Leaf functional traits are key indicators of plant functions useful for inferring complex plant processes, including their responses to environmental changes. Vegetation indices (VIs) composed of a few reflectance wavelengths hold the advantages of being relatively simple and effective and have been widely used within remote sensing to estimate leaf traits. However, the difference between the reflectance from the upper and lower part of the leaf suggests that leaf reflectance mainly provides one-sided information, constraining...

Sample preparation and Intensity dependence of collagen

Additional file 4: Supplementary Table 3. The abbreviations of cancer types, alternative polyadenylation regulators and immune-related checkpoints in this study.

Additional file 5: Supplementary Table 4. The patients’ clinical information (n = 16) in this study.

Additional file 1: Table S1 The overlapped targets between NC and lung cancer. Fig. S1 A–C GSDMC, GSDMD and GSDME protein expression were analyzed by Western blotting. D WB analyses of GSDMC, GSDMD and GSDME in lung cancer cell lines and BEAS-2B cell line. Protein levels are expressed as mean ± SD (n=3). Fig. S2 H1688 or A549 cells were transfected with siRNA targeting caspase 3 (siRNA-cas3-1/2/3) or control siRNA for 24 h. Fig. S3...

Additional file 5: Supplementary Table 4. The patients’ clinical information (n = 16) in this study.

Multimode fibers (MMFs) are emerging as promising transmission media for delivering images. However, strong mode coupling inherent in MMFs induces difficulties in directly projecting two-dimensional images through MMFs. By training two subnetworks named Actor-net and Model-net synergetically, Ref. [1] alleviated this issue and demonstrated projecting images through MMFs with high fidelity. In this work, we make a step further by improving the generalization ability to greyscale images. The modified projector network contains three subnetworks, namely...

Additional info on data processing

Diabetic retinopathy (DR) represents an important microvascular complication of diabetes, which is the top etiology of vision impairment worldwide. Although interleukin (IL)-17A is increasingly implicated in DR development, the underlying cellular mechanisms remain poorly defined. This work aims to evaluate IL-17A levels in the retina of streptozotocin (STZ)-induced diabetic mice and elucidate their potential roles. We found IL-17A was upregulated in diabetic retina after intraperitoneal injection of STZ and high-glucose (HG)-cultured primary Müller cells. IL-17A...

Diabetic retinopathy (DR) represents an important microvascular complication of diabetes, which is the top etiology of vision impairment worldwide. Although interleukin (IL)-17A is increasingly implicated in DR development, the underlying cellular mechanisms remain poorly defined. This work aims to evaluate IL-17A levels in the retina of streptozotocin (STZ)-induced diabetic mice and elucidate their potential roles. We found IL-17A was upregulated in diabetic retina after intraperitoneal injection of STZ and high-glucose (HG)-cultured primary Müller cells. IL-17A...

Excessive proliferation and migration of vascular smooth muscle cells (VSMCs) play a fundamental role in the pathogenesis of hypertension-related vascular remodeling. β-aminoisobutyric acid (BAIBA) is a nonprotein β-amino acid with multiple pharmacological actions. Recently, BAIBA has been shown to attenuate salt‑sensitive hypertension, but the role of BAIBA in hypertension-related vascular remodeling has yet to be fully clarified. This study examined the potential roles and underlying mechanisms of BAIBA in VSMC proliferation and migration induced by...

This systematic review aimed to identify the referral criteria for palliative care in patients with Parkinson’s disease. We conducted an electronic search for publications on referral criteria for palliative care in patients with Parkinson’s disease in six electronic databases. The articles were thoroughly reviewed by two independent reviewers for inclusion using a predefined data extraction list. The referral criteria were thematically classified using a coding methodology. This systematic review included 36 publications. We identified 14...

The accurate detection of nanoplastics is crucial due to their harmful effects on the environment and human beings. In this research, we successfully constructed an Ag/CuO nanowire (NW)/BaTiO3@PVDF Bowl-shaped substrate with a nanowire-in-Bowl-shaped piezoelectric cavity structure that can modulate surface-enhanced Raman scattering (SERS) by the piezoelectric effect by the virtue of the molecular gripper of the CuO NW and optical field amplifier of the Bowl-shaped cavity. Due to its unique nanowire-in-Bowl-shaped structure and piezoelectrically modifiable...

Supplementary Material

Learning-based computer-generated holography (CGH) algorithms appear as novel alternatives to generate phase-only holograms. However, most existing learning-based approaches underperform their iterative peers in terms of display quality. Here, we propose an unsupervised Fourier-inspired neural network that could generate phase-only holograms in real time and obtain high-fidelity reconstructed images. Both simulation and experiment were performed to showcase its capability. By explicitly leveraging Fourier transforms within the neural network architecture, global features of the holograms are more...

Purpose: Muscle groups within the tongue in healthy and diseased populations show different behaviors during speech. Visualizing and quantifying strain patterns of these muscle groups during tongue motion can provide insights into tongue motor control and adaptive behaviors of a patient. Method: We present a pipeline to estimate the strain along the muscle fiber directions in the deforming tongue during speech production. A deep convolutional network estimates the crossing muscle fiber directions in the tongue...

Mesothelin (MSLN) is an attractive therapeutic target for antibody drug conjugates (ADC) because of significant differences in expression pattern between diseased and normal tissues. RC88-ADC is a novel ADC, targeting MSLN, and inhibits tumor growth significantly in mice xenograft models. We performed an 11-week repeated dose toxicity study of RC88-ADC via intravenous injection in Cynomolgus Monkeys with an 8-Week recovery period according to International Conference on Harmonization (ICH) S9 and S6(R1). RC88-ADC was administered to...

Mesothelin (MSLN) is an attractive therapeutic target for antibody drug conjugates (ADC) because of significant differences in expression pattern between diseased and normal tissues. RC88-ADC is a novel ADC, targeting MSLN, and inhibits tumor growth significantly in mice xenograft models. We performed an 11-week repeated dose toxicity study of RC88-ADC via intravenous injection in Cynomolgus Monkeys with an 8-Week recovery period according to International Conference on Harmonization (ICH) S9 and S6(R1). RC88-ADC was administered to...

Some equations about the construction of the diffuser sheet model

Psoriasis is a chronic inflammatory skin disease. Mast cells are significantly increased and activated in psoriatic lesions and are involved in psoriatic inflammation. Some endogenous substances can interact with the surface receptors of mast cells and initiate the release of downstream cytokines that participate in inflammatory reactions. Neuroblast differentiation-associated protein (AHNAK) is mainly expressed in the skin, esophagus, kidney, and other organs and participates in various biological processes in the human body. AHNAK and its...

We construct a modified measure of disaggregation quality (MDQ) based on the disaggregation quality (DQ) measure from Chen et al. Both are parsimonious measures of disclosure quality in the annual report using the percentage of nonmissing financial statement items in Compustat. However, we take additional screening steps to minimize counting errors by resolving missing values due to GAAP changes over time and using a more comprehensive set of accounting equations from Casey et al. We...

Supplemental material, sj-docx-1-jaf-10.1177_0148558X221148626 for Measuring Disaggregation Quality by Ryan Casey, Feng Gao, Michael Kirschenheiter, Siyi Li and Shailendra Pandit in Journal of Accounting, Auditing & Finance

Bandwagon cues are system-aggregated information about crowd behavior or peer endorsement displayed on a web interface (e.g., the number of likes on a Facebook post). Despite the recent proliferation of research on the effect of bandwagon cues on credibility perceptions, a comprehensive meta-analytic review of this effect has not yet been performed and published. Based on 161 effect sizes from 41 studies, the current meta-analysis revealed that bandwagon cues had a positive, albeit small, effect...

Supplemental material, sj-docx-1-crx-10.1177_00936502221124395 for Do Bandwagon Cues Affect Credibility Perceptions? A Meta-Analysis of the Experimental Evidence by Sai Wang, Tsz Hang Chu and Guanxiong Huang in Communication Research

BackgroundThe anatomical positioning of the graft during anterior cruciate ligament reconstruction (ACLR) is of great significance for restoring normal knee kinematics and preventing early joint degeneration. Therefore, the adjustment of the mispositioned guide pin becomes extremely important. Our research aims to test the time-zero biomechanical properties in adjusting inaccurate guide pins to the center of the tibial footprint in anatomical anterior cruciate ligament single-bundle reconstruction.MethodsPorcine tibias and bovine extensor tendons were used to simulate a...