135 Works

Data from: Divergent transcriptional responses to low temperature among populations of alpine and lowland species of New Zealand stick insects (Micrarchus)

Luke T. Dunning, Alice B. Dennis, Brent J. Sinclair, Richard D. Newcomb & Thomas R. Buckley
In widespread and genetically-structured populations, temperature variation may lead to among-population differentiation of thermal biology. The New Zealand stick insect genus Micrarchus contains four species that inhabit different thermal environments, two of which are geographically widespread. RNA-Seq and quantitative PCR were used to investigate the transcriptional responses to cold-shock among lowland and alpine species to identify cold-responsive transcripts that differ between the species, and to determine if there is intraspecific geographic variation in gene expression....

Data from: Indirect genetic effects underlie oxygen-limited thermal tolerance within a coastal population of chinook salmon

Nicolas J. Muñoz, Katja Anttila, Zhongqi Chen, John W. Heath, Anthony P. Farrell, Bryan D. Neff & N. J. Munoz
With global temperatures projected to surpass the limits of thermal tolerance for many species, evaluating the heritable variation underlying thermal tolerance is critical for understanding the potential for adaptation to climate change. We examined the evolutionary potential of thermal tolerance within a population of chinook salmon (Oncorhynchus tshawytscha) by conducting a full-factorial breeding design and measuring the thermal performance of cardiac function and the critical thermal maximum (CTmax) of offspring from each family. Additive genetic...

Data from: Eating local: influences of habitat on the diet of little brown bats (Myotis lucifugus)

Elizabeth L Clare, Brittany R Barber, Bernard W Sweeney, Paul DN Hebert & M Brock Fenton
We employ molecular methods to profile the diet of the little brown bat, Myotis lucifugus, and describe spatial and temporal changes in diet over their maternity season. We identified 61 prey species of insects and 5 species of arachnid. The largest proportion of prey (∼32%) were identified as species of the mass-emerging Ephemeroptera (mayfly) genus Caenis. Bats roosting in agricultural settings had lower dietary richness than those occupying a roost located on a forest fragment...

Data from: Basal cold but not heat tolerance constrains plasticity among Drosophila species (Diptera: Drosophilidae)

Casper Nyamukondiwa, John S Terblanche, Katie E Marshall & Brent J Sinclair
Thermal tolerance and its plasticity are important for understanding ectotherm responses to climate change. However, it is unclear whether plasticity is traded off at the expense of basal thermal tolerance and if plasticity is subject to phylogenetic constraints. Here, we investigated associations between basal thermal tolerance and acute plasticity thereof in laboratory-reared adult males of eighteen Drosophila species at low and high temperatures. We determined the high and low temperatures where 90 % of flies...

Data from: Landscape structure and the genetic effects of a population collapse

Serena A. Caplins, Kimberly J. Gilbert, Claudia Ciotir, Jens Roland, Stephen F. Matter & Nusha Keyghobadi
Both landscape structure and population size fluctuations influence population genetics. While independent effects of these factors on genetic patterns and processes are well studied, a key challenge is to understand their interaction, as populations are simultaneously exposed to habitat fragmentation and climatic changes that increase variability in population size. In a population network of an alpine butterfly, abundance declined 60–100% in 2003 because of low over-winter survival. Across the network, mean microsatellite genetic diversity did...

Data from: The diet of Myotis lucifugus across Canada: assessing foraging quality and diet variability

Elizabeth L. Clare, William O. C. Symondson, Hugh Broders, François Fabianek, Erin E. Frazer, Alistair MacKenzie, Andrew Boughen, Rachel Hamilton, Craig K. R. Willis, Felix Martinez-Nuñez, Allyson K. Menzies, Kaleigh J. O. Norquay, Mark Brigham, Joseph Poissant, Jody Rintoul, Robert M. R. Barclay, Jesika P. Reimer & Erin E. Fraser
Variation in prey resources influences the diet and behaviour of predators. When prey become limiting, predators may travel farther to find preferred food or adjust to existing local resources. When predators are habitat limited, local resource abundance impacts foraging success. We analysed the diet of Myotis lucifugus (little brown bats) from Nova Scotia (eastern Canada) to the Northwest Territories (north-western Canada). This distribution includes extremes of season length and temperature and encompasses colonies on rural...

Data from: Resource partitioning by insectivorous bats in Jamaica

Matthew A. Emrich, Elizabeth L. Clare, William O. C. Symondson, Susan E. Koenig & Melville Brock Fenton
In this investigation, we use variation in wing morphology, echolocation behaviour, patterns of habitat use and molecular diet analysis to demonstrate that six species of sympatric insectivorous bats in Jamaica show significant differences that could explain resource partitioning among the species. High-intensity echolocating species that used shorter, broadband signals and had shorter, broader wings (Pteronotus macleayii, Pteronotus quadridens, Mormoops blainvillii) foraged most in edge habitats, but differed in timing of peak activity. P. macleayii and...

Data from: Time scale matters: genetic analysis does not support adaptation-by-time as the mechanism for adaptive seasonal declines in kokanee reproductive lifespan

Yolanda E. Morbey, Evelyn L. Jensen & Michael A. Russello
Seasonal declines of fitness-related traits are often attributed to environmental effects or individual-level decisions about reproductive timing and effort, but genetic variation may also play a role. In populations of Pacific salmon (Oncorhynchus spp.), seasonal declines in reproductive life span have been attributed to adaptation-by-time, in which divergent selection for different traits occurs among reproductively isolated temporal components of a population. We evaluated this hypothesis in kokanee (freshwater obligate Oncorhynchus nerka) by testing for temporal...

Data from: Fearlessness towards extirpated large carnivores may exacerbate the impacts of naïve mesocarnivores

Justin P. Suraci, Devin J. Roberts, Michael Clinchy & Liana Y. Zanette
By suppressing mesocarnivore foraging, the fear large carnivores inspire can be critical to mitigating mesocarnivore impacts. Where large carnivores have declined, mesocarnivores may quantitatively increase foraging, commensurate with reductions in fear. The extirpation of large carnivores may further exacerbate mesocarnivore impacts by causing qualitative changes in mesocarnivore behavior. Error management theory suggests that, where predators are present, prey should be biased towards over-responsiveness to predator cues, abandoning foraging in response to both predator cues and...

Ecological and evolutionary drivers of hemoplasma infection and genotype sharing in a Neotropical bat community

Daniel Becker, Kelly Speer, Alexis Brown, Alex Washburne, Brock Fenton, Sonia Altizer, Daniel Streicker, Raina Plowright, Vladimir Chizhikov, Nancy Simmons & Dmitriy Volokhov
Most emerging pathogens can infect multiple species, underscoring the importance of understanding the ecological and evolutionary factors that allow some hosts to harbor greater infection prevalence and share pathogens with other species. However, our understanding of pathogen jumps is primarily based around viruses, despite bacteria accounting for the greatest proportion of zoonoses. Because bacterial pathogens in bats (Order: Chiroptera) can have conservation and human health consequences, studies that examine the ecological and evolutionary drivers of...

Not a melting pot: plant species aggregate in their non-native range

Gisela C. Stotz, James F. Cahill, Jonathan A. Bennett, Cameron N. Carlyle, Edward W. Bork, Diana Askarizadeh, Sandor Bartha, Carl Beierkuhnlein, Bazartseren Boldgiv, Leslie Brown, Marcelo Cabido, Giandiego Campetella, Stefano Chelli, Ofer Cohen, Sandra Díaz, Lucas Enrico, David Ensing, Batdelger Erdenetsetseg, Alessandra Fidelis, Heath W. Garris, Hugh A.L. Henry, Anke Jentsch, Mohammad Hassan Jouri, Kadri Koorem, Peter Manning … & Lauchlan H. Fraser
Aim: Plant species continue to be moved outside of their native range by human activities. Here, we aim at determining whether, once introduced, plants assimilate into native communities, or whether they aggregate, thus forming mosaics of native- and alien-rich communities. Alien species may aggregate in their non-native range due to shared habitat preferences, such as their tendency to establish in high-biomass, species-poor areas. Location: 22 herbaceous grasslands in 14 countries, mainly in the temperate zone....

Data from: Birdsong signals individual diversity at the major histocompatibility complex

Joel W.G. Slade, Matthew J. Watson, Elizabeth A. MacDougall-Shackleton & J. W. G. Slade
The major histocompatibility complex (MHC) plays a key role in vertebrate immunity, and pathogen-mediated selection often favours certain allelic combinations. Assessing potential mates' MHC profiles may provide receivers with genetic benefits (identifying MHC-compatible mates and producing optimally diverse offspring) and/or material benefits (identifying optimally diverse mates capable of high parental investment). Oscine songbirds learn songs during early life, such that song repertoire content can reflect population of origin while song complexity can reflect early life...

Data from: Buzz factor or innovation potential: what explains cryptocurrencies' returns?

Sha Wang & Jean-Philippe Vergne
Cryptocurrencies have become increasingly popular since the introduction of bitcoin in 2009. In this paper, we identify factors associated with variations in cryptocurrencies’ market values. In the past, researchers argued that the “buzz” surrounding cryptocurrencies in online media explained their price variations. But this observation obfuscates the notion that cryptocurrencies, unlike fiat currencies, are technologies entailing a true innovation potential. By using, for the first time, a unique measure of innovation potential, we find that...

Data from: Livestock abundance predicts vampire bat demography, immune profiles, and bacterial infection risk

Daniel J. Becker, Gábor Á. Czirják, Dmitriy V. Volokhov, Alexandra B. Bentz, Jorge E. Carrera, Melinda S. Camus, Kristen J. Navara, Vladimir E. Chizhikov, M. Brock Fenton, Nancy B. Simmons, Sergio E. Recuenco, Amy T. Gilbert, Sonia Altizer & Daniel G. Streicker
Human activities create novel food resources that can alter wildlife–pathogen interactions. If resources amplify or dampen pathogen transmission likely depends on both host ecology and pathogen biology, but studies that measure responses to provisioning across both scales are rare. We tested these relationships with a four-year study of 369 common vampire bats across ten sites in Peru and Belize that differ in the abundance of livestock, an important anthropogenic food source. We quantified innate and...

Data from: Evaluation of sex differences in the stopover behavior and postdeparture movements of wood-warblers

Yolanda E. Morbey, Christopher G. Guglielmo, Philip D. Taylor, Ivan Maggini, Jessica Deakin, Stuart A. Mackenzie, J. Morgan Brown & Lin Zhao
Sex differences in the behaviors underlying avian protandry, where males arrive at breeding areas earlier than females, are still poorly understood for most species. We tested for sex differences in stopover behavior, refueling rates, and post-departure movements during spring migration in two consecutive years in wood-warblers (Parulidae) at a coastal site on Lake Erie, Ontario, using automated radio telemetry (black-throated blue warblers Setophaga caerulescens and magnolia warblers S. magnolia) and analysis of plasma metabolites as...

Data from: Limited genetic evidence for host plant-related differentiation in the Western cherry fruit fly Rhagoletis indifferens (Diptera: Tephritidae)

Gilbert Saint Jean, Glen R. Hood, Scott P. Egan, Thomas H.Q. Powell, Hannes Schuler, Meredith M. Doellman, Mary M. Glover, James J. Smith, Wee L. Yee, Robert B. Goughnour, Howard M.A. Thistlewood, Sheri A. Maxwell, Nusha Keyghobadi, Juan Rull, Martin Aluja, Jeffrey L. Feder & Thomas H. Q. Powell
The shift of the fruit fly Rhagoletis pomonella (Walsh) in the mid-1800s from downy hawthorn, Crataegus mollis (Torrey & Asa Gray) Scheele, to introduced domesticated apple, Malus domestica (Borkhausen), in the eastern USA is a model for ecological divergence with gene flow. A similar system may exist in the northwestern USA and British Columbia, Canada, where Rhagoletis indifferens Curran (Diptera: Tephritidae) attacks the native bitter cherry Prunus emarginata (Douglas ex Hooker) Eaton (Rosaceae). Populations of...

Metabolic cost of freeze-thaw and source of CO2 production in the freeze-tolerant cricket Gryllus veletis

Adam Smith, Kurtis Turnbull, Julian Moulton & Brent Sinclair
Freeze-tolerant insects can survive the conversion of a substantial portion of their body water to ice. While the process of freezing induces active responses from some organisms, these responses appear absent from freeze-tolerant insects. Recovery from freezing likely requires energy expenditure to repair tissues and re-establish homeostasis, which should be evident as elevations in metabolic rate after thaw. We measured carbon dioxide (CO2) production in the spring field cricket (Gryllus veletis) as a proxy for...

Host life-history traits influence the distribution of prophages and the genes they carry

Tyler Pattenden, Christine Eagles & Lindi Wahl
Bacterial strains with a short minimal doubling time – “fast-growing” hosts – are more likely to contain prophages than their slow-growing counterparts. Pathogenic bacterial species are likewise more likely to carry prophages. We develop a bioinformatics pipeline to examine the distribution of prophages in fast- and slow-growing lysogens, and pathogenic and non-pathogenic lysogens, analysing both prophage length and gene content for each class. By fitting these results to a mathematical model of the evolutionary forces...

Endogenous biomarkers reveal diet partitioning among three sympatric species of swallows

Kaelyn Bumelis, Michael Cadman & Keith Hobson
Since the early 1990s, aerial insectivorous birds have shown serious population declines in North America, but it is not clear if factors common to all species within this guild account for these declines. Among sympatric swallows, population trends differ, and this may be due to differences in ecology operating throughout the annual cycle. Although these species all feed on aerial insects, prey taxa can differ tremendously in their “aeroecology” and use by swallows. We examined...

Data from: Selection bias in mutation accumulation

Lindi Wahl & Deepa Agashe
Mutation accumulation (MA) experiments, in which de novo mutations are sampled and subsequently characterized, are an essential tool in understanding the processes underlying evolution. In microbial populations, MA protocols typically involve a period of population growth between severe bottlenecks, such that a single individual can form a visible colony. While it has long been appreciated that the action of positive selection during this growth phase cannot be eliminated, it is typically assumed to be negligible....

Additional file 2 of Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experiments

Jun Su, Yue Li, Qing Liu, Gang Peng, Chaoying Qin & Yang Li
Additional file 2: Fig. S2. The predictivity of 12 DE-MRGs model for other cancers. A The univariate cox analysis showed that the risk score, based on our 12 DE-MRGs, significantly associated with other 12 types of TCGA cancers. B Kaplan–Meier curves for OS in the other 12 types of TCGA cancers. The patients were divided in to high- and low-risk groups based on the median value of risk score.

Additional file 5 of Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experiments

Jun Su, Yue Li, Qing Liu, Gang Peng, Chaoying Qin & Yang Li
Additional file 5: Fig. S5. Validation of the association between risk score and immune cell infiltration. A Scatter plot showed the positive correlation between the risk score and ImmuneScore (Spearman’s rank correlation coefficient) in the GSE16011 GBM cohort. B Scatter plot showed the positive correlation between the risk score and StromalScore (Spearman’s rank correlation coefficient) in the GSE16011 GBM cohort. C Scatter plot showed the positive correlation between the risk score and ESTAMEScore (Spearman’s rank...

Additional file 10 of Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experiments

Jun Su, Yue Li, Qing Liu, Gang Peng, Chaoying Qin & Yang Li
Additional file 10: Table S5. GO enrichment analysis by using DAVID.

Additional file 6 of Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experiments

Jun Su, Yue Li, Qing Liu, Gang Peng, Chaoying Qin & Yang Li
Additional file 6: Table S1. The mitochondria-related genes extracted from the uniprot database.

Additional file 9 of Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experiments

Jun Su, Yue Li, Qing Liu, Gang Peng, Chaoying Qin & Yang Li
Additional file 9: Table S4. The 21 prognositc DE-MRGs based on the TCGA GBM cohort.

Registration Year

  • 2022
    32
  • 2021
    15
  • 2020
    16
  • 2019
    8
  • 2018
    10
  • 2017
    12
  • 2016
    9
  • 2015
    8
  • 2014
    10
  • 2013
    7

Resource Types

  • Dataset
    117
  • Text
    14
  • Collection
    2
  • Journal Article
    2

Affiliations

  • Western University
    135
  • McGill University
    25
  • Tianjin Medical University General Hospital
    22
  • Sixth Affiliated Hospital of Sun Yat-sen University
    22
  • Sun Yat-sen University
    22
  • Jiangxi Agricultural University
    22
  • Central South University
    22
  • Northwest University
    22
  • Henry Ford Hospital
    22
  • Guangzhou Women and Children Medical Center
    22