Additional file 1: Database S1. The B. glabrata protein database used in the proteomic data analysis.

Additional file 2: Table S1. Statistical analysis of behavioural bioassays. Two-way ANONA method was used to evaluate the significance of the behavioural modifications.

Additional file 2: Table S1. Statistical analysis of behavioural bioassays. Two-way ANONA method was used to evaluate the significance of the behavioural modifications.

Additional file 4: Table S3. A list of the total proteins, unique proteins and corresponding peptides identified resistant B. glabrata with reference to the B. glabrata proteome.

Additional file 8: Table S5. A list of the total proteins, unique proteins and corresponding peptides identified in susceptible B. glabrata SCW with reference to the S. mansoni proteome, and enriched GO terms related to the proteins.

Additional file 9: Table S6. The results of PPIs shown in Fig. 5 and the co-expression data export from STRING to support the PPI of S. mansoni proteins.

Additional file 6: Figure S1. The representative MS/MS spectrum of LTGMAFR, supporting both B. glabrata and S. mansoni glyceraldehyde-3-phosphate dehydrogenase (G3PDH).

Additional file 5: Table S4. A list of the total proteins, unique proteins and corresponding peptides identified in susceptible B. glabrata with reference to the B. glabrata proteome.

Additional file 7: Figure S2. The representative MS/MS of supporting peptides of S. mansoni protein identification.

Abstract Background Schistosomiasis is a harmful neglected tropical disease caused by infection with Schistosoma spp., such as Schistosoma mansoni. Schistosoma must transition within a molluscan host to survive. Chemical analyses of schistosome-molluscan interactions indicate that host identification involves chemosensation, including naïve host preference. Proteomic technique advances enable sophisticated comparative analyses between infected and naïve snail host proteins. This study aimed to compare resistant, susceptible and naïve Biomphalaria glabrata snail-conditioned water (SCW) to identify potential attractants...

Additional file 1: Database S1. The B. glabrata protein database used in the proteomic data analysis.

Additional file 6: Figure S1. The representative MS/MS spectrum of LTGMAFR, supporting both B. glabrata and S. mansoni glyceraldehyde-3-phosphate dehydrogenase (G3PDH).

Abstract Background Schistosomiasis is a harmful neglected tropical disease caused by infection with Schistosoma spp., such as Schistosoma mansoni. Schistosoma must transition within a molluscan host to survive. Chemical analyses of schistosome-molluscan interactions indicate that host identification involves chemosensation, including naïve host preference. Proteomic technique advances enable sophisticated comparative analyses between infected and naïve snail host proteins. This study aimed to compare resistant, susceptible and naïve Biomphalaria glabrata snail-conditioned water (SCW) to identify potential attractants...

Additional file 8: Table S5. A list of the total proteins, unique proteins and corresponding peptides identified in susceptible B. glabrata SCW with reference to the S. mansoni proteome, and enriched GO terms related to the proteins.

Additional file 7: Figure S2. The representative MS/MS of supporting peptides of S. mansoni protein identification.

Additional file 10: Figure S3. The co-expression levels of S. mansoni proteins identified.

Additional file 3: Table S2. A list of the total proteins, unique proteins and corresponding peptides identified in naïve B. glabrata with reference to the B. glabrata proteome.

Additional file 3: Table S2. A list of the total proteins, unique proteins and corresponding peptides identified in naïve B. glabrata with reference to the B. glabrata proteome.