539 Works

Additional file 2 of Clinical management guidelines for Friedreich ataxia: best practice in rare diseases

Louise A. Corben, Veronica Collins, Sarah Milne, Jennifer Farmer, Ann Musheno, David Lynch, Sub Subramony, Massimo Pandolfo, Jörg B. Schulz, Kim Lin & Martin B. Delatycki
Additional file 2. Recommendations review survey.

Additional file 1 of Investigation of the causal relationship between ALS and autoimmune disorders: a Mendelian randomization study

Paria Alipour, Konstantin Senkevich, Jay P. Ross, Dan Spiegelman, Despoina Manousaki, Patrick A. Dion & Guy A. Rouleau
Additional file 1: Figure S1. Funnel plots and LOO plots which detect outlier SNPs in RA and CD. Figure S2. Scatter plots showing the effect of liability to ALS on risk of autoimmune disorders. Table S1. Sensitivity analysis, heterogeneity, and pleiotropy, investigating MR assumption violation. Table S2. Sensitivity analysis, heterogeneity, and pleiotropy, investigating MR reverse assumption violation. Code used in this study includes all the code used to produce all the results in this paper.

Additional file 2 of Patient satisfaction with e-oral health care in rural and remote settings: a systematic review

Elham Emami, Hermina Harnagea, Richa Shrivastava, Motahareh Ahmadi & Nicolas Giraudeau
Additional file 2. Appendix 2. Search methodology.

Additional file 4 of Patient satisfaction with e-oral health care in rural and remote settings: a systematic review

Elham Emami, Hermina Harnagea, Richa Shrivastava, Motahareh Ahmadi & Nicolas Giraudeau
Additional file 4. The Risk Of Bias In Non-randomized Studies–of Interventions (ROBINS-I) assessment tool.

Additional file 4 of A longitudinal census of the bacterial community in raw milk correlated with Staphylococcus aureus clinical mastitis infections in dairy cattle

Soyoun Park, Dongyun Jung, Ianina Altshuler, Daryna Kruban, Simon Dufour & Jennifer Ronholm
Additional file 4: Table S3. Etiological agents isolated from clinical mastitic milk samples

Additional file 6 of A longitudinal census of the bacterial community in raw milk correlated with Staphylococcus aureus clinical mastitis infections in dairy cattle

Soyoun Park, Dongyun Jung, Ianina Altshuler, Daryna Kruban, Simon Dufour & Jennifer Ronholm
Additional file 6: Table S5. Bacterial species/strains and their relative abundance (%) found in three milk samples from the shotgun metagenomic sequneces

A novel nomogram to stratify quality of life among advanced cancer patients with spinal metastatic disease after examining demographics, dietary habits, therapeutic interventions, and mental health status

Yue Li, Ze Long, Xiuju Wang, Mingxing Lei, Chunzi Liu, Xiaolin Shi & Yaosheng Liu
Abstract Background It would be very helpful to stratify patients and direct patient selection if risk factors for quality of life were identified in a particular population. Nonetheless, it is still challenging to forecast the health-related quality of life among individuals with spinal metastases. The goal of this study was to stratify patient’s populations for whom the assessment of quality of life should be encouraged by developing and validating a nomogram to predict the quality...

Phenotypic stability in scalar calcium of freshwater fish across a wide range of aqueous calcium availability in nature

Sarah Sanderson, Alison Derry & Andrew Hendry
Spatial environmental gradients can promote adaptive differences among conspecific populations as a result of local adaptation or phenotypic plasticity. Such divergence can be opposed by various constraints, including gene flow, limited genetic variation, temporal fluctuations, or developmental constraints. We focus on the constraint that can be imposed when some populations are found in locations characterized by low levels of an essential nutrient. We use scales of wild fish to investigate phenotypic effects of spatial variation...

sj-pdf-1-smm-10.1177_09622802221139233 - Supplemental material for Standard error estimation in meta-analysis of studies reporting medians

Sean McGrath, Stephan Katzenschlager, Alexandra J Zimmer, Alexander Seitel, Russell Steele & Andrea Benedetti
Supplemental material, sj-pdf-1-smm-10.1177_09622802221139233 for Standard error estimation in meta-analysis of studies reporting medians by Sean McGrath, Stephan Katzenschlager, Alexandra J Zimmer, Alexander Seitel, Russell Steele and Andrea Benedetti in Statistical Methods in Medical Research

Aetiology of severe community acquired pneumonia in adults identified by combined detection methods: a multi-centre prospective study in China

Jieming Qu, Jing Zhang, Yu Chen, Yi Huang, Yusang Xie, Min Zhou, Yuping Li, Dongwei Shi, Jinfu Xu, Qiuyue Wang, Bei He, Ning Shen, Bin Cao, Danyang She, Yi Shi, Xin Su, Hua Zhou, Hong Fan, Feng Ye, Qiao Zhang, Xinlun Tian & Guoxiang Lai
Severe Community Acquired Pneumonia (SCAP) challenges public health globally. Considerable improvements in molecular pathogen testing emerged in the last few years. Our prospective study combinedly used traditional culture, antigen tests, PCR and mNGS in SCAP pathogen identification with clinical outcomes. From June 2018 to December 2019, we conducted a multi-centre prospective study in 17 hospitals of SCAP patients within 48 hours of emergency room stay or hospitalization in China. All clinical data were uploaded into...

Aetiology of severe community acquired pneumonia in adults identified by combined detection methods: a multi-centre prospective study in China

Jieming Qu, Jing Zhang, Yu Chen, Yi Huang, Yusang Xie, Min Zhou, Yuping Li, Dongwei Shi, Jinfu Xu, Qiuyue Wang, Bei He, Ning Shen, Bin Cao, Danyang She, Yi Shi, Xin Su, Hua Zhou, Hong Fan, Feng Ye, Qiao Zhang, Xinlun Tian & Guoxiang Lai
Severe Community Acquired Pneumonia (SCAP) challenges public health globally. Considerable improvements in molecular pathogen testing emerged in the last few years. Our prospective study combinedly used traditional culture, antigen tests, PCR and mNGS in SCAP pathogen identification with clinical outcomes. From June 2018 to December 2019, we conducted a multi-centre prospective study in 17 hospitals of SCAP patients within 48 hours of emergency room stay or hospitalization in China. All clinical data were uploaded into...

Alginate-based aerogels as wound dressings for efficient bacterial capture and enhanced antibacterial photodynamic therapy

Ning Guo, Yu Xia, Weishen Zeng, Jia Chen, Quanxin Wu, Yaxin Shi, Guoying Li, Zhuoyi Huang, Guanhai Wang & Yun Liu
The development of novel wound dressings, such as aerogels, with rapid hemostasis and bactericidal capacities for pre-hospital care is necessary. To prevent the occurrence of bacterial resistance, antibacterial photodynamic therapy (aPDT) with broad-spectrum antibacterial ability and negligible bacterial resistance has been intensively studied. However, photosensitizers often suffer from poor water solubility, short singlet oxygen (1O2) half-life and restricted 1O2 diffusion distance. Herein, sodium alginate was covalently modified by photosensitizers and phenylboronic acid, and cross-linked by...

Recovery of phosphorus from wastewater: A review based on current phosphorous removal technologies

Yulin Zheng, Yongshan Wan, Yue Zhang, Jinsheng Huang, Yicheng Yang, Daniel C. W. Tsang, Hailong Wang, Hao Chen & Bin Gao
Phosphorus (P) as an essential nutrient for life sustains the productivity of food systems; yet misdirected P often accumulates in wastewater and triggers water eutrophication if not properly treated. Although technologies have been developed to remove P, little attention has been paid to the recovery of P from wastewater. This work provides a comprehensive review of the state-of-the-art P removal technologies in the science of wastewater treatment. Our analyses focus on the mechanisms, removal efficiencies,...

KLF5-mediated aquaporin 3 activated autophagy to facilitate cisplatin resistance of gastric cancer

Xudong Dai, Yong Chen, Ning Chen, Jin Dou, Haiwen Zhuang, Jian Wang, Xin Zhao, Xiaoyu Zhang & Haijian Zhao
Resistance to chemotherapeutic drugs limits the control of gastric cancer (GC) development. The study intended to probe into the mechanism of aquaporin 3 (AQP3) on the chemoresistance of GC. Cisplatin (CDDP)-resistant cells were constructed. Parental AGS and HGC-27 cells and their respective CDDP-resistant cells were transfected with AQP3 overexpression plasmid, AQP3 short hairpin RNA (sh-AQP3) and sh-Kruppel-like factor 5 (shKLF5). The expressions of AQP3 and factors related to autophagy (LC3 I, LC3 II, Atg5, Beclin-1,...

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