Data from: Diffusion tensor imaging reveals diffuse white matter injuries in locked-in syndrome patients

Mylène L. Leonard, Felix R. Renard, Laura H. Harsan, Julien P. Pottecher, Marc B. Braun, Francis S. Schneider, Pierre F. Froehlig, Frédéric B. Blanc, Daniel R. Roquet, Sophie A. Achard, Nicolas M. Meyer & Stéphane K. Kremer
Locked-in syndrome (LIS) is a state of quadriplegia and anarthria with preserved consciousness, which is generally triggered by a disruption of specific white matter fiber tracts, following a lesion in the ventral part of the pons. However, the impact of focal lesions on the whole brain white matter microstructure and structural connectivity pathways remains unknown. We used diffusion tensor magnetic resonance imaging (DT-MRI) and tract-based statistics to characterise the whole white matter tracts in seven...

Registration Year

  • 2019
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Resource Types

  • Dataset
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Affiliations

  • University of Strasbourg
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  • Centre Hospitalier Universitaire de Nancy
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  • French National Centre for Scientific Research
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  • Inserm
    1
  • Hôpitaux Universitaires de Strasbourg
    1