504 Works

Substrate utilisation profiles for saprotrophic fungi and moisture content data from soil sampled in an upland grassland experiment at Sourhope, Scotland, 2001 [NERC Soil Biodiversity Programme]

L.J. Deacon, E.J. Pryce-Miller, J.C. Frankland, B.W. Bainbridge, P.D. Moore, C.H. Robinson & N. Parekh
This set of data comprises substrate utilisation profiles for saprotrophic fungi (using the commercially available BIOLOG plate method) and moisture content data from soils sampled from experimental plots at Sourhope, Scotland. The data were collected in order to determine how the high species richness of decomposer (saprotrophic) fungi and their relative frequencies of occurrence influence the decomposition of organic matter. Data were collected during a project funded under the NERC Soil Biodiversity Programme, established in...

Data from: Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi C. Lam, Felix D. Weiss, Zoe Powis, Pim Suwannarat, Christopher J. Lelliot, Sally J. Dawson, Jacqueline K. White & Karen P. Steel
Adult-onset hearing loss is very common but we know little about the underlying molecular pathogenesis, impeding development of therapies. We took a genetic approach to identify new molecules involved in hearing loss by screening a large cohort of newly-generated mouse mutants using a sensitive electrophysiological test, the auditory brainstem response. We review here the findings from this screen. Thirty-eight unexpected genes associated with raised thresholds were detected from our unbiased sample of 1,211 genes tested,...

The impact of the coronavirus (Covid-19) on people who work as social care Personal Assistants

John Woolham, Kritika Samsi, Caroline Norrie & Jill Manthorpe

Intracellular sodium elevation reprograms cardiac metabolism: Metabolomics data

Dunja Aksentijevic, Anja Karlstaedt, Marina Basalay, Brett O'Brien, David Sanchez-Tatay, Seda Eminaga, Alpesh Thakker, Daniel Tennant, William Fuller, Thomas Eykyn, Heinrich Taegtmeyer & Michael Shattock
Intracellular Na elevation in the heart is a hallmark of pathologies where both acute and chronic metabolic remodeling occurs. We assessed whether acute (75μM ouabain 100nM blebbistatin) and chronic myocardial Naiload (PLM3SA mouse) are causally linked to metabolic remodeling and whether the hypertrophied failing heart shares a common Na-mediated metabolic ‘fingerprint’. Control (PLMWT), transgenic (PLM3SA), ouabain treated and hypertrophied Langendorff-perfused mouse hearts were studied by 23Na, 31P, 13C NMR followed by 1H NMR metabolomic profiling....

Traits data of exotic species in four tropical botanic gardens and adjacent natural forests

Decky Junaedi, Gurutzeta Guillera-Arroita, Peter Vesk, Michael McCarthy, Mark Burgman & Jane Catford
The establishment of new botanic gardens in tropical regions highlights a need for weed risk assessment tools suitable for tropical ecosystems. The relevance of plant traits for invasion into tropical rainforests has not been well studied. Working in and around four botanic gardens in Indonesia where 600 exotic species have been planted, we estimated the effect of four plant traits and time since species were introduced on: a) naturalization probability of exotic species; b) the...

Traits data of naturalized and non-naturalized alien species of four Indonesian Botanic Gardens

Decky Junaedi, Jane Catford, Mark Burgman, Michael McCarthy, Gurutzeta Guillera-Arroita & Peter Vesk
The establishment of new botanic gardens in tropical regions highlights a need for weed risk assessment tools suitable for tropical ecosystems. The relevance of plant traits for invasion into tropical rainforests has not been well studied. Working in and around four botanic gardens in Indonesia where 590 alien species have been planted, we estimated the effect of four plant traits, plus time since species introduction, on: a) the naturalization probability and b) abundance (density) of...

Unpopular Justice: Law and the Inexpediency of Culture in North India

Kriti Kapila

The “fault lines” in the UK’s culture wars

Bobby Duffy, Kirstie Hewlett, George Murkin, Rebecca Benson, Rachel Hesketh, Ben Page, Gideon Skinner & Glenn Gottfried

Relationships between plant-soil feedbacks and functional traits

Nianxun Xi, Peter Adler, Dongxia Chen, Hangyu Wu, Jane Catford, Peter Van Bodegom, Michael Bahn, Kerri Crawford & Chengjin Chu
Plant-soil feedbacks (PSF) and functional traits are two active but not well theoretically integrated areas of research. However, PSF and traits are both affected by life history evolution, so the two should theoretically be related. We provide a conceptual framework to link plant functional traits to two types of PSF metrics, and hypothesize that individual PSF (plant performance in conspecific versus heterospecific soil) should be related to the fast-slow trait spectrum, while pairwise PSF (the...

The Future of Film Report 2021

Alex Stolz, Sarah Atkinson & Helen Kennedy

Experimental study on the seismic behavior of RC columns improved with central large-diameter butted steel rods

Hanming Zhang, Jie Luo, Jianchun Xiao, Jing Chen, Zhuoqun Liu, Yi Zhang, Zongli Luo & Hong Zhang
Abstract A reinforced concrete (RC) column improved with central large-diameter butted steel rods (CLBSR column) has been proposed to increase the limit value of the axial compression ratio. This paper presents the seismic behavior analysis of CLBSR columns subjected to low-cycle reciprocating loading. The CLBSR columns were also compared with the RC column improved with central large-diameter steel rods (CLSR column) and the RC column improved with central reinforcement bars (CRB column) under the same...

Experimental study on the seismic behavior of RC columns improved with central large-diameter butted steel rods

Hanming Zhang, Jie Luo, Jianchun Xiao, Jing Chen, Zhuoqun Liu, Yi Zhang, Zongli Luo & Hong Zhang
Abstract A reinforced concrete (RC) column improved with central large-diameter butted steel rods (CLBSR column) has been proposed to increase the limit value of the axial compression ratio. This paper presents the seismic behavior analysis of CLBSR columns subjected to low-cycle reciprocating loading. The CLBSR columns were also compared with the RC column improved with central large-diameter steel rods (CLSR column) and the RC column improved with central reinforcement bars (CRB column) under the same...

Patient perspectives of recovery after hip fracture: a systematic review and qualitative synthesis

Natasha Beer, Aleena Riffat, Brittannia Volkmer, David Wyatt, Kate Lambe & Katie J. Sheehan
The purpose of the current review is to synthesize the evidence of patients’ perspectives of recovery after hip fracture across the care continuum. A systematic search was conducted, focusing on qualitative data from hip fracture patients. Screening, quality appraisal, and a subset of articles for extraction were completed in duplicate. Themes were generated using a thematic synthesis of data from original studies. Fourteen high-quality qualitative studies were included. Four review themes were identified: recovery as...

Local CpG density affects the trajectory and variance of age-associated DNA methylation changes

Jonathan Higham, Lyndsay Kerr, Qian Zhang, Rosie M. Walker, Sarah E. Harris, David M. Howard, Emma L. Hawkins, Anca-Larisa Sandu, J. Douglas Steele, Gordon D. Waiter, Alison D. Murray, Kathryn L. Evans, Andrew M. McIntosh, Peter M. Visscher, Ian J. Deary, Simon R. Cox & Duncan Sproul
Abstract Background DNA methylation is an epigenetic mark associated with the repression of gene promoters. Its pattern in the genome is disrupted with age and these changes can be used to statistically predict age with epigenetic clocks. Altered rates of aging inferred from these clocks are observed in human disease. However, the molecular mechanisms underpinning age-associated DNA methylation changes remain unknown. Local DNA sequence can program steady-state DNA methylation levels, but how it influences age-associated...

Targeted delivery and ROS-responsive release of Resolvin D1 by platelet chimeric liposome ameliorates myocardial ischemia–reperfusion injury

Xueyi Weng, Haipeng Tan, Zheyong Huang, Jing Chen, Ning Zhang, Qiaozi Wang, Qiyu Li, Jinfeng Gao, Dili Sun, Wusiman Yakufu, Zhengmin Wang, Weiyan Li, Guangrui Zhu, Zhiqing Pang, Yanan Song, Juying Qian & Junbo Ge
Abstract Resolvin D1 (RvD1) has been shown to provide effective protection against ischemia–reperfusion injury in multiple vital organs such as the heart, brain, kidney. However, the clinical translational potential of systemic administration of RvD1 in the treatment of ischemia–reperfusion injury is greatly limited due to biological instability and lack of targeting ability. Combining the natural inflammatory response and reactive oxygen species (ROS) overproduction after reperfusion injury, we developed a platelet-bionic, ROS-responsive RvD1 delivery platform. The...

Inequalities around the globe: what the world sees as most serious

Bobby Duffy, George Murkin, Kirstie Hewlett, Rebecca Benson & Rachel Elizabeth Hesketh

Carcharhinus amblyrhynchos and Carcharhinus albimarginatus underwater acoustic telemetry data - Chagos Archipelago 2014-2018

Michael Williamson
A wide array of technologies are available for gaining insight into the movement of wild aquatic animals. Although acoustic telemetry may lack the fine-scale resolution of some satellite tracking technologies, the substantially longer battery life can yield important long-term data on behaviour and movement for low per-unit cost. Typically, however, receiver arrays are designed to maximise spatial coverage at the cost of positional accuracy leading to potentially longer detection gaps as individuals move out of...

Rapid review on the ethical international recruitment of healthcare workers

Jo Moriarty, Jill Manthorpe, Stephen Martineau, Caroline Norrie & Kritika Samsi

The Development of the Nursing Associate Role: The Postholder Perspective

Ian Kessler, Nicole Steils, Jess Harris, Jill Manthorpe & Jo Moriarty

Clinical features in X-linked myotubular myopathy carriers

Stacha Reumers, Frederik Braun, Jennifer Spillane, Johann Böhm, Maartje Pennings, Meyke Schouten, Anneke Van Der Kooi, Reghan Foley, Carsten Bönnemann, Erik-Jan Kamsteeg, Corrie Erasmus, Ulrike Schara-Schmidt, Heinz Jungbluth & Nicol Voermans
Objective: To characterize the spectrum of clinical features in a cohort of X-linked myotubular myopathy (XL-MTM) carriers, including prevalence, genetic features, clinical symptoms and signs, as well as associated disease burden. Methods: We performed a cross-sectional online questionnaire study among XL-MTM carriers. Participants were recruited from patient associations, medical centers and registries in the United Kingdom, Germany and the Netherlands. We used a custom-made questionnaire, the Checklist Individual Strength (CIS), the Frenchay Activities Index (FAI),...

Fragmentation in trader preferences among multiple markets: Market coexistence versus single market dominance

Aleksandra Alorić, Robin Nicole & Peter Sollich
Technological advancement has lead to an increase in number and type of trading venues and diversification of goods traded. These changes have re-emphasized the importance of understanding the effects of market competition: does proliferation of trading venues and increased competition lead to dominance of a single market or coexistence of multiple markets? In this paper, we address these questions in a stylized model of Zero Intelligence traders who make repeated decisions at which of three...

Dundee Cultural Recovery: a policy report

Lauren England

What do we know about hoarding behaviour and treatment approaches for older people? A thematic review

Nicole Steils, John Woolham, Jill Manthorpe, Stephen Martineau, Jennifer Owen, Martin Stevens & Michela Tinelli

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