Background: The Rhynchosporium species complex consists of hemibiotrophic fungal pathogens specialized to different sweet grass species including the cereal crops barley and rye. A sexual stage has not been described, but several lines of evidence suggest the occurrence of sexual reproduction. Therefore, a comparative genomics approach was carried out to disclose the evolutionary relationship of the species and to identify genes demonstrating the potential for a sexual cycle. Furthermore, due to the evolutionary very young...

Objectives: The lack of cognitive assessment tools suitable for people with minimal formal education is a barrier to identify cognitive impairment in Vietnam. Our aims were to (i) evaluate the feasibility of conducting the Montreal Cognitive Assessment-Basic (MoCA-B) and Informant Questionnaire On Cognitive Decline in the Elderly (IQCODE) remotely on the Vietnamese older adults, (ii) examine the association between the two tests, (iii) identify demographic factors correlated with these tools. Methods: The MoCA-B was adapted...

Background Virtual Reality (VR) is an immersive computer-generated environment that provides a multi-sensory experience for the user. Modern technology allows the user to explore and interact with the virtual environment, offering opportunities for rehabilitation. The use of immersive VR in the management of musculoskeletal shoulder pain is relatively new and research is equired to demonstrate its feasibility and effectiveness in this field. Aim The aims of this study were, firstly, to explore physiotherapists’ beliefs and...

Background:Approximately 50% of intensive care survivors experience persistent psychological symptoms. Eye-movement desensitisation and reprocessing (EMDR) is a widely recommended trauma-focussed psychological therapy, which has not been investigated systematically in a cohort of intensive care survivors: We therefore conducted a randomised pilot feasibility study of EMDR, using the Recent Traumatic Episode Protocol (R-TEP), to prevent psychological distress in intensive care survivors. Findings will determine whether it would be possible to conduct a fully-powered clinical effectiveness trial...

In 2019 the final on-farm validation of the UH prediction system (funded by Ceres, in collaboration with Agri-tech Services) took place on eight participating sites (from six farms) in England and Scotland. The aim of the project was to conduct an on-farm validation of the prediction system, in order to provide a simple, user friendly decision support system to growers to control the disease with fewer fungicide applications. A wide range of criteria were covered...

Background: The alarming growth of stimulant-involved deaths underscores the urgent need for states to expand existing opioid-specific approaches to intentionally reach and serve people who use stimulants. Recent permission from federal agencies has allowed states to spend grant funding that was previously restricted to opioid-related activities on approaches addressing stimulant use. Objectives: This manuscript describes the rationale, methods, and initial results supporting the implementation of Missouri’s recent stimulant-focused efforts – including previously-prohibited activities such as...

The presentations at the Conference address the diversity of scales, processes and interactions affecting air pollution and its impact on health and the environment. As usual, the conference is stimulating cross-fertilisation of ideas and cooperation between the different air pollution science and user communities. There is greater involvement of city, regional and global air pollution, climate change, users and health communities at the meeting. The focus of the international conference will be to discuss the...

This presentation was given using Microsoft Powerpoint and Microsoft Teams at the Doctoral Training Alliance (DTA) Energy Summer School 2020 on 9th September 2020. There is a video/audio recording of the session available to download, as well as a PDF of the Powerpoint slides. The presentation gives an overview of the concept of open access, why it is important, how it can benefit researchers and how researchers can maximise the opportunities provided by open access...

Background:4-Fluoroethylphenidate (4F-EPH) is a psychoactive substance, sold primarily over the Internet as a `research chemical'. Recreational and `functional' use of this drug has been reported by online user fora. Scientifically-based data on the pharmacological, physiological, psychopharmacological, toxicological, and epidemiological characteristics of this molecule is non-existent. The aim of this paper is to remedy this situation.Methods:Recent literature (including ’grey‘) was searched to update what is known about 4F-EPH, especially its toxicity. This was supplemented by netnographic...

Supplemental Material, sj-xlsx-1-afp-10.1177_19253621221142480 for First Death Involving 4-Fluoroethylphenidate (4F-EPH): Case Report, User Experiences, and Review of the Related Literature by John Martin Corkery and Fabrizio Schifano in Academic Forensic Pathology

Background:4-Fluoroethylphenidate (4F-EPH) is a psychoactive substance, sold primarily over the Internet as a `research chemical'. Recreational and `functional' use of this drug has been reported by online user fora. Scientifically-based data on the pharmacological, physiological, psychopharmacological, toxicological, and epidemiological characteristics of this molecule is non-existent. The aim of this paper is to remedy this situation.Methods:Recent literature (including ’grey‘) was searched to update what is known about 4F-EPH, especially its toxicity. This was supplemented by netnographic...

Background:Approximately 50% of intensive care survivors experience persistent psychological symptoms. Eye-movement desensitisation and reprocessing (EMDR) is a widely recommended trauma-focussed psychological therapy, which has not been investigated systematically in a cohort of intensive care survivors: We therefore conducted a randomised pilot feasibility study of EMDR, using the Recent Traumatic Episode Protocol (R-TEP), to prevent psychological distress in intensive care survivors. Findings will determine whether it would be possible to conduct a fully-powered clinical effectiveness trial...

This material is a supplementary content video for a peer-reviewed journal article entitled “Experiments with Self-Organised Simulation of Movement of Infectious Aerosols in Buildings”, published in Sustainability Journal in June 2020, https://www.doi.org/10.3390/su12125204. It introduces simulations of movement of infectious aerosols generated by a sneeze. The simulations illustrate interactions of aerosols with still air, turbulent air, uniform air, as well as with ultraviolet radiation. They illustrate the issues related to airborne infection transmission and infection prevention....

The tree of life is the fundamental biological roadmap for navigating the evolution and properties of life on Earth, and yet remains largely unknown. Even angiosperms (flowering plants) are fraught with data gaps, despite their critical role in sustaining terrestrial life. Today, high-throughput sequencing promises to significantly deepen our understanding of evolutionary relationships. Here, we describe a comprehensive phylogenomic platform for exploring the angiosperm tree of life, comprising a set of open tools and data...

Supplemental material, sj-docx-1-inc-10.1177_17511437221136828 for A randomised pilot feasibility study of eye movement desensitisation and reprocessing recent traumatic episode protocol, to improve psychological recovery following intensive care admission for COVID-19 by Andrew Bates, Hannah Golding, Sophie Rushbrook, Elan Shapiro, Natalie Pattison, David S Baldwin, Michael P W Grocott and Rebecca Cusack in Journal of the Intensive Care Society

Background: The alarming growth of stimulant-involved deaths underscores the urgent need for states to expand existing opioid-specific approaches to intentionally reach and serve people who use stimulants. Recent permission from federal agencies has allowed states to spend grant funding that was previously restricted to opioid-related activities on approaches addressing stimulant use. Objectives: This manuscript describes the rationale, methods, and initial results supporting the implementation of Missouri’s recent stimulant-focused efforts – including previously-prohibited activities such as...

This document sets out the practical steps required for the further development and adoption of ePROMs that can benefit all people with kidney disease. At the centre of the report are core principles that include evidence, integration, implementation, and equality. The report also provides a rationale for these principles and delivery principles on how to take them forward.

Parkinson’s disease (PD) is the second most common neurodegenerative disorder producing a variety of motor and cognitive deficits with the causes remaining largely unknown. The gradual loss of the nigrostriatal pathway is currently considered the pivotal pathological event. To better understand the progression of PD and improve treatment management, defining the disease on a structural basis and expanding brain analysis to extra-nigral structures is indispensable. The anatomical complexity and the presence of neuromelanin, make the...

Background: Mosquito colony populations often show significant changes in their population genetic make-up compared to the field populations that were used as founding source. Most of the changes that have been reported are indicators of depletion in the overall genetic diversity of the colony populations. The Sterile Insect Techniques programme of mosquito control that is underway in Northern Sudan uses sterilized males produced from a laboratory-maintained colony population. The genetic diversity of an advanced generation...

Background Virtual Reality (VR) is an immersive computer-generated environment that provides a multi-sensory experience for the user. Modern technology allows the user to explore and interact with the virtual environment, offering opportunities for rehabilitation. The use of immersive VR in the management of musculoskeletal shoulder pain is relatively new and research is equired to demonstrate its feasibility and effectiveness in this field. Aim The aims of this study were, firstly, to explore physiotherapists’ beliefs and...