96 Works

Data from: Population genomics of wild and laboratory zebrafish (Danio rerio)

Andrew R Whiteley, Anuradha Bhat, Emilia P Martins, Richard L Mayden, M Arunachalam, Silva Uusi-Heikkilä, A.T.A. Ahmed, Jiwan Shrestha, Matthew Clark, Derek Stemple & Louis Bernatchez
Understanding a wider range of genotype-phenotype associations can be achieved through ecological and evolutionary studies of traditional laboratory models. Here, we conducted the first large-scale geographic analysis of genetic variation within and among wild zebrafish (Danio rerio) populations occurring in Nepal, India, and Bangladesh and we genetically compared wild populations to several commonly used lab strains. We examined genetic variation at 1,832 polymorphic EST-based SNPs and the cytb mitochondrial gene in 13 wild populations and...

Data from: Climate and local abundance in freshwater fishes

Jason H. Knouft & Melissa M. Anthony
Identifying factors regulating variation in numbers of individuals among populations across a species' distribution is a fundamental goal in ecology. A common prediction, often referred to as the abundant-centre hypothesis, suggests that abundance is highest near the centre of a species' range. However, because of the primary focus on the geographical position of a population, this framework provides little insight into the environmental factors regulating local abundance. While range-wide variation in population abundance associated with...

Data from: Health insurance coverage with or without a nurse-led task shifting strategy for hypertension control: a pragmatic cluster randomized trial in Ghana

Gbenga Ogedegbe, Jacob Plange-Rhule, Joyce Gyamfi, William Chaplin, Michael Ntim, Kingsley Apusiga, Juliet Iwelunmor, Kwasi Yeboah Awudzi, Kofi Nana Quakyi, Jazmin N. Mogavero, Kiran Khurshid, Bamidele Tayo & Richard Cooper
Rationale: Poor access to care and physician shortage are major barriers to hypertension control in sub-Saharan Africa. Implementation of evidence-based systems-level strategies targeted at these barriers are lacking. Objective: To evaluate the comparative effectiveness of provision of health insurance coverage (HIC) alone versus a nurse-led task-shifting strategy for hypertension control (TASSH) plus HIC on systolic BP reduction among patients with uncontrolled hypertension in Ghana. Methods and Findings: Using a pragmatic cluster-randomized trial, 32 community health...

Position-dependent arm dyskinesia due to severe craniocervical malformation

Francisco de Assis Aquino Gondim, José Arnaldo Mota Arruda, David Nunes de Lima & Florian P. Thomas
Spinal-generated movement disorders are a complex group of medical conditions, frequently misdiagnosed, originating in the spinal cord or from combined peripheral and central nervous system involvement. In this case report, we describe a novel form of position-dependent dyskinesia due to severe craniocervical malformation. An 83-year-old woman with basilar invagination at the C2 vertebra above the line of Chamberlain, occipitocervical lordosis, platybasia with a short clivus, ankylosis of the C1–C2 complex and fusion of the C1...

Analysis of mRNA‑lncRNA and mRNA‑lncRNA-pathway co‑expression networks based on WGCNA in developing pediatric sepsis

Xiaojuan Zhang, Yuqing Cui, Xianfei Ding, Shaohua Liu, Bing Han, Xiaoguang Duan, Haibo Zhang & Tongwen Sun
Pediatric sepsis is a great threat to death worldwide. However, the pathogenesis has not been clearly understood until now in sepsis. This study identified differentially expressed mRNAs and lncRNAs based on Gene Expression Omnibus (GEO) database. And the weighted gene co-expression network analysis (WGCNA) was performed to explore co-expression modules associated with pediatric sepsis. Then, Gene Ontology (GO), KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway, mRNA‑lncRNA and mRNA‑lncRNA-pathway co-expression network analysis was conducted in...

Forecasting NDVI in the Galapagos

Noah Charney, Guillaume Bastille-Rousseau, Charles Yackulic, Stephen Blake & James Gibbs
Forecasting ecosystem response to climate change is critical for guiding policy-making but challenging due to: complicated relationships between microclimates and regional climates; species’ responses that are driven by extremes rather than averages; the multifaceted nature of species’ interactions; and the lack of historical analogs to future climates. Given these challenges, even model systems such as the Galapagos Islands, a world-famous biodiversity hotspot and World Heritage Site, lack clear forecasts for future environmental change. Here, we...

Increases in vein length compensate for leaf area lost to lobing in grapevine

Zoë Migicovsky, Joel F. Swift, Zachary Helget, Laura L. Klein, Anh Ly, Matthew Maimaitiyiming, Karoline Woodhouse, Anne Fennell, Misha Kwasniewski, Allison J. Miller, Peter Cousins & Daniel H. Chitwood
There is considerable variation in leaf lobing and leaf size, including among grapevines, some of the most well-studied leaves. We examined the relationship between leaf lobing and leaf size across grapevine populations which varied in extent of leaf lobing. We used homologous landmarking techniques to measure 2,632 leaves across two years in 476 unique, genetically distinct grapevines from 5 biparental crosses which vary primarily in the extent of lobing. We determined to what extent leaf...

Temperature and mating in harvestmen

Kasey Fowler-Finn & Todd Johnson
Temperature impacts a wide range of mating behaviours, particularly in ectothermic organisms that tend to havebody temperatures similar to ambient thermal conditions. Here, we test the effects of thermal variation on precopulatory and copulatory behaviour in the harvester Leiobunum politum Weed 1889, which belongs to the group commonly known as daddy longlegs. We ran single choice mating trials across temperatures commonly experienced in the field during the mating season (18 - 34 °C) across two...

ACPY2 gene polymorphisms on cancer risk: a systematic review and meta-analysis

Xueliang Chang, Zhan Yang, Hu Wang, Yaxuan Wang, Jingdong Li, Yanping Zhang, Zhihai Teng & Zhenwei Han
To provide a comprehensive account of the association of ACYP2 gene polymorphisms with susceptibility to cancer. A literature search for eligible candidate gene studies published before April 20, 2022 was conducted in the PubMed, Medline and Web of Science. The following combinations of main keywords were used: (ACYP2 OR acylphosphatase 2) AND (polymorphism OR mutation OR variation OR SNP OR genotype) AND (cancer OR tumor OR neoplasm OR malignancy OR carcinoma OR adenocarcinoma). Potential sources...

ACPY2 gene polymorphisms on cancer risk: a systematic review and meta-analysis

Xueliang Chang, Zhan Yang, Hu Wang, Yaxuan Wang, Jingdong Li, Yanping Zhang, Zhihai Teng & Zhenwei Han
To provide a comprehensive account of the association of ACYP2 gene polymorphisms with susceptibility to cancer. A literature search for eligible candidate gene studies published before April 20, 2022 was conducted in the PubMed, Medline and Web of Science. The following combinations of main keywords were used: (ACYP2 OR acylphosphatase 2) AND (polymorphism OR mutation OR variation OR SNP OR genotype) AND (cancer OR tumor OR neoplasm OR malignancy OR carcinoma OR adenocarcinoma). Potential sources...

Light environment interacts with visual displays in a species-specific manner in multimodal signaling wolf spiders

Rowan McGinley, James Starrett, Jason Bond & Eileen Hebets
Light availability is highly variable, yet predictable, over various timescales and the light environment is expected to play an important role in the evolution of visual signals. Courtship displays within the wolf spider genus Schizocosa always involve the use of substrate borne vibrations, however, there is substantial variation between species in the use of visual displays. We assessed the impact of light intensity on the courtship of four species of Schizocosa that vary in their...

Healthy Outcomes of Patients with COVID-19 Two Years after the Infection: A Prospective Cohort Study

Dapeng Li, Xuejiao Liao, Zhi Liu, Zhenghua Ma, Jingke Dong, Guoqin Zheng, Mei Zi, Fang Wang, Qing He, Guobao Li, Zheng Zhang & Lei Liu
The long-term effect of coronavirus disease 2019 (COVID-19) has been rarely known. This study aimed to investigate healthy outcomes of COVID-19 survivors up to 2 years after the infection. A total of 155 COVID-19 patients, who were discharged from Shenzhen Third People's Hospital from February 2020 to April 2020, were enrolled and followed up until March 4, 2022. COVID-19 survivors received questionnaires of long COVID symptoms and psychological symptoms, pulmonary function tests, chest computed tomography...

Healthy outcomes of patients with COVID-19 two years after the infection: a prospective cohort study

Dapeng Li, Xuejiao Liao, Zhi Liu, Zhenghua Ma, Jingke Dong, Guoqin Zheng, Mei Zi, Fang Wang, Qing He, Guobao Li, Zheng Zhang & Lei Liu
The long-term effect of coronavirus disease 2019 (COVID-19) has been rarely known. This study aimed to investigate healthy outcomes of COVID-19 survivors up to 2 years after the infection. A total of 155 COVID-19 patients, who were discharged from Shenzhen Third People's Hospital from February 2020 to April 2020, were enrolled and followed up until March 4, 2022. COVID-19 survivors received questionnaires of long COVID symptoms and psychological symptoms, pulmonary function tests, chest computed tomography...

Reconsidering T component of cancer staging for T3/T4 non-small-cell lung cancer with additional nodule

Fang Wang, Hang Su, Haoran E, Likun Hou, Minglei Yang, Long Xu, Jiani Gao, Mengmeng Zhao, Junqi Wu, Jiajun Deng, Xiaofeng Xie, Yifan Zhong, Yingze Li, Tingting Wang, Chunyan Wu, Dong Xie & Chang Chen
Background:Non-small-cell lung cancer (NSCLC) with additional nodule(s) located in the same lobe or ipsilateral different lobe were designated as T3 and T4, respectively, which was merely defined by anatomical location of additional nodule(s), regardless of other prognostic factors.Methods:A total of 4711 patients with T1-4, N0-2, M0 NSCLC undergoing complete resection were identified between 2009 and 2014, including 145 patients with additional nodule(s) in the same lobe (T3-Add) and 174 patients with additional tumor nodule(s) in...

Global variation in isolated posterior cruciate ligament reconstruction

Derrick M. Knapik, Varun Gopinatth, Garrett R. Jackson, Jorge Chahla, Matthew V. Smith, Matthew J. Matava & Robert H. Brophy
Abstract Purpose In the setting of persistent instability or failed non-operative management, surgical reconstruction is commonly recommended for isolated posterior cruciate ligament (PCL) tears. The purpose of this study was to systematically review published studies to evaluate regional variation in the epidemiology of and surgical approaches to primary, isolated PCL reconstruction. Methods A systematic review was performed in June 2022 to identify studies examining operative techniques during primary, isolated PCL reconstruction. Collected variables consisted of...

sj-docx-1-jmh-10.1177_15579883221135764 – Supplemental material for Men’s Preconception Health and Fertility Intentions: A Latent Class Analysis Approach

Adaobi Anakwe, Rhonda BeLue, Hong Xian & Pamela Xaverius
Supplemental material, sj-docx-1-jmh-10.1177_15579883221135764 for Men’s Preconception Health and Fertility Intentions: A Latent Class Analysis Approach by Adaobi Anakwe, Rhonda BeLue, Hong Xian and Pamela Xaverius in American Journal of Men's Health

Additional file 4 of SWI/SNF complex gene variations are associated with a higher tumor mutational burden and a better response to immune checkpoint inhibitor treatment: a pan-cancer analysis of next-generation sequencing data corresponding to 4591 cases

Yue Li, Xinhua Yang, Weijie Zhu, Yuxia Xu, Jiangjun Ma, Caiyun He & Fang Wang
Additional file 4: Table S1. Synthetic lethal interactive pairs and chemical inhibitors involving SWI/SNF members.

Development and validation of a combined model based on dual-sequence MRI radiomics for predicting the efficacy of high-intensity focused ultrasound ablation for hysteromyoma

Shize Qin, Yu Jiang, Fang Wang, Lingling Tang & Xiaohua Huang
To determine the value of dual-sequence magnetic resonance imaging (MRI)-based radiomics in predicting the efficacy of high-intensity focused ultrasound (HIFU) ablation for hysteromyoma. A total of 142 patients with 172 hysteromyomas (95 hysteromyomas from the sufficient ablation group, and 77 hysteromyomas from the insufficient ablation group) were enrolled in the study. The clinical–radiological model was constructed with independent clinical–radiological risk factors, the radiomics model was constructed based on the optimal radiomics features of hysteromyoma from...

Data from: Single nucleotide polymorphism discovery via genotyping by sequencing to assess population genetic structure and recurrent polyploidization in Andropogon gerardii

Christine McAllister, Allison J. Miller & Christine A. McAllister
Premise of the study. Autopolyploidy, genome duplication within a single lineage, can result in multiple cytotypes within a species. Geographic distributions of cytotypes may reflect the evolutionary history of autopolyploid formation and subsequent population dynamics including stochastic (drift) and deterministic (differential selection among cytotypes) processes. Here, we used a population genomic approach to investigate whether autopolyploidy occurred once or multiple times in Andropogon gerardii, a widespread, North American grass with two predominant cytotypes. Methods. Genotyping-by-sequencing...

Altered expression levels of miR-144-3p and ATP1B2 are associated with schizophrenia

Bo Pan, Yuting Wang, Yiwen Shi, Qianzhan Yang, Bing Han, Xiaoli Zhu & Yanqing Liu
Objectives: Schizophrenia is a devastating mental disease. Various microRNAs were proven to be associated with schizophrenia. Altered microRNA-144-3p (miR-144-3p) levels were found in various neurological and psychotic disorders. Beta2-subunit of Na(+)/K(+)-ATPase (ATP1B2) regulates neuronal migration and cell growth during brain development through the PI3K/Akt/mTOR pathway. The present study explored the associations of miR-144-3p and ATP1B2 with schizophrenia and their mutual interaction. Methods: A schizophrenic animal model employing repeated MK-801 administration was established and 293 T...

Data for: Evolutionary interactions between thermal ecology and sexual selection

Noah Leith, Kasey Fowler-Finn & Michael Moore
Thermal ecology and mate competition are both pervasive features of ecological adaptation. A surge of recent work has uncovered the diversity of ways in which temperature affects mating interactions and sexual selection. However, the potential for thermal biology and reproductive ecology to evolve together as organisms adapt to their thermal environment has been underappreciated. Here, we develop a series of hypotheses regarding (1) not only how thermal ecology affects mating system dynamics, but also how...

Developmental temperature alters the thermal sensitivity of courtship activity and signal-preference relationships, but not mating rates

Anthony Macchiano, Kasey D. Fowler-Finn, Em Miller, Uchechukwu Agali & Abisiola Ola-Ajose
Mating behaviours are susceptible to novel or stressful thermal conditions, particularly for ectothermic organisms. One way to deal with changes in thermal conditions is to exhibit developmental plasticity, whereby the thermal sensitivity of mating behaviours depend on developmental conditions. We test how developmental temperature affects the thermal sensitivity of courtship behaviour and mating rates, as well as mating signal and preference coupling. We rear treehoppers under two temperature regimes and then test how a range...

An examination of the association between marital status and prenatal mental disorders using linked health administrative data

Asres Bedaso, Jon Adams, Wenbo Peng, Fenglian Xu & David Sibbritt
Abstract Background International research shows marital status impacts the mental health of pregnant women, with prenatal depression and anxiety being higher among non-partnered women. However, there have been few studies examining the relationship between marital status and prenatal mental disorders among Australian women. Methods This is a population-based retrospective cohort study using linked data from the New South Wales (NSW) Perinatal Data Collection (PDC) and Admitted Patients Data Collection (APDC). The cohort consists of a...

Interspecific hybridization and island colonization history, not rarity, most strongly affect the genetic diversity in a clade of Mascarene-endemic trees

Alexander Linan, Christine Edwards, George Schatz, Porter Lowry, Allison Miller & Jean Claude Sevathian
Many factors shape the genetic diversity of island-endemic trees, with important implications for conservation. Oceanic island-endemic lineages undergo an initial founding bottleneck during the colonization process and subsequently accumulate diversity following colonization. Moreover, many island endemics occur in small populations and are further threatened by anthropogenic factors that cause population declines, making them susceptible to losses in genetic diversity through genetic drift, inbreeding, and bottlenecks. However, life-history traits commonly found in trees, such as outcrossing...

Healthy outcomes of patients with COVID-19 two years after the infection: a prospective cohort study

Dapeng Li, Xuejiao Liao, Zhi Liu, Zhenghua Ma, Jingke Dong, Guoqin Zheng, Mei Zi, Fang Wang, Qing He, Guobao Li, Zheng Zhang & Lei Liu
The long-term effect of coronavirus disease 2019 (COVID-19) has been rarely known. This study aimed to investigate healthy outcomes of COVID-19 survivors up to 2 years after the infection. A total of 155 COVID-19 patients, who were discharged from Shenzhen Third People's Hospital from February 2020 to April 2020, were enrolled and followed up until March 4, 2022. COVID-19 survivors received questionnaires of long COVID symptoms and psychological symptoms, pulmonary function tests, chest computed tomography...

Registration Year

  • 2023
    2
  • 2022
    67
  • 2021
    5
  • 2020
    4
  • 2019
    2
  • 2018
    1
  • 2017
    1
  • 2016
    5
  • 2015
    2
  • 2014
    2

Resource Types

  • Dataset
    38
  • Text
    30
  • Collection
    16
  • Image
    6
  • Audiovisual
    5
  • Other
    1

Affiliations

  • Saint Louis University
    96
  • Chinese Academy of Medical Sciences & Peking Union Medical College
    37
  • Jiangsu Province Hospital
    35
  • Second Military Medical University
    35
  • Shanxi Medical University
    33
  • Peking University First Hospital
    33
  • Zhejiang University
    31
  • Beijing University of Chemical Technology
    31
  • Air Force Medical University
    31
  • Guangzhou Medical University
    31