Ecological quality assessment is fundamental to revealing changes in ecological environments before the development of effective ecological conservation policies. The complex ecological environment can be assessed more reliably when multiple remote sensing indices are integrated, such as in the use of the prevalent Remote Sensing-based Ecological Index (RSEI). However, for effective ecological quality assessment, the requirement of acquisition time consistency for images has become an outstanding issue for broadening the application of the RSEI. In...

Additional file1: Fig. S1. OUM1 knockdown impairs UM cell metastasis and proliferation. Fig. S2. GO and pathway function analysis. Fig. S3. Bioinformatics analysis of OUM1 targets. Fig. S4. PTPRZ1 might be a target of OUM1. Fig. S5. Synergistic effect of SOV and OUM1 interference on apoptosis. Fig. S6. In vivo toxicity evaluation. Table S1. Downregulated and Upregulated gene. Table S2. Primers and siRNA used in this study. Table S3. Primers used in RNA-ChIP assay. Details...

We identified relapsing fever (RF) Borrelia in 1.45% (145/10426) of the ticks and 1.40% (40/2850) of the wild mammals in a field investigation in China. Three RF Borrelia species, including human-pathogenic Borrelia miyamotoi, Borrelia persica and unclassified Babesia sp. were determined. Main species determined from ticks was B. miyamotoi (44.14%), followed by the unclassified Borrelia sp. (42.76%), and Borrelia theileri (13.10%). In wild mammals, main species found was B. persica (57.50%), followed by the unclassified...

Additional file 4: Table S1. Synthetic lethal interactive pairs and chemical inhibitors involving SWI/SNF members.

Abstract Background Residents in surgical specialties face a steep hierarchy when managing medical crises. Hierarchy can negatively impact patient safety when team members are reluctant to speak up. Yet, simulation has scarcely been previously utilized to qualitatively explore the way residents in surgical specialities navigate this challenge. The study aimed to explore the experiences of residents in one surgical specialty, obstetrics and gynecology (Ob/Gyn), when challenging hierarchy, with the goal of informing future interventions to...

Additional file 1. Themes and sample illustrative quotations of the communication strategies and coping mechanism categories.

Abstract Background Bamboo has been identified as a potential instrument for socioeconomic development due to its fast growth, perceived environmental benefits, promising material properties, myriad applications, and relative underdevelopment as a global industrial product. Many projects and interventions have been carried out that aim to utilize bamboo’s social and environmental potential in development. However, critical evaluations that demonstrate this effect using real-world evidence and outcomes are rare, and existing case studies have not been collated...

Supplemental material, sj-docx-1-mso-10.1177_20552173221128170 for Autoimmune diseases and cancers overlapping with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD): A systematic review by Negar Molazadeh, Gauruv Bose, Itay Lotan and Michael Levy in Multiple Sclerosis Journal – Experimental, Translational and Clinical

BackgroundMyelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) has various similarities with AQP4-IgG-seropositive Neuromyelitis Optica Spectrum Disorder (AQP4-IgG + NMOSD) in terms of clinical presentations, magnetic resonance imaging (MRI) findings, and response to treatment. But unlike AQP4-IgG + NMOSD, which is known to coexist with various autoimmune diseases and cancers, an association of MOGAD with these conditions is less clear.MethodsWe conducted a systematic search in PubMed, Scopus, Web of Science, and Embase based on the preferred reporting...

Additional file 13: Table S12. The list of representative DEGs related to phenylpropanoid biosynthesis.

Additional file 15: Table S14. Primers used for quantitative real-time PCR in this study.

To summarize the available evidence for the delivery of synchronous virtual rehabilitation intervention services for preschoolers and to identify key factors associated with virtual intervention. Five databases were searched to identify peer-reviewed articles that assessed virtual interventions for preschoolers delivered by rehabilitation health professionals including physical therapists, occupational therapists, speech-language pathologists, audiologists, and their associated assistants. Relevant data regarding demographics, technology, mode of service delivery, timing, engagement, and measurement data were extracted, and charted. Data...

Metabolites with differential abundance in the hyperinflammatory ARDS phenotype compared to the hypoinflammatory phenotype based on unadjusted analyses. Metabolites are listed in order of increasing log2 fold change.

Metabolites with differential abundance in the hyperinflammatory ARDS phenotype compared to the hypoinflammatory phenotype based on unadjusted analyses. Metabolites are listed in order of increasing log2 fold change.

Additional file 4.

Additional file 1.

Additional file 8.

Additional file 1. Case Study Interview Guides.

Analysis of large-scale gene expression post vaccination can provide an overview of immune responses. We used transcriptional approaches to comprehensively analyze the innate immune response signatures elicited by protein subunit (PS) vaccine ZF2001 and an mRNA vaccine named RRV. A fine-grained time-dependent dissection of large-scale gene expression post immunization revealed that ZF001 induced MHC class II-related genes, including cd74 and H2-Aa, more expeditiously than the RRV. Notably, the RRV induced MHC class I-related genes such...

Supplemental material, sj-docx-1-tab-10.1177_1759720X221131604 for Early Osteoarthritis Questionnaire (EOAQ): a tool to assess knee osteoarthritis at initial stage by Alberto Migliore, Liudmila Alekseeva, Sachin R. Avasthi, Raveendhara R. Bannuru, Xavier Chevalier, Thierry Conrozier, Sergio Crimaldi, Gustavo C. de Campos, Demirhan Diracoglu, Gianfranco Gigliucci, Gabriel Herrero-Beaumont, Giovanni Iolascon, Ruxandra Ionescu, Jörg Jerosch, Jorge Lains, Emmanuel Maheu, Souz Makri, Natalia Martusevich, Marco Matucci-Cerinic, Karen Pavelka, Robert J. Petrella, Raghu Raman and Umberto Tarantino in Therapeutic Advances in Musculoskeletal...

Environmental context is a crucial factor that influences sexual communication systems. Particularly in ectotherms, which cannot metabolically regulate their body temperature, temperature has an outsized effect on these intraspecific interactions. Using a desert-dwelling jumping spider Habronattus clypeatus, we assessed how temperature impacts various parts of the male signal and female mate choice for the signal. These spiders have multimodal, temporally-structured courtship displays that begin with visual-only “sidling” displays and proceed to multimodal visual and vibratory...

Two phytochemicals, thymol and thymoquinone obtained from thymes (Thymus vulgaris L., Lamiaceae etc.) and Nagila Sativa seed, respectively. Both the phytochemicals show several biochemical activities like anticancer, antimicrobial etc. In this paper, we studied the affinities of thymol and thymoquinone towards calf thymus DNA (CT-DNA) and protein (bovine serum albumin). Spectroscopic and molecular modelling studies revealed that both compounds have a high affinity toward both the receptors; DNA and protein. Both phytochemicals binds to the...

The seed microbiome of crop wild relatives is a potential reservoir of beneficial traits that potentially improve their host plant resilience to fluctuating environments and pathogenic threats. Herein, we studied the seed microbiome of three species of the medicinal genus Panax (P. vietnamensis, P. japonicas, and P. stipuleanatus) collected from seven locations in Southwest China. We used qPCR and metabarcoding high-throughput sequencing to target both endophytic bacteria and fungi. Seed bacterial absolute abundance (1.1 ×...

Additional file 5: Table S4. The list of annotated DEGs identified in MXXZ-T vs. JXZ-T.

Additional file 5: Table S4. The list of annotated DEGs identified in MXXZ-T vs. JXZ-T.