Functionalised acyclic cucurbiturils can be prepared in a straightforward fashion and provide access to a wide variety of substituted derivatives.

Abstract We report on triethylene glycol-based orthoformate cryptands, which adapt their bridgehead configurations in response to metal templates and intramolecular hydrogen bonding in a complex ma...

We report the template-free dynamic covalent self-assembly of a small orthoformate cryptand, which appears to be driven by the formation of two sets of intramolecular, four-centre hydrogen bonds.

The effect of inclusion complex formation on the fluorescence properties of berberine, a clinically important natural alkaloid, was studied using cucurbit[7]uril as macrocyclic host compound. The formation of a very stable 1:1 inclusion complex led to about 500-fold fluorescence intensity enhancement, which facilitated the detection of berberine even below nanomolar concentration. Addition of NaCl caused a significant change in the association constant and the fluorescence characteristics of the complex, whereas the variation of the anion...

Self-assembled orthoester cryptands offer appealing properties for applications in ion sensing and transport, such as convenient post-functionalization and tunable biodegradation.

The temperature dependence of the formation and dissociation kinetics of the flavopereirine–cucurbit[7]uril complex is revealed.

We report a solution NMR and X-ray crystallographic study on the anion affinity of all-cis 1,2,3,4,5,6-hexafluorocyclohexane, which has only recently become synthetically accessible.

The encapsulation of 4′,6-diamidino-2-phenylindole (DAPI) in the cucurbit[7]uril (CB7) cavity was studied by absorption, fluorescence, and NMR spectroscopic methods in aqueous solution. The profound change in the fluorescence characteristics was attributed to the formation of a very stable 1:1 inclusion complex. Three independent methods provided (1.1 ± 0.1) × 107 M−1 value for the binding constant. DAPI proved to be an excellent fluorescent probe for the investigation of the competitive binding of ionic liquids, surfactants,...