Data from: REM sleep stabilizes hypothalamic representation of feeding behavior

Lukas T. Oesch, Mary Gazea, Thomas C. Gent, Mojtaba Bandarabadi, Carolina Gutierrez Herrera & Antoine R. Adamantidis
During rapid eye movement (REM) sleep, behavioral unresponsiveness contrasts strongly with intense brain-wide neural network dynamics. Yet, the physiological functions of this cellular activation remain unclear. Using in vivo calcium imaging in freely behaving mice, we found that inhibitory neurons in the lateral hypothalamus (LHvgat) show unique activity patterns during feeding that are reactivated during REM, but not NREM, sleep. REM sleep specific optogenetic silencing of LHvgat cells induced a re-organization of these activity patterns...

Registration Year

  • 2020

Resource Types

  • Dataset


  • University Hospital of Bern