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Additional file 5 of Machine learning algorithms to identify cluster randomized trials from MEDLINE and EMBASE

Ahmed A. Al-Jaishi, Monica Taljaard, Melissa D. Al-Jaishi, Sheikh S. Abdullah, Lehana Thabane, P. J. Devereaux, Stephanie N. Dixon & Amit X. Garg
Additional file 5. Continuous skip-gram architecture.

Additional file 10 of Machine learning algorithms to identify cluster randomized trials from MEDLINE and EMBASE

Ahmed A. Al-Jaishi, Monica Taljaard, Melissa D. Al-Jaishi, Sheikh S. Abdullah, Lehana Thabane, P. J. Devereaux, Stephanie N. Dixon & Amit X. Garg
Additional file 10. Examples of titles and abstracts that were classified incorrectly by our algortihms.

Additional file 3 of Machine learning algorithms to identify cluster randomized trials from MEDLINE and EMBASE

Ahmed A. Al-Jaishi, Monica Taljaard, Melissa D. Al-Jaishi, Sheikh S. Abdullah, Lehana Thabane, P. J. Devereaux, Stephanie N. Dixon & Amit X. Garg
Additional file 3: Fig. S1. A general architecture for a convolutional neural work used for text classification.

LINC02535/miR-30a-5p/GALNT3 axis contributes to lung adenocarcinoma progression via the NF- κ B signaling pathway

Yue Li, Jian Zhao, Weijie Zhang, Anqi Wang, Min Jiao, Xin Cai, Jianjie Zhu, Zeyi Liu & Jian-an Huang
Long non-coding RNAs (LncRNA) play important roles in multiple types of cancers. We addressed the role of LINC02535 by regulating the miR-30a-5p /GalNAc Transferase 3 (GALNT3) axis to promote the proliferation, migration, and invasion in lung adenocarcinoma (LUAD) cells. The Cancer Genome Atlas (TCGA) database screened differentially expressed lncRNAs. Quantitative real-time PCR analysis (qRT-PCR) confirmed that LINC02535 is highly expressed in LUAD tissues and cells. In vitro experiments showed that LINC02535 promotes the proliferation, migration,...

Examining gait aid use and user safety by older people with dementia: Perspectives of informal carers to inform practice

Keith D. Hill, Claudia Meyer, Elissa Burton, Susan W. Hunter, Plaiwan Suttanon, Helen Dawes & Den-Ching A. Lee
To determine gait aid use and decision-making related to usage in people with dementia, and examine factors influencing (1) gait aid use or not; and (2) falls in past year. A survey of informal carers of older people with dementia in the community. Closed questions on gait aid use, falls, timing and sources of gait aid acquisition, and advice received to support use were used. Chi-squared tests (Fisher’s Exact) compared: (1) gait aid users vs...

sj-pdf-9-hpq-10.1177_13591053221144977 – Supplemental material for Using a protection motivation theory framework to reduce vaping intention and behaviour in Canadian university students who regularely vape: A randomized controlled trial

Babac Salmani & Harry Prapavessis
Supplemental material, sj-pdf-9-hpq-10.1177_13591053221144977 for Using a protection motivation theory framework to reduce vaping intention and behaviour in Canadian university students who regularely vape: A randomized controlled trial by Babac Salmani and Harry Prapavessis in Journal of Health Psychology

sj-pdf-9-hpq-10.1177_13591053221144977 – Supplemental material for Using a protection motivation theory framework to reduce vaping intention and behaviour in Canadian university students who regularely vape: A randomized controlled trial

Babac Salmani & Harry Prapavessis
Supplemental material, sj-pdf-9-hpq-10.1177_13591053221144977 for Using a protection motivation theory framework to reduce vaping intention and behaviour in Canadian university students who regularely vape: A randomized controlled trial by Babac Salmani and Harry Prapavessis in Journal of Health Psychology

sj-spv-1-hpq-10.1177_13591053221144977 – for Using a protection motivation theory framework to reduce vaping intention and behaviour in Canadian university students who regularely vape: A randomized controlled trial

Babac Salmani & Harry Prapavessis
sj-spv-1-hpq-10.1177_13591053221144977 for Using a protection motivation theory framework to reduce vaping intention and behaviour in Canadian university students who regularely vape: A randomized controlled trial by Babac Salmani and Harry Prapavessis in Journal of Health Psychology

sj-spv-2-hpq-10.1177_13591053221144977 – for Using a protection motivation theory framework to reduce vaping intention and behaviour in Canadian university students who regularely vape: A randomized controlled trial

Babac Salmani & Harry Prapavessis
sj-spv-2-hpq-10.1177_13591053221144977 for Using a protection motivation theory framework to reduce vaping intention and behaviour in Canadian university students who regularely vape: A randomized controlled trial by Babac Salmani and Harry Prapavessis in Journal of Health Psychology

sj-spv-6-hpq-10.1177_13591053221144977 – for Using a protection motivation theory framework to reduce vaping intention and behaviour in Canadian university students who regularely vape: A randomized controlled trial

Babac Salmani & Harry Prapavessis
-spv-6-hpq-10.1177_13591053221144977 for Using a protection motivation theory framework to reduce vaping intention and behaviour in Canadian university students who regularely vape: A randomized controlled trial by Babac Salmani and Harry Prapavessis in Journal of Health Psychology

sj-xlsx-7-hpq-10.1177_13591053221144977 – for Using a protection motivation theory framework to reduce vaping intention and behaviour in Canadian university students who regularely vape: A randomized controlled trial

Babac Salmani & Harry Prapavessis
sj-xlsx-7-hpq-10.1177_13591053221144977 for Using a protection motivation theory framework to reduce vaping intention and behaviour in Canadian university students who regularely vape: A randomized controlled trial by Babac Salmani and Harry Prapavessis in Journal of Health Psychology

Data from: The effects of dietary macronutrients on flight ability, energetics, and fuel metabolism of yellow-rumped warblers Setophaga coronata

Christopher G. Guglielmo, Alexander R. Gerson, Edwin R. Price & Quentin R. Hays
The catabolism of protein from organs and muscles during migratory flight is necessary to produce glucose, key metabolic intermediates, and water, but may have negative effects on flight range and refueling at stopovers. We tested the hypothesis, suggested by previous studies, that birds that eat high-protein insect diets use more protein for fuel in flight than those that eat high-carbohydrate fruits. First, we fed migratory yellow-rumped warblers synthetic fruit or mixed insect/fruit diets, and measured...

Data from: An increase in immature β-cells lacking Glut2 precedes the expansion of β-cell mass in the pregnant mouse

Christine A. Beamish, Linhao Zhang, Sandra K. Szlapinski, Brenda J. Strutt & David J. Hill
A compensatory increase in β-cell mass occurs during pregnancy to counter the associated insulin resistance, and a failure in adaptation is thought to contribute to gestational diabetes. Insulin-expressing but glucose-transporter-2-low (Ins+Glut2LO) progenitor cells are present in mouse and human pancreas, being predominantly located in extra-islet β-cell clusters, and contribute to the regeneration of the endocrine pancreas following induced ablation. We therefore sought to investigate the contribution of Ins+Glut2LO cells to β-cell mass expansion during pregnancy....

Responses of White-throated sparrows to simulated winter storm cues

Scott MacDougall-Shackleton & Andrea Boyer
These data were used in the publication "Increased frequency of exposure to simulated winter storm cues negatively affects white-throated sparrows (Zonotrichia albicollis)" Front. Ecol. Evol. | doi: 10.3389/fevo.2020.00222 Climate change is causing changes in weather patterns and more frequent extreme weather events. Although birds are often able to cope with and respond to inclement weather with physiological and behavioral responses, as weather events become more severe or frequent the adaptive coping responses of many species...

Supplementary Documentation - Epilepsy risk among survivors of intensive care unit hospitalization for sepsis

Tresah Antaya, Britney Allen, Lucie Richard, Salimah Shariff, Gustavo Saposnik & Jorge Burneo
Objective Our objectives were to determine if survivors of intensive care unit (ICU) hospitalizations with sepsis experience higher epilepsy risk than survivors of ICU hospitalizations without sepsis, and to identify sepsis survivors at highest risk. Methods We used linked, administrative healthcare databases to conduct a population-based, retrospective matched cohort study of adult Ontario residents discharged from an ICU between January 1, 2010 and December 31, 2015, identified using the Discharge Abstract Database. We used propensity...

Data from: Seasonal shifts in the insect gut microbiome are concurrent with changes in cold tolerance and immunity

Laura V. Ferguson, Pranav Dhakal, Jacqueline E. Lebenzon, David E. Heinrichs, Carol Bucking & Brent J. Sinclair
1. Seasonal changes in the environment, such as varying temperature, have the potential to change the functional relationship between ectothermic animals, such as insects, and their microbiomes. Our objectives were to determine: a) whether seasonal changes in temperature shift the composition of the insect gut microbiome, and b) if changes in the microbiome are concomitant with changes in the physiology of the host, including the immune system and response to cold. 2. We exposed laboratory...

Data from: Purifying selection in the toll-like receptors of song sparrows Melospiza melodia

Martha J. Nelson-Flower, Ryan R. Germain, Elizabeth A. MacDougall-Shackleton, Sabrina S. Taylor & Peter Arcese
Variation in immune gene sequences is known to influence resistance to infectious diseases and parasites, and hence survival and mate choice, across animal taxa. Toll-like receptors (TLRs) comprise one essential gene family in the vertebrate innate immune system, and recognize evolutionarily conserved structures from all major microorganism classes. However, the causes and consequences of TLR variation in passerine birds remain largely unexplored. We examined seven TLR genes in song sparrows (Melospiza melodia), a species that...

Data from: Molecular diet analysis finds an insectivorous desert bat community dominated by resource sharing despite diverse echolocation and foraging strategies

Rowena Gordon, Sally Ivens, Loren K. Ammerman, M. Brock Fenton, Joanne E. Littlefair, John M. Ratcliffe & Elizabeth L. Clare
Interspecific differences in traits can alter the relative niche use of species within the same environment. Bats provide an excellent model to study niche use because they have a wide variety of behavioural, acoustic and morphological traits that may lead to multi-species, functional groups. Predatory bats have been classified by their foraging location (edge, clutter, open space), ability to aerial hawk and/or substrate glean prey and echolocation call design and flexibility, all of which may...

Integrating efficacy and safety of vedolizumab compared with other advanced therapies to assess net clinical benefit of ulcerative colitis treatments: a network meta-analysis

Vipul Jairath, Keith Chan, Karen Lasch, Sam Keeping, Christian Agboton, Aimee Blake & Haridarshan Patel
Objectives: Because only one head-to-head randomized trial of biologics for moderate-to-severe UC has been performed, indirect treatment comparisons remain important. This systematic review and network meta-analysis examined efficacy and safety of biologics and tofacitinib for moderate-to-severe UC, using vedolizumab as reference. Methods: Relevant studies (N = 19) of vedolizumab, adalimumab, infliximab, golimumab, ustekinumab, and tofacitinib were identified. Study design differences were addressed by assessing efficacy outcomes conditional on response at maintenance initiation. Primary analysis used...

Data from: Toxic diffuse isolated cerebellar edema from over-the-counter health supplements

David Dongkyung Kim, Christen L. Shoesmith & Lee-Cyn Ang
Figure e-1. Pathology images of the cerebellar biopsy sample.(Panel A) Biopsy shows cerebellar cortex with dark Purkinje neurons and Purkinje neuron dropout. There is microvacuolation of neuropil and white matter. Features are consistent with ischemic neuronal changes with surrounding edema. Luxol-fast blue/hematoxylin-eosin (Bar = 50 microns). (Panel B) Neurofilament immunohistochemistry highlights collapsed basket cells which emphasize the Purkinje neuron dropout. (Bar = 50 microns).Supplementary Figure.tifTable e-1. Labelled ingredients of each herbal or naturopathic product that...

The role of plant-pollinator interactions in structuring nectar microbial communities

Clara De Vega, Sergio Álvarez-Pérez, Rafael G. Albaladejo, Sandy-Lynn Steenhuisen, Marc-André Lachance, Steve D. Johnson & Carlos M. Herrera
1. Floral nectar harbours a diverse microbiome of yeasts and bacteria that depend predominantly on animal visitors for their dispersal. Since pollinators visit specific sets of flowers and carry their own unique microbiota, we hypothesize that plant species visited by the same set of pollinators may support non-random nectar microbial communities linked together by the type of pollinator. 2. Here we explore the importance of plant-pollinator interactions in the assembly of nectar microbiome and study...

Data from: Range-wide populations of a long-distance migratory songbird converge during stopover in the tropics

Camila Gomez, Sara L. Guerrero, Alyssa M. FitzGerald, Nicholas J. Bayly, Keith A. Hobson & Carlos Daniel Cadena
Geographic convergence during migration influences the extent to which animal populations may experience carry-over effects across periods of the annual cycle. When most individuals of a population share geographic areas during a given period, carry-over effects are likely stronger than when individuals occupy multiple areas. We used genetic data and stable isotope (δ2H) measurements from feathers and claws to describe the likely breeding and wintering geographic origins of a long-distance migratory songbird (Gray-cheeked Thrush, Catharus...

Integrating efficacy and safety of vedolizumab compared with other advanced therapies to assess net clinical benefit of ulcerative colitis treatments: a network meta-analysis

Vipul Jairath, Keith Chan, Karen Lasch, Sam Keeping, Christian Agboton, Aimee Blake & Haridarshan Patel
Because only one head-to-head randomized trial of biologics for moderate-to-severe UC has been performed, indirect treatment comparisons remain important. This systematic review and network meta-analysis examined efficacy and safety of biologics and tofacitinib for moderate-to-severe UC, using vedolizumab as reference. Relevant studies (N = 19) of vedolizumab, adalimumab, infliximab, golimumab, ustekinumab, and tofacitinib were identified. Study design differences were addressed by assessing efficacy outcomes conditional on response at maintenance initiation. Primary analysis used fixed-effect models...

Earnings Dynamics and Intergenerational Transmission of Skill

Lance Lochner & Youngmin Park
Intergenerational mobility refers to any change in the social and economic status between generations. It is widely considered a critical component of social justice and an indicator of economic efficiency. A popular way of measuring intergenerational mobility is to assess the persistence of earnings across generations. However, this measure does not necessarily reflect intergenerational mobility in long-run economic status. This is because earnings vary from one year to another due to short-term factors unrelated to...

Data files for: Hazardous loss of genetic diversity through selective sweeps in asexual populations

Lindi Wahl & Mark Tanaka
With the two-fold cost of sex, derived asexual organisms have an immediate reproductive advantage over their sexual sisters. Yet the "twiggy'' phylogenetic distribution of asexual lineages implies that they go extinct relatively quickly over evolutionary time. Meanwhile, bacteria and archaea have persisted for billions of years without requiring sexual reproduction. A simple explanation for this difference is that prokaryotes have very large population sizes that are not subject to the accumulation of deleterious mutations, but...

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