31 Works

The Double Helix of Theory and Practice: Celebrating Stephen J. Goldberg as a Scholar, Practitioner, and Mentor

Mara Olekalns, Donna Shestowsky, Sylvia Skratek & Ann-Sophie De Pauw

Population structure and demographic analyses of Acanthocybium solandri from the Indo-Pacific and Atlantic oceans

Joshua Thia
This repository contains scripts, data and results for a populaton genomics study of genetic structure and demography of wahoo, Acanthocybium solandri, published in Journal of Biogeography: Haro-Bilbao et al. (2021) Global connections with some genomic differentiation occur between Indo-Pacific and Atlantic Ocean wahoo, a large circumtropical pelagic fish. In this work, we generated population allele frequencies for wahoo sampled at 11 locations around the globe using a pooled ezRAD approach. Using thousands of genome-wide SNPs,...

Double-tagging scores of seabirds reveals that light-level geolocator accuracy is limited by species idiosyncrasies and equatorial solar profiles

Luke Halpin, Jeremy Ross, Raül Ramos, Rowan Mott, Nicholas Carlile, Nick Golding, José Manuel Reyes-González, Teresa Militão, Fernanda De Felipe, Zuzana Zajková, Marta Cruz Flores, Sarah Saldanha, Virginia Morera-Pujol, Leia Navarro-Herrero, Laura Zango, Jacob Gonzalez-Solis & Rohan Clarke
Light-level geolocators are popular bio-logging tools, with advantageous sizes, longevity, and affordability. Biologists tracking seabirds often presume geolocator spatial accuracies between 186-202 km from previously-innovative, yet taxonomically, spatially, and computationally limited, studies. Using recently developed methods, we investigated whether assumed uncertainty norms held across a larger-scale, multispecies study. We field-tested geolocator spatial accuracy by synchronously deploying these with GPS loggers on scores of seabirds across five species and 11 Mediterranean Sea, East Atlantic and South...

Cracks in the mirror hypothesis: high specularity does not reduce detection or predation risk

Amanda Franklin, Katrina Rankin, Laura Ospina-Rozo, Iliana Medina, Jair Garcia, Leslie Ng, Caroline Dong, Lu-Yi Wang, Anne Aulsebrook & Devi Stuart-Fox
Some animals, including certain fish, beetles, spiders and Lepidoptera chrysalises, have such shiny or glossy surfaces that they appear almost mirror-like. A compelling but unsubstantiated hypothesis is that a highly specular or mirror-like appearance enhances survival by reflecting the surrounding environment and reducing detectability. We tested this hypothesis by asking human participants to wear a mobile eye-tracking device and locate highly realistic mirror-green and diffuse-green replica beetles against a variety of backgrounds in a natural...

Building data capacity in the not-for-profit sector: Interim report

Xiaofang Yao, Anthony McCosker, Kath Albury, Alexia Maddox & Jane Farmer

Single molecule tracking raw data: SOX18 and its dominant-negative mutant SOX18RaOp

Alex McCann, Jieqiong Lou, Mehdi Moustaqil, Matthew Graus, Ailisa Blum, Frank Fontaine, Hui Liu, Winnie Luu, Peter Koopman, Emma Sierecki, Yann Gambin, Frédéric Meunier, Zhe Liu, Elizabeth Hinde & Mathias Francois
Few genetically dominant mutations involved in human disease have been fully explained at the molecular level. In cases where the mutant gene encodes a transcription factor, the dominant-negative mode of action of the mutant protein is particularly poorly understood. Here, we studied the genome-wide mechanism underlying a dominant-negative form of the SOX18 transcription factor (SOX18RaOp) responsible for both the classical mouse mutant Ragged Opossum and the human genetic disorder Hypotrichosis-Lymphedema-Telangiectasia-Renal Syndrome. Combining three single-molecule imaging...

Genetic and phenotypic variation in Bathygobius cocosensis from East Australia (2014–2016)

Joshua Thia
Genetic and phenotypic data from an East Australian metapopulation of the intertidal goby, Bathygobius cocosensis (Bleeker 1854). Data was collected over three years (2014–2016) from juveniles and adult subpopulations at three sites: Point Cartwright, Hastings Point and Shellharbour. Genetic variation was characterised using genome-wide SNPs, obtained through pooled ezRAD sequencing. Phenotypic variation was characterised using geometric morphometric analysis of head shape morphology. The analyses contained in this repository are for a manuscript submitted to Molecular...

Variability, heritability and condition-dependence of the multidimensional male colour phenotype in a passerine bird

Marie Fan, Michelle Hall, Michael Roast, Anne Peters & Kaspar Delhey
Elaborate ornamental traits are commonly assumed to be honest signals of individual quality, owing to the presumed costs involved in their production and/or maintenance. Such traits are often highly variable, possibly because of condition-dependence and/or high underlying genetic variation, and it has been suggested that their expression should be more sensitive to condition and/or more heritable than non-ornamental traits. Many bird species display colourful plumage with multiple distinct patches of different developmental origins, forming complex...

Male reproductive effort might be evolving in the face of devastating disease in a threatened amphibian

Laura Brannelly, Rebecca J Webb, Zhixuan Jiang, Lee Berger, Lee F Skerratt & Laura F Grogan
The devastating infectious disease chytridiomycosis has caused declines of amphibians across the globe, yet some populations are persisting and even recovering. One understudied effect of wildlife disease is changes in reproductive effort. Here we aimed to understand if disease has plastic effects on reproduction and if reproductive effort could evolve with disease endemism. We compared the effects of experimental pathogen exposure (trait plasticity) and population-level disease history (evolution in trait baseline) on reproductive effort using...

A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity

Jieqiong Lou, Alex McCann, Mehdi Moustaqil, Matthew Graus, Ailisa Blum, Frank Fontaine, Hui Liu, Winnie Luu, Peter Koopman, Emma Sierecki, Yann Gambin, Frédéric Meunier, Zhe Liu, Elizabeth Hinde & Mathias Francois
Few genetically dominant mutations involved in human disease have been fully explained at the molecular level. In cases where the mutant gene encodes a transcription factor, the dominant-negative mode of action of the mutant protein is particularly poorly understood. Here, we studied the genome-wide mechanism underlying a dominant-negative form of the SOX18 transcription factor (SOX18RaOp) responsible for both the classical mouse mutant Ragged Opossum and the human genetic disorder Hypotrichosis-Lymphedema-Telangiectasia-Renal Syndrome. Combining three single-molecule imaging...

Clinicians’ opinions on recommending aspirin to prevent colorectal cancer to Australians aged 50 to 70 years: A qualitative study

Shakira Milton, Jennifer McIntosh, Thivagar Yogaparan, Pavithran Alphonse, Sibel Saya, Napin Karnchanachari, Peter Nguyen, Phyllis Lau, Finlay Macrae & Jon Emery
Objectives Australian guidelines recommend all 50 to 70-year-olds without existing contraindications consider taking low-dose aspirin (100 mg – 300 mg per day) for at least 2.5 years to reduce their risk of developing colorectal cancer. We aimed to explore clinicians’, practices, knowledge, opinions, and barriers and facilitators to the implementation of these new guidelines. Methods Semi-structured interviews were conducted with clinicians to whom the new guidelines may be applicable (familial cancer clinic staff (geneticists, oncologists...

Raw data for: Extreme climate shifts pest dominance hierarchy through thermal evolution and transgenerational plasticity

Liang Zhu, Ary Hoffmann, Shimin Li & Chunsen Ma
We conducted an 8-year field survey to link extreme high-temperature events to the shift in dominance hierarchy of two worldwide cereal aphid species (Rhopalosiphum padi and Sitobion avenae), which may respond rapidly through evolutionary or plastic responses to thermal extremes due to their short generation duration, clonal structure and high thermal sensitivity. To further understand the mechanism involved in this change in species’ dominance, we characterised aphid heat tolerance and demography of the 2 species...

Sexual selection and the population genetics of a selfish gene

Thomas Keaney, Theresa Jones & Luke Holman
The segregation distorter allele (SD) found in Drosophila melanogaster distorts Medelian inheritance in heterozygous males by causing developmental failure of non-SD spermatids, such that >90% of the surviving sperm carry SD. This within-individual advantage should cause SD to rapidly fix, and yet SD is typically rare in wild populations. Here, we explore whether this paradox can be resolved by sexual selection, by testing if males carrying three different variants of SD suffer reduced pre or...

Antibody features towards VAR2CSA and CSA binding infected erythrocytes in a cohort of pregnant women from PNG

Elizabeth Aitken, Amaya Ortega-Pajares, Agersew Alemu, Wina Hasang, Saber Dini, Holger Unger, Maria Ome-Kaius, Morten Nielsen, Ali Salanti, Joe Smith, Stephen Kent, P Mark Hogarth, Bruce Wines, Julie Simpson, Timon Damelang, Amy Chung & Stephen Rogerson
Plasmodium falciparum causes placental malaria, which results in adverse outcomes for mother and child. P. falciparum infected erythrocytes that express the parasite protein VAR2CSA on their surface can bind to placental chondroitin sulfate-A. It has been hypothesized that naturally acquired antibodies towards VAR2CSA protect against placental infection, but it has proven difficult to use measures of antibody to identify individuals protected from disease. We used a systems serology approach to identify naturally acquired antibody features...

Data from: Special care dentistry perception among dentists in Jakarta: an online survey study

Masita Mandasari, Hajer Derbi, Febrina Rahmayanti & Yuniardini Septorini Wimardhani
Special Care Dentistry (SCD) or Special Needs Dentistry is a branch of dentistry concerned with the oral health of people with a variety of medical conditions or limitations that require more than routine delivery of care. There were reports on oral status of special care patients and special interest group for SCD dentists in Indonesia has existed. However, there was not perception report on SCD amongst dentists in Jakarta. This paper will describe the perception...

Gene induction by natural toxins in Drosophila melanogaster

Charles Robin & Thuan-Jin Kee
The transcriptional response of third instar Drosophila larvae to food laced with caffeine, pyrethrum oil or neem oil was assessed using Agilent 4x44K printed microarrays. Among the most notable responsive genes were those belonging to cytochrome P450 and Ecdysone-like kinase gene families.

Single molecule tracking videos: SOX18 and its dominant-negative mutant SOX18RaOp

Alex McCann, Jieqiong Lou, Mehdi Moustaqil, Matthew Graus, Ailisa Blum, Frank Fontaine, Hui Liu, Winnie Luu, Peter Koopman, Emma Sierecki, Yann Gambin, Frédéric Meunier, Zhe Liu, Elizabeth Hinde & Mathias Francois
Few genetically dominant mutations involved in human disease have been fully explained at the molecular level. In cases where the mutant gene encodes a transcription factor, the dominant-negative mode of action of the mutant protein is particularly poorly understood. Here, we studied the genome-wide mechanism underlying a dominant-negative form of the SOX18 transcription factor (SOX18RaOp) responsible for both the classical mouse mutant Ragged Opossum and the human genetic disorder Hypotrichosis-Lymphedema-Telangiectasia-Renal Syndrome. Combining three single-molecule imaging...

Data from: Quantifying variation in female internal genitalia: no evidence for plasticity response to sexual conflict risk in a seed beetle

Blake Wyber, Kathryn McNamara, Liam Dougherty, Andrew Mehnert, Jeremy Shaw, Joseph Tomkins & Leigh Simmons
Sexually antagonistic coevolution can drive the evolution of male traits that harm females, and female resistance to those traits. While males have been found to vary their harmfulness to females in response to social cues, whether female resistance traits vary in response to social cues remains to be examined. Among seed beetles, male genital spines harm females during copulation and females might resist male harm via thickening of the reproductive tract walls. Here we develop...

From the Field to the Laboratory: The Theory-Practice Research of Peter J. Carnevale

Linda Putnam, Mara Olekalns, Donald Conlon & Carsten De Dreu

Labor Market Policies During an Epidemic

Serdar Birinci, Fatih Karahan, Yusuf Mercan & Kurt See
The COVID-19 pandemic has resulted in a marked slowdown of economic activity and the loss of many jobs. We look at two major policy responses designed to counteract the consequences of containment measures—the introduction of payroll subsidies and the expansion of unemployment insurance (UI)—and study their implications for the labour market and economic welfare. We develop a search model of the labour market and combine it with a standard epidemiological model. Our model features three...

Citations: The Renaissance Imitation Mass (CRIM)

Richard Freedman, Philippe Vendrix, David Fiala, Micah Walter, Emilio Sanfilippo, Raffaele Viglianti & Daniel Russo-Batterham

A Visual Essay: Enabling Entanglements of Cloth and the Body

Katve-Kaisa Kontturi & Vappu Jalonen

Effects of high and low-efficacy therapy in secondary progressive multiple sclerosis

Izanne Roos, Emmanuelle Leray, Romain Casey, Dana Horakova, Eva Havrdova, Guillermo Izquierdo, Sara Eichau, Francesco Patti, Gilles Edan, Marc Debouverie, Jean Pelletier, Serkan Ozakbas, Maria Pia Amato, Pierre Clavelou, Pierre Grammond, Cavit Boz, Katherine Buzzard, Olga Skibina, Jonathan Ciron, Oliver Gerlach, Francois Grand'Maison, Jeannette Lechner-Scott, Charles Malpas, Helmut Butzkueven, Sandra Vukusic … & Tomas Kalincik
Objective: To compare the clinical effectiveness of high- and low-efficacy treatments in patients with recently active and inactive secondary progressive multiple sclerosis (SPMS) after accounting for therapeutic lag. Methods: Patients treated with high- (natalizumab, alemtuzumab, mitoxantrone, ocrelizumab, rituximab, cladribine, fingolimod) or low-efficacy (interferon β, glatiramer acetate, teriflunomide) therapies after SPMS onset were selected from MSBase and OFSEP, two large observational cohorts. Therapeutic lag was estimated for each patient based on their demographic and clinical characteristics....

Explaining the worldwide distributions of two highly mobile species: Cakile edentula and C. maritima

Roger Cousens, Elliot Shaw, Rachael Fowler, Sara Ohadi, Michael Bayly, Rosemary Barrett, Josquin Tibbits, Allan Strand, Charles Willis, Kathleen Donohue & Philipp Robeck
Aim: If we are able to determine the geographic origin of an invasion, as well as its known area of introduction, we can better appreciate the innate environmental tolerance of a species and the strength of selection for adaptation that colonising populations have undergone. It also enables us to maximise the success of searches for effective biological control agents. We determined the number of successful colonisation events that have occurred throughout the world for two...

Measurements of tree motion in the wind collated from multiple studies undertaken in the UK, Puerto Rico and Australia between 1987-2015

T. Jackson, A. Wellpott, S. Van Bloem, A. Achim, K. James & B. Gardiner
This dataset contains high resolution measurements of tree motion in response to wind at six sites. The data was collected using sensors mounted directly onto the tree trunk. The sites are: Rivox, Kershope, Kyloe and Clocaenog in the UK. Guanica in Puerto Rico and six open-grown trees from Australia.

Registration Year

  • 2021
    31

Resource Types

  • Dataset
    25
  • Text
    4
  • Conference Paper
    1
  • Report
    1

Affiliations

  • University of Melbourne
    31
  • Monash University
    5
  • University of Queensland
    3
  • University of Sydney
    3
  • UNSW Sydney
    3
  • Janelia Farm Research Campus
    2
  • Department of Planning and Environment
    1
  • College of Charleston
    1
  • Lions Eye Institute
    1
  • Howard Hughes Medical Institute
    1