3 Works

Plasmodium infection induces cross-reactive antibodies to carbohydrate epitopes on the SARS-CoV-2 Spike protein

Sarah Lapidus, Feimei Liu, Arnau Casanovas-Massana, Yile Dai, John D. Huck, Carolina Lucas, Jon Klein, Renata B. Filler, Madison S. Strine, Mouhamad Sy, Awa B. Deme, Aida S. Badiane, Baba Dieye, Ibrahima Mbaye Ndiaye, Younous Diedhiou, Amadou Moctar Mbaye, Cheikh Tidiane Diagne, Inés Vigan-Womas, Alassane Mbengue, Bacary D. Sadio, Moussa M. Diagne, Adam J. Moore, Khadidiatou Mangou, Fatoumata Diallo, Seynabou D. Sene … & Amy K. Bei
Individuals with acute malaria infection generated high levels of antibodies that cross-react with the SARS-CoV-2 Spike protein. Cross-reactive antibodies specifically recognized the sialic acid moiety on N-linked glycans of the Spike protein and do not neutralize in vitro SARS-CoV-2. Sero-surveillance is critical for monitoring and projecting disease burden and risk during the pandemic; however, routine use of Spike protein-based assays may overestimate SARS-CoV-2 exposure and population-level immunity in malaria-endemic countries.

Etude histologique du foie, de l'intestin et de la rate de souris infestées à Schistosoma Mansoni puis soumises à un traitement suppressif à l'extrait aqueux de sida pilosa retz

Ulrich Membe Femoe, Catherine Cannet, Hermine Boukeng Jatsa, Joseph Bertin Kadji Fassi, Paul Desire Djomeni Dzeufiet, Theophile Dimo, Tchuem Tchuente, Louis-Albert & Pierre Kamtchouing
La schistosomiase demeure un réel problème de santé publique dans les pays tropicaux. La pathologie à Schistosoma mansoni est principalement causée par les Tmufs qui, embolisés dans le foie et l’intestin, sont à l’origine d’une nécrose tissulaire, de la mise en place d’une réaction inflammatoire granulomateuse pouvant évoluer vers une fibrose et d’un dysfonctionnement tissulaire. L’utilisation intensive du praziquantel, unique médicament contre toutes les formes de schistosomiase, est parfois à l’origine d’échecs thérapeutiques et pourrait...

Local adaptation in thermal tolerance for a tropical butterfly across ecotone and rainforest habitats

Michel AK Dongmo, Rachid Hanna, Thomas B Smith, KKM Fiaboe, Abraham Fomena & Timothy C Bonebrake
Thermal adaptation to habitat variability can determine species vulnerability to environmental change. For example, physiological tolerance to naturally low thermal variation in tropical forests species may alter their vulnerability to climate change impacts, compared with open habitat species. However, the extent to which habitat-specific differences in tolerance derive from within-generation versus across-generation ecological or evolutionary processes are not well characterized. Here we studied thermal tolerance limits of a Central African butterfly (Bicyclus dorothea) across two...

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Affiliations

  • Université de Yaoundé I
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  • Northwestern University
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  • Serimmune (United States)
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  • Noguchi Memorial Institute for Medical Research
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  • Stanford University
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  • International Institute of Tropical Agriculture
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  • Institut Pasteur de Dakar
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  • University of Antioquia
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  • Yale University
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  • University of California Los Angeles
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