29 Works

Data from: Ranked tree shapes, nonrandom extinctions and the loss of phylogenetic diversity

Odile Maliet, Fanny Gascuel & Amaury Lambert
Phylogenetic diversity (PD) is a measure of the evolutionary legacy of a group of species, which can be used to define conservation priorities. It has been shown that an important loss of species diversity can sometimes lead to a much less important loss of PD, depending on the topology of the species tree and on the distribution of its branch lengths. However, the rate of decrease of PD strongly depends on the relative depths of...

Data from: Delimiting species of marine gastropods (Turridae, Conoidea) using RAD-sequencing in an integrative taxonomy framework

Jawad Abdelkrim, Laetitia Aznar-Cormano, Barbara Buge, Alexander Fedosov, Yuri Kantor, Paul Zaharias & Nicolas Puillandre
Species delimitation in poorly-known and diverse taxa is usually performed based on monolocus, DNA barcoding-like approaches, while multilocus data are often used to test alternative species hypotheses in well-studied groups. We combined both approaches to delimit species in the Xenuroturris / Iotyrris complex, a group of venomous marine gastropods from the Indo-Pacific. First, COI sequences were analyzed using three methods of species delimitation, ABGD, PTP and GMYC to propose primary species hypotheses (PSH). Second, RAD-seq...

Data from: The increasing disconnection of primary biodiversity data from specimens: how does it happen and how to handle it?

Julien Troudet, Régine Vignes-Lebbe, Philippe Grandcolas & Frédéric Legendre
Abstract.—Primary biodiversity data represent the fundamental elements of any study in systematics and evolution. They are, however, no longer gathered as they used to be and the mass-production of observation-based occurrences is overthrowing the collection of specimen-based occurrences. Although this change in practice is a major upheaval with significant consequences in the study of biodiversity, it remains understudied and has not attracted yet the attention it deserves. Analyzing 536 million occurrences from the Global Biodiversity...

Data from: Some like it hot: from individual to population responses of an arboreal arid-zone gecko to local and distant climate

Annegret Grimm-Seyfarth, Jean-Baptiste Mihoub, Bernd Gruber & Klaus Henle
Accumulating evidence has demonstrated considerable impact of climate change on biodiversity, with terrestrial ectotherms being particularly vulnerable. While climate-induced range shifts are often addressed in the literature, little is known about the underlying ecological responses at individual and population levels. Using a 30-year monitoring study of the long-living nocturnal gecko Gehyra variegata in arid Australia, we determined the relative contribution of climatic factors acting locally (temperature, rainfall) or distantly (La Nin᷉a induced flooding) on ecological...

Data from: Effects of partial selfing on the equilibrium genetic variance, mutation load and inbreeding depression under stabilizing selection

Diala Abu Awad & Denis Roze
The mating system of a species is expected to have important effects on its genetic diversity. In this paper, we explore the effects of partial selfing on the equilibrium genetic variance Vg, mutation load L and inbreeding depression δ under stabilizing selection acting on a arbitrary number n of quantitative traits coded by biallelic loci with additive effects. When the U/n ratio is low (where U is the total haploid mutation rate on selected traits)...

Data from: A new tealliocaridid crustacean from the Late Carboniferous of North China and its biogeographic implications

Qiang Yang, Pierre Gueriau, Sylvain Charbonnier, Dong Ren, Olivier Béthoux & Sylvain Charbonner
A new tealliocaridid eumalacostracan is described from the Late Carboniferous Tupo Formation (Ningxia, China). Laevitealliocaris xiaheyanensis gen. et sp. nov. is represented by a single specimen, characterised by the possession of a short rostrum without dorsal spine, a short postcervical carina and only one weak branchial carina, both tuberculate, and a short sixth pleonal somite. This is the first unequivocal record of tealliocaridids outside Euramerica, which occurrence along the eastern inner margin of the Palaeotethys...

Data from: When Darwin’s special difficulty promotes diversification in insects

Frédéric Legendre & Fabien L. Condamine
Eusociality, Darwin’s special difficulty, has been widely investigated but remains a topic of great debate in organismal biology. Eusocial species challenge existing theories, and the impact of highly integrated societies on diversification dynamics is controversial with opposing assertions and hypotheses in the literature. Here, using phylogenetic approaches in termites – the first group that has evolved eusociality – we assessed the fundamental prediction that eusocial lineages have higher diversification rates than non-eusocial clades. We found...

Data from: Evaluating alternative explanations for an association of extinction risk and evolutionary uniqueness in multiple insular lineages.

Ben H. Warren, Oskar Hagen, Florian Gerber, Christophe Thebaud, Emmanuel Paradis & Elena Conti
Studies in insular environments have often documented a positive association of extinction risk and evolutionary uniqueness (i.e. how distant a species is from its closest living relative). However, the cause of this association is unclear. One explanation is that species threatened with extinction are evolutionarily unique because they are old, implying that extinction risk increases with time since speciation (age-dependent extinction). An alternative explanation is that such threatened species are last survivors of clades that...

Data from: The sex chromosome system can influence the evolution of sex-biased dispersal

Thomas Brom, Manuel Massot & David Laloi
Sex-biased dispersal is a much-discussed feature in literature on dispersal. Diverse hypotheses have been proposed to explain the evolution of sex-biased dispersal, a difference in dispersal rate or dispersal distance between males and females. An early hypothesis has indicated that it may rely on the difference in sex chromosomes between males and females. However, this proposal was quickly rejected without a real assessment. We propose a new perspective on this hypothesis by investigating the evolution...

Data from: Serial homology and correlated characters in morphological phylogenetics: modeling the evolution of dental crests in placentals

Guillaume Billet & Jérémie Bardin
Accurate modeling of the complexity of morphological evolution is crucial for morphological phylogenetics and for performing tests on a wide variety of evolutionary scenarios. In this context, morphological integration and the problem of correlated categorical characters represent a major challenge. In particular, the magnitude and implications of correlations among serially homologous structures such as teeth have been much debated but were never tested statistically within a broad phylogenetic context. Here, we present a large-scale empirical...

Data from: Embryonal life histories: desiccation plasticity and diapause in the Argentinean pearlfish Austrolebias bellottii

Tom J.M. Van Dooren, Irma Varela-Lasheras & Tom J. M. Van Dooren
Embryos of annual killifish diapause in soil egg banks while ponds are dry. Their rates of development and survival in different developmental stages determine the numbers and stages of embryos at rewetting. In the Argentinean pearlfish Austrolebias bellottii, we investigated plasticity for desiccation in such embryonal life history components across phases of mild desiccation and rewetting and also effects of life history on hatching. In comparison to non-annuals, our data suggest that incidences of diapause...

Data from: Resveratrol supplementation reduces oxidative stress and modulates the immune response in free-living animals during a viral infection

Manrico Sebastiano, Marcel Eens, Simone Messina, Hamada Ablelgawad, Kévin Pineau, Gerrit T.S. Beemster, Olivier Chastel, David Costantini, Hamada AbdElgawad & Gerrit T. S. Beemster
1. Diet quality may have an important effect on the regulation of oxidative status and the immune system during an infectious disease. However, the relationship among intake of specific dietary molecules, an individual’s oxidative status and the occurrence and progress of a viral disease remains almost unexplored in free-living organisms. 2. Here, we study a wild, long-lived animal, the Magnificent frigatebird Fregata magnificens to investigate: i) the differences in a number of physiological traits (biomarkers...

Data from: Molecular evidence for the paraphyly of Scolecophidia and its evolutionary implications

Aurélien Miralles, Julie Marin, Damien Markus, Anthony Herrel, Blair S. Hedges & Nicolas Vidal
The phylogenetic relationships between the three main clades of worm snakes remain controversial. This question is, however, crucial to elucidate the origin of the successful snake radiation, as these burrowing and miniaturized wormlike organisms represent the earliest branching clades among the snake tree. The present molecular phylogenetic study, intended to minimize the amount of missing data, provides fully resolved inter-subfamilial relationships among Typhlopidae. It also brings robust evidence that worm snakes (Scolecophidia) are paraphyletic, with...

Data from: Predictors of alcohol responsiveness in dystonia

Johanna Junker, Valerie Brandt, Brian D. Berman, Marie Vidailhet, Emmanuel Roze, Anne Weissbach, Cynthia Comella, Irene A. Malaty, Joseph Jankovic, Mark S. LeDoux, Alfredo Berardelli, Richard Barbano, Stephen G. Reich, Joel S. Perlmutter, Hyder A. Jinnah & Norbert Brüggemann
Objective: To determine predictors of alcohol responsiveness in a large cohort of dystonia patients. Methods: 2159 participants with dystonia were prospectively enrolled in the cross-sectional Dystonia Coalition multicenter study. Patients with secondary, combined or confirmed genetic dystonia (total n=164) or unknown alcohol responsiveness (n= 737) were excluded. Patients answered a standardized questionnaire and were clinically examined using a standardized video protocol and the Burke-Fahn-Marsden Dystonia Rating Scale. Alcohol responsiveness was determined by patients’ self-report. Results:...

Data from: Melanin-based colouration and host-parasite interactions under global change

Jessica Côte, Amandine Boniface, Simon Blanchet, Andrew Hendry, Julien Gasparini & Lisa Jacquin
The role of parasites in shaping melanin-based colour polymorphism, and the consequences of colour polymorphism for disease resistance, remain debated. Here we review recent evidence of the links between melanin-based colouration and the behavioural and immunological defences of vertebrates against their parasites. First we propose that (1) differences between colour morphs can result in variable exposure to parasites, either directly (certain colours might be more or less attractive to parasites) or indirectly (variations in behaviour...

Data from: Unraveling the seasonal epidemiology of pneumococcus

Matthieu Domenech De Cellès, Hélène Arduin, Daniel Lévy-Bruhl, Scarlett Georges, Cécile Souty, Didier Guillemot, Laurence Watier & Lulla Opatowski
Infections caused by Streptococcus pneumoniae—including invasive pneumococcal diseases (IPDs)—remain a significant public health concern worldwide. The marked winter seasonality of IPDs is a striking, but still enigmatic aspect of pneumococcal epidemiology in nontropical climates. Here we confronted age-structured dynamic models of carriage transmission and disease with detailed IPD incidence data to test a range of hypotheses about the components and the mechanisms of pneumococcal seasonality. We find that seasonal variations in climate, influenza-like illnesses, and...

Data from: Drivers of vegetative dormancy across herbaceous perennial plant species

Richard P. Shefferson, Tiiu Kull, Michael J. Hutchings, Marc-André Selosse, Hans Jacquemyn, Kimberly M. Kellett, Eric S. Menges, Richard B. Primack, Juha Tuomi, Kirsi Alahuhta, Sonja Hurskainen, Helen M. Alexander, Derek S. Anderson, Rein Brys, Emilia Brzosko, Slavomir Dostálik, Katharine Gregg, Zdeněk Ipser, Anne Jäkäläniemi, Jana Jersáková, W. Dean Kettle, Melissa K. McCormick, Ana Mendoza, Michael T. Miller, Asbjørn Moen … & Dennis F. Whigham
Vegetative dormancy, that is the temporary absence of aboveground growth for ≥ 1 year, is paradoxical, because plants cannot photosynthesise or flower during dormant periods. We test ecological and evolutionary hypotheses for its widespread persistence. We show that dormancy has evolved numerous times. Most species displaying dormancy exhibit life‐history costs of sprouting, and of dormancy. Short‐lived and mycoheterotrophic species have higher proportions of dormant plants than long‐lived species and species with other nutritional modes. Foliage...

Data from: Divergent in shape and convergent in function: adaptive evolution of the mandible in Sub-Antarctic mice

Sabrina Renaud, Ronan Ledevin, Benoît Pisanu, Jean-Louis Chapuis, Petra Quillfeldt & Emilie A. Hardouin
Convergent evolution in similar environments constitutes strong evidence of adaptive evolution. Transported with people around the world, house mice colonized even remote areas, such as Sub-Antarctic islands. There, they returned to a feral way of life, shifting towards a diet enriched in terrestrial macroinvertebrates. Here, we test the hypothesis that this triggered convergent evolution of the mandible, a morphological character involved in food consumption. Mandible shape from four Sub-Antarctic islands was compared to phylogeny, tracing...

Data from: Population genomics of the introduced and cultivated Pacific kelp Undaria pinnatifida: marinas — not farms — drive regional connectivity and establishment in natural rocky reefs

Jaromir Guzinski, Marion Ballenghien, Claire Daguin-Thiébaut, Laurent Lévêque & Frédérique Viard
Ports and farms are well-known primary introduction hotspots for marine non-indigenous species (NIS). The extent to which these anthropogenic habitats are sustainable sources of propagules and influence the evolution of NIS in natural habitats was examined in the edible seaweed Undaria pinnatifida, native to Asia and introduced to Europe in the 1970s. Following its deliberate introduction 40 years ago along the French coast of the English Channel, this kelp is found in three contrasting habitat...

Data from: Immune checkpoint inhibitor–related myositis and myocarditis in patients with cancer

Mehdi Touat, Thierry Maisonobe, Samuel Knauss, Omar Ben Hadj Salem, Baptiste Hervier, Karine Auré, Tali-Anne Szwebel, Nora Kramkimel, Claire Lethrosne, Jean-Frédéric Bruch, Pauline Laly, Jacques Cadranel, Nicolas Weiss, Anthony Béhin, Yves Allenbach, Olivier Benveniste, Timothée Lenglet, Dimitri Psimaras, Werner Stenzel & Sarah Léonard-Louis
Objective: To report the clinicopathological features and outcome of myositis in patients treated with immune checkpoint inhibitors (irMyositis). Methods: We retrospectively analyzed patients diagnosed with irMyositis in tertiary centers in Paris, France, and Berlin, Germany, from January 2015, to July 2017. Main outcomes were clinical manifestations and muscle histology, which included MHC-I, C5b-9, CD3, CD4, CD8, CD20, CD68, PD-1, PD-L1 and PD-L2 immunohistochemical stains. Results: Ten patients with metastatic cancer were included; median age was...

Data from: The function(s) of the bone ornamentation in the crocodylomorph osteoderms: a biomechanical model based on a finite element analysis

François Clarac, Florent Goussard, Vivian De Buffrénil & Vittorio Sansalone
This paper aims at assessing the influence of the bone ornamentation and, specifically, of the associated loss of bone mass on the mechanical response of the crocodylomorph osteoderms. To this aim, we have performed three dimensional modeling and finite element analyses on a sample which includes both extant dry bones and well-preserved fossils tracing back to the Late Triassic. We simulated an external attack under variable angles on the apical surface of each osteoderm and...

Inhibition of Polarity-Regulating Kinase PAR1b contributes to Helicobacter pylori inflicted DNA Double Strand Breaks in Gastric Cells

Andrea Zamperone, David Cohen, Markus Stein, Charlotte Viard & Anne Müsch
The serine/threonine kinase Par1 is a core component of the machinery that sets up polarity in the embryo and regulates cell fate decisions but its role in the homeostasis of adult tissues is poorly understood. Inhibition of Par1 by the bacterium Helicobacter pylori (H. pylori) represents the only established pathology that affects Par1 function in an adult epithelium. Thus, during chronic H. pylori infection of the gastric mucosa Par1 is one of the targets of...

Data from: Reduction of baseline corticosterone secretion correlates with climate warming and drying across wild lizard populations

Andréaz Dupoué, Alexis Rutschmann, Jean F. Le Galliard, Jean Clobert, Pauline Blaimont, Barry Sinervo, Donald B. Miles, Claudy Haussy & Sandrine Meylan
1. Climate change should lead to massive loss of biodiversity in most taxa but the detailed physiological mechanisms underlying population extinction remain largely elusive so far. In vertebrates, baseline levels of hormones such as glucocorticoids (GCs) may be indicators of population state since their secretion to chronic stress can impair survival and reproduction. However, the relationship between GC secretion, climate change and population extinction risk remains unclear. 2. In this study we investigated whether levels...

Data from: Valproic acid is protective in cellular and worm models of oculopharyngeal muscular dystrophy

Aida Abu-Baker, Alex Parker, Siriram Ramalingam, Janet Laganiere, Bernard Brais, Christian Neri, Patrick Dion & Guy Rouleau
Objective: To explore valproic acid (VPA) as a potentially beneficial drug in cellular and worm models of oculopharyngeal muscular dystrophy (OPMD). Methods: Using a combination of live cell imaging and biochemical measures, we evaluated the potential protective effect of VPA in a stable C2C12 muscle cell model of OPMD, in lymphoblastoid cell lines derived from patients with OPMD and in a transgenic Caenorhabditis elegans OPMD model expressing human mutant PABPN1. Results: We demonstrated that VPA...

Data from: Stabilizing selection, mutational bias and the evolution of sex

Eloïse Vanhoenacker, Linnéa Sandell & Denis Roze
Stabilizing selection around a fixed phenotypic optimum is expected to disfavor sexual reproduction, since asexually reproducing organisms can maintain a higher fitness at equilibrium, while sex disrupts combinations of compensatory mutations. This conclusion rests on the assumption that mutational effects on phenotypic traits are unbiased, that is, mutation does not tend to push phenotypes in any particular direction. In this paper, we consider a model of stabilizing selection acting on an arbitrary number of polygenic...

Registration Year

  • 2018

Resource Types

  • Dataset


  • Sorbonne University
  • French National Centre for Scientific Research
  • University of Antwerp
  • University of Glasgow
  • University of Lyon System
  • Pitié-Salpêtrière Hospital
  • Paul Sabatier University
  • Helmholtz Centre for Environmental Research
  • University of Kansas
  • Charité