Garvan Institute of Medical Research launched the Medical Genome Reference Bank, the world’s largest publicly available ‘genome bank’ specifically of healthy older people, an initiative of Garvan’s Kinghorn Centre for Clinical Genomics and NSW Health. Because it includes only the genomes of individuals over the age of 70 who have no history of major disease (cardiovascular disease, neurodegenerative disease or cancer), the Reference Bank is expected to be relatively free of genetic variants associated with...

Rationale:The evidence base for acute post-stroke rehabilitation is inadequate and global guideline recommendations vary.Aim:To define optimal early mobility intervention regimens for ischemic stroke patients of mild and moderate severity.Hypotheses:Compared with a prespecified reference arm, the optimal dose regimen(s) will result in more participants experiencing little or no disability (mRS 0–2) at 3 months post-stroke (primary), fewer deaths at 3 months, fewer and less severe complications during the intervention period, faster recovery of unassisted walking, and...

The supporting material contains data and theoretical derivations that are not given in the manuscript, and it is a supplement to this work.

Multi-omics datasets represent distinct aspects of the central dogma of molecular biology. Such high-dimensional molecular profiles pose challenges to data interpretation and hypothesis generation. ActivePathways is an integrative method that discovers significantly enriched pathways across multiple datasets using statistical data fusion, rationalizes contributing evidence and highlights associated genes. As part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38 tumor types, we integrated...

Pre-print version of a published paper.
Please cite as: Selwyn, N. (2023). Digital degrowth: toward radically sustainable education technology. Learning, Media and Technology https://doi.org/10.1080/17439884.2022.2159978

Abstract: This paper outlines how ideas of ‘degrowth’ might be used to reimagine sustainable forms of education technology. In essence, degrowth calls for a proactive renewal of technology use around goals of voluntary simplicity and slowing down, community-based coproduction and sharing, alongside conscious minimalization of resource consumption. As...

The geographical range of the mosquito vector for many human disease-causing viruses, Aedes aegypti, is expanding, in part owing to changing climate. The capacity of this species to adapt to thermal stress will affect its future distributions. It is unclear how much heritable genetic variation may affect the upper thermal limits of mosquito populations over the long term. Nor are the genetic pathways that confer thermal tolerance fully understood. In the short term, cells induce...

Maiwa yak is a special breed of animal living on the Qinghai-Tibet Plateau, which has great economic value, but its fertility rate is low. The corpus luteum (CL) is a temporary tissue that plays a crucial role in maintaining the physiological cycle. However, little is known about the transcriptome profile in Maiwa yak CL. In the present study, the transcriptome of Maiwa yak CL at early (EYCL), middle (MYCL) and late-stages (LYCL) was studied employing...

ABSTRACT Introduction By improving the material level of life, the amount of exercise of adolescents is decreasing, leading the muscular strength and cardiorespiratory resistance to also decrease instead of increase. Therefore, it is urgent to present effective training methods in physical education teaching to benefit adolescents’ quality of life. Objective Study the effect of table tennis training on musculature and cardiorespiratory endurance in young students. Methods 60 students from grade 7 of a high school...

In order to understand the research status of the relationship between health communication and doctor-patient relationship, and to explore a new path of the impact of health communication on doctor-patient relationship, this paper adopted qualitative methods to quantize the literature over the past 10 years in the Web of Science database and carried out Co-Authorship Analysis, Co-Citation Analysis and Co-Occurrence Analysis based on CiteSpace. In addition, according to the results of bibliometric research, self-designed questionnaires...

Following substantial domestic and family violence (DFV) reforms in Australia in recent years, the identification of victim-survivors is increasingly embedded across service system responses. In contrast, while men using DFV often have diverse service system contact for co-occurring issues, their use of DFV is often not identified.
This mixed-methods study examines current screening and risk assessment practices for DFV perpetration in service systems that frequently encounter men who may be using DFV, including mental...

Spatially Resolved Transcriptomics Exploration in 3D desktop and Virtual Environments with VR-Omics – Additional Resources.

This repository contains cleaning and analytical RMarkdown files, RProject file, and analysable data from our study on the RTW Act, which replaced South Australia's workers' compensation system.
Analysable data are aggregations of individual-level claims data. We are unable to include the individual-level claims data because they contain identifiable information.

There is strong evidence of the adverse effects of fine particulate matter with diameters that are 2.5 micrometres and smaller (PM2.5) on lung cancer, but the impact of PM2.5 at other body sites remains scarce. In this thesis, long-term PM2.5 exposure in Brazil was observed to be associated with increased cancer hospitalizations, mortality and years of life lost from most cancer sites. Cancer accounts for a large proportion of loss of life expectancy attributable to...

ObjectivesPerturbations of the intestinal microbiota have been associated with mental health disorders, including major depressive disorder (MDD). Therefore, faecal microbiota transplantation (FMT) holds promise as a microbiota-modulating treatment for MDD. Yet, to date, there are no published controlled studies evaluating the use of FMT for MDD. This study aimed to address this gap by evaluating the feasibility, acceptability, and safety of FMT for MDD.MethodsThe study was an 8-week, double-blind, 2:1 parallel group, randomized controlled pilot...

This dataset contains the metadata and figures that were used to prepare the figures for the above-mentioned journal paper

Supplemental material, sj-pdf-1-imr-10.1177_03000605221147434 for The inflammatory cytokine profiles and ocular biometric characteristics of primary angle-closure glaucoma by Hong-Bo Zeng, Jun-Di Jiang, Rong Li, Jian Li, Wen-Juan Zeng, Xiong-Kai Li, Bin Hu, Fei Zhou, Hai-Ying Yu, Jian-Guo Xie, Zhi-Neng Ning and Xian Wang in Journal of International Medical Research

ObjectiveTo investigate the pathogenesis of primary angle-closure disease (PACG) by measuring the anatomical structures of the anterior and posterior segments of the eye and inflammatory markers in the peripheral blood.MethodsThis case–control study enrolled patients diagnosed with acute PACG (APACG) and chronic PACG (CPACG). It also enrolled control subjects without PACG. The anterior and posterior anatomical features were measured in all study participants. The levels of interleukin (IL)-6, tumour necrosis factor-α and the neutrophil-to-lymphocyte ratio (NLR)...

Presentation at AARE Conference - 2 December 2021
How research engaged are Australian school educators?

Presentation at AARE Conference - 2 December 2021
How research engaged are Australian school educators?

This Stata .do file provides the code used to analyse the data extracted and coded from systematic reviews included in the paper: Cumpston MS, Brennan SE, Ryan R, McKenzie JE. 2023. Statistical synthesis methods other than meta-analysis are commonly used, but are seldom specified: a survey of systematic reviews of interventions Input file: Synthesis methods data file: Cumpston_et_al_2022_other_synthesis_methods.xlsx (https://doi.org/10.26180/20785396) Associated file: Synthesis methods data dictionary (https://doi.org/10.26180/20785948) Study protocol: Cumpston MS, McKenzie JE, Thomas J and...

A consortium of recreational fishing advocates, fisheries managers, and marine scientists from Monash University, Victorian Recreational Fishing Peak Body (VRFish), Flinders University, and the Victorian Fisheries Authority collaborated to create best-practice capture, handling, and release guidelines for recreational fishing of sharks and rays. The guidelines were communicated to the recreational fishing community in southern Australia by creating of a multi-media extension campaign called Shark Mates. Informational resources, such as a best-practice guidelines booklet, six YouTube...

This is a composition for instrument, voice and electronics, composed in 2018. Commissioned by Callum G'Froerer
PROGRAM NOTE
In 2016, Australian author Richard Flanagan made a statement in a response to the Australian Government’s policy on the treatment of refugees arriving in Australia by boat, which involves detention. "Their lives are stripped of meaning." In this piece, the vocalist sings these words, but they become incomprehensible as they are separated out over the 8...

Supplementary material: A pilot case crossover study of the use of padded headgear in junior Australian football

Contains numerical XRD and LA-ICP-MS data of zebra rock as displayed in figures (Microsoft Excel format), as well as all raw XRD .brml files, and XFM images.

Supplemental material, sj-pdf-1-imr-10.1177_03000605231154749 for Implementation effect of a hierarchical pharmaceutical service pattern in patients with systemic lupus erythematosus by Yinhua Gong, Wei Wei, Wei Zhang, Qiang Han and Chunge Zhang in Journal of International Medical Research