3 Works

Data from: Continuum of vasodilator stress from rest to contrast medium to adenosine hyperemia for fractional flow reserve assessment

Nils P. Johnson, Allen Jeremias, Frederik M. Zimmermann, Julien Adjedj, Nils Witt, Barry Hennigan, Bon-Kwon Koo, Akiko Maehara, Mitsuaki Matsumura, Emanuele Barbato, Giovanni Esposito, Bruno Trimarco, Gilles Rioufol, Seung-Jung Park, Hyoung-Mo Yang, Sérgio B. Baptista, George S. Chrysant, Antonio M. Leone, Colin Berry, Bernard De Bruyne, K. Lance Gould, Richard L. Kirkeeide, Keith G. Oldroyd, Nico H. J. Pijls, William F. Fearon … & Nico H.J. Pijls
OBJECTIVES: We compared the diagnostic performance with adenosine-derived fractional flow reserve (FFR) #0.8 of contrast-based FFR (cFFR), resting distal pressure (Pd)/aortic pressure (Pa), and the instantaneous wave-free ratio (iFR). BACKGROUND: FFR objectively identifies lesions that benefit from medical therapy versus revascularization. However, FFR requires maximal vasodilation, usually achieved with adenosine. Radiographic contrast injection causes submaximal coronary hyperemia. Therefore, intracoronary contrast could provide an easy and inexpensive tool for predicting FFR. METHODS: We recruited patients undergoing...

Data from: Quantitative multi-parametric magnetic resonance imaging of tumor response to photodynamic therapy

Tom J.L. Schreurs, Stefanie J. Hectors, Igor Jacobs, Holger Grüll, Klaas Nicolay, Gustav J. Strijkers & Tom J. L. Schreurs
Objective: The aim of this study was to characterize response to photodynamic therapy (PDT) in a mouse cancer model using a multi-parametric quantitative MRI protocol and to identify MR parameters as potential biomarkers for early assessment of treatment outcome. Methods: CT26.WT colon carcinoma tumors were grown subcutaneously in the hind limb of BALB/c mice. Therapy consisted of intravenous injection of the photosensitizer Bremachlorin, followed by 10 min laser illumination (200 mW/cm2) of the tumor 6...

Data from: A 45-second self-test for cardiorespiratory fitness: heart rate-based estimation in healthy individuals

Francesco Sartor, Matteo Bonato, Gabriele Papini, Andrea Bosio, Rahil A. Mohammed, Alberto G. Bonomi, Jonathan P. Moore, Giampiero Merati, Antonio La Torre & Hans-Peter Kubis
Cardio-respiratory fitness (CRF) is a widespread essential indicator in Sports Science as well as in Sports Medicine. This study aimed to develop and validate a prediction model for CRF based on a 45 second self-test, which can be conducted anywhere. Criterion validity, test re-test study was set up to accomplish our objectives. Data from 81 healthy volunteers (age: 29 ± 8 years, BMI: 24.0 ± 2.9), 18 of whom females, were used to validate this...

Registration Year

  • 2016
    3

Resource Types

  • Dataset
    3

Affiliations

  • Eindhoven University of Technology
    3
  • Bangor University
    1
  • INTEGRIS Baptist Medical Center
    1
  • Stanford University
    1
  • Columbia University
    1
  • University of Glasgow
    1
  • University of Milan
    1
  • Seoul National University Hospital
    1
  • University of Pisa
    1
  • Catholic University of the Sacred Heart
    1