64 Works

Data from: Using structured eradication feasibility assessment to prioritise the management of new and emerging invasive alien species in Europe

Olaf Booy, Peter A. Robertson, Niall Moore, Jess Ward, Helen E. Roy, Tim Adriaens, Richard Shaw, Johan Van Valkenburg, Gabe Wyn, Sandro Bertolino, Olivier Blight, Etienne Branquart, Giuseppe Brundu, Joe Caffrey, Dario Capizzi, Jim Casaer, Olivier De Clerck, Neil Coughlan, Eithne Davis, Jaimie Dick, Franz Essl, Guillaume Fried, Piero Genovesi, Pablo González-Moreno, Frank Hysentruyt … & Aileen C. Mill
Prioritising the management of invasive alien species (IAS) is of global importance and within Europe integral to the EU IAS regulation. To prioritise management effectively the risks posed by IAS need to be assessed, but so too does the feasibility of their management. While risk of IAS to the EU has been assessed, the feasibility of management has not. We assessed the feasibility of eradicating 60 new (not yet established) and 35 emerging (established with...

Note on the Fortune of the Epistles of Marcantonio Sabellico: The Case of Matteo Bandello

Maria Teresa Lanieri

Strategie di valorizzazione e promozione in chiave turistica del patrimonio culturale nelle aree interne. Un caso in Sardegna

Silvia Battino & Salvatore LAMPREU

Additional file 2 of A blood DNA methylation biomarker for predicting short-term risk of cardiovascular events

Andrea Cappozzo, Cathal McCrory, Oliver Robinson, Anna Freni Sterrantino, Carlotta Sacerdote, Vittorio Krogh, Salvatore Panico, Rosario Tumino, Licia Iacoviello, Fulvio Ricceri, Sabina Sieri, Paolo Chiodini, Gareth J. McKay, Amy Jayne McKnight, Frank Kee, Ian S. Young, Bernadette McGuinness, Eileen M. Crimmins, Thalida Em Arpawong, Rose Anne Kenny, Aisling O’Halloran, Silvia Polidoro, Giuliana Solinas, Paolo Vineis, Francesca Ieva … & Giovanni Fiorito
Additional file 2. Supplementary Tables S1, S2, and S3.

Validity and reliability of a french version of the olfactory disorders questionnaire

Jérôme R. Lechien, Luigi A. Vaira, Serge D. Le Bon, Roxane Geerts, Paolo Boscolo-Rizzo & Sven Saussez
Abstract Objective To validate a French version of the Olfactory Disorders Questionnaire (Fr-ODQ). Methods Patients with olfactory disorder (OD) and controls were enrolled from two medical centers. Individuals completed the Fr-ODQ and the French version of the sinonasal outcome tool-22 (SNOT-22). The extended Sniffin'Sticks procedure was used to test odor Threshold, Discrimination, and Identification (TDI). Cronbach’s alpha was used to measure the internal consistency of Fr-ODQ. The reliability and the external validity were evaluated through...

Additional file 1 of A systematic review of cost-utility analyses of screening methods in latent tuberculosis infection in high-risk populations

James Mahon, Sophie Beale, Hayden Holmes, Mick Arber, Vladyslav Nikolayevskyy, Riccardo Alagna, Davide Manissero, David Dowdy, Giovanni Battista Migliori, Giovanni Sotgiu & Raquel Duarte
Additional file 1. Search strategy.

Additional file 2 of Landscape of immune-related signatures induced by targeting of different epigenetic regulators in melanoma: implications for immunotherapy

Andrea Anichini, Alessandra Molla, Gabriella Nicolini, Valentina Eleonora Perotti, Francesco Sgambelluri, Alessia Covre, Carolina Fazio, Maria Fortunata Lofiego, Anna Maria Di Giacomo, Sandra Coral, Antonella Manca, Maria Cristina Sini, Marina Pisano, Teresa Noviello, Francesca Caruso, Silvia Brich, Giancarlo Pruneri, Andrea Maurichi, Mario Santinami, Michele Ceccarelli, Giuseppe Palmieri, Michele Maio & Roberta Mortarini
Additional file 2: Supplementary Figs. S1 to S21. Supplementary Fig. S1. Expression in ten melanoma cell lines of genes and gene families targeted by epigenetic drugs. Supplementary Fig. S2. Differentiation profile of melanoma cell lines. Supplementary Fig. S3. Susceptibility of ten melanoma cell lines to the anti-proliferative effects of epigenetic drugs. Supplementary Fig. S4. Methylation status of LINE-1, MAGE-A1 and NY-ESO-1 in 9 melanoma cell lines treated with guadecitabine. Supplementary Fig. S5. Volcano plot of...

Additional file 5 of Landscape of immune-related signatures induced by targeting of different epigenetic regulators in melanoma: implications for immunotherapy

Andrea Anichini, Alessandra Molla, Gabriella Nicolini, Valentina Eleonora Perotti, Francesco Sgambelluri, Alessia Covre, Carolina Fazio, Maria Fortunata Lofiego, Anna Maria Di Giacomo, Sandra Coral, Antonella Manca, Maria Cristina Sini, Marina Pisano, Teresa Noviello, Francesca Caruso, Silvia Brich, Giancarlo Pruneri, Andrea Maurichi, Mario Santinami, Michele Ceccarelli, Giuseppe Palmieri, Michele Maio & Roberta Mortarini
Additional file 5: Supplementary Table S3. Antibodies used in quantitative western blot analysis.

Additional file 7 of Landscape of immune-related signatures induced by targeting of different epigenetic regulators in melanoma: implications for immunotherapy

Andrea Anichini, Alessandra Molla, Gabriella Nicolini, Valentina Eleonora Perotti, Francesco Sgambelluri, Alessia Covre, Carolina Fazio, Maria Fortunata Lofiego, Anna Maria Di Giacomo, Sandra Coral, Antonella Manca, Maria Cristina Sini, Marina Pisano, Teresa Noviello, Francesca Caruso, Silvia Brich, Giancarlo Pruneri, Andrea Maurichi, Mario Santinami, Michele Ceccarelli, Giuseppe Palmieri, Michele Maio & Roberta Mortarini
Additional file 7: Supplementary Table S5. Immune-related gene modulation by epigenetic drugs and by combinatorial treatments.

Data from: Ecological niche differentiation in peripheral populations: a comparative analysis of eleven Mediterranean plant species

Guillaume Papuga, Perrine Gauthier, Virginie Pons, Emmanuele Farris & John D. Thompson
Aim: The “central-peripheral” hypothesis has provided a baseline for many studies of population dynamics and genetic variability at species distribution limits. Although peripheral populations are often assumed to occur in ecologically marginal conditions, little is known about whether they effectively occur in a distinct ecological niche. Location: Western Mediterranean basin. Time Period: 2013-2014. Major taxa studied: A cross-taxa analysis of 11 Mediterranean vascular plants. Methods: We quantified variation in the ecological niche between populations at...

Data from: Influence of genetic drift on patterns of genetic variation: the footprint of aquaculture practices in Sparus aurata (Teleostei: Sparidae)

Piero Cossu, Fabio Scarpa, Daria Sanna, Tiziana Lai, Gian Luca Dedola, Marco Curini-Galletti, Laura Mura, Nicola Fois & Marco Casu
Aquaculture finfish production based on floating cage technology has raised increasing concerns on the genetic integrity of natural populations. Accidental mass escapes can induce the loss of genetic diversity in wild populations by increasing genetic drift and inbreeding. Farm escapees likely represent an important issue in the gilthead sea bream, which accounted for 76.4% of total escapes recorded in Europe during a three-year survey. Here, we investigated patterns of genetic variation in farmed and wild...

Past, present and future of chamois science

Luca Corlatti, Laura Iacolina, Toni Safner, Marco Apollonio, Elena Buzan, Francesco Ferretti, Sabine Hammer, Juan Herrero, Luca Rossi, Emmanuel Serrano, Mari Cruz Arnal, Francesca Brivio, Roberta Chirichella, Antonella Cotza, Barbara Crestanello, Johan Espunyes, Daniel Fernández De Luco, Saskia Friedrich, Dragan Gačić, Laura Grassi, Stefano Grignolio, Heidi Hauffe, Kresmir Kavčić, Andreas Kinser, Francesca Lioce … & Nikica Šprem
The chamois Rupicapra spp. is the most abundant mountain ungulate of Europe and the Near East, where it occurs as two species, the Northern chamois R. rupicapra and the Southern chamois R. pyrenaica. Here, we provide a state-of-the-art overview of research trends and the most challenging issues in chamois research and conservation, focusing on taxonomy and systematics, genetics, life history, ecology and behavior, physiology and disease, management, and conservation. Research on Rupicapra has a longstanding...

Additional file 1 of A blood DNA methylation biomarker for predicting short-term risk of cardiovascular events

Andrea Cappozzo, Cathal McCrory, Oliver Robinson, Anna Freni Sterrantino, Carlotta Sacerdote, Vittorio Krogh, Salvatore Panico, Rosario Tumino, Licia Iacoviello, Fulvio Ricceri, Sabina Sieri, Paolo Chiodini, Gareth J. McKay, Amy Jayne McKnight, Frank Kee, Ian S. Young, Bernadette McGuinness, Eileen M. Crimmins, Thalida Em Arpawong, Rose Anne Kenny, Aisling O’Halloran, Silvia Polidoro, Giuliana Solinas, Paolo Vineis, Francesca Ieva … & Giovanni Fiorito
Additional file 1. Supplementary Results and Supplementary Figures S1, S2, S3, and S4.

Additional file 2 of A blood DNA methylation biomarker for predicting short-term risk of cardiovascular events

Andrea Cappozzo, Cathal McCrory, Oliver Robinson, Anna Freni Sterrantino, Carlotta Sacerdote, Vittorio Krogh, Salvatore Panico, Rosario Tumino, Licia Iacoviello, Fulvio Ricceri, Sabina Sieri, Paolo Chiodini, Gareth J. McKay, Amy Jayne McKnight, Frank Kee, Ian S. Young, Bernadette McGuinness, Eileen M. Crimmins, Thalida Em Arpawong, Rose Anne Kenny, Aisling O’Halloran, Silvia Polidoro, Giuliana Solinas, Paolo Vineis, Francesca Ieva … & Giovanni Fiorito
Additional file 2. Supplementary Tables S1, S2, and S3.

A blood DNA methylation biomarker for predicting short-term risk of cardiovascular events

Andrea Cappozzo, Cathal McCrory, Oliver Robinson, Anna Freni Sterrantino, Carlotta Sacerdote, Vittorio Krogh, Salvatore Panico, Rosario Tumino, Licia Iacoviello, Fulvio Ricceri, Sabina Sieri, Paolo Chiodini, Gareth J. McKay, Amy Jayne McKnight, Frank Kee, Ian S. Young, Bernadette McGuinness, Eileen M. Crimmins, Thalida Em Arpawong, Rose Anne Kenny, Aisling O’Halloran, Silvia Polidoro, Giuliana Solinas, Paolo Vineis, Francesca Ieva … & Giovanni Fiorito
Abstract Background Recent evidence highlights the epidemiological value of blood DNA methylation (DNAm) as surrogate biomarker for exposure to risk factors for non-communicable diseases (NCD). DNAm surrogate of exposures predicts diseases and longevity better than self-reported or measured exposures in many cases. Consequently, disease prediction models based on blood DNAm surrogates may outperform current state-of-the-art prediction models. This study aims to develop novel DNAm surrogates for cardiovascular diseases (CVD) risk factors and develop a composite...

Additional file 9 of Landscape of immune-related signatures induced by targeting of different epigenetic regulators in melanoma: implications for immunotherapy

Andrea Anichini, Alessandra Molla, Gabriella Nicolini, Valentina Eleonora Perotti, Francesco Sgambelluri, Alessia Covre, Carolina Fazio, Maria Fortunata Lofiego, Anna Maria Di Giacomo, Sandra Coral, Antonella Manca, Maria Cristina Sini, Marina Pisano, Teresa Noviello, Francesca Caruso, Silvia Brich, Giancarlo Pruneri, Andrea Maurichi, Mario Santinami, Michele Ceccarelli, Giuseppe Palmieri, Michele Maio & Roberta Mortarini
Additional file 9 Supplementary Table S7. Prognostic significance of genes in the guadecitabine and JQ1 immune-related signatures in the Cancer Genome Atlas (TCGA) melanoma dataset.

Additional file 5 of Landscape of immune-related signatures induced by targeting of different epigenetic regulators in melanoma: implications for immunotherapy

Andrea Anichini, Alessandra Molla, Gabriella Nicolini, Valentina Eleonora Perotti, Francesco Sgambelluri, Alessia Covre, Carolina Fazio, Maria Fortunata Lofiego, Anna Maria Di Giacomo, Sandra Coral, Antonella Manca, Maria Cristina Sini, Marina Pisano, Teresa Noviello, Francesca Caruso, Silvia Brich, Giancarlo Pruneri, Andrea Maurichi, Mario Santinami, Michele Ceccarelli, Giuseppe Palmieri, Michele Maio & Roberta Mortarini
Additional file 5: Supplementary Table S3. Antibodies used in quantitative western blot analysis.

Additional file 1 of High-flow nasal cannula versus non-invasive ventilation for acute hypercapnic respiratory failure in adults: a systematic review and meta-analysis of randomized trials

N. Ovtcharenko, E. Ho, W. Alhazzani, A. Cortegiani, B. Ergan, R. Scala, G. Sotgiu, D. Chaudhuri, S. Oczkowski & K. Lewis
Additional file 1: Table S1. Embase and Medline Search Results. Table S2. Cochrane Central Search Results. Table S3. Excluded Studies. Table S4. Risk of Bias Table. Fig. S1. Forest plot of mortality—subgroup analysis by risk of bias. Fig. S2. Forest plot of mortality—subgroup analysis excluding Wang et al. Fig. S3. Forest plot of intubation—subgroup analysis by risk of bias. Fig. S4. Forest plot of intubation—subgroup analysis excluding Wang et al. Fig. S5. Forest plot of...

High-flow nasal cannula versus non-invasive ventilation for acute hypercapnic respiratory failure in adults: a systematic review and meta-analysis of randomized trials

N. Ovtcharenko, E. Ho, W. Alhazzani, A. Cortegiani, B. Ergan, R. Scala, G. Sotgiu, D. Chaudhuri, S. Oczkowski & K. Lewis
Abstract Background Non-invasive ventilation (NIV) with bi-level positive pressure ventilation is a first-line intervention for selected patients with acute hypercapnic respiratory failure. Compared to conventional oxygen therapy, NIV may reduce endotracheal intubation, death, and intensive care unit length of stay (LOS), but its use is often limited by patient tolerance and treatment failure. High-flow nasal cannula (HFNC) is a potential alternative treatment in this patient population and may be better tolerated. Research question For patients...

Additional file 1 of A systematic review of cost-utility analyses of screening methods in latent tuberculosis infection in high-risk populations

James Mahon, Sophie Beale, Hayden Holmes, Mick Arber, Vladyslav Nikolayevskyy, Riccardo Alagna, Davide Manissero, David Dowdy, Giovanni Battista Migliori, Giovanni Sotgiu & Raquel Duarte
Additional file 1. Search strategy.

Additional file 1 of Validity and reliability of a french version of the olfactory disorders questionnaire

Jérôme R. Lechien, Luigi A. Vaira, Serge D. Le Bon, Roxane Geerts, Paolo Boscolo-Rizzo & Sven Saussez
Additional file 1. Appendix 1: The French version of Olfactory Disorder Questionnaire.

Data from: Genomic diversity and differentiation of a managed island wild boar population

Laura Iacolina, Massimo Scandura, Daniel J. Goedbloed, Panoraia Alexandri, Richard P. M. A. Crooijmans, Greger Larson, Alan Archibald, Marco Apollonio, Lawrence B. Schook, Martien A. Groenen & Hendrik-Jan Megens
The evolution of island populations in natural systems is driven by local adaptation and genetic drift. However, evolutionary pathways may be altered by humans in several ways. The wild boar (WB) (Sus scrofa) is an iconic game species occurring in several islands, where it has been strongly managed since prehistoric times. We examined genomic diversity at 49 803 single-nucleotide polymorphisms in 99 Sardinian WBs and compared them with 196 wild specimens from mainland Europe and...

Data from: Genome-wide SNP data unveils the globalization of domesticated pigs

Bin Yang, Leilei Cui, Miguel Perez-Enciso, Aleksei Traspov, Richard P. M. A. Crooijmans, Natalia Zinovieva, Lawrence B. Schook, Alan Archibald, Kesinee Gatphayak, Christophe Knorr, Alex Triantafyllidis, Panoraia Alexandri, Gono Semiadi, Olivier Hanotte, Deodália Dias, Peter Dovč, Pekka Uimari, Laura Iacolina, Massimo Scandura, Martien A. M. Groenen, Lusheng Huang & Hendrik-Jan Megens
Background: Pigs were domesticated independently in Eastern and Western Eurasia early during the agricultural revolution, and have since been transported and traded across the globe. Here, we present a worldwide survey on 60K genome-wide single nucleotide polymorphism (SNP) data for 2093 pigs, including 1839 domestic pigs representing 122 local and commercial breeds, 215 wild boars, and 39 out-group suids, from Asia, Europe, America, Oceania and Africa. The aim of this study was to infer global...

Data from: Molecular analysis of carnivore Protoparvovirus detected in white blood cells of naturally infected cats

Andrea Balboni, Francesca Bassi, Stefano De Arcangeli, Rosanna Zobba, Carla Dedola, Alberto Alberti & Mara Battilani
Background: Cats are susceptible to feline panleukopenia virus (FPV) and canine parvovirus (CPV) variants 2a, 2b and 2c. Detection of FPV and CPV variants in apparently healthy cats and their persistence in white blood cells (WBC) and other tissues when neutralising antibodies are simultaneously present, suggest that parvovirus may persist long-term in the tissues of cats post-infection without causing clinical signs. The aim of this study was to screen a population of 54 cats from...

Restoration efforts of the seagrass Posidonia oceanica: a collated evidence review dataset

Arianna Pansini, Maria Del Mar Bosch-Belmar, Manuel Berlino, Gianluca Sarà & Giulia Ceccherelli
Seagrass meadows are important shallow coastal ecosystems due to their contribution to enhancing biodiversity, nutrient cycling, carbon burial, and sediment stabilisation, but the maintenance of their integrity has been threatened by several anthropogenic disturbances. Active restoration is considered a reliable strategy to enhance recovery of seagrass ecosystems, and decision making for correct seagrass restoration management requires relying on valuable information regarding the effectiveness of past restoration actions and experimental efforts. Previous experimental efforts and human-mediated...

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    64
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