4 Works

Data from: Differentially expressed mRNA targets of differentially expressed miRNAs predict changes in the TP53 axis and carcinogenesis related pathways in human keratinocytes chronically exposed to arsenic

Laila Al-Eryani, Sabine Waigel, Ashish Tyagi, Jana Peremarti, Samantha F. Jenkins, Chendil Damodaran & J. Christopher States
Background: Arsenic is a widely distributed toxic natural element. Chronic arsenic ingestion causes several cancers, especially skin cancer. Arsenic-induced cancer mechanisms are not well defined, but several studies indicate that mutation is not the driving force and that microRNA expression changes play a role. Chronic low arsenite exposure malignantly transforms immortalized human keratinocytes (HaCaT), serving as a model for arsenic-induced skin carcinogenesis. Hypothesis: Early changes in miRNA expression in HaCaT cells chronically exposed to arsenite...

Data from: Decomposition of coarse woody debris in a long-term litter manipulation experiment: a focus on nutrient availability

Evan M. Gora, Emma J. Sayer, Benjamin L. Turner & Edmund V. J. Tanner
1.The majority of aboveground carbon in tropical forests is stored in wood, which is returned to the atmosphere during decomposition of coarse woody debris. However, the factors controlling wood decomposition have not been experimentally manipulated over time scales comparable to the length of this process. 2.We hypothesized that wood decomposition is limited by nutrient availability and tested this hypothesis in a long-term litter addition and removal experiment in a lowland tropical forest in Panama. Specifically,...

Data from: Arachnid aloft: directed aerial descent in neotropical canopy spiders

Stephen P Yanoviak, Yonatan Munk & Robert Dudley
The behaviour of directed aerial descent has been described for numerous taxa of wingless hexapods as they fall from the tropical rainforest canopy, but is not known in other terrestrial arthropods. Here, we describe similar controlled aerial behaviours for large arboreal spiders in the genus Selenops (Selenopidae). We dropped 59 such spiders from either canopy platforms or tree crowns in Panama and Peru; the majority (93%) directed their aerial trajectories towards and then landed upon...

Data from: Life in the cystic fibrosis upper respiratory tract influences competitive ability of the opportunistic pathogen Pseudomonas aeruginosa

Jeffrey John Bara, Zachary Matson & Susanna K. Remold
Understanding characteristic differences between host-associated and free-living opportunistic pathogens can provide insight into the fundamental requirements for success after dispersal to the host environment, and more generally into the ecological and evolutionary processes by which populations respond to simultaneous selection on complex interacting traits. We examined how cystic fibrosis (CF) associated and environmental isolates of the opportunistic pathogen Pseudomonas aeruginosa differ in the production of an ecologically important class of proteinaceous toxins known as bacteriocins,...

Registration Year

  • 2018

Resource Types

  • Dataset


  • University of Louisville
  • University of Cambridge
  • University of California, Berkeley
  • University of Barcelona
  • Smithsonian Tropical Research Institute
  • Lancaster University
  • The Open University