In collaboration with the Public Health Agency of Canada (PHAC), this table provides Canadians and researchers with preliminary data to monitor only the confirmed cases of coronavirus (COVID-19) in Canada. Given the rapidly-evolving nature of this situation, these data are considered preliminary.

Additional file 2 Supplementary Figure S1. The expression levels of LTRs in the Cluster L4 of Figure 3A. Supplementary Figure S2. The primers used to validate the expressions of 13 MacERV3 LTRs. (A) The alignment of the forward primer MacERV3_LTR2_34_F and the 13 MacERV3 LTRs. (B) The alignment of the reverse primer MacERV3_LTR2_34_R and the 13 MacERV3 LTRs. (C) The precise loci of the two primers in one of the selected MacERV3 LTRs, MacERV3_LTR2_34. Supplementary...

Abstract Background Mucosal-associated invariant T (MAIT) cells are innate-like T cells, some studies have reported that the number of circulating MAIT cells reduced in patients with acute graft-versus-host-disease (aGVHD) development. However, the role of donor MAIT cells on aGVHD development and subsequent functional change still remain unclear. Methods The study recruited 86 patients with hematological malignancies who underwent allogeneic hematopoietic cell transplantation (HCT) from May 1, 2018 to June 30, 2019. MAIT cells, their subset,...

Additional file 2: Supplementary figure S2. The pairwise patristic distance between P.1 sequences in clusters identified by each clustering method.

Additional file 1: Supplementary figure S1. The median and interquartile pairwise SNP distance between sequences collected in the study period by week of 2021.

Additional file 6. Draft data extraction items.

A new clerodane diterpenoid, crotolanin A (1), along with three known clerodane diterpenoids, crotoeurin B (2), teucvidin (3) and teucvin (4), was isolated from the ethanol extract of the leaves and twigs of Croton lachnocarpus Benth. Their structures were identified by extensive NMR spectroscopic and HRESIMS analyses. The dopaminergic neuroprotective activity of compounds 1-4 was tested by using transgenic Caenorhabditis elegans pathological model. Compound 2 alleviated dopaminergic neuron degeneration of worms induced by 6-hydroxydopamine (6-OHDA)...

Additional file 2. Search strategies.

Additional file 2. Search strategies.

Additional file 3. List of grey literature relevant websites.

Abstract Purpose To inform recommendations by the Canadian Task Force on Preventive Health Care on potentially inappropriate prescribing and over-the-counter (OTC) medication use among adults aged 65 years and older in primary care settings. This protocol outlines the planned scope and methods for a systematic review of the benefits and harms and acceptability of interventions to reduce potentially inappropriate prescriptions and OTC medication use. Methods De novo systematic reviews will be conducted to synthesize the...

Additional file 1: The supporting materials of implementation of contact tracing in China, the estimated parameters in Fujian case, the initial values of state variables and parameters used in Jilin case and the sensitivity analysis on the number of daily cases and isolated individuals.

Additional file 4: Table S1. Substances and their concentrations in SMI (Lot No. 1907018).

Additional file 5: Table S2. DEGs in Model, S+Rg, S, and Rg groups.

Additional file 6: Table S3. Co-regulated DEGs among the three-treatment group and Model group.

Additional file 10: Supplementary Figure S10. Spearman correlation coefficient between 22 immune cells was calculated for CESC (A), OV (B), UCEC (C), and UCS D. Red bubbles indicate positive correlations and blue bubbles indicate negative correlations. The numbers in the bubbles represent the correlation coefficients.

Additional file12: Supplementary Figure S12. Spearman correlation between NRGs expression level and IC50 level of drugs. A Bubble chart for CESC. B Bubble chart for OV. C Bubble chart for UCEC. D Bubble chart for UCS. The bubble color indicates the degree of correlation index. The bubble size indicates the P-value. The correlation with P<0.05 & |Cor|>0.3 were retained to produce the figure.

Additional file 15: Supplementary Table 3. The results of Univariate Cox regression analysis for pan-cancer.

Additional file 1: Table S1. Univariate Cox regression analyses for the incidence of CVD, CHD and stroke.

Objectives: A rapid review is a form of evidence synthesis considered a resource-efficient alternative to the conventional systematic review. Despite a dramatic rise in the number of rapid reviews commissioned and conducted in response to the coronavirus disease 2019 pandemic, published evidence on the optimal methods of planning, doing, and sharing the results of these reviews is lacking. The Priority III study aimed to identify the top 10 unanswered questions on rapid review methodology to...

Objectives: A rapid review is a form of evidence synthesis considered a resource-efficient alternative to the conventional systematic review. Despite a dramatic rise in the number of rapid reviews commissioned and conducted in response to the coronavirus disease 2019 pandemic, published evidence on the optimal methods of planning, doing, and sharing the results of these reviews is lacking. The Priority III study aimed to identify the top 10 unanswered questions on rapid review methodology to...

Derivation of the formula for the main text

Research Data for Superselective arterial microcoil embolization for delayed bleeding after peroral endoscopic myotomy by Xuechen Liu, Yonghong Zhou, Xiaoyu Jiang, Li Liu, Dongqiang Zhao, Huihui Ma, Hui Tian and Huiqing Jiang in Journal of International Medical Research

Additional file 7: Mann-Whitney p-values corresponding to relative frequency differences between RML and mock infected mice for each cell sub-cluster in the subset neuron dataset.

Additional file 8: Differentially expressed transcripts between cells isolated from RML and Mock infected mice within each cell cluster in the full single cell RNAseq atlas. Differentially expressed transcripts were defined by criteria of FDR p-value < 0.05, |log2FC| > 0.5 and �ll-expression difference > -0.1 or < 0.1 for increased/decreased genes respectively.