4 Works

Data from: Within-host competition and drug resistance in the human malaria parasite Plasmodium falciparum

Mary Bushman, Lindsay Morton, Nancy Duah, Neils Quashie, Benjamin Abuaku, Kwadwo Koram, Pedro Dimbu, Mateusz Plucinski, Julie Gutman, Peter Lyaruu, Steven Kachur, Jacobus De Roode, Venkatachalam Udhayakumar, Jacobus C. De Roode, S. Patrick Kachur & Kwadwo A. Koram
Infections with the malaria parasite Plasmodium falciparum typically comprise multiple strains, especially in high-transmission areas where infectious mosquito bites occur frequently. However, little is known about the dynamics of mixed-strain infections, particularly whether strains sharing a host compete or grow independently. Competition between drug-sensitive and drug-resistant strains, if it occurs, could be a crucial determinant of the spread of resistance. We analyzed 1,341 P. falciparum infections in children from Angola, Ghana, and Tanzania and found...

Data from: Genetic and paleomodelling evidence of the population expansion of the cattle egret Bubulcus ibis in Africa during the climatic oscillations of the Late Pleistocene

Carlos Congrains, Antônio F. Carvalho, , Graeme S. Cumming, Dominic A. W. Henry, Shiiwua A. Manu, Jacinta Abalaka, Cristiano D. Rocha, Moussa S. Diop, Joãozinho Sá, Hamilton Monteiro, Lars H. Holbech, Francis Gbogbo & Silvia N. Del Lama
Increasing aridity during glacial periods produced the retraction of forests and the expansion of arid and semi-arid environments in Africa, with consequences for birds. Cattle egret (Bubulcus ibis) is a dispersive species that prefers semiarid environments and requires proximity to bodies of water. We expected that climatic oscillations led to the expansion of the range of the cattle egret during arid periods, such as the Last Maximum Glacial (LGM) and contraction of distribution during the...

Data from: Cardiovascular disease risk factors in Ghana during the rural-to-urban transition: a cross-sectional study

Nuri Kodaman, Melinda C. Aldrich, Rafal Sobota, Folkert Asselbergs, Kwabena Poku, Nancy J. Brown, Jason H. Moore, Scott M. Williams, Folkert W. Asselbergs & Kwabena A. Poku
Populations in sub-Saharan Africa are shifting from rural to increasingly urban. Although the burden of cardiovascular disease is expected to increase with this changing landscape, few large studies have assessed a wide range of risk factors in urban and rural populations, particularly in West Africa. We conducted a cross-sectional, population-based survey of 3317 participants from Ghana (≥18 years old), of whom 2265 (57% female) were from a mid-sized city (Sunyani, population ~250,000) and 1052 (55%...

Data from: Seasonality and locality affect the diversity of Anopheles gambiae and Anopheles coluzzii midgut microbiota from Ghana.

Jewelna Akorli, Mathilde Gendrin, Nana Adjoa P. Pels, Dorothy Yeboah-Manu, George K. Christophides & Michael D. Wilson
Symbiotic bacteria can have important implications in the development and competence of disease vectors. In Anopheles mosquitoes, the composition of the midgut microbiota is largely influenced by the larval breeding site, but the exact factors shaping this composition are currently unknown. Here, we examined whether the proximity to urban areas and seasons have an impact on the midgut microbial community of the two major malaria vectors in Africa, An. coluzzii and An. gambiae. Larvae and...

Registration Year

  • 2016

Resource Types

  • Dataset


  • University of Ghana
  • University of Pennsylvania
  • Federal University of São Carlos
  • University College London
  • Emory University
  • University of Cape Town
  • Vanderbilt University School of Medicine
  • Centers for Disease Control and Prevention
  • James Cook University
  • Ifakara Health Institute