5 Works

Data from: Exploitation of interspecific diversity for monocot crop improvement

Julie King, Ian Armstead, John Harper, Luke Ramsay, John Snape, Robbie Waugh, Caron James, Ann Thomas, Dagmara Gasior, Rhys Kelly, Luned Roberts, Perry Gustafson, Ian King & L Ramsey
In many cultivated crop species there is limited genetic variation available for the development of new higher yielding varieties adapted to climate change and sustainable farming practises. The distant relatives of crop species provide a vast and largely untapped reservoir of genetic variation for a wide range of agronomically important traits that can be exploited by breeders for crop improvement. In this paper, in what we believe to be the largest introgression programme undertaken in...

Data from: Quorum sensing and cheating in bacterial biofilms

Roman Popat, Shanika A. Crusz, Marco Messina, Paul Williams, Stuart A. West & Stephen P. Diggle
The idea from human societies that self-interest can lead to a breakdown of cooperation at the group level is sometimes termed the public goods dilemma. We tested this idea in the opportunistic bacterial pathogen, Pseudomonas aeruginosa, by examining the influence of putative cheats that do not cooperate via cell-to-cell signalling (quorum-sensing, QS). We found that: (i) QS cheating occurs in biofilm populations owing to exploitation of QS-regulated public goods; (ii) the thickness and density of...

Data from: Analysis of genome-wide structure, diversity and fine mapping of Mendelian traits in traditional and village chickens

David Wragg, Joram M. Mwacharo, Paul M. Hocking, Olivier Hanotte & Jose A. Alcalde
Extensive phenotypic variation is a common feature among village chickens found throughout much of the developing world, and in traditional chicken breeds that have been artificially selected for traits such as plumage variety. We present here an assessment of traditional and village chicken populations, for fine mapping of Mendelian traits using genome-wide single-nucleotide polymorphism (SNP) genotyping while providing information on their genetic structure and diversity. Bayesian clustering analysis reveals two main genetic backgrounds in traditional...

Data from: Macroparasites at peripheral sites of infection are major and dynamic modifiers of systemic anti-microbial pattern recognition responses

Ida M. Friberg, Susan Little, Catriona Ralli, Ann Lowe, Amy Hall, Joseph A. Jackson & Jan E. Bradley
Immune defences and the maintenance of immunological homeostasis in the face of pathogenic and commensal microbial exposures are channelled by innate anti-microbial pattern recognition receptors (PRRs) such as toll-like receptors (TLRs). Whilst PRR-mediated response programmes are the result of long-term host-pathogen or host-commensal co-evolutionary dynamics involving microbes, an additional possibility is that macroparasitic co-infections may be a significant modifier of such interactions. We demonstrate experimentally that macroparasites (the model gastrointestinal nematode, Heligmosomoides) at peripheral sites...

Data from: The island-mainland species turnover relationship

Yoel E. Stuart, Jonathan B. Losos & Adam C. Algar
Many oceanic islands are notable for their high endemism, suggesting that islands may promote unique assembly processes. However, mainland assemblages sometimes harbour comparable levels of endemism, suggesting that island biotas may not be as unique as often assumed. Here, we test the uniqueness of island biotic assembly by comparing the rate of species turnover among islands and the mainland, after accounting for distance decay and environmental gradients. We modeled species turnover as a function of...

Registration Year

  • 2012

Resource Types

  • Dataset


  • University of Nottingham
  • Aberystwyth University
  • University of Edinburgh
  • University of Missouri
  • James Hutton Institute
  • Harvard University
  • Pontifical Catholic University of Chile
  • University of Oxford
  • John Innes Centre