Additional file 4. Stacked histograms of time intervals between start of etanercept/adalimumab therapy and baseline/follow-up measurements.

Additional file 1: Score sheet for assessment of humane end point.

: Meningioma has a prevalence around 1% in the population and with the increasing use and availability of diagnostic imaging modalities incidental meningiomas are increasingly detected. There is no clear consensus on their management, although several guidelines suggest firsthand active monitoring if no aggravating factors emerge. However, no collective guidelines on follow-up interval exist. This narrative review covers the epidemiology, diagnosis, growth prediction and management strategies of incidental meningioma. : Overdiagnosis and excessive follow-up are...

Abstract Background Community-acquired pneumonia (CAP) is the most frequent infection diagnosis in hospitals. Antimicrobial therapy for CAP is depicted in clinical practice guidelines, but adherence data and effect of antibiotic stewardship measures are lacking. Methods A dedicated antibiotic team pointed out CAP as a potential target for antimicrobial stewardship (AMS) measures at a 1.000-bed, tertiary care, teaching university hospital in Norway from March until May for the years 2016 throughout 2021. The aim of the...

Supplemental material, sj-docx-1-tec-10.1177_17474930221126592 for Does implementation of a standardized pathway of stroke care affect functional outcome after stroke? by Elin Bergh, Torunn Askim, Ole Morten Rønning, Jurate Šaltyteė Benth, Hild Fjærtoft and Bente Thommessen in International Journal of Stroke

Supplemental material, sj-docx-2-tec-10.1177_17474930221126592 for Does implementation of a standardized pathway of stroke care affect functional outcome after stroke? by Elin Bergh, Torunn Askim, Ole Morten Rønning, Jurate Šaltyteė Benth, Hild Fjærtoft and Bente Thommessen in International Journal of Stroke

Background:A stroke care pathway (SCP) was introduced in Norway in 2018. The goal of the pathway was to avoid delay in treatment and diagnostics of acute stroke and to secure treatment according to national guidelines. In this study, we aimed to evaluate how the implementation of the SCP affects outcome after stroke.Methods:We performed a register-based study using data from the Norwegian Stroke Register that covers 87% of acute stroke patients in Norway. Patients included 1...

Supplemental data for JCEM.

Abstract Background Traditional observational studies have shown an inverse association between body mass index (BMI) and lung cancer risk. Mendelian randomization (MR) analysis using genetic variants as instruments for BMI may clarify the nature of the association. Aims We studied the causal association between BMI and lung cancer incidence using observational and MR approaches. Methods We followed up 62,453 cancer-free Norwegian adults from 1995–97 (HUNT2) until 2017. BMI at baseline in HUNT2 was classified as...

Rationale:The evidence base for acute post-stroke rehabilitation is inadequate and global guideline recommendations vary.Aim:To define optimal early mobility intervention regimens for ischemic stroke patients of mild and moderate severity.Hypotheses:Compared with a prespecified reference arm, the optimal dose regimen(s) will result in more participants experiencing little or no disability (mRS 0–2) at 3 months post-stroke (primary), fewer deaths at 3 months, fewer and less severe complications during the intervention period, faster recovery of unassisted walking, and...

To explore whether plaque and gingival bleeding are more frequently experienced by adolescents with juvenile idiopathic arthritis (JIA) compared to matched controls without JIA; explore whether surface- and site-specific periodontal outcomes vary between the two groups; and for participants with JIA, investigate associations between disease-specific features and periodontal outcomes. In this comparative cross-sectional study, selected surfaces, and sites of index teeth in 10–16-year-olds with JIA and matched controls were examined by modified versions of Simplified...

To explore whether plaque and gingival bleeding are more frequently experienced by adolescents with juvenile idiopathic arthritis (JIA) compared to matched controls without JIA; explore whether surface- and site-specific periodontal outcomes vary between the two groups; and for participants with JIA, investigate associations between disease-specific features and periodontal outcomes. In this comparative cross-sectional study, selected surfaces, and sites of index teeth in 10–16-year-olds with JIA and matched controls were examined by modified versions of Simplified...

Additional file 5. Results from follow-up measurements for the unmatched cohort.

Supplemental data for JCEM.

Supplemental data for JCEM.

Abstract Background Studies suggest increased risk for an outcome in people with joint exposures that share common causal pathways. The objective of this study was to determine the risk of incident acute myocardial infarction (AMI) following exposure to both albuminuria and/or anxiety and depression symptoms. Methods Participants who provided urine samples to the HUNT2 (1995–97) or HUNT3 (2007–2009) surveys were followed until the end of 2016. Albuminuria was measured by Albumin Creatine Ratio (ACR) and...

Additional file 1: Score sheet for assessment of humane end point.

Abstract Objective Multiple myeloma is a haematological malignancy characterized by proliferation of monoclonal plasma cells in the bone marrow. Development of resistance and minimal residual disease remain challenging in the treatment of multiple myeloma. Transforming growth factor-β activated kinase 1 (TAK1) has recently gained attention as a potential drug target in multiple myeloma. This study aimed at determining the in vivo effects of TAK1-inhibitors in a Vκ*MYC multiple myeloma mouse model. Results We treated mice...

: Meningioma has a prevalence around 1% in the population and with the increasing use and availability of diagnostic imaging modalities incidental meningiomas are increasingly detected. There is no clear consensus on their management, although several guidelines suggest firsthand active monitoring if no aggravating factors emerge. However, no collective guidelines on follow-up interval exist. This narrative review covers the epidemiology, diagnosis, growth prediction and management strategies of incidental meningioma. : Overdiagnosis and excessive follow-up are...

Supplementary Material 2

Supplementary Material 2

Additional file 1: Supplementary Table 1. Complete Case Analysis related to Table 2. Hazard Ratios (HR) and 95% confidence intervals (CI) for AMI during follow-up. Supplementary Table 2. Mechanisms related to missing on the physical activity question. Supplementary Table 3. Number (n, %) of participants* without and with Acute Myocardial Infarction (AMI) in Complete Case.

Additional file 1: Table S1. Report in accordance with the COREQ guidelines-checklist for reporting qualitative research. Description of data: Completed checklist in accordance with the COREQ guidelines.

Additional file 1: Table S1. Report in accordance with the COREQ guidelines-checklist for reporting qualitative research. Description of data: Completed checklist in accordance with the COREQ guidelines.

Additional file 2: Table S2. The Cochrane bias test for the articles included in the review. The Cochrane bias test analysis of the reviewed articles.