Data from: Barriers to gene flow in the marine environment: insights from two common intertidal limpet species of the Atlantic and MediterraneanAlexandra Sá Pinto, Madalena Simas Branco, Paulo Barros Alexandrino, Michaël C. Fontaine & Stuart J. E. Baird
Knowledge of the scale of dispersal and the mechanisms governing gene flow in marine environments remains fragmentary despite being essential for understanding evolution of marine biota and to design management plans. We use the limpets Patella ulyssiponensis and Patella rustica as models for identifying factors affecting gene flow in marine organisms across the North-East Atlantic and the Mediterranean Sea. A set of allozyme loci and a fragment of the mitochondrial gene cytochrome C oxidase subunit...
Data from: History of expansion and anthropogenic collapse in a top marine predator of the Black Sea estimated from genetic dataMichaël C. Fontaine, Alodie Snric, Alexandros Frantzis, Emmanuil Koutrakis, Bayram Öztürk, Ayaka A. Öztürk & Fréderic Austerlitz
Two major ecological transitions marked the history of the Black Sea after the last Ice Age. The first was the postglacial transition from a brackish-water to a marine ecosystem dominated by porpoises and dolphins, once this basin was reconnected back to the Mediterranean Sea (ca. 8,000 years B.P.). The second occurred during the last decades, when overfishing and hunting activities brought these predators close to extinction, deeply impacting the structure and dynamics of the ecosystem....
Data from: Migration patterns and changes in population biology associated with the worldwide spread of the oilseed rape pathogen Leptosphaeria maculansAzita Dilmaghani, Pierre Gladieux, Lilian Gout, Tatiana Giraud, Patrick C. Brunner, Anna Stachowiak, Marie-Hélène Balesdent & Thierry Rouxel
Pathogen introductions into novel areas can lead to the emergence of new fungal diseases of plants. Understanding the origin, introduction pathways, possible changes in reproductive system and population size of fungal pathogens is essential in devising an integrated strategy for the control of these diseases. We used minisatellite markers to infer the worldwide invasion history of the fungal plant pathogen Leptosphaeria maculans, which causes stem canker (blackleg) of oilseed and vegetable brassicas. Clustering analyses partitioned...
Data from: Virtual patients and sensitivity analysis of the Guyton model of blood pressure regulation: towards individualized models of whole-body physiologyRobert Moss, Thibault Grosse, Ivanny Marchant, Nathalie Lassau, François Gueyffier & S. Randall Thomas
Mathematical models that integrate multi-scale physiological data can offer insight into physiological and pathophysiological function, and may eventually assist in individualized predictive medicine. We present a methodology for performing systematic analyses of multi-parameter interactions in such complex, multi-scale models. Human physiology models are often based on or inspired by Arthur Guyton’s whole-body circulatory regulation model. Despite the significance of this model, it has not been the subject of a systematic and comprehensive sensitivity study. Therefore,...
Data from: Evolution of pathogenicity traits in the apple scab fungal pathogen in response to the domestication of its hostAmandine Lê Van, Pierre Gladieux, Christophe Lemaire, Amandine Cornille, Tatiana Giraud, Charles- Eric Durel, Valérie Caffier & Bruno Le Cam
Understanding how pathogens emerge is essential to bring disease-causing agents under durable human control. Here, we used cross-pathogenicity tests to investigate changes in life history traits of the fungal pathogen Venturia inaequalis associated with host-tracking during the domestication of apple and subsequent host range expansion on the wild European crabapple (Malus sylvestris). Pathogenicity of 40 isolates collected in wild and domesticated ecosystems were assessed on the domesticated apple, its central Asian main progenitor (M. sieversii)...
Data from: Polymorphism pattern at a Miniature Inverted-repeat Transposable Element locus downstream of the domestication gene Teosinte-branched1 in wild and domesticated pearl milletYann Dussert, Marie-Stanislas Remigereau, Michael C. Fontaine, Alodie Snirc, Ghayas Lakis, Solenn Stoeckel, Thierry Langin, Aboubakry Sarr, Thierry Robert, M.-S. Remigereau, M. C. Fontaine, T. Langin, S. Stoeckel, Y. Dussert, A. Snirc, G. Lakis, A. Sarr & T. Robert
Unraveling the mechanisms involved in adaptation to understand plant morphological evolution is a challenging goal. For crop species, identification of molecular causal polymorphisms involved in domestication traits are central to this issue. Pearl millet, a domesticated grass mostly found in semi-arid areas of Africa and India, is an interesting model to address this topic: the domesticated form shares common derived phenotypes with some other cereals such as a decreased ability to develop basal and axillary...
Data from: Comparing van Oosterhout and Chybicki-Burczyk methods of estimating null allele frequencies for inbred populationsPascal Campagne, Peter E. Smouse, Georges Varouchas, Jean-Francois Silvain, Bruno Le Rü, P. Campagne, J.-F. Silvain, B. Leru, G. Varouchas & P. E. Smouse
In spite of the usefulness of codominant markers in population genetics, the existence of null alleles raises challenging estimation issues in natural populations that are characterized by positive inbreeding coefficients (F > 0). Disregarding the possibility of F > 0 in a population will generally lead to overestimates of null allele frequencies. Conversely, estimates of inbreeding coefficients (F) may be strongly biased upwards (excess homozygotes), in the presence of nontrivial frequencies of null alleles. An...
University of Paris-Sud7
French National Centre for Scientific Research3
University of Valparaíso1
University of Melbourne1
French National Institute for Agricultural Research1
Paris Diderot University1
Institut Gustave Roussy1
University of Southern California1