488 Works

Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy

Yanan Chen, Hao Zhang, Yue Li, Shuli Ji, Peilu Jia & Tian Wang
Abstract Background Endoplasmic reticulum (ER) stress and autophagy are implicated in the pathophysiology of intestinal inflammation; however, their roles in intrauterine growth retardation (IUGR)-induced colon inflammation are unclear. This study explored the protective effects of natural stilbene pterostilbene on colon inflammation using the IUGR piglets and the tumor necrosis factor alpha (TNF-α)-treated human colonic epithelial cells (Caco-2) by targeting ER stress and autophagy. Results Both the IUGR colon and the TNF-α-treated Caco-2 cells exhibited inflammatory...

sj-pdf-1-cjk-10.1177_20543581221131201 – Supplemental material for Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD): Statistical Analysis Plan of a Registry-Based, Cluster-Randomized Clinical Trial

Stephanie N. Dixon, Kyla L. Naylor, Seychelle Yohanna, Susan McKenzie, Dmitri Belenko, Peter G Blake, Candice Coghlan, Rebecca Cooper, Lori Elliott, Leah Getchell, Vincent Ki, Istvan Mucsi, Gihad Nesrallah, Rachel E. Patzer, Justin Presseau, Marian Reich, Jessica M. Sontrop, Darin Treleaven, Amy D. Waterman, Jeffrey Zaltzman & Amit X. Garg
Supplemental material, sj-pdf-1-cjk-10.1177_20543581221131201 for Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD): Statistical Analysis Plan of a Registry-Based, Cluster-Randomized Clinical Trial by Stephanie N. Dixon, Kyla L. Naylor, Seychelle Yohanna, Susan McKenzie, Dmitri Belenko, Peter G Blake, Candice Coghlan, Rebecca Cooper, Lori Elliott, Leah Getchell, Vincent Ki, Istvan Mucsi, Gihad Nesrallah, Rachel E. Patzer, Justin Presseau, Marian Reich, Jessica M. Sontrop, Darin Treleaven, Amy D. Waterman, Jeffrey Zaltzman and Amit X. Garg...

Targeted OUM1/PTPRZ1 silencing and synergetic CDT/enhanced chemical therapy toward uveal melanoma based on a dual-modal imaging-guided manganese metal–organic framework nanoparticles

Yue Li, Fang Li, Hui Pan, Xiaolin Huang, Jie Yu, Xueru Liu, Qinghao Zhang, Caiwen Xiao, He Zhang & Leilei Zhang
Abstract Metastasis and chemical resistance are the most serious problems in the treatment of highly aggressive uveal melanoma (UM). The newly identified lncRNA OUM1 is overexpressed in UM, functions as a catalyst and regulates protein tyrosine phosphatase (PTP) activity by binding to PTP receptor type Z1 (PTPRZ1), which plays an important role in cell proliferation, metastasis and chemotherapy resistance in the UM microenvironment. Hence, siRNAs that selectively knocking down the lncRNA OUM1 (siOUM1) and its...

Additional file 1 of SWI/SNF complex gene variations are associated with a higher tumor mutational burden and a better response to immune checkpoint inhibitor treatment: a pan-cancer analysis of next-generation sequencing data corresponding to 4591 cases

Yue Li, Xinhua Yang, Weijie Zhu, Yuxia Xu, Jiangjun Ma, Caiyun He & Fang Wang
Additional file 1: Fig. S1 The distributions of variant allele frequencies (VAFs) of ARID1A, ARID1B, ARID2, PBRM1, SMARCA4, and SMARCB1. The median VAFs of the above genes were 16.1%, 13.4%, 13.3%, 17.2%, 15.2%, and 16.7%, respectively. Red solid line, median; black dotted line, quartiles.

Additional file 3 of SWI/SNF complex gene variations are associated with a higher tumor mutational burden and a better response to immune checkpoint inhibitor treatment: a pan-cancer analysis of next-generation sequencing data corresponding to 4591 cases

Yue Li, Xinhua Yang, Weijie Zhu, Yuxia Xu, Jiangjun Ma, Caiyun He & Fang Wang
Additional file 3: Fig. S3 The signaling pathway enrichment of the variated genes in the SWI/SNF-mutant tumors by GO analysis. The GO analysis was performed on all the mutated genes in 1001 SWI/SNF-mutant samples.

Additional file 4 of SWI/SNF complex gene variations are associated with a higher tumor mutational burden and a better response to immune checkpoint inhibitor treatment: a pan-cancer analysis of next-generation sequencing data corresponding to 4591 cases

Yue Li, Xinhua Yang, Weijie Zhu, Yuxia Xu, Jiangjun Ma, Caiyun He & Fang Wang
Additional file 4: Table S1. Synthetic lethal interactive pairs and chemical inhibitors involving SWI/SNF members.

Additional file 10 of Comparative transcriptomic analysis provides insights into the molecular basis underlying pre-harvest sprouting in rice

Dong Liu, Mingyang Zeng, Yan Wu, Yanli Du, Jianming Liu, Shaoqiang Luo & Yongjun Zeng
Additional file 10: Table S9. The list of representative DEGs related to phytohormone metabolism and signalling.

Additional file 14 of Comparative transcriptomic analysis provides insights into the molecular basis underlying pre-harvest sprouting in rice

Dong Liu, Mingyang Zeng, Yan Wu, Yanli Du, Jianming Liu, Shaoqiang Luo & Yongjun Zeng
Additional file 14: Table S13. The general information of sequencing reads and reads that mapped to the reference genome.

Additional file 3 of Comparative transcriptomic analysis provides insights into the molecular basis underlying pre-harvest sprouting in rice

Dong Liu, Mingyang Zeng, Yan Wu, Yanli Du, Jianming Liu, Shaoqiang Luo & Yongjun Zeng
Additional file 3: Table S2. The list of annotated DEGs identified in MXXZ-T vs. MXXZ-C.

Additional file 4 of Comparative transcriptomic analysis provides insights into the molecular basis underlying pre-harvest sprouting in rice

Dong Liu, Mingyang Zeng, Yan Wu, Yanli Du, Jianming Liu, Shaoqiang Luo & Yongjun Zeng
Additional file 4: Table S3. The list of annotated DEGs identified in MXXZ-C vs. JXZ-C.

Additional file 9 of Comparative transcriptomic analysis provides insights into the molecular basis underlying pre-harvest sprouting in rice

Dong Liu, Mingyang Zeng, Yan Wu, Yanli Du, Jianming Liu, Shaoqiang Luo & Yongjun Zeng
Additional file 9: Table S8. Summary of GO results of the DEGs in MXXZ-T vs. MXXZ-C.

Figure S3

Narges Alipanah-Lechner, Lucile Neyton, Eran Mick, Andrew Willmore, Aleksandra Leligdowicz, Kevin Contrepois, Alejandra Jauregui, Hanjing Zhuo, Carolyn Hendrickson, Antonio Gomez, Pratik Sinha, Kirsten N. Kangelaris, Kathleen D. Liu, Michael A. Matthay, Angela Rogers & Carolyn S. Calfee
Predicted survival at any time point during the 60-day study period stratified by metabolite group designation. Top panel shows predicted survival in the hyperinflammatory group compared to the hypoinflammatory group in patients with a Group 1 metabolite group designation (n=28): hazard ratio (HR) for death 3.7 (95%CI 1.4 to 10.1, p-value 0.01). Middle panel shows predicted survival in the hyperinflammatory group compared to the hypoinflammatory group in patients with a Group 2 metabolite group designation...

Falls in Patients With Communication Disability Secondary to Stroke

Rebecca Sullivan, Katherine Harding, Ian Skinner & Bronwyn Hemsley
Patients with stroke are at high risk of falls during inpatient rehabilitation admission. Communication disability is common following stroke; however, this population is often excluded from falls research. This study aimed to examine the falls of patients with communication disability following stroke, including the circumstances, contributing factors, and outcomes of the fall. This medical record review used the Generic Reference Model of patient safety as the analytical lens and data were analyzed descriptively. The study...

sj-spv-3-hpq-10.1177_13591053221144977 – for Using a protection motivation theory framework to reduce vaping intention and behaviour in Canadian university students who regularely vape: A randomized controlled trial

Babac Salmani & Harry Prapavessis
j-spv-3-hpq-10.1177_13591053221144977 for Using a protection motivation theory framework to reduce vaping intention and behaviour in Canadian university students who regularely vape: A randomized controlled trial by Babac Salmani and Harry Prapavessis in Journal of Health Psychology

sj-spv-4-hpq-10.1177_13591053221144977 – for Using a protection motivation theory framework to reduce vaping intention and behaviour in Canadian university students who regularely vape: A randomized controlled trial

Babac Salmani & Harry Prapavessis
sj-spv-4-hpq-10.1177_13591053221144977 for Using a protection motivation theory framework to reduce vaping intention and behaviour in Canadian university students who regularely vape: A randomized controlled trial by Babac Salmani and Harry Prapavessis in Journal of Health Psychology

sj-spv-4-hpq-10.1177_13591053221144977 – for Using a protection motivation theory framework to reduce vaping intention and behaviour in Canadian university students who regularely vape: A randomized controlled trial

Babac Salmani & Harry Prapavessis
sj-spv-4-hpq-10.1177_13591053221144977 for Using a protection motivation theory framework to reduce vaping intention and behaviour in Canadian university students who regularely vape: A randomized controlled trial by Babac Salmani and Harry Prapavessis in Journal of Health Psychology

sj-spv-5-hpq-10.1177_13591053221144977 – for Using a protection motivation theory framework to reduce vaping intention and behaviour in Canadian university students who regularely vape: A randomized controlled trial

Babac Salmani & Harry Prapavessis
sj-spv-5-hpq-10.1177_13591053221144977 for Using a protection motivation theory framework to reduce vaping intention and behaviour in Canadian university students who regularely vape: A randomized controlled trial by Babac Salmani and Harry Prapavessis in Journal of Health Psychology

Using a protection motivation theory framework to reduce vaping intention and behaviour in Canadian university students who regularely vape: A randomized controlled trial

Babac Salmani & Harry Prapavessis
Using Protection Motivation Theory (PMT), we examined the effect of threat appraisal information (perceived vulnerability-PV and perceived severity-PS) to reduce vaping intentions, and in turn reduce vaping use. Canadian university students (n = 77) who vape regularly were randomized to either PMT or attention control treatment conditions. Data were collected at baseline and 3 time points after the intervention: Day 7, Day 30, and Day 45. Participants assigned to the PMT group showed significant increases...

sj-docx-3-cpa-10.1177_07067437221147443 - Supplemental material for Neuropsychiatric Symptom Burden across Neurodegenerative Disorders and its Association with Function

Daniel Kapustin, Shadi Zarei, Wei Wang, Malcolm A. Binns, Paula M. McLaughlin, Agessandro Abrahao, Sandra E. Black, Michael Borrie, David Breen, Leanna Casaubon, Dar Dowlatshahi, Elizabeth Finger, Corinne E Fischer, Andrew Frank, Morris Freedman, David Grimes, Ayman Hassan, Mandar Jog, Donna Kwan, Anthony Lang, Brian Levine, Jennifer Mandzia, Connie Marras, Mario Masellis, Joseph B. Orange … & Sanjeev Kumar
Supplemental material, sj-docx-3-cpa-10.1177_07067437221147443 for Neuropsychiatric Symptom Burden across Neurodegenerative Disorders and its Association with Function by Daniel Kapustin, Shadi Zarei, Wei Wang, Malcolm A. Binns, Paula M. McLaughlin, Agessandro Abrahao, Sandra E. Black, Michael Borrie, David Breen, Leanna Casaubon, Dar Dowlatshahi, Elizabeth Finger, Corinne E Fischer, Andrew Frank, Morris Freedman, David Grimes, Ayman Hassan, Mandar Jog, Donna Kwan, Anthony Lang, Brian Levine, Jennifer Mandzia, Connie Marras, Mario Masellis, Joseph B. Orange, Stephen Pasternak, Alicia Peltsch,...

Low serum 25-hydroxyvitamin D levels are associated with increased cardiovascular morbidity and mortality

Wei Luo, Dan Xu, Jin Zhang, Yao Zhou, Qin Yang, Qiuju Lv & Zhen Qu
There is controversy about the association between vitamin D and cardiovascular disease (CVD). This article aims to explore the association of serum 25-hydroxyvitaminD (25 OHD) with the risk of CVD. PubMed, EMBASE, Web of Science database, OVID, and Cochrane Library databases (last updated in August 2022) were systematically searched. The relationship between 25OHD and the risk of CVD was assessed by using the 95% confidence intervals (CI) and hazard ratio (HR). The effect model was...

sj-docx-2-cjk-10.1177_20543581221150676 – Supplemental material for Development and Validation of Patient Education Tools for Deprescribing in Patients on Hemodialysis

Thomas Hyunwoo Cho, Patrick C. K. Ng, Melissa J. Lefebvre, Arlene Desjarlais, Dennis McCann, Blair Waldvogel, Marcello Tonelli, Amit X. Garg, JoAnne Wilson, Monica Beaulieu, Judith Marin, Cali Orsulak, Melanie Talson, Monica Sharma, Jordanne Feldberg, Clara Bohm & Marisa Battistella
Supplemental material, sj-docx-2-cjk-10.1177_20543581221150676 for Development and Validation of Patient Education Tools for Deprescribing in Patients on Hemodialysis by Thomas Hyunwoo Cho, Patrick C. K. Ng, Melissa J. Lefebvre, Arlene Desjarlais, Dennis McCann, Blair Waldvogel, Marcello Tonelli, Amit X. Garg, JoAnne Wilson, Monica Beaulieu, Judith Marin, Cali Orsulak, Melanie Talson, Monica Sharma, Jordanne Feldberg, Clara Bohm and Marisa Battistella in Canadian Journal of Kidney Health and Disease

Supplemental Material - Skilled Nursing Facility Participation in Bundled Payments Was Related to Small Increases in Nurse Staffing Levels

Meiling Ying, Helena Temkin-Greener, Caroline P. Thirukumaran, Karen E. Joynt Maddox, Robert G. Holloway & Yue Li
Supplemental Material for Skilled Nursing Facility Participation in Bundled Payments was Related to Small Increases in Nurse Staffing Levels by Meiling Ying, Helena Temkin-Greener, Caroline P. Thirukumaran, Karen E. Joynt Maddox, Robert G. Holloway, and Yue Li in Journal of Applied Gerontology.

Data from: NREM2 and sleep spindles are instrumental to the consolidation of motor sequence memories

Samuel Laventure, Stuart Fogel, Ovidiu Lungu, Geneviève Albouy, Pénélope Sévigny-Dupont, Catherine Vien, Chadi Sayour, Julie Carrier, Habib Benali & Julien Doyon
Although numerous studies have convincingly demonstrated that sleep plays a critical role in motor sequence learning (MSL) consolidation, the specific contribution of the different sleep stages in this type of memory consolidation is still contentious. To probe the role of stage 2 non-REM sleep (NREM2) in this process, we used a conditioning protocol in three different groups of participants who either received an odor during initial training on a motor sequence learning task and were...

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