Introduction: Oxidative stress plays a role in the pathogenesis of rheumatoid arthritis (RA). Anthocyanin is a plant antioxidant. We investigated the therapeutic effects of anthocyanin extracted from black soybean seed coats (AEBS) in a murine model of collagen-induced arthritis (CIA) and human peripheral blood mononuclear cells (PBMCs), and explored possible mechanisms by which AEBS might exert anti-arthritic effects. Material and Methods: A CIA model was induced in DBA/1J mice. CIA was induced in DBA/1J mice....

Activation of plant pattern-triggered immunity (PTI) relies on the recognition of microbe-derived structures, termed patterns, through plant-encoded surface-resident pattern recognition receptors (PRRs). We show that proteobacterial translation initiation factor 1 (IF1) triggers PTI in Arabidopsis thaliana and related Brassicaceae species. Unlike for most other immunogenic patterns, IF1 elicitor activity cannot be assigned to a small peptide epitope, suggesting that tertiary fold features are required for IF1 receptor activation. We have deployed natural variation in IF1...

Additional file 2: Figure S5. Original image indicating AMPKa, p-AMPKa, ACC2, CPT1 and GAPDH for Western blots of figure 3c. Figure S6. Original image indicating CD133, Nestin, SOX2, Msi-1 and GAPDH for Western blots of figure 4b. Figure S7. Original image indicating CD133, Nestin, SOX2, Msi-1 and GAPDH for Western blots of figure 4e.

Background: The International Trauma Questionnaire (ITQ) is a self-report assessment focused on the core features of Post-Traumatic Stress Disorder (PTSD) and complex Post-Traumatic Stress Disorder (CPTSD). It is consistent with the organizing principles of the 11th revision to the WHO's International Classification of Diseases (ICD-11). Since the 1990s, the number of North Korean defectors (NKD) entering South Korea to escape human rights violations has been increasing rapidly, with 33,815 NKD settled by 2021. The South...

Additional file 1. Supplementary material-CONSORT diagram.

Abstract Background Understanding the motivational effects of supervised aerobic high-intensity interval training (HIIT) may help men with prostate cancer undergoing active surveillance initiate and maintain exercise behavior, however, few studies have addressed this question. This report explored exercise motivation in men with prostate cancer undergoing active surveillance participating in a randomized exercise trial. Methods The Exercise during Active Surveillance for Prostate Cancer (ERASE) trial randomized 52 men with prostate cancer on active surveillance to the...

Supplemental material, sj-tif-2-aor-10.1177_00034894221136998 for The analgesic Efficacy and Safety of Topically Applied Tramadol in Peritonsillar Space During Pediatric Adenotonsillectomy: A Meta-Analysis by Yun Jin Kang, Jin-Hee Cho and Se Hwan Hwang in Annals of Otology, Rhinology & Laryngology

Supplemental material, sj-tif-7-aor-10.1177_00034894221136998 for The analgesic Efficacy and Safety of Topically Applied Tramadol in Peritonsillar Space During Pediatric Adenotonsillectomy: A Meta-Analysis by Yun Jin Kang, Jin-Hee Cho and Se Hwan Hwang in Annals of Otology, Rhinology & Laryngology

Supplemental material, sj-docx-2-ajr-10.1177_19458924221150977 for The Efficacy of Olfactory Training as a Treatment for Olfactory Disorders Caused by Coronavirus Disease-2019: A Systematic Review and Meta-Analysis by Se Hwan Hwang, Sung Won Kim, Mohammed Abdullah Basurrah and Do Hyun Kim in American Journal of Rhinology & Allergy

Supplemental material, sj-docx-4-ajr-10.1177_19458924221150977 for The Efficacy of Olfactory Training as a Treatment for Olfactory Disorders Caused by Coronavirus Disease-2019: A Systematic Review and Meta-Analysis by Se Hwan Hwang, Sung Won Kim, Mohammed Abdullah Basurrah and Do Hyun Kim in American Journal of Rhinology & Allergy

Research Data for Lidocaine inhibits osteogenic differentiation of human dental pulp stem cells in vitro by Eun-Jung Kim, Ji-Uk Yoon, Cheul-Hong Kim, Ji-Young Yoon, Joo-Young Kim, Hyang-Sook Kim and Eun-Ji Choi in Journal of International Medical Research

Abstract Background Due to anthropogenic activities and global warming, the severity and distribution of harmful algal blooms (HABs) have been increasing steadily worldwide, including in South Korea (S. Korea). Previous studies reported that exposure to HABs could increase the risk of HAB-related diseases. However, very few studies examined the linkage between HABs and disease occurrence, particularly in S. Korea. The objective of this study was to evaluate the potential impact of HABs on neurodegenerative diseases...

Abstract Background Symptom burden and adverse treatment effects can negatively impact physical function, health-related outcomes, and quality of life in cancer survivors. Resistive exercise that improves skeletal muscle function can ameliorate these complications, but the central role of the skeletal muscle in mediating improvements in patient-related outcomes has not been explored. This protocol describes the rationale and methods for a systematic review that aims to determine the effects of resistive exercise on the skeletal muscle...

Additional file 14: Supplementary Table 2. Primer list for qRT-PCR analysis.

Additional file 1: Supplementary Fig. 1. t-distributed stochastic neighbor embedding (tSNE) plot colored based on the expression levels of candidate genes in each sample group.

Additional file 2. Study inclusion spreadsheet.

Supplemental material, sj-pdf-2-imr-10.1177_03000605221133655 for Prediction of homologous recombination deficiency from cancer gene expression data by Jun Kang, Jieun Lee, Ahwon Lee and Youn Soo Lee in Journal of International Medical Research

Supplemental material, sj-pdf-2-imr-10.1177_03000605221133655 for Prediction of homologous recombination deficiency from cancer gene expression data by Jun Kang, Jieun Lee, Ahwon Lee and Youn Soo Lee in Journal of International Medical Research

Additional file 10: Supplementary Figure 10. Different microbial communities by inoculation of probiotics in germ-free mice. a,b, Beta (Bray-Curtis distance) diversities of the gut microbiome between (a), before inoculation of probiotics (0th week, n = 13) and after inoculation of probiotics (8th week, n = 15) in germ-free mice and (b), types of treatment (Pre, n = 13; HFD, n = 5; B. longum, n = 5, B. bifidum, n = 5). Each below table...

Additional file 10: Supplementary Figure 10. Different microbial communities by inoculation of probiotics in germ-free mice. a,b, Beta (Bray-Curtis distance) diversities of the gut microbiome between (a), before inoculation of probiotics (0th week, n = 13) and after inoculation of probiotics (8th week, n = 15) in germ-free mice and (b), types of treatment (Pre, n = 13; HFD, n = 5; B. longum, n = 5, B. bifidum, n = 5). Each below table...

Additional file 12: Supplementary Figure 12. Summary of mechanisms of B. longum and B. bifidum for anti-obesity in HFD-induced obesity mice. Inoculation of B. longum and B. bifidum induced physiological changes of WAT, BAT, and liver to prevent HFD-induced obesity in mice.

Additional file 13: Supplementary Table 1. Clinical characteristics of human donors.

Additional file 13: Supplementary Table 1. Clinical characteristics of human donors.

Additional file 5: Supplementary Figure 5. Profiling of the gut microbiome in human donors by fatty liver. a, A total of 99 human samples were included in the analysis and were divided by Incidence of fatty liver b,c, Alpha (b, Shannon index) and beta (c, Bray Curtis distance) diversities of the gut microbiome between groups with normal liver (n = 52) and fatty liver (n = 43). Error bars represent the distribution of diversity scores....

Addition al file 1: Supplementary Fig. S1. CrPVIRES-ssRNA recruits immune cells into drain lymph node. C57BL/6 mice were intramuscularly injected with alum, CrPVIRES-ssRNA, and poly(I:C) for 48 h. Macrophage and T cells were analyzed using flow cytometry in drain inguinal lymph nodes. (A) Cell percentage of macrophages in the indicated groups (n = 3). (B, C) Cell percentage of CD4-positive T cells (B) and CD8-positive T cells (C) in drain inguinal lymph nodes (n =...