35 Works

Socio-Economic Considerations and Potential Implications for Gene-Edited Crops

Karinne Ludlow, Stuart Smyth & Jose Falck-Zepeda

Clinician-researcher’s perspectives on clinical research during the COVID-19 pandemic

Sarah Silverberg, Lisa Puchalski-Ritchie, Nina Gobat, Alistair Nichol & Srinavas Murthy
Objectives: The outcome of well-performed clinical research is essential for evidence-based patient management during pandemics. However, conducting clinical research amidst a pandemic requires researchers to balance clinical and research demands. We seek to understand the values, experiences, and beliefs of physicians working at the onset of the COVID-19 pandemic in order to inform clinical research planning. We aim to understand whether pandemic settings affect physician comfort with research practices, and how physician experiences shape their...

Field-realistic antidepressant exposure disrupts group foraging dynamics in mosquitofish

Jake Martin, Minna Saaristo, Hung Tan, Michael Bertram, Venkatesh Nagarajan-Radha, Damian Dowling & Bob Wong
Psychoactive pollutants, such as antidepressants, are increasingly detected in the environment. Mounting evidence suggests that such pollutants can disrupt the behaviour of non-target species. Despite this, few studies have considered how the response of exposed organisms might be mediated by social context. To redress this, we investigated the impacts of two environmentally realistic concentrations of a pervasive antidepressant pollutant, fluoxetine, on foraging behaviour in fish (Gambusia holbrooki), tested individually or in a group. Fluoxetine did...

Analysis of ancestry heterozygosity suggests that hybrid incompatibilities in threespine stickleback are environment-dependent

Ken Thompson, Catherine Peichel, Diana Rennison, Matthew McGee, Arianne Albert, Timothy Vines, Anna Greenwood, Abigail Wark, Yaniv Brandvain, Molly Schumer & Dolph Schluter
Hybrid incompatibilities occur when interactions between opposite-ancestry alleles at different loci reduce the fitness of hybrids. Most work on incompatibilities has focused on those that are 'intrinsic', meaning they affect viability and sterility in the laboratory. Theory predicts that ecological selection can also underlie hybrid incompatibilities, but tests of this hypothesis using sequence data are scarce. In this article, we compiled genetic data for F2 hybrid crosses between divergent populations of threespine stickleback fish (Gasterosteus...

Delayed adaptive radiation among New Zealand stream fishes: joint estimation of divergence time and trait evolution in a newly delineated island species flock

Christine Thacker, James Shelley, William McCraney, Peter Unmack & Matthew McGee
Adaptive radiations are generally thought to occur soon after a lineage invades a region offering high levels of ecological opportunity. However, few adaptive radiations beyond a handful of exceptional examples are known, so a comprehensive understanding of their dynamics is still lacking. Here, we present a novel case of an island species flock of freshwater fishes with a radically different tempo of adaptive history than that found in many popular evolutionary model systems. Using a...

A non-coding indel polymorphism in the fruitless gene of Drosophila melanogaster exhibits antagonistically pleiotropic fitness effects

Michael Jardine, Filip Ruzicka, Charlotte Diffley, Kevin Fowler & Max Reuter
The amount of genetic variation for fitness within populations tends to exceed that expected under mutation-selection-drift balance. Several mechanisms have been proposed to actively maintain polymorphism and account for this discrepancy, including antagonistic pleiotropy (AP), where allelic variants have opposing effects on different components of fitness. Here we identify a non-coding indel polymorphism in the fruitless gene of Drosophila melanogaster and measure survival and reproductive components of fitness in males and females of replicate lines...

Bird community recovery following invasive tree removal

Roslyn Gleadow, Benjamin O'Leary, Martin Burd & Susanna Venn
Invasive plants can lead to significant changes in the abundance and diversity of the existing flora. Restoration programs, therefore, largely focus on the recovery of the vegetation. Faunal responses have received less attention. Here we examined whether or not bird communities recovered following removal of a native, invasive tree in South Eastern Australia with a view to evaluating whether this could be used as a tool for assessing the effectiveness of the remediation programs. Pittosporum...

Parasitism and host dispersal plasticity in an aquatic model system

Giacomo Zilio, Louise Nørgaard, Giovanni Petrucci, Nathalie Zeballos, Claire Gougat-Barbera, Emanuel Fronhofer & Oliver Kaltz
Dispersal is a central determinant of spatial dynamics in communities and ecosystems, and various ecological factors can shape the evolution of constitutive and plastic dispersal behaviours. One important driver of dispersal plasticity is the biotic environment. Parasites, for example, influence the internal condition of infected hosts and define external patch quality. Thus state-dependent dispersal may be determined by infection status and context-dependent dispersal by the abundance of infected hosts in the population. A prerequisite for...

Effectiveness of community-based health education and home support program to reduce blood pressure among patients with uncontrolled hypertension in Nepal: A cluster-randomized trial

Mahesh Kumar Khanal, Pratiksha Bhandari, Raja Ram Dhungana, Pratik Bhandari, Lal Rawal, Yadav Gurung, K. N. Paudel, Amit Singh, Surya Devkota & Barbora De Courten
Background: Hypertension is a major global public health problem. Elevated blood pressure can cause cardiovascular and kidney diseases. We assessed the effectiveness of health education sessions and home support programs in reducing blood pressure among patients with uncontrolled hypertension in a suburban community of Nepal. Methods: We conducted a community-based, open-level, parallel-group, cluster randomized controlled trial in Birendranagar municipality of Surkhet, Nepal. We randomly assigned four clusters (wards) into intervention and control arms. We provided...

Chronic insomnia and bed partner actigraphy data

Maia Angelova, Shitanshu Kusmakar, Chandan Karmakar, Ye Zhu, Sergiy Shelyag, Sean Drummond & Jason Ellis
The files contain seven nights of continuous actigraphy measurements of 40 subjects with chronic insomnia and their 40 bed partners. Wrist actigraphy was used, collected for one week using Respironics Actiwatch Spectrum Pro and Actiware software (Respironics, Bend, OR, USA), with movement counts were sampled in 60-second epochs. All recruited subjects wore the devices at all times during day and night. All subjects were free to move and were not prohibited from doing any activities...

Registration Year

  • 2021

Resource Types

  • Dataset
  • Text


  • Monash University
  • University of Melbourne
  • Deakin University
  • Department of Planning and Environment
  • University of Minnesota
  • University of British Columbia
  • Helmholtz Centre for Environmental Research
  • Sao Paulo State University
  • University of Washington
  • Dokuz Eylül University