Short telomeres drive pessimistic judgment bias in zebrafish

Rui Oliveira, Felipe Espigares, Diana Abad, Miguel Godinho-Ferreira & Susana Varela
The role of telomerase reverse transcriptase (TERT) has been widely investigated in the contexts of aging and age-related diseases. Interestingly, decreased telomerase activities (and accelerated telomere shortening) have also been reported in patients with emotion-related disorders, opening the possibility for subjective appraisal of stressful stimuli playing a key role in stress-driven telomere shortening. In fact, patients showing a pessimistic judgment bias have shorter telomeres. However, these evidences in humans are correlational and the causal inference...

Registration Year

  • 2021
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Resource Types

  • Dataset
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Affiliations

  • Institute of Research on Cancer and Aging in Nice
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  • University of Valencia
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  • Instituto Gulbenkian de Ciência
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