103 Works

Community Strengths and Challenges Related to Opioid Use Disorder in Rural Counties of East Tennessee

Ashlyn Schwartz, Zeruiah V. Buchanan & Laurie Meschke
Introduction: Appalachia, particularly Rural East Tennessee, has been and continues to be disproportionately impacted by opioid use disorder and its many tragic ramifications. Purpose: Community-engaged strategies can inform and support the development of relevant prevention efforts. Hence, people connected to a ten-county rural Appalachian region in East Tennessee were asked to identify and prioritize strengths and challenges related to opioid use disorder (OUD). Methods: Adult community members (n=577) completed a brief survey administered across 11...

Soil nitrogen mediates the effect of distance from climatic center on herbivory rates in a tropical herb

Jacob Moutouama & Orou Gaoue
The center-periphery hypothesis predicts that species are most abundant at the center of their range. Differential herbivory rates between center and periphery populations can explain this variation in species abundance. However, if the geographic center of a species distribution coincides with its ecological optimum, the resource availability hypothesis predicts higher herbivory rates and tolerances at the center compared to the periphery. Biogeographic studies on herbivory have treated these two mechanisms separately, limiting our mechanistic understanding...

Data from: The evolution of sex similarities in social signals: Climatic seasonality is associated with lower sexual dimorphism and greater elaboration of female and male signals in antbirds (Thamnophilidae)

Gabriel Macedo, Rafael S. Marcondes, Cibele Biondo, Gustavo Bravo & Elizabeth Derryberry
Selection on signals that mediate social competition varies with resource availability. Climate regulates resource availability, which may affect the strength of competition and selection on signals. Traditionally, this meant that more seasonal, colder, or dryer – overall harsher – environments should favor the elaboration of male signals under stronger male-male competition, increasing sexual dimorphism. However, females also use signals to compete; thus, harsher environments could strengthen competition and favor elaboration of signals in both sexes,...

Comparative clinical outcome following individualized follitropin delta dosing in Chinese women undergoing ovarian stimulation for in vitro fertilization /intracytoplasmic sperm injection

Rui Yang, Yunshan Zhang, Xiaoyan Liang, Xueru Song, Zhaolian Wei, Jianqiao Liu, Yezhou Yang, Jichun Tan, Qingxue Zhang, Yingpu Sun, Wei Wang, Weiping Qian, Lei Jin, Shuyu Wang, Yang Xu, Jing Yang, Marie Goethberg, Bernadette Mannaerts, Wen Wu, Zugeng Zheng & Jie Qiao
Abstract Background To compare the efficacy and safety of follitropin delta in its individualized fixed-dose regimen with follitropin alfa in a conventional adjustable dosing regimen in Chinese women. Methods This was a subgroup analysis of the randomized, multi-center, assessor-blind, non-inferiority trial (GRAPE) including 759 Chinese women (aged 20–40 years) recruited in 16 reproductive medicine clinics in China. Women were randomized in a 1:1 ratio to be treated with either follitropin delta dose based on anti-Müllerian...

Database of plant-flower visitor interactions from Ireland

Laura Russo, Una Fitzpatrick, Michelle Larkin, Sarah Mullen, Eileen Power, Dara Stanley, Cian White, Aoife O'Rourke & Jane Stout
Beneficial insects provide valuable services upon which we rely, including pollination. Pollinator conservation is a global priority, and a significant concern in Ireland, where over half of extant bee species have declined significantly in recent decades. As flower-visiting insects rely on flowering plants, one way to conserve and promote pollinator populations is to protect high-quality habitat. We analysed the structure of insect-flower interactions from multiple habitat categories in a large database of interactions from Ireland....

A general modeling framework for exploring the impact of individual concern and personal protection on vector-borne disease dynamics

Kimberlyn Roosa & Nina H. Fefferman
Abstract Background As climate variability and extreme weather events associated with climate change become more prevalent, public health authorities can expect to face an expanding spectrum of vector-borne diseases with increasing incidence and geographical spread. Common interventions include the use of larvicides and adulticides, as well as targeted communications to increase public awareness regarding the need for personal protective measures, such as mosquito repellant, protective clothing, and mosquito nets. Here, we propose a simplified compartmental...

Additional file 1 of Multimodality treatment for brain arteriovenous malformation in Mainland China: design, rationale, and baseline patient characteristics of a nationwide multicenter prospective registry

Yu Chen, Heze Han, Li Ma, Ruinan Li, Zhipeng Li, Debin Yan, Haibin Zhang, Kexin Yuan, Ke Wang, Yang Zhao, Yukun Zhang, Weitao Jin, Runting Li, Fa Lin, Xiangyu Meng, Qiang Hao, Hao Wang, Xun Ye, Shuai Kang, Hengwei Jin, Youxiang Li, Dezhi Gao, Shibin Sun, Ali Liu, Shuo Wang … & Yuanli Zhao
Additional file 1: Appendix S1. The complete list of MATCH members and sites.

Additional file 1 of Multimodality treatment for brain arteriovenous malformation in Mainland China: design, rationale, and baseline patient characteristics of a nationwide multicenter prospective registry

Yu Chen, Heze Han, Li Ma, Ruinan Li, Zhipeng Li, Debin Yan, Haibin Zhang, Kexin Yuan, Ke Wang, Yang Zhao, Yukun Zhang, Weitao Jin, Runting Li, Fa Lin, Xiangyu Meng, Qiang Hao, Hao Wang, Xun Ye, Shuai Kang, Hengwei Jin, Youxiang Li, Dezhi Gao, Shibin Sun, Ali Liu, Shuo Wang … & Yuanli Zhao
Additional file 1: Appendix S1. The complete list of MATCH members and sites.

3D-printed short arm casts: reliability, validity, feasibility compared with conventional waterproof fiberglass casts: Supplementary material 1

Joseph Smith, Nicholas DePhillipo, Shannon David, Katelyn Nicolay, Sofia Wentz, Abby Steckler & Connor Westberg
Aim: To evaluate the reliability, validity, and feasibility of 3D-printed short arm casts (SACs) versus conventional casts. Methods: Three raters of varying experience applied two conventional and two 3Dprinted casts to a participant’s dominant wrist to evaluate reliability. Each cast was worn for 24 hours and removed the following day after data collection. Results & conclusion: ICCs demonstrated ‘excellent’ intrarater reliability for clinical effectiveness and patient satisfaction. There were no significant differences between fiberglass and...

Understanding of bacterial lignin extracellular degradation mechanisms by Pseudomonas putida KT2440 via secretomic analysis

Zhangyang Xu, Bo Peng, Reta Birhanu Kitata, Carrie D. Nicora, Karl K. Weitz, Yunqiao Pu, Tujin Shi, John R. Cort, Arthur J. Ragauskas & Bin Yang
Abstract Background Bacterial lignin degradation is believed to be primarily achieved by a secreted enzyme system. Effects of such extracellular enzyme systems on lignin structural changes and degradation pathways are still not clearly understood, which remains as a bottleneck in the bacterial lignin bioconversion process. Results This study investigated lignin degradation using an isolated secretome secreted by Pseudomonas putida KT2440 that grew on glucose as the only carbon source. Enzyme assays revealed that the secretome...

Understanding of bacterial lignin extracellular degradation mechanisms by Pseudomonas putida KT2440 via secretomic analysis

Zhangyang Xu, Bo Peng, Reta Birhanu Kitata, Carrie D. Nicora, Karl K. Weitz, Yunqiao Pu, Tujin Shi, John R. Cort, Arthur J. Ragauskas & Bin Yang
Abstract Background Bacterial lignin degradation is believed to be primarily achieved by a secreted enzyme system. Effects of such extracellular enzyme systems on lignin structural changes and degradation pathways are still not clearly understood, which remains as a bottleneck in the bacterial lignin bioconversion process. Results This study investigated lignin degradation using an isolated secretome secreted by Pseudomonas putida KT2440 that grew on glucose as the only carbon source. Enzyme assays revealed that the secretome...

Additional file 1 of Frequency of occurrence and habitat selection shape the spatial variation in the antibiotic resistome in riverine ecosystems in eastern China

Chunxia Jiang, Haiyang Chen, Hans-Peter Grossart, Quanfa Zhang, Robby Stoks, Yi Zhao, Feng Ju, Wenzhi Liu & Yuyi Yang
Additional file 1: TableS1. The detailed information ofsampling sites. Table S2. The alpha diversity of ARGs in this study. TableS3. The Mantel test between ARGs and bacteria (species) in each habitats. TableS4. The feactures of the network diagram of ARGs and bacterial communitiesin different habitats. Table S5. The Mantel test between ARGs and MGEsin each habitats. Table S5. The Mantel test between ARGs and MGEs in eachhabitats. Table S6. Co-occurrence of ARGs and MGEs on...

Additional file 2 of Frequency of occurrence and habitat selection shape the spatial variation in the antibiotic resistome in riverine ecosystems in eastern China

Chunxia Jiang, Haiyang Chen, Hans-Peter Grossart, Quanfa Zhang, Robby Stoks, Yi Zhao, Feng Ju, Wenzhi Liu & Yuyi Yang
Additional file 2: Fig. S1Number (a) and relative abundance (b) of ARGs detected inriverine ecosystems of eastern China. R represents rhizosphere soil; SBrepresents surface bulk soil (0-20 cm below bulk soil surface); BB represents bottombulk soil (40-60 cm below bulk soil surface); S represents sediment (0-20 cmbelow sediment surface); SR and NR represent rhizosphere soil in the south andnorth, respectively; SSB and NSB represent surface bulk soil (0-20 cm belowbulk soil surface) in the south...

Additional file 2 of Frequency of occurrence and habitat selection shape the spatial variation in the antibiotic resistome in riverine ecosystems in eastern China

Chunxia Jiang, Haiyang Chen, Hans-Peter Grossart, Quanfa Zhang, Robby Stoks, Yi Zhao, Feng Ju, Wenzhi Liu & Yuyi Yang
Additional file 2: Fig. S1Number (a) and relative abundance (b) of ARGs detected inriverine ecosystems of eastern China. R represents rhizosphere soil; SBrepresents surface bulk soil (0-20 cm below bulk soil surface); BB represents bottombulk soil (40-60 cm below bulk soil surface); S represents sediment (0-20 cmbelow sediment surface); SR and NR represent rhizosphere soil in the south andnorth, respectively; SSB and NSB represent surface bulk soil (0-20 cm belowbulk soil surface) in the south...

Additional file 1 of The public health exposome and pregnancy-related mortality in the United States: a high-dimensional computational analysis

E. W. Harville, S.K. Grady, MA Langston, P. J. Juarez, D. Vilda & M. E. Wallace
Additional file 1.

Increasing burden of stroke in China: A systematic review and meta-analysis of prevalence, incidence, mortality, and case fatality

Yang Zhao, Xing Hua, Xinwen Ren, Menglu Ouyang, Chen Chen, Yunke Li, Xiaoya Yin, Peige Song, Xiaoying Chen, Simiao Wu, Lili Song & Craig S Anderson
Background:The epidemiology of stroke is evolving in China as the population undergoes demographic, lifestyle, and economic transitions. An updated review is pertinent to providing feedback on current, and in planning future, prevention and management strategies.Aims:To identify high-quality epidemiological studies for quantifying the prevalence, incidence, mortality, and case fatality for stroke in China.Methods:A search was undertaken across a range of bibliographic databases on 30 November 2021 without time limitation. Assessments were made of the risk of...

Ambient PM2.5 exposure causes cellular senescence via DNA damage, micronuclei formation, and cGAS activation

Tao Wu, Shengmin Xu, Biao Chen, Lingzhi Bao, Jie Ma, Wei Han, An Xu, Kwan Ngok Yu, Lijun Wu & Shaopeng Chen
Ambient PM2.5 is one of the environmental risk factors and was correlated with senescence-related diseases based on the epidemiologic investigation. However, little is known about senescence induced by PM2.5 as well as the underlying mechanisms. In this study, we demonstrated that PM2.5 exposure aggravated cellular senescence in vivo and in vitro, and disrupted micronuclei (MN) played a vital role in this process. Our results suggested that the nuclear envelope (NE) of PM2.5-induced MN was ruptured....

Additional file 1 of Effects of left atrial function on pulmonary arterial pressure in acute myocardial infarction, hypertrophic and dilated cardiomyopathy

Minjeong Kim, Hyemoon Chung, In-Soo Kim, Chul Hwan Park, Se-Joong Rim & Eui-Young Choi
Additional file 1. Table S1. Comparison of clinical, echocardiographic and CMR findings between left anterior descending coronary artery (LAD) and non-LAD territory acute myocardial infarction. Table S2. Relationship between average extracellular volume fraction of left ventricle and left atrial anatomic and functional parameters.Table S3. Differential contribution of the left atrial volume, function, and left ventricular fibrosis on the pulmonary arterial systolic pressure in reperfused acute myocardial infarction. Table S4. Relationship between pulmonary arterial systolic pressure...

Altitude-mediated soil properties, not geography or climatic distance, explain the distribution of a tropical endemic herb

Jacob Moutouama & Orou Gaoue
Understanding the ecological processes that govern species’ range margins is a fundamental question in ecology with practical implications in conservation biology. The centre-periphery hypothesis (CPH) predicts that organisms have higher abundance at the centre of their geographic range. However, most tests of the CPH often used raster data, assuming that climatic conditions are consistent across one square km. This assumption is not always justified, particularly for species that live in mountainous regions where climatic conditions...

Chloroplast genome of the invasive Pyrus calleryana

Marcin Nowicki, Matthew Huff, Margaret Staton & Robert Trigiano
The complete chloroplast genome of Pyrus calleryana (BioSample SAMC013142) was developed by de novo assembly from whole-genome sequencing data. Reference-guided (P. phaeocarpa) read mapping and assembly were followed by annotation and phylogenetic comparisons. The Pyrus calleryana chloroplast genome of 159,965 bp in length (36,56% of GC content) represents a classical quadripartite architecture, with two inverted repeats regions (IRs; each 26,392 bp in length) separating the large single-copy region (LSC; 87,942 bp) and the small single-copy...

MALDI-MS raw files of primary human lung cancer samples, lung cancer patient derived xenografts and lung cancer mouse models

Caterina Bartolacci, Cristina Andreani, A. Colleen Crouch & Pier Paolo Scaglioni
Human primary lung cancer samples, patient derived lung cancer xenografts and lung tumors from the TetO-KRASG12D mouse model were analyzed using MALDI-MS. We determined the spatial distribution and relative abundance of lipids of interest.

DateLife: leveraging databases and analytical tools to reveal the dated Tree of Life

Luna Luisa Sanchez Reyes, Emily Jane McTavish & Brian O'Meara
Achieving a high-quality reconstruction of a phylogenetic tree with branch lengths proportional to absolute time (chronogram) is a difficult and time-consuming task. But the increased availability of fossil and molecular data, and time-efficient analytical techniques has resulted in many recent publications of large chronograms for a large number and wide diversity of organisms. Knowledge of the evolutionary time frame of organisms is key for research in the natural sciences. It also represent valuable information for...

Novel, Selective Calix[6]Arene - Polyethylene Glycol (C6A-PEG) Stationary Phase for Capillary Gas Chromatography (GC)

Qiuchen Huang, Zhiqiang Cai, Wei Li, Ruonan Chen, Wei Zhang, Keyun Jin, Yi Zhao, Yiwen Li & Tao Sun
A novel calix[6] arene polymer stationary phase (C6A-PEG) is reported that combines the π-electron-rich cavity of calix[6] arene (C6A) with polyethylene glycol (PEG) units for gas chromatography (GC). Thermogravimetric analysis revealed a 5% weight loss of C6A-PEG at 318 °C, and its static-coated capillary column showed high efficiency of 2924 plates/m (k = 3.48) determined by 1-octanol at 120 °C. As a result, the moderate polar C6A-PEG column showed clearly advantageous performance for the Grob...

Fecal microbiota transplantation combined with ruxolitinib as a salvage treatment for intestinal steroid-refractory acute GVHD

Yin Liu, Ye Zhao, Jiaqian Qi, Xiao Ma, Xiaofei Qi, Depei Wu & Yang Xu
Abstract Acute graft-versus-host disease (aGVHD), especially intestinal aGVHD, is one of the most severe complications after allogeneic hematopoietic stem cell transplantation (HSCT). Fecal microbiota transplantation (FMT) has been applied to the treatment of intestinal steroid-refractory aGVHD (SR-aGVHD). Ruxolitinib is the first drug recommended for SR-aGVHD. Here, we reported the outcome data from 21 patients who had received the combined treatment of FMT with ruxolitinib as a salvage treatment in intestinal SR-aGVHD after HSCT. The overall...

Additional file 1 of Understanding of bacterial lignin extracellular degradation mechanisms by Pseudomonas putida KT2440 via secretomic analysis

Zhangyang Xu, Bo Peng, Reta Birhanu Kitata, Carrie D. Nicora, Karl K. Weitz, Yunqiao Pu, Tujin Shi, John R. Cort, Arthur J. Ragauskas & Bin Yang
Additional file 1: Figure S1. The overall workflow for identifying bacterial lignin degradation pathways. Figure S2. GC–MS analysis of lignin breakdown products. Figure S3. Lignin breakdown products identified by GC–MS. Figure S4. The variation of peaks area of all lignin breakdown products. Figure S5. Main detected lignin linkages. Table S1. Occurrence of putative degradation products of lignin in different treatment conditions. Table S2. Grouped lignin breakdown products among all treatments. Table S3. Main lignin 2D...

Registration Year

  • 2022
    103

Resource Types

  • Dataset
    42
  • Text
    30
  • Collection
    26
  • Journal Article
    3
  • Image
    2

Affiliations

  • University of Tennessee at Knoxville
    103
  • Southern Medical University
    40
  • Sun Yat-sen University
    36
  • West China Hospital of Sichuan University
    32
  • Fudan University
    32
  • Nanjing Medical University
    28
  • Fudan University Shanghai Cancer Center
    24
  • Jiangsu Province Hospital
    24
  • Chinese Academy of Medical Sciences & Peking Union Medical College
    23
  • Fujian Agriculture and Forestry University
    22