49 Works

Characterization of hierarchical structures in remelted Ni-Mn-Ga substrates for directed energy deposition manufacturing of single crystals

Paplham Tyler, Jakub Toman & Markus Chmielus

Investigating targettable pathways in Robinow Syndrome

Heather Szabo Rogers

Building Workplace Democracy

Trevor Young-Hyman

Evaluating Prescription Drug Subsidies for Diabetics: Effects on Medication Adherence and Health Outcomes

Eric Roberts & Immaculada Hernandez

Locomotor Adaptability for Community Mobility of Older Adults: The Role of Gait Automaticity

Andrea Rosso, Gelsy Torres-Oviedo & Andrea Weinstein

Pittsburgh Phage Project (P3)

John Williams, Jennifer Bomberger, Vaughn Cooper, Tim Corcoran, Yohei Doi, Balasubramani Goundappa, Ghady Haidar, Graham Hatfull, Alina Iovleva, Geoff Kurland, Seema Lakdawala, Marian Michaels, Stephanie Mitchell, Lisa Parker, Jim Pipas, Doug Reed, Ryan Shields, Fernanda Silveira, Daria Van Tyne, Anna Wang-Erickson & Steve Wisniewski

Data from: Nonnative old-field species inhabit early-season phenological niches and exhibit unique sensitivity to climate

Rachel Reeb, Isabel Acevedo, Mason Heberling & Sara Kuebbing
Native and nonnative plant species can exhibit differences in the timing of their reproductive phenology as well as their phenological sensitivity to climate. These contrasts may influence species’ interactions and the invasion potential of nonnative species; however, a limited number of phenology studies expressly consider phenological mismatches among native and nonnative species over broad spatial or temporal scales. To fill this knowledge gap, we used two complementary approaches: first, we quantified the flowering phenology of...

Mouse substantia nigra responses to optogenetic stimulation of projections from striatum and globus pallidus

Ryan Phillips, Ian Rosner, Aryn Gittis & Jonathan Rubin
As a rodent basal ganglia (BG) output nucleus, the substantia nigra pars reticulata (SNr) is well positioned to impact behavior. SNr neurons receive GABAergic inputs from the striatum (direct pathway) and globus pallidus (GPe, indirect pathway). Dominant theories of action selection rely on these pathways' inhibitory actions. Yet, experimental results on SNr responses to these inputs are limited and include excitatory effects. Our study combines experimental and computational work to characterize, explain, and make predictions...

Orthostatic hypotension, dizziness, neurology outcomes, and death in older adults, supplement methods & tables, STROND checklist

Stephen Juraschek, , Oscar L. Lopez, John S Gottdiener, Lewis A Lipsitz, Lewis H. Kuller & Kenneth J Mukamal
Objective To test the hypothesis that orthostatic hypotension (OH) might cause cerebral hypoperfusion and injury, we examined the longitudinal relationship between orthostatic hypotension (OH) or orthostatic symptoms and incident neurologic outcomes in a community population of older adults. Methods Cardiovascular Health Study (CHS) participants (≥65yrs) without dementia or stroke had blood pressure (BP) measured after lying 20-minutes and after standing 3-minutes. Participants reported dizziness immediately upon standing and any dizziness in the past 2wks. OH...

Data from: Novel sources of (co)variation in nestling begging behavior and hunger at different biological levels of analysis

Daniel Wetzel, Ariane Mutzel, Jonathan Wright & Niels Dingemanse
Biological hypotheses predicting patterns of offspring begging typically concern the covariance with hunger and/or development at specific hierarchical levels. For example, hunger drives within-individual patterns of begging, but begging also drives food intake among individuals within broods, and begging and food intake can covary positively or negatively among genotypes or broods. Testing biological phenomena that occur at multiple levels therefore requires the partitioning of covariance between traits of interest to ensure that each level-specific relationship...

Neural activity during a simple reaching task in macaques is counter to gating and rebound in basal ganglia-thalamic communication

Bettina Schwab, Daisuke Kase, Andrew Zimnik, Robert Rosenbaum, Marcello Codianni, Jonathan Rubin & Robert Turner
Task-related activity in the ventral thalamus, a major target of basal ganglia output, is often assumed to be permitted or triggered by changes in basal ganglia activity through gating- or rebound-like mechanisms. To test those hypotheses, we sampled single-unit activity from connected basal ganglia output and thalamic nuclei (globus pallidus-internus, GPi, and ventrolateral-anterior nucleus, VLa) in monkeys performing a reaching task. Rate increases were the most common peri-movement change in both nuclei. Moreover, peri-movement changes...

Data associated with \"Floral pigmentation has responded rapidly to global change in ozone and temperature\"

Matthew Koski, Drew MacQueen & Tia-Lynn Ashman
Across kingdoms, organisms ameliorate UV stress by increasing UV-absorbing pigmentation. Rapid ozone degradation during the 20th century resulted in elevated UV incidence, yet pigmentation responses to this aspect of global change have yet to be demonstrated. In flowering plants, UV exposure favors larger areas of UV-absorbing pigmentation on petals, which protects pollen from UV-damage. Pigmentation also affects floral thermoregulation, suggesting climate warming may additionally impact pigmentation. We used 1238 herbarium specimens collected from 1941 to...

Supporting Data: Effect of various pore fluids on the strength of granite

guanyi lu, Wu Zhao, Jiangnan Zhang & Andrew Bunger

Transnational Dialogues in Afro-Latin American and Afro-Latinx Studies

Michele Reid, Shawn Michelle Alfonso Wells, Reid Andrews, Jerome Branche, Gina Ann Garcia, Martha Mantilla & Luis Van Fossen Bravo

Predicting resistance to amyloid-beta deposition and cognitive resilience in the oldest-old

Beth Snitz
Objective: To explore long-term predictors of avoiding amyloid-beta (Aβ) deposition and maintaining unimpaired cognition as outcomes in the oldest old. Methods: In a longitudinal observational cohort study, N=100 former participants of the Ginkgo Evaluation of Memory Study (GEMS; 2000-2008) completed biannual Pittsburgh Compound B (PiB)-PET imaging and annual clinical-cognitive evaluations beginning in 2010. Most recent Aβ status and cognitive status were selected for each participant. Longitudinal outcomes included change in serial Aβ and cognitive tests....

Do dense layers of invasive plants elevate the foraging intensity of small mammals in temperate deciduous forests? A case study from Pennsylvania, USA

Ryan M. Utz, Alysha Slater, Hannah R. Rosche & Walter P. Carson
Monospecific stands of invasive plants can dramatically restructure habitat for fauna, thereby elevating population densities or promoting foraging of consumer species who benefit in the altered habitat. For example, dense stands of invasive plants may protect small mammals from predators, which in turn could increase foraging pressure on seeds that small mammals feed upon. We used a before-after, control-impact experimental design to test whether small mammal capture rates were higher and giving-up densities (GUDs) lower...

Right ventricular contractility and load in HIV associated pulmonary hypertension

Arun Rajaratnam, Marc Simon, Alison Morris, Sofiya Rehman, Prerna Sharma, Melissa Saul, Rebecca Vanderpool, Mark Gladwin & Vikas Singh
Background: People living with human immunodeficiency virus (PLWH) are at risk of developing pulmonary hypertension (PH) and right ventricular (RV) dysfunction, but understanding of the relationship of RV function to afterload (RV-PA coupling) is limited. We evaluated the clinical and hemodynamic characteristics of human immunodeficiency virus (HIV)-associated PH. Methods: We performed a retrospective review of patients with a diagnosis of HIV undergoing right heart catheterization (RHC) from 2000-2016 in a tertiary care center. Inclusion criteria...

Attacking the Global Plastics Waste Problem

Eric Beckman, Melissa Bilec, Vikas Khanna, Gotz Veser, Peng Liu, Amy Wildermuth & Joshua Galperin

Safely Staging Sex and Violence for the Academic Performer

Karen Gilmer

The emergence of Corporate Venture Capital in China: A Field Study

Ravi Madhavan

Grandparents raising grandchildren: A Strength-Based Perspective and Intervention

Fengyan Tang & Elizabeth Farmer

Deciphering Redox Free Radical Mechanisms of 15LOX/PEBP1-Driven Ferroptosis in Skin

Yuri Bunimovich, Valerian E. Kagan & Sunil Saxena

Registration Year

  • 2020
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Affiliations

  • University of Pittsburgh
    49
  • Carnegie Mellon University
    3
  • Northwestern University
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  • Massachusetts General Hospital
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  • University of Washington
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  • Max Planck Institute for Ornithology
    1
  • Estación Biológica de Doñana
    1
  • Carnegie Mellon University
    1
  • Stanford University
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  • Utah State University
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