11 Works

Additional file 4 of Effects of urinary extracellular vesicles from prostate cancer patients on the transcriptomes of cancer-associated and normal fibroblasts

Lilite Sadovska, Pawel Zayakin, Cristina Bajo-Santos, Edgars Endzeliņš, Jānis Auders, Laura Keiša, Juris Jansons, Vilnis Lietuvietis & Aija Linē
Supplementary Material 4

Effects of urinary extracellular vesicles from prostate cancer patients on the transcriptomes of cancer-associated and normal fibroblasts

Lilite Sadovska, Pawel Zayakin, Cristina Bajo-Santos, Edgars Endzeliņš, Jānis Auders, Laura Keiša, Juris Jansons, Vilnis Lietuvietis & Aija Linē
Abstract Background Increasing evidence suggests that cancer-derived extracellular vesicles (EVs) alter the phenotype and functions of fibroblasts and trigger the reprogramming of normal fibroblasts into cancer-associated fibroblasts (CAFs). Here, we for the first time studied the effects of urinary EVs from PC patients and healthy males on the transcriptional landscape of prostate CAFs and normal foreskin fibroblasts. Methods Patient-derived prostate fibroblast primary cultures PCF-54 and PCF-55 were established from two specimens of PC tissues. EVs...

Additional file 2 of Effects of urinary extracellular vesicles from prostate cancer patients on the transcriptomes of cancer-associated and normal fibroblasts

Lilite Sadovska, Pawel Zayakin, Cristina Bajo-Santos, Edgars Endzeliņš, Jānis Auders, Laura Keiša, Juris Jansons, Vilnis Lietuvietis & Aija Linē
Supplementary Material 2

Additional file 3 of Effects of urinary extracellular vesicles from prostate cancer patients on the transcriptomes of cancer-associated and normal fibroblasts

Lilite Sadovska, Pawel Zayakin, Cristina Bajo-Santos, Edgars Endzeliņš, Jānis Auders, Laura Keiša, Juris Jansons, Vilnis Lietuvietis & Aija Linē
Supplementary Material 3

Additional file 3 of Effects of urinary extracellular vesicles from prostate cancer patients on the transcriptomes of cancer-associated and normal fibroblasts

Lilite Sadovska, Pawel Zayakin, Cristina Bajo-Santos, Edgars Endzeliņš, Jānis Auders, Laura Keiša, Juris Jansons, Vilnis Lietuvietis & Aija Linē
Supplementary Material 3

Additional file 4 of Effects of urinary extracellular vesicles from prostate cancer patients on the transcriptomes of cancer-associated and normal fibroblasts

Lilite Sadovska, Pawel Zayakin, Cristina Bajo-Santos, Edgars Endzeliņš, Jānis Auders, Laura Keiša, Juris Jansons, Vilnis Lietuvietis & Aija Linē
Supplementary Material 4

Data from: Microbiome symbionts and diet diversity incur costs on the immune system of insect larvae

Indrikis Krams, Sanita Kecko, Priit Jõers, Giedrius Trakimas, Didzis Elferts, Ronalds Krams, Severi Luoto, Markus J. Rantala, Inna Inashkina, Dita Gudrā, Dāvids Fridmanis, Jorge Contreras-Garduño, Lelde Grantiņa-Ieviņa & Tatjana Krama
Communities of symbiotic microorganisms that colonize the gastrointestinal tract play an important role in food digestion and protection against opportunistic microbes. Diet diversity increases the number of symbionts in the intestines, a benefit that is considered to impose no cost for the host organism. However, less is known about the possible immunological investments that hosts have to make in order to control the infections caused by symbiont populations that increase due to diet diversity. By...

Additional file 1 of Effects of urinary extracellular vesicles from prostate cancer patients on the transcriptomes of cancer-associated and normal fibroblasts

Lilite Sadovska, Pawel Zayakin, Cristina Bajo-Santos, Edgars Endzeliņš, Jānis Auders, Laura Keiša, Juris Jansons, Vilnis Lietuvietis & Aija Linē
Supplementary Material 1

Additional file 1 of Effects of urinary extracellular vesicles from prostate cancer patients on the transcriptomes of cancer-associated and normal fibroblasts

Lilite Sadovska, Pawel Zayakin, Cristina Bajo-Santos, Edgars Endzeliņš, Jānis Auders, Laura Keiša, Juris Jansons, Vilnis Lietuvietis & Aija Linē
Supplementary Material 1

Additional file 2 of Effects of urinary extracellular vesicles from prostate cancer patients on the transcriptomes of cancer-associated and normal fibroblasts

Lilite Sadovska, Pawel Zayakin, Cristina Bajo-Santos, Edgars Endzeliņš, Jānis Auders, Laura Keiša, Juris Jansons, Vilnis Lietuvietis & Aija Linē
Supplementary Material 2

Effects of urinary extracellular vesicles from prostate cancer patients on the transcriptomes of cancer-associated and normal fibroblasts

Lilite Sadovska, Pawel Zayakin, Cristina Bajo-Santos, Edgars Endzeliņš, Jānis Auders, Laura Keiša, Juris Jansons, Vilnis Lietuvietis & Aija Linē
Abstract Background Increasing evidence suggests that cancer-derived extracellular vesicles (EVs) alter the phenotype and functions of fibroblasts and trigger the reprogramming of normal fibroblasts into cancer-associated fibroblasts (CAFs). Here, we for the first time studied the effects of urinary EVs from PC patients and healthy males on the transcriptional landscape of prostate CAFs and normal foreskin fibroblasts. Methods Patient-derived prostate fibroblast primary cultures PCF-54 and PCF-55 were established from two specimens of PC tissues. EVs...

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