoblastoid cell line and found that the oxidative phosphorylation and electron transfer of the NADH- and succinate-linked pathways, and cytochrome c oxidase activity of the autism lymphoblastoid cell line were higher. Mitochondrial membrane potential was also higher in the succinate-pathway during LEAK respiration and oxidative phosphorylation. Taken together, these results indicate abnormalities in mitochondrial function with...

Probiotic-prebiotic therapy improved constipation and gut motility in Parkinson’s disease: Randomised controlled trial

Norlinah Mohamed Ibrahim, Raja Affendi Raja Ali, Mohd Rizal Abdul Manaf, Norfazilah Ahmad, Farah Waheeda Tajurruddin, Zhi Qin Wong, Azliza Ibrahim &
Objective: We determined the effectiveness of a multi-strain probiotic-prebiotic combination on constipation symptoms and gut motility in PD patients with constipation. Methods: PD patients with constipation (ROME III criteria) were randomized to receive a multi-strain probiotic (Lactobacillus sp and Bifidobacterium sp at 30 X 109 CFU) with fructo-oligosaccaride (prebiotic) or placebo (fermented milk) twice daily for 8 weeks. Primary outcomes were changes in the presence of constipation symptoms using 9 items of Garrigues Questionnaire (GQ),...

Factors associated with patient satisfaction towards pharmacy services among out-patients attending public health clinics: Questionnaire development and its application

Norfazilah Ahmad, Aniza Ismail & Yan Nee Gan
Introduction: Patient satisfaction is widely used to measure quality of healthcare by identifying potential areas for improvement. Aim of study is to assess patient satisfaction towards pharmacy services and its associated factors using newly developed questionnaire among outpatients attending public health clinics. Materials and Methods: Public Health Clinic Patient Satisfaction Questionnaire (PHC-PSQ) towards pharmacy services was developed using exploratory factor analysis and Cronbach’s α. A cross-sectional study was conducted among 400 patients visiting the pharmacy...

Registration Year

  • 2020
    3

Resource Types

  • Dataset
    2
  • Data Paper
    1

Affiliations

  • University Kebangsaan Malaysia Medical Centre
    3
  • Ministry of Health
    1
  • Innsbruck Medical University
    1