7 Works

Data from: Electricity and water conservation on college and university campuses in response to national competitions among dormitories: quantifying relationships between behavior, conservation strategies and psychological metrics

John E. Petersen, Cynthia M. Frantz, , Tess M. Yanisch, Evan Tincknell & Noel Myers
“Campus Conservation Nationals” (CCN) is a recurring, nation-wide electricity and water-use reduction competition among dormitories on college campuses. We conducted a two year empirical study of the competition’s effects on resource consumption and the relationship between conservation, use of web technology and various psychological measures. Significant reductions in electricity and water use occurred during the two CCN competitions examined (n = 105,000 and 197,000 participating dorm residents respectively). In 2010, overall reductions during the competition...

Data from: Assessing the potential information content of multicomponent visual signals: a machine learning approach

William L. Allen & James P. Higham
Careful investigation of the form of animal signals can offer novel insights into their function. Here, we deconstruct the face patterns of a tribe of primates, the guenons (Cercopithecini), and examine the information that is potentially available in the perceptual dimensions of their multicomponent displays. Using standardized colour-calibrated images of guenon faces, we measure variation in appearance both within and between species. Overall face pattern was quantified using the computer vision ‘eigenface’ technique, and eyebrow...

Data from: Whole genome resequencing reveals extensive natural variation in the model green alga Chlamydomonas reinhardtii

Jonathan M. Flowers, Khaled M. Hazzouri, Gina M. Pham, Ulises Rosas, Tayebeh Bahmani, Basel Khraiwesh, David R. Nelson, Kenan Jijakli, Rasha Abdrabu, Elizabeth H. Harris, Paul A. Lefebvre, Erik F. Y. Hom, Kourosh Salehi-Ashtiani & Michael D. Purugganan
We performed whole-genome resequencing of 12 field isolates and eight commonly studied laboratory strains of the model organism Chlamydomonas reinhardtii to characterize genomic diversity and provide a resource for studies of natural variation. Our data support previous observations that Chlamydomonas is among the most diverse eukaryotic species. Nucleotide diversity is ∼3% and is geographically structured in North America with some evidence of admixture among sampling locales. Examination of predicted loss-of-function mutations in field isolates indicates...

Data from: Unified pre- and postsynaptic long-term plasticity enables reliable and flexible learning

Rui Ponte Costa, Robert C. Froemke, Per Jesper Sjöström & Mark C. W. Van Rossum
Although it is well known that long-term synaptic plasticity can be expressed both pre- and postsynaptically, the functional consequences of this arrangement have remained elusive. We show that spike-timing-dependent plasticity with both pre- and postsynaptic expression develops receptive fields with reduced variability and improved discriminability compared to postsynaptic plasticity alone. These long-term modifications in receptive field statistics match recent sensory perception experiments. Moreover, learning with this form of plasticity leaves a hidden postsynaptic memory trace...

Data from: The kinetochore prevents centromere-proximal crossover recombination during meiosis

Nadine Vincenten, Lisa-Marie Kuhl, Isabel Lam, Ashwini Oke, Alastair R. W. Kerr, Andreas Hochwagen, Jennifer C. Fung, Scott Keeney, Gerben Vader & Adèle L. Marston
During meiosis, crossover recombination is essential to link homologous chromosomes and drive 22 faithful chromosome segregation. Crossover recombination is non-random across the genome, 23 and centromere-proximal crossovers are associated with an increased risk of aneuploidy, 24 including Trisomy 21 in humans. Here, we identify the conserved Ctf19/CCAN kinetochore sub- 25 complex as a major factor that minimizes potentially deleterious centromere-proximal crossovers 26 in budding yeast. We uncover multi-layered suppression of pericentromeric recombination by the 27...

Data from: Wild worm embryogenesis harbors ubiquitous polygenic modifier variation

Annalise B. Paaby, Amelia G. White, David D. Riccardi, Kristin C. Gunsalus, Fabio Piano & Matthew V. Rockman
Embryogenesis is an essential and stereotypic process that nevertheless evolves among species. Its essentiality may favor the accumulation of cryptic genetic variation (CGV) that has no effect in the wild-type but that enhances or suppresses the effects of rare disruptions to gene function. Here, we adapted a classical modifier screen to interrogate the alleles segregating in natural populations of C. elegans: we induced gene knockdowns and used quantitative genetic methodology to examine how segregating variants...

Data from: Transcriptome dynamics of the stomatal lineage: birth, amplification, and termination of a self-renewing population

Jessika Adrian, Jessica Chang, Catherine E. Ballenger, Bastiaan O. R. Bargmann, Julien Alassimone, Kelli A. Davies, On Sun Lau, Juliana L. Matos, Charles Hachez, Amy Lanctot, Anne Vatén, Kenneth D. Birnbaum & Dominique C. Bergmann
Developmental transitions can be described in terms of morphology and the roles of individual genes, but also in terms of global transcriptional and epigenetic changes. Temporal dissections of transcriptome changes, however, are rare for intact, developing tissues. We used RNA sequencing and microarray platforms to quantify gene expression from labeled cells isolated by fluorescence-activated cell sorting to generate cell-type-specific transcriptomes during development of an adult stem-cell lineage in the Arabidopsis leaf. We show that regulatory...

Registration Year

  • 2015

Resource Types

  • Dataset


  • New York University
  • New York University Abu Dhabi
  • University of Edinburgh
  • Howard Hughes Medical Institute
  • Stanford University
  • Duke University
  • University of Minnesota
  • McGill University
  • Université Catholique de Louvain
  • Wellcome Trust