14 Works

Data from: Monoallelic chromatin conformation flanking long-range silenced domains in cancer-derived and normal cells

Domenic Di Paola, John Raelson, Emmanouil Rampakakis, Mark Basik, Maria Zannis-Hadjopoulos & W. Edward C. Bradley
Epigenetic inactivation of chromatin plays an important role in determining cell phenotype in both normal and cancer cells, but our knowledge is still incomplete with respect to any potential monoallelic nature of the phenomenon. We have genotyped DNA isolated from chromatin of two colorectal cancer-derived lines and a culture of normal human intestinal epithelial cells (HIEC), which was immunoprecipitated with antibodies to acetylated vs. methylated histone H3K9, and presented the data as B allele frequency...

Data from: Secondary evolution of a self-incompatibility locus in the Brassicaceae genus Leavenworthia

Sier-Ching Chantha, Adam C. Herman, Adrian E. Platts, Xavier Vekemans & Daniel J. Schoen
Self-incompatibility (SI) is the flowering plant reproductive system in which self pollen tube growth is inhibited, thereby preventing self-fertilization. SI has evolved independently in several different flowering plant lineages. In all Brassicaceae species in which the molecular basis of SI has been investigated in detail, the product of the S-locus receptor kinase (SRK) gene functions as receptor in the initial step of the self pollen-rejection pathway, while that of the S-locus cysteine-rich (SCR) gene functions...

Data from: Genetic structure of the white-footed mouse in the context of the emergence of Lyme disease in southern Québec

Anita Rogic, Nathalie Tessier, Pierre Legendre, François-Joseph Lapointe & Virginie Millien
Microsatellite GenotypesA text file containing all the genotypes (11 loci) usedRogic et al. Microsatellite genotypes.txt

Data from: Two decades of genetic profiling yields first evidence of natal philopatry and long-term fidelity to parturition sites in sharks

Kevin A. Feldheim, Samuel H. Gruber, Joseph D. DiBattista, Elizabeth A. Babcock, Steven A. Kessel, Andrew P. Hendry, Ellen K. Pikitch, Mary V. Ashley & Demian D. Chapman
Sharks are a globally threatened group of marine fishes that often breed in their natal region of origin. There has even been speculation that female sharks return to their exact birthplace to breed (“natal philopatry”), which would have important conservation implications. Genetic profiling of lemon sharks (Negaprion brevirostris) from 20 consecutive cohorts (1993-2012) at Bimini, Bahamas showed that certain females faithfully gave birth at this site for nearly two decades. At least six females born...

Data from: Somatic deleterious mutation rate in a woody plant: estimation from phenotypic data

Daniel J. Schoen, Kyle Bobiwash & Stewart T. Schultz
We conducted controlled crosses in populations of the long-lived clonal shrub, Vaccinium angustifolium (lowbush blueberry) to estimate inbreeding depression and mutation parameters associated with somatic deleterious mutation. Inbreeding depression level was high, with many plants failing to set fruit after self-pollination. We also compared fruit set from autogamous pollinations (pollen collected from within the same inflorescence) to fruit set from geitonogamous pollinations (pollen collected from the same plant but from inflorescences separated by several meters...

Data from: Solving the paradox of stasis: squashed stabilizing selection and the limits of detection

Benjamin C. Haller & Andrew P. Hendry
Despite the potential for rapid evolution, stasis is commonly observed over geological timescales – the so-called “paradox of stasis.” This paradox would be resolved if stabilizing selection were common, but stabilizing selection is infrequently detected in natural populations. We hypothesize a simple solution to this apparent disconnect: stabilizing selection is hard to detect empirically once populations have adapted to a fitness peak. To test this hypothesis, we developed an individual-based model of a population evolving...

Data from: Taller plants have lower rates of molecular evolution

Robert Lanfear, Simon Y. W. Ho, T. Jonathan Davies, Angela T. Moles, Lonnie Aarssen, Nathan G. Swenson, Laura Warman, Amy E. Zanne & Andrew P. Allen
Rates of molecular evolution have a central role in our understanding of many aspects of species’ biology. However, the causes of variation in rates of molecular evolution remain poorly understood, particularly in plants. Here we show that height accounts for about one-fifth of the among-lineage rate variation in the chloroplast and nuclear genomes of plants. This relationship holds across 138 families of flowering plants, and when accounting for variation in species richness, temperature, ultraviolet radiation,...

Data from: Glaciation as an historical filter of below-ground biodiversity

Jerome Mathieu & T. Jonathan Davies
Aim: The latitudinal gradient in species richness is one of the most studied biodiversity patterns. Here we explore a north–south gradient in earthworm diversity, and evaluate the importance of current and historical filters in shaping the distribution of present-day below-ground species richness. Location: France. Methods: Using high-resolution data on earthworm distributions across France, we document the latitudinal gradients in alpha (α), beta (β) and gamma (γ) diversity. We relate these gradients to species' traits, taxonomic...

Data from: The incidental response to uniform natural selection

Graham Bell
When populations are exposed to novel conditions of growth they often become adapted to a similar extent, and at the same time evolve some degree of impairment in their original environment. They may also come to vary widely with respect to characters which are uncorrelated with fitness, as the result of chance genetic associations among the founders, when these are a small sample from a large and variable ancestral population. I report an experiment in...

Data from: Evolutionary inferences from the analysis of exchangeability

Andrew P. Hendry, Renaud Kaeuffer, Erika Crispo, Catherine Lynn Peichel & Daniel I. Bolnick
Evolutionary inferences are usually based on statistical models that compare mean genotypes and phenotypes (or their frequencies) among populations. An alternative is to use the actual distribution of genotypes and phenotypes to infer the “exchangeability” of individuals among populations. We illustrate this approach by using discriminant functions on principal components to classify individuals among paired lake and stream populations of threespine stickleback in each of six independent watersheds. Classification based on neutral and non-neutral microsatellite...

Data from: Density triggers maternal hormones that increase adaptive offspring growth in a wild mammal

Ben Dantzer, Amy E. M. Newman, Rudy Boonstra, Rupert Palme, Stan Boutin, Murray M. Humphries & Andrew G. McAdam
Spruce cone and squirrel density dataData used to investigate how previous year spruce cones and food-supplementation affected red squirrel density. All data collected in Kluane, Yukon, Canada.Spruce cone and density data.csvTable S2 Results - neonate mass and growth rateData used for results shown in Table 2. Only neonate mass and offspring growth data. All data collected in Kluane, Yukon, Canada.Table S2 - neonate mass and growth rate.csvTable S2-S3 ResultsData for results shown in Table S2...

Data from: Hybridization between genetically modified Atlantic salmon and wild brown trout reveals novel ecological interactions

Krista B. Oke, Peter A. H. Westley, Darek T. R. Moreau & Ian A. Fleming
Interspecific hybridization is a route for transgenes from genetically modified (GM) animals to invade wild populations, yet the ecological effects and potential risks that may emerge from such hybridization are unknown. Through experimental crosses, we demonstrate transmission of a growth hormone transgene via hybridization between a candidate for commercial aquaculture production, GM Atlantic salmon (Salmo salar), and closely related wild brown trout (S. trutta). Transgenic hybrids were viable and grew more rapidly than transgenic salmon...

Data from: Long-term culture at elevated atmospheric CO2 fails to evoke specific adaptation in seven freshwater phytoplankton species

Etienne Low-Décarie, Graham Bell, Gregor F. Fussmann, Mark D. Jewell & E. Low-Decarie
The concentration of CO2 in the atmosphere is expected to double by the end of the century. Experiments have shown that this will have important effects on the physiology and ecology of photosynthetic organisms, but it is still unclear if elevated CO2 will elicit an evolutionary response in primary producers that causes changes in physiological and ecological attributes. In this study, we cultured lines of seven species of freshwater phytoplankton from three major groups at...

Data from: Stochastic environmental fluctuations drive epidemiology in experimental host–parasite metapopulations

Alison B. Duncan, Andrew Gonzalez & Oliver Kaltz
Environmental fluctuations are important for parasite spread and persistence. However, the effects of the spatial and temporal structure of environmental fluctuations on host–parasite dynamics are not well understood. Temporal fluctuations can be random but positively autocorrelated, such that the environment is similar to the recent past (red noise), or random and uncorrelated with the past (white noise). We imposed red or white temporal temperature fluctuations on experimental metapopulations of Paramecium caudatum, experiencing an epidemic of...

Registration Year

  • 2013

Resource Types

  • Dataset


  • McGill University
  • University of Washington
  • Fred Hutchinson Cancer Research Center
  • The University of Texas at Austin
  • Université de Sherbrooke
  • Field Museum of Natural History
  • Department of Plant Biology
  • University of Alberta
  • University of Montreal
  • Australian National University