163 Works

Data from: Advancing Precambrian palaeomagnetism with the PALEOMAGIA and PINT(QPI) databases

Toni H. Veikkolainen, Andrew J. Biggin, Lauri J. Pesonen, David A. Evans & Nicholas A. Jarboe
State-of-the-art measurements of the direction and intensity of Earth’s ancient magnetic field have made important contributions to our understanding of the geology and palaeogeography of Precambrian Earth. The PALEOMAGIA and PINT(QPI) databases provide thorough public collections of important palaeomagnetic data of this kind. They comprise more than 4,100 observations in total and have been essential in supporting our international collaborative efforts to understand Earth's magnetic history on a timescale far longer than that of the...

Data from: Destabilizing mutations encode nongenetic variation that drives evolutionary innovation

Katherine L. Petrie, Nathan D. Palmer, Daniel T. Johnson, Sarah J. Medina, Stephanie J. Yan, Victor Li, Alita R. Burmeister & Justin R. Meyer
Evolutionary innovations are often achieved by repurposing existing genes to perform new functions; however, the mechanisms enabling the transition from old to new remain controversial. We identified mutations in bacteriophage λ’s host-recognition gene J that confer enhanced adsorption to λ’s native receptor, LamB, and the ability to access a new receptor, OmpF. The mutations destabilize particles and cause conformational bistability of J, which yields progeny of multiple phenotypic forms, each proficient at different receptors. This...

Data from: Comparative dynamics of microglialand glioma cell motility at the infiltrative margin of brain tumours

Joseph Juliano, Orlando Gil, Andrea Hawkins-Daarud, Sonal Noticewala, Russell C. Rockne, Jill Gallaher, Susan C. Massey, Peter A. Sims, Alexander R. A. Anderson, Kristin R. Swanson & Peter Canoll
Microglia are a major cellular component of gliomas, and abundant in the centre of the tumour and at the infiltrative margins. While glioma is a notoriously infiltrative disease, the dynamics of microglia and glioma migratory patterns have not been well characterized. To investigate the migratory behaviour of microglia and glioma cells at the infiltrative edge, we performed two-colour time-lapse fluorescence microscopy of brain slices generated from a platelet-derived growth factor-B (PDGFB)-driven rat model of glioma,...

Data from: Multi-behavioral endpoint testing of an 87-chemical compound library in freshwater planarians

Siqi Zhang, Danielle Hagstrom, Patrick Hayes, Aaron Graham & Eva-Maria S. Collins
There is an increased recognition in the field of toxicology of the value of medium-to-high-throughput screening methods using in vitro and alternative animal models. We have previously introduced the asexual freshwater planarian Dugesia japonica as a new alternative animal model and proposed that it is particularly well-suited for the study of developmental neurotoxicology. In this paper, we discuss how we have expanded and automated our screening methodology to allow for fast screening of multiple behavioral...

Data from: Bees eavesdrop upon informative and persistent signal compounds in alarm pheromones

Zhengwei Wang, Ping Wen, Yufeng Qu, Shihao Dong, Jianjun Li, Ken Tan & James C. Nieh
Pollinators such as bees provide a critical ecosystem service that can be impaired by information about predation. We provide the first evidence for olfactory eavesdropping and avoidance of heterospecific alarm signals, alarm pheromones, at food sources in bees. We predicted that foragers would eavesdrop upon heterospecific alarm pheromones, and would detect and avoid conspicuous individual pheromone compounds, defined by abundance and how long they can linger to provide warning information (volatility). We show that Apis...

Data from: CO2-induced ocean acidification does not affect individual or group behaviour in a temperate damselfish

Garfield Tsz Kwan, Trevor James Hamilton & Martin Tresguerres
Open ocean surface CO2 levels are projected to reach approximately 800 µatm, and ocean pH to decrease by approximately 0.3 units by the year 2100 due to anthropogenic CO2 emissions and the subsequent process of ocean acidification (OA). When exposed to these CO2/pH values, several fish species display abnormal behaviour in laboratory tests, an effect proposed to be linked to altered neuronal GABAA­ receptor function. Juvenile blacksmith (Chromis punctipinnis) are social fish that regularly experience...

Data from: Testing the effects of ant invasions on non-ant arthropods with high-resolution taxonomic data

Cause Hanna, Ida Naughton, Christina Boser & David Holway
Invasions give rise to a wide range of ecological effects. Many invasions proceed without noticeable impacts on the resident biota, whereas others shift species composition and even alter ecosystem function. Ant invasions generate a broad spectrum of ecological effects, but controversy surrounds the extent of these impacts, especially with regard to how other arthropods are affected. This uncertainty in part results from the widespread use of low-resolution taxonomic data, which can mask the presence of...

Data from: Physiological, morphological, and ecological tradeoffs influence vertical habitat use of deep-diving toothed-whales in the Bahamas

Trevor W. Joyce, John W. Durban, Diane E. Claridge, Charlotte A. Dunn, Holly Fearnbach, Kim M. Parsons, Russel D. Andrews & Lisa T. Ballance
Dive capacity among toothed whales (suborder: Odontoceti) has been shown to generally increase with body mass in a relationship closely linked to the allometric scaling of metabolic rates. However, two odontocete species tagged in this study, the Blainville’s beaked whale Mesoplodon densirostris and the Cuvier’s beaked whale Ziphius cavirostris, confounded expectations of a simple allometric relationship, with exceptionally long (mean: 46.1 min & 65.4 min) and deep dives (mean: 1129 m & 1179 m), and...

Data from: Deep neural networks for accurate predictions of crystal stability

Weike Ye, Chi Chen, Zhenbin Wang, Iek-Heng Chu & Shyue Ping Ong
Predicting the stability of crystals is one of the central problems in materials science. Today, density functional theory (DFT) calculations remain comparatively expensive and scale poorly with system size. Here we show that deep neural networks utilizing just two descriptors—the Pauling electronegativity and ionic radii—can predict the DFT formation energies of C3A2D3O12 garnets and ABO3 perovskites with low mean absolute errors (MAEs) of 7–10 meV atom−1 and 20–34 meV atom−1, respectively, well within the limits...

Impact of Helicoverpa zea salivary GOX on stomatal conductance and volatile emission of host plants

Po-An Lin, Yintong Chen, Duverney Chaverra-Rodriguez, Chan Chin Heu, Nursyafiqi Bin Zainuddin, Jagdeep Singh Sidhu, Michelle Peiffer, Ching-Wen Tan, Anjel Helms, Donghun Kim, Jared Ali, Jason Rasgon, Jonathan Lynch, Charles Anderson & Gary Felton
This data set contain raw data associated with the manuscript titled "Silencing the alarm: An insect salivary enzyme closes plant stomata and inhibits volatile release". Herbivore-induced plant volatiles (HIPVs) are widely recognized as ecologically important to plant. While the majority of studies focused on the induction of this “cry for help”, little is known about whether insect herbivores have evolved mechanisms to reduce the release of HIPVs. Here we show that a caterpillar (Helicoverpa zea)...

Gorilla herpes simplexvirus phylogenetic analysis

Joel Wertheim
Viruses closely related to human pathogens can reveal the origins of human infectious diseases. Human herpes simplexvirus type 1 (HSV-1) and type 2 (HSV-2) are hypothesized to have arisen via host-virus co-divergence and cross-species transmission. We report the discovery of novel herpes simplexviruses during a large-scale screening of fecal samples from wild gorillas, bonobos, and chimpanzees. Phylogenetic analysis indicates that, contrary to expectation, simplexviruses from these African apes are all more closely related to HSV-2...

Triennial migration and philopatry in the critically endangered soupfin shark (Galeorhinus galeus)

Andrew Nosal, Daniel Cartamil, Arnold Ammann, Lyall Bellquist, Noah Ben-Aderet, Kayla Blincow, Echelle Burns, Eric Chapman, Ryan Freedman, Peter Klimley, Ryan Logan, Christopher Lowe, Brice Semmens, Connor White & Philip Hastings
Globally, one-quarter of shark and ray species is threatened with extinction due to overfishing. Effective conservation and management can facilitate population recoveries; however, these efforts depend on robust data on movement patterns and stock structure, which are lacking for many threatened species, including the Critically Endangered soupfin shark (Galeorhinus galeus), a circumglobal coastal-pelagic species. Using passive acoustic telemetry, we continuously tracked 34 mature female soupfin sharks, surgically implanted with coded acoustic transmitters, for seven years...

Data from: Anticholinergic medications: A potentially modifiable risk factor for development of MCI

Alexandra Weigand, Mark W. Bondi, Kelsey R. Thomas, Noll L Campbell, Douglas Galasko, David P. Salmon, Daniel Sewell, James B. Brewer, Howard H Feldman & Lisa Delano-Wood
Objective: To determine the cognitive consequences of anticholinergic medications (aCH) in cognitively normal older adults as well as interactive effects of genetic and cerebrospinal fluid (CSF) Alzheimer’s disease (AD) risk factors. Methods: 688 cognitively normal participants from the Alzheimer’s Disease Neuroimaging Initiative were evaluated (mean age = 73.5, 49.6% female). Cox regression examined risk of progression to mild cognitive impairment (MCI) over a 10-year period, and linear mixed effects models examined 3-year rates of decline...

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  • University of California, San Diego
  • University of Kentucky
  • Yale University
  • Scripps Institution of Oceanography
  • University of California, Santa Barbara
  • Columbia University
  • University of Minnesota
  • Southwest Fisheries Science Center
  • University of Toronto
  • University of British Columbia