127 Works

Culture wars around the world: how countries perceive divisions

Bobby Duffy, Kirstie Hewlett, George Murkin, Rebecca Benson, Rachel Hesketh, Ben Page, Gideon Skinner & Glenn Gottfried

Unequal Britain: attitudes to inequalities after Covid-19

Bobby Duffy, Rachel Elizabeth Hesketh, Hewlett Kirstie, Rebecca Benson, Alan John Wager & Jack Summers

Strong Learning of Probabilistic Tree Adjoining Grammars

Alexander Clark

A global consensus for achieving a dental cavity free future: recommendations for new caries-related policies

Nigel Berry Pitts & Catherine Mayne

Nationalpopulism, Right and Left

Daniel Rueda
For most of the postwar period the idea of merging socialist (or popular) and nationalist elements was marginal in Europe. But in the last two decades we have been witnessing a new form of social-national synthesis: nationalpopulism. This article examines this resurgence by comparing right-wing nationalpopulism and left-wing nationalpopulism. In order to do so, it focuses on four European countries: France, Italy, Greece and Spain. While there are both policy and discursive similarities between these...

Air Pollution datasets in megacities for a road increment of particulate matter

Roy Harrison & Tuan Vu
Data sets for major air pollutants (PM2.5, PM10, NO2, NOx) in London, Paris, Berlin, Beijing, Hongkong during 2014-2018.

Online Appendix: Stakeholder Engagement Strategies, National Institutions, and Firm Performance: A Configurational Perspective

Kamini Gupta, Donal Crilly & Thomas Greckhamer
Online Appendix for Stakeholder Engagement Strategies, National Institutions, and Firm Performance: A Configurational Perspective Authors: Gupta, Kamini; Crilly, Donal; Greckhamer, Thomas Request from Publisher (Wiley) to state the following for forthcoming publication in Strategic Management Journal

Roles, responsibilities, and relationships: hearing the voices of Personal Assistants and Directly Employed Care Workers

John Woolham, Caroline Norrie, Kritika Samsi & Jill Manthorpe

David Carpenter, Louise Wilkinson, David Crook, Harold Short, Paul Dryburgh, Beth Hartland, Polly Hanchett, Jonathan Mackman, Ben Wild, Simon Harris, Sean Cunningham, Jess Nelson, Adrian Jobson, Aidan Lawes, Paul Spence, Zaneta Au, Paul Caton, Arianna Ciula, Eleonora Litta Modignani Picozzi, Tamara Lopez, Paul Vetch, José Miguel Vieira, Raffaele Viglianti, John Bradley, Gerhard Brey … & Simon Tanner
The Project A fine in the reign of King of England Henry III (1216–1272) was an agreement to pay the king a sum of money for a specified concession. The rolls on which the fines were recorded provide the earliest systematic evidence of what people and institutions across society wanted from the king and he was prepared to give. They open a large window onto the politics, government, economy and society of England in the...

Trusted autonomous systems in healthcare: A policy landscape review

Rachel Elizabeth Hesketh

New Bearings in Post-Conflict Evaluation: A Principle-Based Approach

Rachel Kerr, Tiffany Fairey, Jelena Petrovic & Andrew James William Gow

Implications of the post-Brexit immigration system for temporary migration routes

Rachel Elizabeth Hesketh, Jack Summers & Mark Kleinman

The Introduction and Development of the Nursing Associate Role: Policymaker and Practitioner Perspectives

Ian Kessler, Jess Harris, Jill Manthorpe, Jo Moriarty & Nicole Steils

Plumbing poverty in U.S. cities: A report on gaps and trends in household water access, 2000 to 2017

Katie Meehan, Jason R. Jurjevich, Alison Griswold, Nicholas M.J.W. Chun & Justin Sherrill

Creative work: possible futures after Covid-19

Lauren England, Federica Viganò, Roberta Comunian & Jessica Tanghetti

Data from: Decreased brain connectivity in smoking contrasts with increased connectivity in drinking

Wei Cheng, Edmund T. Rolls, Trevor W. Robbins, Weikang Gong, Zhaowen Liu, Wujun Lv, Jingnan Du, Hongkai Wen, Liang Ma, Erin Burke Quinlan, Hugh Garavan, Eric Artiges, Dimitri Papadopoulos Orfanos, Michael N. Smolka, Gunter Schumann, Keith Kendrick & Jianfeng Feng
In a group of 831 participants from the general population in the Human Connectome Project, smokers exhibited low overall functional connectivity, and more specifically of the lateral orbitofrontal cortex which is associated with non-reward mechanisms, the adjacent inferior frontal gyrus, and the precuneus. Participants who drank a high amount had overall increases in resting state functional connectivity, and specific increases in reward-related systems including the medial orbitofrontal cortex and the cingulate cortex. Increased impulsivity was...

Data from: A case-by-case analysis of four imprinted retrogenes

Ruth B McCole, Noeleen B Loughran, Mandeep Chahal, Luis P Fernandes, Roland G Roberts, Franca Fraternali, Mary J O'Connell & Rebecca J Oakey
Retroposition is a widespread phenomenon resulting in the generation of new genes that are initially related to a parent gene via very high coding sequence similarity. We examine the evolutionary fate of four retrogenes generated by such an event; mouse Inpp5f_v2, Mcts2, Nap1l5, and U2af1-rs1. These genes are all subject to the epigenetic phenomenon of parental imprinting. We first provide new data on the age of these retrogene insertions. Using codon-based models of sequence evolution,...

Data from: Short-term and medium-term survival of critically ill patients with solid tumours admitted to the intensive care unit: a retrospective analysis

Richard Fisher, Carole Dangoisse, Siobhan Crichton, Craig Whiteley, Luigi Camporota, Richard Beale & Marlies Ostermann
Objectives: Patients with cancer frequently require unplanned admission to the Intensive Care Unit (ICU). Our objectives were to assess hospital and 180-day mortality in patients with a non-haematological malignancy and unplanned ICU admission, and to identify which factors present on admission were the best predictors of mortality. Design: Retrospective review of all patients with a diagnosis of solid tumours following unplanned admission to the ICU between 1st August 2008 and 31st July 2012. Setting: Single...

Data from: In vivo dynamics of skeletal muscle Dystrophin in zebrafish embryos revealed by improved FRAP analysis

Fernanda Bajanca, Vinicio Gonzalez-Perez, Sean J. Gillespie, Cyriaque Beley, Luis Garcia, Eric Theveneau, Richard P. Sear & Simon M. Hughes
Dystrophin forms an essential link between sarcolemma and cytoskeleton, perturbation of which causes muscular dystrophy. We analysed Dystrophin binding dynamics in vivo for the first time. Within maturing fibres of host zebrafish embryos, our analysis reveals a pool of diffusible Dystrophin and complexes bound at the fibre membrane. Combining modelling, an improved FRAP methodology and direct semi-quantitative analysis of bleaching suggests the existence of two membrane-bound Dystrophin populations with widely differing bound lifetimes: a stable,...

Data from: Ecosystem services provided by bromeliad plants: a systematic review

Geraldine Ladino, Fabiola Ospina-Bautista, Jaime Estévez Varón, Lucie Jerabkova & Pavel Kratina
The unprecedented loss of biological diversity has negative impacts on ecosystems and the associated benefits which they provide to humans. Bromeliads have high diversity throughout the Neotropics, but they have been negatively affected by habitat loss and fragmentation, climate change, herbivorous species invasions, and they are also being commercialized for ornamental use. These plants provide direct benefits to the human society and they also form micro ecosystems in which accumulated water and nutrients support the...

Data from: Brain myo-inositol as a potential marker of amyloid-related pathology: a longitudinal study.

Olga Voevodskaya, Konstantinos Poulakis, Pia Sundgren, Danielle Van Westen, Sebastian Palmqvist, Lars Olof Wahlund, Erik Stomrud, Oskar Hansson & Eric Westman
Objective: To investigate the association between longitudinal changes in proton magnetic spectroscopy (MRS) metabolites and amyloid pathology in non-demented individuals; to explore the relationship between MRS and cognitive decline. Methods: In this longitudinal multiple time point study (a subset of the Swedish BioFINDER) we included cognitively healthy participants, individuals with subjective cognitive decline and mild cognitive impairment (MCI). MRS was acquired serially in 294 participants (670 individual spectra) from the posterior cingulate/precuneus. Using mixed-effects models,...

One-year sustained efficacy of erenumab in episodic migraine: Results of the STRIVE study - supplementary data

Peter Goadsby
Objective: To assess efficacy and tolerability of 1-year erenumab treatment in patients with episodic migraine. Methods: Patients were randomized (n=955; 1:1:1) during the 24-week double-blind treatment phase (DBTP) to monthly subcutaneous placebo, erenumab 70 or 140mg. At Week 24, 845 patients were re-randomized (1:1) to erenumab 70 or 140mg during the 28-week dose-blinded active-treatment phase (ATP). Monthly migraine days (MMD), achieving ≥50%, ≥75% and 100% reduction in MMD, and safety/tolerability were assessed. Results: Mean MMD...

In-depth comparative toxicogenomics of glyphosate and Roundup herbicides: Histopathology, transcriptome and epigenome signatures, and DNA damage

Robin Mesnage, Mariam Ibragim, Daniele Mandrioli, Laura Falcioni, Eva Tibaldi, Inger Brandsma, Fiorella Belpoggi, Emma Bourne, Emanuel Savage, Charles A Mein & Michael Antoniou
Whether or not glyphosate activates cellular mechanisms involved in carcinogenesis remains controversial. We tested whether glyphosate and three glyphosate-based commercial herbicide formulations activate mechanisms known to be key characteristics of carcinogens. The mammalian stem cell-based genotoxicity ToxTracker assay showed that the representative EU formulation Roundup MON 52276 and the UK formulation Roundup MON 76473, but not glyphosate and the US Roundup formulation MON 76207, activated oxidative stress and unfolded protein responses. High-throughput molecular profiling of...

Mapping of specialist primary health care services in England for people who are homeless (full report)

Maureen Crane, Gaia Cetrano, Louise Joly, Sarah Coward, Blanaid Daly, Chris Ford, Heather Gage, Jill Manthorpe & Peter Williams

Connected tech: smart or sinister? A call for evidence from Department for Digital, Culture, Media & Sport

Justyna Lisinska, Paul Coulton, Richard Hyde, Joseph Lindley, Luke Moffat, Mohammad Reza Mousavi, Sarvapali D. Ramchurn, Paurav Shukla, Michael Stead, Beverley Townsend & Jennifer Williams

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