90 Works

Data from: Effect of light-level geolocators on apparent survival of two highly aerial swift species

Michelangelo Morganti, Diego Rubolini, Susanne Akesson, Ana Bermejo, Javier De La Puente, Roberto Lardelli, Felix Liechti, Giovanni Boano, Erika Tomassetto, Mauro Ferri, Mario Caffi, Nicola Saino & Roberto Ambrosini
Light-level geolocators are currently widely used to track the migration of small-sized birds, but their potentially detrimental effects on survival of highly aerial species have been poorly investigated so far. We recorded capture-recapture histories of 283 common swifts Apus apus and 107 pallid swifts Apus pallidus breeding in 14 colonies in Italy, Spain, Sweden and Switzerland that were deployed with 10 different types of geolocators (‘geolocator birds’), and compared their survival with that of, respectively,...

Data from: Factors associated with first- versus second-generation long-acting antipsychotics prescribed under ordinary clinical practice in Italy

Giovanni Ostuzzi, Maria Angela Mazzi, Samira Terlizzi, Federico Bertolini, Andrea Aguglia, Francesco Bartoli, Paola Bortolaso, Camilla Callegari, Mariarita Caroleo, Giuseppe Carrà, Mariangela Corbo, Armando D'agostino, Chiara Gastaldon, Claudio Lucii, Fabio Magliocco, Giovanni Martinotti, Michela Nosé, Edoardo Giuseppe Ostinelli, Davide Papola, Marco Piccinelli, Alberto Piccoli, Marianna Purgato, Tommaso Tabacchi, Giulia Turrini, Mirella Ruggeri … & Armando D’Agostino
Background. For many years, long-acting intramuscular (LAI) antipsychotics have been prescribed predominantly to chronic and severe patients, as a last resort when other treatments failed. Recently, a broader and earlier use of LAIs, particularly second-generation LAIs, has been emphasized. To date, few studies attempted to frame how this change in prescribing took place in real-world practice. Therefore, this study aimed to describe the clinical features of patients prescribed with LAIs, and to explore possible prescribing...

Data from: Out of the Mediterranean? post-glacial colonisation pathways varied among cold-water coral species

Joana Boavida, Ronan Becheler, Marvin Choquet, Norbert Frank, Marco Taviani, Jean-Francois Bourillet, Anne-Leila Meistertzheim, Anthony Grehan, Alessandra Savini & Sophie Arnaud-Haond
Aim. To infer cold-water corals' post-glacial phylogeography and assess the role of Mediterranean Sea glacial refugia as origins for the recolonisation of the northeastern Atlantic Ocean. Location. Northeastern Atlantic Ocean and Mediterranean Sea. Taxon. Lophelia pertusa, Madrepora oculata. Methods. We sampled cold-water corals using remotely operated vehicles and one sediment core for coral and sediment dating. We characterized spatial genetic patterns (microsatellites and a nuclear gene fragment) using networks, clustering and measures of genetic differentiation....

Data from: Unveiling the food webs of tetrapods across Europe through the prism of the Eltonian niche

Louise O'Connor, Laura J. Pollock, João Braga, Gentile Francesco Ficetola, Alessandro Montemaggiori, Luigi Maiorano, Wilfried Thuiller, Marc Ohlmann & Camille Martinez-Almoyna
Aim Despite the recent calls on integrating the interaction networks into the study of large‐scale biodiversity patterns, we still lack a basic understanding of the functional characteristics of large interaction networks and how they are structured across environments. Here, building on recent advances in network science around the Eltonian niche concept, we aim to characterize the trophic groups in a large food web, and understand how these trophic groups vary across space. Location Europe and...

Razza e istruzione. Le leggi anti-ebraiche del 1938

MARINA CALLONI

Safe and effective off-the-shelf immunotherapy based on CAR.CD123-NK cells for the treatment of acute myeloid leukaemia

Simona Caruso, Biagio De Angelis, Francesca Del Bufalo, Roselia Ciccone, Samantha Donsante, Gabriele Volpe, Simona Manni, Marika Guercio, Michele Pezzella, Laura Iaffaldano, Domenico Alessandro Silvestris, Matilde Sinibaldi, Stefano Di Cecca, Angela Pitisci, Enrico Velardi, Pietro Merli, Mattia Algeri, Mariachiara Lodi, Valeria Paganelli, Marta Serafini, Mara Riminucci, Franco Locatelli & Concetta Quintarelli
Abstract Background Paediatric acute myeloid leukaemia (AML) is characterized by poor outcomes in patients with relapsed/refractory disease, despite the improvements in intensive standard therapy. The leukaemic cells of paediatric AML patients show high expression of the CD123 antigen, and this finding provides the biological basis to target CD123 with the chimeric antigen receptor (CAR). However, CAR.CD123 therapy in AML is hampered by on-target off-tumour toxicity and a long “vein-to-vein” time. Methods We developed an off-the-shelf...

NT-ProBNP and mortality across the spectrum of glucose tolerance in the general US population

Stefano Ciardullo, Federico Rea, Rosa Cannistraci, Emanuele Muraca, Silvia Perra, Francesca Zerbini, Andrea Mortara & Gianluca Perseghin
Abstract Background Even though hyperglycemia is a well-known cardiovascular risk factor, the absolute risk of cardiovascular events varies to a great extent within each glycemic category. The aim of this study is to evaluate whether N-terminal pro-B natriuretic peptide (NT-ProBNP) could help identify subjects at higher cardiovascular risk, independently of blood glucose levels. Methods Serum NT-ProBNP levels were measured in 5502 people aged 45–79 years without heart failure from the general population (3380 with normoglycemia,...

Additional file 1 of Ca2+ dysregulation in cardiac stromal cells sustains fibro-adipose remodeling in Arrhythmogenic Cardiomyopathy and can be modulated by flecainide

Angela S. Maione, Pawan Faris, Lara Iengo, Valentina Catto, Luca Bisonni, Francesco Lodola, Sharon Negri, Michela Casella, Anna Guarino, Gianluca Polvani, Marina Cerrone, Claudio Tondo, Giulio Pompilio, Elena Sommariva & Francesco Moccia
Additional file 1: Text. IP3-induced intracellular Ca2+ release and SOCE drive spontaneous Ca2+ oscillations in ACM C-MSC. Fig. S1. Resting [Ca2+]iin C-MSC. Fig. S2. Suramin and MRS-2179 inhibit the spontaneous Ca2+ activity in ACM C-MSC. Fig. S3. CaMKII expression in human-derived C-MSC. Figure S4: SOCE and IP3Rs drive the spontaneous Ca2+ oscillations in ACM C-MSC. Fig. S5. Effect of XeC on spontaneous Ca2+ oscillations in ACM C-MSC. Fig. S6. Contribution of VOCC and reverse-mode NCX...

Additional file 1 of Combining denoising of RNA-seq data and flux balance analysis for cluster analysis of single cells

Bruno G. Galuzzi, Marco Vanoni & Chiara Damiani
Additional file 1. Cell-cycle effect on flux cluster analysis.

From stories about living to living the stories: composing a collective idea of home in an independent living project

ANTONELLA CUPPARI

Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery

Miklosh Bala, Fausto Catena, Jeffry Kashuk, Belinda De Simone, Carlos Augusto Gomes, Dieter Weber, Massimo Sartelli, Federico Coccolini, Yoram Kluger, Fikri M. Abu-Zidan, Edoardo Picetti, Luca Ansaloni, Goran Augustin, Walter L. Biffl, Marco Ceresoli, Osvaldo Chiara, Massimo Chiarugi, Raul Coimbra, Yunfeng Cui, Dimitris Damaskos, Salomone Di Saverio, Joseph M. Galante, Vladimir Khokha, Andrew W. Kirkpatrick, Kenji Inaba … & Ernest E. Moore
Abstract Acute mesenteric ischemia (AMI) is a group of diseases characterized by an interruption of the blood supply to varying portions of the intestine, leading to ischemia and secondary inflammatory changes. If untreated, this process may progress to life-threatening intestinal necrosis. The incidence is low, estimated at 0.09–0.2% of all acute surgical admissions, but increases with age. Although the entity is an uncommon cause of abdominal pain, diligence is required because if untreated, mortality remains...

Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery

Miklosh Bala, Fausto Catena, Jeffry Kashuk, Belinda De Simone, Carlos Augusto Gomes, Dieter Weber, Massimo Sartelli, Federico Coccolini, Yoram Kluger, Fikri M. Abu-Zidan, Edoardo Picetti, Luca Ansaloni, Goran Augustin, Walter L. Biffl, Marco Ceresoli, Osvaldo Chiara, Massimo Chiarugi, Raul Coimbra, Yunfeng Cui, Dimitris Damaskos, Salomone Di Saverio, Joseph M. Galante, Vladimir Khokha, Andrew W. Kirkpatrick, Kenji Inaba … & Ernest E. Moore
Abstract Acute mesenteric ischemia (AMI) is a group of diseases characterized by an interruption of the blood supply to varying portions of the intestine, leading to ischemia and secondary inflammatory changes. If untreated, this process may progress to life-threatening intestinal necrosis. The incidence is low, estimated at 0.09–0.2% of all acute surgical admissions, but increases with age. Although the entity is an uncommon cause of abdominal pain, diligence is required because if untreated, mortality remains...

Supplemental Material, sj-pdf-1-ssc-10.1177_08944393211018969 - Smartphone Use and Academic Performance: A Pervasiveness Approach Beyond Addiction

Tiziano Gerosa, Marco Gui & Moritz Büchi
Supplemental Material, sj-pdf-1-ssc-10.1177_08944393211018969 for Smartphone Use and Academic Performance: A Pervasiveness Approach Beyond Addiction by Tiziano Gerosa, Marco Gui and Moritz Büchi in Social Science Computer Review

Smartphone Use and Academic Performance: A Pervasiveness Approach Beyond Addiction

Tiziano Gerosa, Marco Gui & Moritz Büchi
Over the past decade, smartphones have permeated all domains of adolescents’ everyday lives, with research dominated by “smartphone addiction.” This study compares one of the most used measures of smartphone addiction with a new alternative measure, the Smartphone Pervasiveness Scale for Adolescents (SPS-A), which focuses on the frequency of smartphone use at key social and physiological moments of daily life. A sample of 3,289 Italian high school students was used to validate the two constructs...

Body-weight variability and risk of cardiovascular outcomes in patients with type 1 diabetes: a retrospective observational analysis of data from the DCCT/EDIC population

Iulia Petria, Samuel Albuquerque, Gaël Varoquaux, Jill-Jênn Vie, Nicolas Venteclef, Kamel Mohammedi, Ronan Roussel, Marion Camoin, Gianluca Perseghin, Gilberto Velho & Louis Potier
Abstract Background Cardiovascular risk and body-weight management are both emerging challenges of type 1 diabetes care. We evaluated the association between intraindividual variability of body-weight and risk of cardiovascular events in people with type 1 diabetes. Methods We analyzed 1,398 participants from the DCCT/EDIC studies. Five indices of intraindividual variability of body-weight were calculated for each participant taking into account body-weight measures obtained during the DCCT follow-up (average 6 ± 2 years). The Average Successive...

Relationships between global functioning and neuropsychological predictors in subjects at high risk of psychosis or with a recent onset of depression

Letizia Squarcina, Lana Kambeitz-Ilankovic, Carolina Bonivento, Cecilia Prunas, Lucio Oldani, Julian Wenzel, Anne Ruef, Dominic Dwyer, Adele Ferro, Stefan Borgwardt, Joseph Kambeitz, Theresa Katharina Lichtenstein, Eva Meisenzahl, Christos Pantelis, Marlene Rosen, Rachel Upthegrove, Linda A. Antonucci, Alessandro Bertolino, Rebekka Lencer, Stephan Ruhrmann, Raimo R. K. Salokangas, Frauke Schultze-Lutter, Katharine Chisholm, Alexandra Stainton, Stephen J. Wood … & Paolo Brambilla
Psychotic disorders are frequently associated with decline in functioning and cognitive difficulties are observed in subjects at clinical high risk (CHR) for psychosis. In this work, we applied automatic approaches to neurocognitive and functioning measures, with the aim of investigating the link between global, social and occupational functioning, and cognition. 102 CHR subjects and 110 patients with recent onset depression (ROD) were recruited. Global assessment of functioning (GAF) related to symptoms (GAF-S) and disability (GAF-D)....

Data from: Integrative taxonomy at work: DNA barcoding of taeniids harbored by wild and domestic cats

Andrea Galimberti, Daniele F. Romano, Marco Genchi, Daniele Paoloni, Francesca Vercillo, Lolita Bizzarri, Davide Sassera, Claudio Bandi, Claudio Genchi, Bernardino Ragni & Maurizio Casiraghi
In modern taxonomy, DNA barcoding is particularly useful where biometric parameters are difficult to determine or useless due to the poor quality of samples. These situations are frequent in parasitology. Here we present an integrated study, based on both DNA barcoding and morphological analysis, on cestodes belonging to the genus Taenia, for which biodiversity is still largely underestimated. In particular, we characterized cestodes from Italian wildcats (Felis silvestris silvestris), free-ranging domestic cats (F. s. catus)...

Data from: Detecting a hierarchical genetic population structure: the case study of the Fire Salamander (Salamandra salamandra) in Northern Italy

Giulia Pisa, Valerio Orioli, Giulia Spilotros, Elena Fabbri, Ettore Randi & Luciano Bani
The multi-step method here applied in studying the genetic structure of a low dispersal and philopatric species, like the Fire Salamander Salamandra salamandra, was proved to be effective in identifying the hierarchical structure of population living in broadleaved forest ecosystems in Northern Italy. In this study 477 salamander larvae, collected in 28 sampling populations (SPs) in the Prealpine and in the foothill areas of Northern Italy, were genotyped at 16 specie-specific microsatellites. SPs showed a...

Data from: Better-surviving barn swallow mothers produce more and better-surviving sons

Andrea Romano, Alessandra Costanzo, Manuela Caprioli, Marco Parolini, Roberto Ambrosini, Diego Rubolini & Nicola Saino
Sex allocation theory predicts that parents are selected to bias their progeny sex ratio (SR) towards the sex that will benefit the most from parental quality. Because parental quality may differentially affect survival of sons and daughters, a pivotal test of the adaptive value of SR adjustment is whether parents overproduce offspring of the sex that accrue larger fitness advantages from high parental quality. However, this crucial test of the long-term fitness consequences of sex...

Data from: Antipsychotic dose mediates the association between polypharmacy and corrected QT interval

Corrado Barbui, Irene Bighelli, Giuseppe Carrà, Mariasole Castellazzi, Claudio Lucii, Giovanni Martinotti, Michela Nosè, Giovanni Ostuzzi & Giovanni Targher
Antipsychotic (AP) drugs have the potential to cause prolongation of the QT interval corrected for heart rate (QTc). As this risk is dose-dependent, it may be associated with the number of AP drugs concurrently prescribed, which is known to be associated with increased cumulative equivalent AP dosage. This study analysed whether AP dose mediates the relationship between polypharmacy and QTc interval. We used data from a cross-sectional survey that investigated the prevalence of QTc lengthening...

Additional file 3 of miR-146a-5p impairs melanoma resistance to kinase inhibitors by targeting COX2 and regulating NFkB-mediated inflammatory mediators

Elisabetta Vergani, Matteo Dugo, Mara Cossa, Simona Frigerio, Lorenza Di Guardo, Gianfrancesco Gallino, Ilaria Mattavelli, Barbara Vergani, Luca Lalli, Elena Tamborini, Barbara Valeri, Chiara Gargiuli, Eriomina Shahaj, Marina Ferrarini, Elisabetta Ferrero, Macarena Gomez Lira, Veronica Huber, Michele Del Vecchio, Marialuisa Sensi, Biagio Eugenio Leone, Mario Santinami, Licia Rivoltini, Monica Rodolfo & Viviana Vallacchi
Additional file 2: Supplementary Fig. S1. Altered miR-146a expression influences BRAF/MEKi sensitivity and apoptosis in melanoma. A) Boxplots representing IC50 values of 6 matched PLX4032-resistant (R) and sensitive (S) melanoma cell lines to PLX4032 (vemurafenib), BRAFi (dabrafenib), MEKi (trametinib), to the combined treatment BRAF/MEKi, and to sTRAIL-induced apoptosis. B) Inverse correlation between miR-146a expression levels and IC50 values of PLX4032, BRAFi and MEKi in melanoma cell lines (Spearman analysis). C) Forced expression of miR-146a (+m-miR-146a)...

Digital Well-Being – Parental Phubbing (2018)

Marco Gui, Tiziano Gerosa, Luca Pancani & Paolo Riva
Digital Well-Being – Parental Phubbing is a cross-sectional database extracted from the second wave of data collection of the Digital Well-being – Schools project, funded by the University of Milano-Bicocca (Innovation Project Grant). The invitation to take part in this project was extended to all the high school in the territorial areas 23, 27 and 28 of the provinces of Milan and Monza-Brianza (Lombardy region, Northern Italy). At the end of the recruitment process, 18...

Data from: Network-scale effects of invasive species on spatially-structured amphibian populations

Raoul Manenti, Mattia Falaschi, Daniele Delle Monache, Silvio Marta & Francesco Ficetola
Understanding the factors affecting the dynamics of spatially-structured populations (SSP) is a central topic of conservation and landscape ecology. Invasive alien species are increasingly important drivers of the dynamics of native species. However, the impacts of invasives are often assessed at the patch scale, while their effects on SSP dynamics are rarely considered. We used long-term abundance data to test whether the impact of invasive crayfish on subpopulations can also affect the whole SSP dynamics,...

Eutrophic status influences the impact of pesticide mixtures and predation on Daphnia pulex populations

Andreu Rico, Talles Oliveira Dos Anjos, Francesco Polazzo, Alba Arenas-Sánchez, Laura Cherta, Roberto Ascari, Sonia Migliorati & Marco Vighi
Pesticides, nutrients, and ecological stressors such as competition or predation co-occur in freshwater ecosystems impacted by agricultural pollution. The extent to which combinations of these stressors affect aquatic populations and the role of nutrients availability in modulating these responses requires further understanding. In this study, we assessed how pesticides affecting different taxonomic groups and predation influence the response of Daphnia pulex populations under different trophic conditions. An outdoor experiment was designed following a factorial design,...

CORAL REEF RESTORATION MONITORING MANUAL - Maldives

Simone Montano, Federica Siena & Hana Amir

Registration Year

  • 2022
    46
  • 2021
    10
  • 2020
    9
  • 2019
    5
  • 2018
    2
  • 2017
    4
  • 2016
    6
  • 2015
    2
  • 2014
    2
  • 2013
    1

Resource Types

  • Dataset
    33
  • Text
    30
  • Collection
    18
  • Journal Article
    6
  • Book
    1
  • Event
    1
  • Other
    1

Affiliations

  • University of Milano-Bicocca
    90
  • University of Milan
    32
  • University of Pavia
    11
  • University of Verona
    10
  • IRCCS Ospedale San Raffaele
    8
  • Fondazione IRCCS Istituto Nazionale dei Tumori
    8
  • University of Paris
    8
  • Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
    6
  • Catholic University of the Sacred Heart
    6
  • University of Padua
    4