Focal segmental glomerulosclerosis (FSGS) is a leading cause of kidney diseases worldwide. The prevalence of FSGS, relative to other glomerular disease diagnoses, seems to be increasing worldwide, and it is a major contributor to end-stage renal disease (ESRD). In 2011, McGrogan et al. reported an annual incidence rates of FSGS as 0.2 to 1.8/100, 000 population per year by reviewing literature worldwide.

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The Transparency and Open Promotion (TOP) Guidelines are eight modular recommendations and standards (with varying levels of stringency) for journals and funders to incentivize open science practices. TOP Factor is a transparent evaluation rubric showing the degree of a journal or funder's implementation of and compliance with TOP Guidelines. Visit cos.io/top to view the TOP Guidelines and for more resources for implementing TOP.

We are preregistering an initial study intended to start a new research program. This study will help us determine how long the designed study takes, whether stimuli and measures are well received and show reasonable inter-judge agreement, what potential effect sizes might be for questions of interest and therefore what sample sizes are suitable for the first primary study. We are documenting the basic features of the study, some research questions of interest, some hypotheses,...

This research seeks to develop a new theory of cross-group threat transfer, which conceptualizes how threats attributed to an outgroup can be transferred to other groups or to a broader social category. To test and further develop this theory, research will be conducted in the United States (U.S.) on two cases. The first case will examines the extent to which symbolic and realistic threats attributed to rioters who engaged in violence surrounding the summer 2020...

In this webinar, attendees will learn about both the technical and practical aspects of this collaborative project connecting the researcher tool OSF and the preservation system of Internet Archive. We will demonstrate how researchers can improve the openness and reproducibility of their research through preregistration, and how those preregistrations are preserved with Internet Archive. We will answer questions and seek to learn your needs and use cases for how this powerful workflow can support library...

Protocol for Scoping Review

The purpose of this project is to examine whether people's negative sentiments toward the perpetrator of a microaggression (compared to the perpetrator of a generic norm violation) extend to the entire social group that the violator belongs to. To begin we will focus on gender microaggressions, committed by men on women. We manipulate the kind of norm violation participants are exposed to (a man's microaggression or other norm violation, pretested to be of equal badness...

Interval timing is a fundamental component of action, and is interestingly susceptible to motor-related temporal distortions. Several experiments have shown that temporal expansion and compression can occur in systematic ways with modifications of movement direction, speed, and length. These studies have largely shown that movement biases temporal estimates, but have primarily considered self-modulated movement only. However, real-world encounters often include situations in which movement is restricted or perturbed by environmental factors. Thus, in the following...

Open source infrastructure has paved the way for mission-aligned research stakeholders to create a united vision of interoperable tools and services that accelerate scholarly communication, fill technology gaps, converge solutions, and enable access and discoverability. Hear from a panel of research groups that have taken advantage of interoperable infrastructure to leverage more robust workflows to support rigorous, reproducible research. We also discuss the steps stakeholders and institutions can take to integrate OSF’s open API with...

Rhithropanopeus harrisii is a common estuarine crab native to the East and Gulf Coasts of North America. Here, it is found along a broad range of salinities, spanning from ~1 PSU to ~25 PSU along estuarine gradients. As part of a larger study on the species' potential use of low-salinity refuges from parasitism, we tested for differences in gene expression with salinity using crabs from three distinct estuarine reaches along the Pamlico River in North...

By shuffling biogeographic distributions, biological invasions can both disrupt long-standing associations between hosts and parasites and establish new ones. This creates natural experiments with which to study the ecology and evolution of host-parasite interactions. In estuaries of the Gulf of Mexico, the white-fingered mud crab (Rhithropanopeus harrisii) is infected by a native parasitic barnacle Loxothylacus panopaei (Rhizocephala), which manipulates host physiology and behavior. In the 1960s, L. panopaei was introduced to the Chesapeake Bay and...

The purpose of this study is to understand the psychosocial impact and mediating protective factors of social distancing measures during the COVID-19 pandemic to advance support structures for social distancing practices, guide public health recommendations, and inform mental health resource allocation and support services. This study has two specific aims, first to understand the psychological impact of social distancing measures on overall levels of mental health and second to assess the associations between psychological distress,...

Early Bilingualism and Foreign Language Learning in Secondary School