28 Works

Effectiveness and feasibility of convalescent blood transfusion to reduce COVID-19 fatality ratio

Xi Huo, Xiaodan Sun, Nicola Bragazzi & Jianhong Wu
As of December 2020, COVID-19 has spread all over the world with more than 81 million cases and more than 1.8 million deaths. The rapidly increasing number of patients mandates the consideration of potential treatments for patients under severe and critical conditions. Convalescent plasma (CP) treatment refers to the approach of infusing patients with plasma from recently recovered patients. CP appears to be a possible therapeutic option to manage patients suffering from severe or even...

The mechanism underlying transient weakness in myotonia congenita

Jessica Myers, Mark Rich, Kirsten Denman, Chris DuPont, Ahmed Hawash, Kevin Novak, Andrew Koesters, Manfred Grabner, Anamika Dayal & Andrew Voss
In addition to the hallmark muscle stiffness, patients with recessive myotonia congenita (Becker disease) experience debilitating bouts of transient weakness that remain poorly understood despite years of study. We made intracellular recordings from muscle of both genetic and pharmacologic mouse models of Becker disease to identify the mechanism underlying transient weakness. Our recordings reveal transient depolarizations (plateau potentials) of the membrane potential to -25 to -35 mV in the genetic and pharmacologic models of Becker...

Multiple mutualism effects generate synergistic selection and strengthen fitness alignment in the interaction between legumes, rhizobia, and mycorrhizal fungi

Michelle Afkhami, Maren Friesen & John Stinchcombe
Nearly all organisms participate in multiple mutualisms, and complementarity within these complex interactions can result in synergistic fitness effects. However, it remains largely untested how multiple mutualisms impact eco-evolutionary dynamics in interacting species. We tested how multiple microbial mutualists-- N-fixing bacteria and mycorrrhizal fungi-- affected selection and heritability of traits in their shared host plant (Medicago truncatula), as well as fitness alignment between partners. Our results demonstrate for the first time that multiple mutualisms synergistically...

Effects of cucurbituril size on the binding of a lutidine guest

Angel E. Kaifer, Vladimir Sindelar & Jan Svec
Six- and seven-membered cucurbiturils form inclusion complexes with a lutidine derivative. These inclusion complexes differ in the binding mode, stability, kinetics of complexation, and sensitivity toward basic media.

Oceanic Advection Controls Mesoscale Mixed Layer Heat Budget and Air-sea Heat Exchange in the Southern Ocean

Yu Gao, Igor Kamenkovich, Natalie Perlin & Ben Kirtman
We analyze the role of mesoscale heat advection in the Southern Ocean mixed layer (ML) heat budget using a regional high-resolution coupled model, with realistic atmospheric forcing and an idealized ocean component. In order to test if the overall current speed affect our conclusion, the simulations are carried out in two distinct cases: one with overall strong current (SC case) and the other with overall weak current (WC case). Mesoscale currents are defined with two...

Coexistence within an endangered predator–prey community in California vernal pools

Arianne F. Messerman, Adam G. Clause, Shantel V. L. Catania, H. Bradley Shaffer & Christopher A. Searcy
1. Globally endangered ecosystems, like ephemeral wetlands, are often critical habitat for multiple interacting imperiled species. To conserve this biodiversity, managers must consider both species-specific resource requirements and mechanisms for endangered species coexistence under variable habitat conditions. 2. We examined communities native to California playa pools, ephemeral wetlands that have declined by >90% from their historic extent. Specifically, we describe the diet of a federally Threatened amphibian (Ambystoma californiense), and characterize interactions between this amphibian...

A Case Study on the Medical Library Association’s 2019 Communities Transition Qualitative Data Set

Kathryn Houk, Kelsa Bartley, Jane Morgan-Daniel & Elaina Vitale
In 2019, the Medical Library Association (MLA) adopted a new model of community governance and participation, referred to as the MLA Communities Transition. The Communities Transition was the culmination of long-ranging plans by MLA to support two of its strategic goals: Diversity and Inclusion, and Communities. The reorganization aimed to strengthen MLA member communities, better support programming, reduce administrative overhead, and attract new members. The 2019 - 2020 MLA Rising Stars cohort was tasked to...

“Don’t Go, Don’t Buy”: Understanding the Motivations of the Anti-Japan Boycott Movement in South Korea During an International Conflict

Yeunjae Lee & Myoung-Gi Chon

Variation in leaf temperatures of tropical and subtropical trees are related to leaf thermoregulatory traits and not geographic distributions dataset

Olga Tserej & Kenneth Feeley
To predict the effects of global warming on plants, previous studies have investigated how the distributions and physiological performances of plants relate to environmental temperatures. This approach implicitly assumes that leaf temperatures are tightly linked with regional air temperatures. However, the thermoregulatory behaviors and physical properties of leaves can differ greatly between species, leading to different plants having different leaf temperatures even when occurring under similar conditions. It is important to understand this variation in...

Determination of the Purity of Cucurbit[n]uril (n = 7, 8) Host Samples

Angel E. Kaifer & Song Yi
The formation of highly stable inclusion complexes in aqueous solution between the organometallic cobaltocenium cation (Cob+) and the hosts cucurbit[7]uril (CB7) and cucurbit[8]uril (CB8) was used to develop a simple method, based on UV–vis titrations, to assay the purity of samples of these two hosts. The equilibrium association constant (K) of the Cob+@CB7 complex had been previously reported by our group as 5.7 × 109 M–1 at 25 °C in 50 mM sodium acetate medium....

Transforming Metadata into Linked Data to Improve Digital Collection Discoverability: A CONTENTdm Pilot Project

Greta Bahnemann, Michael J. Carroll, Paul Clough, Mario Einaudi, Chatham Ewing, Jeff Mixter, Jason Roy, Holly Tomren, Bruce Washburn & Elliot Williams

Adaptive introgression of the beta-globin cluster in two Andean waterfowl

Allie Graham & Kevin McCracken
Introgression of alleles has emerged as an important avenue for genetic adaptation in both plant and animal populations. In vertebrates, adaptation to hypoxic high-altitude environments involves the coordination of multiple molecular and cellular mechanisms, including selection on the Hypoxia-Inducible Factor (HIF) pathway and the blood-O2 transport protein hemoglobin (Hb). In two Andean duck species, a striking DNA sequence similarity reflecting identity by descent is present across the ~20 kb b-globin cluster including both embryonic (HBE)...

Base-substitution mutation rate across the nuclear genome of Alpheus snapping shrimp and the timing of isolation by the Isthmus of Panama

Katherine Silliman, Jane Indorf, Nancy Knowlton, William Browne & Carla Hurt
The formation of the Isthmus of Panama and final closure of the Central American Seaway (CAS) provides an independent calibration point for examining the rate of DNA substitutions. This vicariant event has been widely used to estimate the substitution rate across mitochondrial genomes and to date evolutionary events in other taxonomic groups. Nuclear sequence data is increasingly being used to complement mitochondrial datasets for phylogenetic and evolutionary investigations; these studies would benefit from information regarding...

Binding of bambusuril with bipyridinium guests in water

Kristina Sleziakova, Mehdi Rashvand Avei, Angel E. Kaifer & Vladimir Sindelar
(2018). Binding of bambusuril with bipyridinium guests in water. Supramolecular Chemistry: Vol. 30, SI: ISMSC, pp. 832-837.

Data from: Positive allosteric modulation of the α7 nicotinic acetylcholine receptor as a treatment for cognitive deficits after traumatic brain injury

David J. Titus, Timothy Johnstone, Nathan H. Johnson, Sidney H. London, Meghana Chapalamadugu, Derk Hogenkamp, Kelvin W. Gee & Coleen M. Atkins
Cognitive impairments are a common consequence of traumatic brain injury (TBI). The hippocampus is a subcortical structure that plays a key role in the formation of declarative memories and is highly vulnerable to TBI. The α7 nicotinic acetylcholine receptor (nAChR) is highly expressed in the hippocampus and reduced expression and function of this receptor are linked with cognitive impairments in Alzheimer’s disease and schizophrenia. Positive allosteric modulation of α7 nAChRs with AVL-3288 enhances receptor currents...

Interindividual plasticity in metabolic and thermal tolerance traits from populations subjected to recent anthropogenic heating

Melissa Drown, Amanda DeLiberto, Moritz Ehrlich, Douglas Crawford & Marjorie Oleksiak
To better understand temperature’s role in the interaction between local evolutionary adaptation and physiological plasticity, we investigated acclimation effects on metabolic performance and thermal tolerance among natural Fundulus heteroclitus populations from different thermal environments. F. heteroclitus populations experience large daily and seasonal temperature variations, as well as local mean temperature differences across their large geographic cline. In this study, we focus on three populations: one locally heated (32°C) by thermal effluence (TE) from the Oyster...

Comparison of adult census size and effective population size support the need for continued protection of two Solomon Island endemics

Sarah A. Cowles, Brian C. Weeks, Lindsey Perrin, Nancy Chen & J. Albert C. Uy
Because a population’s ability to respond to rapid change is dictated by standing genetic variation, we can better predict a population’s long-term viability by estimating and then comparing adult census size (N) and effective population size (Ne). However, most studies only measure N or Ne, which can be misleading. Using a combination of field and genomic sequence data, we here estimate and compare N and Ne in two range-restricted endemics of the Solomon Islands. Two...

Area and Timing data and R script for: 3D scanning as a tool to measure growth rates of live coral microfragments used for coral reef restoration

Hanna Koch, Bailey Wallace, Allyson DeMerlis, Abigail Clark & Robert Nowicki
Rapid and widespread declines in coral health and abundance have driven increased investments in coral reef restoration interventions to jumpstart population recovery. Microfragmentation, an asexual propagation technique, is used to produce large numbers of corals for research and restoration. As part of resilience-based restoration, coral microfragments of different genotypes and species are exposed to various stressors to identify candidates for propagation. Growth rate is one of several important fitness-related traits commonly used in candidate selection,...

Ecological and biogeographic processes drive the proteome evolution of snake venom

Tuany Siqueira-Silva, Luiz Lima, Jônatas Chaves-Silveira, Talita Amado, Julian Naipauer, Pablo Riul & Pablo Martinez
The emergence of venom is an evolutionary innovation that favored the diversification and survival of snakes. The composition of snake venoms is known in detail from venom gland proteomic data. However, there is still a gap of knowledge about the forces that lead to the expression of different toxins in different proportions in the venom cocktail across space and time. LOCATION World. TIME PERIOD Modern. MAJOR TAXA STUDIED Elapidae and Viperidae. We integrated proteomic data...

Aboveground carbon stocks and dynamics in Andean forests

Alvaro Duque, Miguel Peña, Francisco Cuesta, Sebastián González-Caro, Peter Kennedy, Oliver Phillips, Marco Calderón, Cecilia Blundo, Julieta Carilla, Leslie Cayola, William Farfán-Ríos, Alfredo Fuentes, Ricardo Grau, Jürgen Homeier, María I. Loza-Rivera, Jonathan A. Myers, Oriana Osinaga-Acosta, Manuel Peralvo, Esteban Pinto, Sassan Saatchi, Miles Silman, J. Sebastián Tello, Andrea Terán-Valdez & Kenneth J. Feeley
This dataset (Andean_AGB.xlsx) has the data employed in the paper entitled Old-growth Andean forests as globally important carbon sinks and future carbon refuges. The data was compiled as the results of the work of several research teams spread out across the Andean region. The information available here has data about aboveground carbon stocks and dynamics and the main explanatory variables, such as climate and symbiotic root associations.

Complexation of Ferrocene Derivatives by the Cucurbit[7]uril Host:  A Comparative Study of the Cucurbituril and Cyclodextrin Host Families

Woo Sung Jeon, Kwangyul Moon, Sang Hyun Park, Hyungpil Chun, Young Ho Ko, Jin Yong Lee, Eun Sung Lee, S. Samal, N. Selvapalam, Mikhail V. Rekharsky, Vladimir Sindelar, David Sobransingh, Yoshihisa Inoue, Angel E. Kaifer & Kimoon Kim
The formation of inclusion complexes between cucurbit[7]uril (CB[7]) and ferrocene and its derivatives has been investigated. The X-ray crystal structure of the 1:1 inclusion complex between ferrocene and CB[7] revealed that the guest molecule resides in the host cavity with two different orientations. Inclusion of a set of five water-soluble ferrocene derivatives in CB[7] was investigated by 1H NMR spectroscopy and calorimetric and voltammetric techniques. Our data indicate that all neutral and cationic guests form...

Diversity Residency Toolkit

Kalani Adolpho, Maya Bergamasco, Ana Corral, , , & Liburd Tavernier W

Dataset S1 - Noelaerhabdaceae organic carbon isotope culture data compilation

Samuel Phelps, Gwenn Hennon, Sonya Dyhrman, María Hernández-Limón, Olivia Williamson & Pratigya Polissar
The carbon isotope fractionation in algal organic matter (Ep), including the long-chain alkenones produced by the coccolithophorid family Noelaerhabdaceae, is used to reconstruct past atmospheric CO2 levels. The conventional proxy linearly relates Ep to changes in cellular carbon demand relative to diffusive CO2 supply, with larger Ep values occurring at lower carbon demand relative to supply (i.e. abundant CO2). However, the response of Gephyrocapsa oceanica, one of the dominant alkenone producers of the last few...

First Atlantic satellite tracks of lost years green turtles support the importance of the Sargasso Sea as a sea turtle nursery

Katherine Mansfield, Jeanette Wyneken & Jiangang Luo
In-water behaviour and long-term movements of oceanic-stage juvenile sea turtles are not well described or quantified. This is due to technological or logistical limitations of tracking small, fast-growing animals across long distances and time-periods within marine habitats. Here we present the first long-term offshore tracks of oceanic green turtles (Chelonia mydas) in western North Atlantic waters. Using a tag attachment technique developed specifically for young (<1 year old) green turtles, we satellite tracked 21 oceanic-stage...

Registration Year

  • 2021
    28

Resource Types

  • Dataset
    25
  • Text
    2
  • Other
    1

Affiliations

  • University of Miami
    28
  • Masaryk University
    4
  • Auburn University
    2
  • Harvard University
    2
  • Columbus State University
    1
  • Wright-Patterson Air Force Base
    1
  • Consortium for Sustainable Development of the Andean Ecoregion
    1
  • Texas State Library and Archives Commission
    1
  • University of Michigan-Ann Arbor
    1
  • Temple University
    1